Phenotypic abnormality of T cells in B cell non-Hodgkin's lymphoma.

Abstract:

:CD4+ T cells of patients with B cell non-Hodgkin's lymphoma (NHL) were analysed for expression of CD45RA and CD29. It was found that CD45RA expression was significantly lower, and CD29 expression significantly higher, in lymphoma patients compared to normal controls. Moreover absolute numbers of CD4+ T cells were significantly lower in NHL patients, due to selective depletion of CD4+ CD45RA+ cells.

journal_name

Dis Markers

journal_title

Disease markers

authors

Sewell HF,MacKenzie RH,Dawson AA,Ratcliffe MA,King DJ,Bennett NB

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

145-9

issue

3

eissn

0278-0240

issn

1875-8630

journal_volume

8

pub_type

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