Human papillomaviruses and non-melanoma skin cancer: basic virology and clinical manifestations.

abstract：BACKGROUND:We aimed to determine whether serum soluble CD30 (sCD30) could identify recipients at high risk for unfavorable early and late kidney transplant outcomes. METHODS:Serum sCD30 was measured on the day of kidney transplantation and on the 4th day posttransplant. We assessed the value of these measurements in p...

journal_title：Disease markers

authors： Trailin AV,Ostapenko TI,Nykonenko TN,Nesterenko SN,Nykonenko OS

更新日期：2017-01-01 00:00:00

abstract：:IGF2 is the first gene discovered to be imprinted and expressed exclusively from the paternal allele in both human and mouse. IGF2 is also the first imprinted gene displaying loss of imprinting (LOI) or aberrant imprinting in human cancers. Evidently, LOI or reactivation of the maternal allele of IGF2 is associated wi...

journal_title：Disease markers

authors： Cui H

更新日期：2007-01-01 00:00:00

abstract：Background:Lactate has been widely used as a risk indicator of outcomes in critically ill patients due to its ready measurement and good predictive ability. However, the interconnections between lactate metabolism and glucose metabolism have not been sufficiently explored, yet. In this study, we aimed to investigate wh...

journal_title：Disease markers

authors： Chen X,Bi J,Zhang J,Du Z,Ren Y,Wei S,Ren F,Wu Z,Lv Y,Wu R

更新日期：2019-11-26 00:00:00

abstract：:The HLA system is deeply involved in susceptibility to a variety of diseases. Relationships between HLA and diseases are of considerable interest and importance, as they provide new tools for studying the inheritance, classification, and pathogenesis of these diseases. Studies on the distribution of HLA antigens in di...

journal_title：Disease markers

authors： Jabbar AA

更新日期：1993-11-01 00:00:00

abstract：:Oncogenic activation of the Wnt/ β -catenin signaling pathway is common in human cancers. The secreted frizzled-related proteins (SFRPs) function as negative regulators of Wnt signaling and have important implications in carcinogenesis. Because there have been no reports about the role of SFRP3 in hepatocellular carci...

journal_title：Disease markers

authors： Lin YW,Shih YL,Lien GS,Suk FM,Hsieh CB,Yan MD

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). METHODS:98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies ...

journal_title：Disease markers

authors： Demarco AL,Rodrigues Mde L,Figueiredo JF,Deghaide NH,de Menezes MB,Demarco LA,Fernandes AP,Donadi EA

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Impaired fasting glucose (IFG) through the nondiabetic range (100-125 mg/dL) is not considered in the cardiovascular (CV) risk profile. AIM:To compare the clustering of CV risk factors (RFs) in nondiabetic subjects with normal fasting glucose (NFG) and IFG. MATERIAL AND METHODS:Cross-sectional study in 373...

journal_title：Disease markers

authors： Valentino G,Kramer V,Orellana L,Bustamante MJ,Casasbellas C,Adasme M,Salazar A,Navarrete C,Acevedo M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis is a monogenic recessive disorder found predominantly in Caucasian population. This disease arises from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. In this study we consider poly T polymorphism c.1210-12T[5], c.1210-12T[7], c.1210-12T[9] (T{5}, T{7}, T{9}...

journal_title：Disease markers

authors： Tabaripour R,Niaki HA,Douki MR,Bazzaz JT,Larijani B,Yaghmaei P

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Stroke subtype diagnosis leads to specific therapies to reduce recurrences. Because nearly one third of patients remain with unknown etiology after a complete screening workup, we aim to investigate whether molecular markers of myocardial damage were associated with cardioembolic stroke and if they were usef...

journal_title：Disease markers

authors： Rodríguez-Yáñez M,Sobrino T,Blanco M,de la Ossa NP,Brea D,Rodríguez-González R,Leira R,Dávalos A,Castillo J

更新日期：2009-01-01 00:00:00

abstract：:Recent experiments have shown that when specific biomolecular interactions are confined to one surface of a microcantilever beam, changes in intermolecular nanomechanical forces provide sufficient differential torque to bend the cantilever beam. This has been used to detect single base pair mismatches during DNA hybri...

journal_title：Disease markers

authors： Majumdar A

更新日期：2002-01-01 00:00:00

abstract：:Clinical variables contribute to the severity of Kashin-Beck disease (KBD). However, it is unclear if there is a correlation between gene expression and clinical variables. Peripheral blood samples were collected from 100 patients with KBD and 100 healthy controls from KBD-endemic areas to identify differentially expr...

