Formation of nano-hydroxyapatite in gelatin droplets and the resulting porous composite microspheres.

abstract：:Three of the most plausible biological theories of arsenic carcinogenesis are protein binding, oxidative stress and altered DNA methylation. This review presents the role of trivalent arsenicals binding to proteins in arsenic carcinogenesis. Using vacuum filtration based receptor dissociation binding techniques, the l...

journal_title：Journal of inorganic biochemistry

authors： Kitchin KT,Wallace K

更新日期：2008-03-01 00:00:00

abstract：:In an effort to understand the biochemical mechanisms of aluminum-induced neurotoxicity, we investigated the effects of aluminum ion, Al3+, on the Mg(2+)- and nucleotide-dependent protein, ras p21. Picomolar Al3+ concentrations inhibited the GTPase activity of ras p21 in an Mg(2+)-dependent manner, consistent with an ...

journal_title：Journal of inorganic biochemistry

authors： Landino LM,Macdonald TL

更新日期：1997-05-01 00:00:00

abstract：:The reaction of 3-methoxyphenylacetic acid (3-MPAH), 4-methoxyphenylacetic acid (4-MPAH), 2,5-dimethyl-3-furoic acid (DMFUH) or 1,4-benzodioxane-6-carboxylic acid (BZDOH) with triphenyltin(IV) chloride (1:1) or diphenyltin(IV) dichloride (2:1) in the presence of triethylamine yielded the compounds [SnPh3(3-MPA)] (1), ...

journal_title：Journal of inorganic biochemistry

authors： Gómez-Ruiz S,Kaluderović GN,Prashar S,Hey-Hawkins E,Erić A,Zizak Z,Juranić ZD

更新日期：2008-12-01 00:00:00

abstract：:We present hereby an overview of the reactions of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, with ligands (primarily oxygen) and electrons, pointing out where necessary unresolved facts or questionable interpretations. ...

journal_title：Journal of inorganic biochemistry

authors： Brunori M,Giuffrè A,Sarti P

更新日期：2005-01-01 00:00:00

abstract：:The dynamics of iron nuclei in the condensates obtained by interaction of Fe(III) with DNA, Fe(III)(DNA monomer)(2), have been investigated by variable temperature (57)Fe Mössbauer spectroscopy. Studies were effected on gel and freeze-dried samples, obtaining nearly coincident values of the parameters isomer shift and...

journal_title：Journal of inorganic biochemistry

authors： Trotta A,Barbieri Paulsen A,Silvestri A,Ruisi G,Assunta Girasolo M,Barbieri R

更新日期：2002-01-01 00:00:00

abstract：:A series of iminopyridine complexes of platinum(II), bearing a flexible diethereal, aryl terminated residue, where the size of aryl group is varied from phenyl to 9-anthracenyl, was synthesized. The new complexes are soluble and stable in DMSO/H2O mixtures. Besides the metal center, aryl groups are available for furth...

journal_title：Journal of inorganic biochemistry

authors： Bondi R,Dalla Via L,Hyeraci M,Pagot G,Labella L,Marchetti F,Samaritani S

更新日期：2020-12-15 00:00:00

abstract：:In order to investigate the low-dose long-term Cr(VI) action on antioxidant enzymes in cultured mammalian cells we estimated the activity of glutathione dependent antioxidant enzymes, catalase and superoxide dismutase (SOD) under various chromium concentrations in human epithelial-like L-41 cells. The long-term action...

journal_title：Journal of inorganic biochemistry

authors： Asatiani N,Sapojnikova N,Abuladze M,Kartvelishvili T,Kulikova N,Kiziria E,Namchevadze E,Holman HY

更新日期：2004-03-01 00:00:00

abstract：:The stability constants of the mixed ligand complexes of L-dopa, L-tyrosine, L-phenylalanine, and dopamine with copper(II) and nickel(II) ions and with 2,2'-bipyridyl and 1,10-phenanthroline were determined pH-metrically at 25 degrees C and an ionic strength of 0.2 mol/dm3 (KCl). Spectral studies were made to establis...

journal_title：Journal of inorganic biochemistry

authors： Kiss T,Gergely A

更新日期：1985-12-01 00:00:00

abstract：:The polymer-supported oxidovanadium(IV) complex PS-[V(IV)O(sal-dahp)] (2) (PS=chloromethylated polystyrene crosslinked with 5% divinylbenzene, and H3sal-dahp=dibasic pentadentate ligand derived from salicylaldehyde and 1,3-diamino-2-hydroxypropane) was prepared from the corresponding monomeric oxidovanadium(IV) comple...

journal_title：Journal of inorganic biochemistry

authors： Maurya MR,Chaudhary N,Avecilla F,Correia I

更新日期：2015-06-01 00:00:00

abstract：:Zinc is an essential element for nutrition as well as for the proper development and function of brain cells, and its traces are present in a wide range of foods. It is a constituent of many enzyme systems and is an integral part of insulin and of the active site of intracellular enzymes. However, excessive accumulati...