journal_title：Disease markers

authors： Wang X,Ning Y,Zhang P,Yang L,Li C,Zhou R,Guo X

更新日期：2019-01-03 00:00:00

abstract：OBJECTIVES:To investigate the expression of estrogen (ER), progesterone receptors (PR), nuclear factor- κ B (NF- κ B), and tumor necrosis factor- α (TNF- α ) in human breast cancer (BC), and the correlation of these four parameters with clinicopathological features of BC. METHODS AND RESULTS:We performed an immunohist...

journal_title：Disease markers

authors： Zhou XL,Fan W,Yang G,Yu MX

更新日期：2014-01-01 00:00:00

abstract：:The total plasma concentration of homocysteine is a marker of this amino acid's atherogenic potential. However, the homocysteine pool exists almost entirely as oxidized homocysteine equivalents (OHcyE), composed of homocystine and cysteine-homocysteine disulphides (20-30%), and protein-bound disulphide (70-80%). We ha...

journal_title：Disease markers

authors： Iuliano M,De Tommaso G,Ragone R

更新日期：2009-01-01 00:00:00

abstract：:Abnormal phenotypic switch of vascular smooth muscle cell (VSMC) is a hallmark of vascular disorders such as atherosclerosis and restenosis. And this process has been related to remodeling of L-type calcium channel (LTCC). We attempted to investigate whether fluvastatin has any effect on VSMC proliferation and LTCCα 1...

journal_title：Disease markers

authors： Ouyang QF,Han Y,Lin ZH,Xie H,Xu CS,Xie LD

更新日期：2014-01-01 00:00:00

abstract：:Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related death, whose patterns vary among geographical regions and ethnicities. It is a multifactorial disease, and its development depends on infection by Helicobacter pylori (H. pylori) and Epstein-Barr virus (EBV), host genetic fact...

journal_title：Disease markers

authors： Sandoval-Bórquez A,Saavedra K,Carrasco-Avino G,Garcia-Bloj B,Fry J,Wichmann I,Corvalán AH

更新日期：2015-01-01 00:00:00

abstract：:A major subtype of childhood lymphoblastic leukemia has been previously defined on the basis of expression of a cell surface marker referred to as the common acute lymphoblastic leukemia antigen. In this study we provide evidence that leukemic cells from most of the patients with common acute lymphoblastic leukemia co...

journal_title：Disease markers

authors： Hanash SM,Kuick R,Nichols D,Stoolman L

更新日期：1988-10-01 00:00:00

abstract：:There is increasing evidence to support the use of CA125 in the follow-up and management of patients with ovarian cancer and several commercial kits are now available for its measurement. This study investigated and compared the performance of three of them: an enzyme immunoassay (EIA) and an immunoradiometric assay (...

journal_title：Disease markers

authors： Fisken J,Leonard RC,Roulston JE

更新日期：1989-01-01 00:00:00

abstract：:Our previous studies using the mass spectrum analysis provided evidence that fibrinopeptide A (FPA) could be a potential biomarker for schizophrenia diagnosis. We sought further to demonstrate that variants in the fibrinogen alpha chain gene (FGA) coded FPA might confer vulnerability to schizophrenia. 1,145 patients w...

journal_title：Disease markers

authors： Rao W,Zhou N,Zhang H,Liu R,Zhang S,Su Y,Yang G,Ma Y,Shi J,Yu Y,Yu Q

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). DESIGN:PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodonti...

journal_title：Disease markers

authors： Priyanka N,Kumari M,Kalra N,Arjun P,Naik SB,Pradeep AR

更新日期：2013-01-01 00:00:00

abstract：Background:The systemic immune-inflammation index (SII), based on peripheral lymphocytes, neutrophils, and platelet count, has been used as a prognostic marker for several tumors. However, use of the SII has not been reported for gastric cancer. Methods:We evaluated the prognostic value of the SII in primary and valid...

journal_title：Disease markers

authors： Shi H,Jiang Y,Cao H,Zhu H,Chen B,Ji W

更新日期：2018-12-02 00:00:00

abstract：:Involvement of the ets-1 proto-oncogene located at chromosome band 11q23 was studied in six tumors and in a congenital chromosome abnormality affecting the 11q23 region, in order to determine whether the breakpoint of these rearrangements was identical at the molecular level. In multiple restriction digestions a 5.4 k...

journal_title：Disease markers

authors： Koduru PR,Offit K,Jhanwar SC

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Despite the many studies examining thyroid cancers, the effect of thyroid autoantibodies on differentiated thyroid carcinoma (DTC) remains unclear. OBJECTIVE:To investigate the association between serologic thyroid autoantibodies (ATAs) and DTC, we retrospectively evaluated data of thyroid nodules obtained ...

journal_title：Disease markers

authors： Qin J,Yu Z,Guan H,Shi L,Liu Y,Zhao N,Shan Z,Han C,Li Y,Teng W

更新日期：2015-01-01 00:00:00

abstract：:Transforming growth factor β1 (TGF-β1) is an important mediator in Chagas disease. Furthermore, patients with higher TGF-β1 serum levels show a worse clinical outcome. Gene polymorphism may account for differences in cytokine production during infectious diseases. We tested whether TGFB1 polymorphisms could be associa...

journal_title：Disease markers

authors： Ferreira RR,Madeira FDS,Alves GF,Chambela MDC,Curvo EOV,Moreira ADS,Almeida de Sá R,Mendonça-Lima L,Cabello PH,Bailly S,Feige JJ,Araujo-Jorge TC,Saraiva RM,Waghabi MC

更新日期：2018-02-18 00:00:00

abstract：:CD4+ T cells of patients with B cell non-Hodgkin's lymphoma (NHL) were analysed for expression of CD45RA and CD29. It was found that CD45RA expression was significantly lower, and CD29 expression significantly higher, in lymphoma patients compared to normal controls. Moreover absolute numbers of CD4+ T cells were sign...

journal_title：Disease markers

authors： Sewell HF,MacKenzie RH,Dawson AA,Ratcliffe MA,King DJ,Bennett NB

更新日期：1990-05-01 00:00:00

abstract：Aim:Increasing evidence indicates that hepatic subcapsular flow (HSF) can serve as a noninvasive ultrasonographic marker for the early diagnosis of biliary atresia (BA). However, results regarding its diagnostic accuracy are inconsistent and inconclusive. We conducted this meta-analysis with an aim to systematically ev...

journal_title：Disease markers

authors： Sun C,Wu B,Pan J,Chen L,Zhi W,Tang R,Zhao D,Guo W,Wang J,Huang S

更新日期：2020-03-01 00:00:00

abstract：Background:The role of the NFKB1 gene rs28362491 polymorphism and NFKBIA gene rs2233406 polymorphism in the development of head and neck cancer (HNC) remains controversial. This meta-analysis was performed to assess the relationship between the gene polymorphisms and HNC quantitatively. Methods:PubMed, Embase, Web of ...

journal_title：Disease markers

authors： Li L,Zhang ZT

更新日期：2019-09-12 00:00:00

abstract：:Renal cell carcinoma (RCC) is one of the most common genitourinary cancers worldwide. Previous evidence shows that long noncoding RNA (LncRNA) APOC1P1 plays an important role in cancer development. However, the role of LncRNA APOC1P1 in ccRCC remains to be explored. LncRNA APOC1P1 expression in 283 ccRCC tissues and 3...

journal_title：Disease markers

authors： Sun C,Zhou Z,Shi H,Li F,Zhang G

更新日期：2019-12-01 00:00:00

abstract：Objective:A growing body of emerging evidence indicates that metabolic processes play a pivotal role in the biological processes underlying acute myocardial infarction (AMI). The aim of the current study was to identify featured metabolism-related genes in patients with AMI using a support vector machine (SVM) and to f...

journal_title：Disease markers

authors： Xie H,Zha E,Zhang Y

更新日期：2020-11-28 00:00:00

abstract：OBJECTIVES:This study was undertaken to investigate the OPG profiles in gingival crevicular fluid (GCF), saliva, and gingival tissues of chronic periodontitis (CP) patients in response to open flap debridement (OFD). SUBJECTS AND METHODS:The study included 30 subjects divided into 2 groups: 20 CP patients and 10 perio...

journal_title：Disease markers

authors： Hassan SH,El-Refai MI,Ghallab NA,Kasem RF,Shaker OG

更新日期：2015-01-01 00:00:00

abstract：:Extra-nodal natural killer T-Cell (NK/T-cell) lymphoma is a progressive cancer with poor prognosis due to the lack of disease specific treatment. To develop specific therapeutic strategies, it is essential to identify tumor markers. Recent studies show that circulating microRNA (miRNA) may serve as diagnostic and/or p...

journal_title：Disease markers

authors： Guo HQ,Huang GL,Guo CC,Pu XX,Lin TY

更新日期：2010-01-01 00:00:00