journal_title：Journal of inorganic biochemistry

authors： Suwalsky M,Novoa V,Villena F,Sotomayor CP,Aguilar LF,Ronowska A,Szutowicz A

更新日期：2009-05-01 00:00:00

abstract：:The non-covalent binding of [(en)Pt(mu-dpzm)2Pt(en)]4+ to segments of DNA containing only G and C bases has been studied to gain an understanding of the pre-covalent binding association of cationic polynuclear platinum(II) anti-cancer drugs at G/C sites. 1H-NMR and CD spectroscopy were used to study the binding of the...

journal_title：Journal of inorganic biochemistry

authors： Wheate NJ,Cutts SM,Phillips DR,Aldrich-Wright JR,Collins JG

更新日期：2001-03-01 00:00:00

abstract：:Catalase (CAT) and myeloperoxiase (MPO) are heme-containing enzymes that have attracted attention for their role in the etiology of numerous respiratory disorders such as cystic fibrosis, bronchial asthma, and acute hypoxemic respiratory failure. However, information regarding the interrelationship and competition bet...

journal_title：Journal of inorganic biochemistry

authors： Ali I,Khan SN,Chatzicharalampous C,Bai D,Abu-Soud HM

更新日期：2019-08-01 00:00:00

abstract：:The coordination structures of various species in the copper(II)-L-histidine (1:2) system in aqueous solution have been deduced by investigating the pH dependence of the electronic and circular dichroism spectra. The contribution to the spectra of the glycine-like and histamine-like binding modes of L-histidine has be...

journal_title：Journal of inorganic biochemistry

authors： Casella L,Gullotti M

更新日期：1983-02-01 00:00:00

abstract：:Xyloglucan is degraded by a mixture of copper(II), hydrogen peroxide and ascorbate. In the presence of ascorbate and/or hydrogen peroxide, copper(II) species were rapidly reduced to copper(I), which react with hydrogen peroxide. Spin-trapping experiments showed that hydroxyl radicals formed and attacked xyloglucan cau...

journal_title：Journal of inorganic biochemistry

authors： Tabbì G,Fry SC,Bonomo RP

更新日期：2001-04-01 00:00:00

abstract：:Bis(picolinato)oxovanadium(IV) [VO(pic)2] is one of the most potent insulin-mimetic vanadium complexes. To probe coordination structural changes of this complex in vivo and provide insights into the origin of its high potency, an electron spin-echo envelope modulation (ESEEM) study was performed on organs (kidney, liv...

journal_title：Journal of inorganic biochemistry

authors： Fukui K,Fujisawa Y,OhyaNishiguchi H,Kamada H,Sakurai H

更新日期：1999-11-01 00:00:00

abstract：:Composites of beta-chitin with calcium carbonate polymorphs were prepared by precipitation of the mineral into a chitin scaffold by means of a double diffusion system. The beta-chitin was obtained from the pen of the Loligo sp. squid. The three main polymorphs of calcium carbonate: aragonite, calcite and vaterite, wer...

journal_title：Journal of inorganic biochemistry

authors： Falini G,Fermani S,Ripamonti A

更新日期：2002-08-30 00:00:00

abstract：:Triapine, the most prominent anticancer drug candidate from the substance class of thiosemicarbazones, was investigated in >30 clinical phase I and II studies. However, the results were rather disappointing against solid tumors, which can be explained (at least partially) due to inefficient delivery to the tumor site....

journal_title：Journal of inorganic biochemistry

authors： Kallus S,Uhlik L,van Schoonhoven S,Pelivan K,Berger W,Enyedy ÉA,Hofmann T,Heffeter P,Kowol CR,Keppler BK

更新日期：2019-01-01 00:00:00

abstract：:Glutaredoxins (Grxs) are ubiquitous thioltransferases and members of the thioredoxin (Trx) fold superfamily. They have multiple functions in cells including oxidative stress responses and cell signaling. A novel glutaredoxin from buckwheat (rbGrx) with higher catalytic activity was identified, cloned, and purified. Th...

journal_title：Journal of inorganic biochemistry

authors： Zhang X,Wang W,Li C,Zhao Y,Yuan H,Tan X,Wu L,Wang Z,Wang H

更新日期：2017-08-01 00:00:00

abstract：:Hexacyanochromate ion, (Cr(CN)6)3-, was applied to ribonuclease T1 (RNase T1), which specifically cleaves RNA chains at guanylic acid residues. From kinetic studies, this anion was shown to bind to the active site of RNase T1 as a competitive inhibitor. Therefore, the line broadening effect of NMR resonances due to bi...

journal_title：Journal of inorganic biochemistry

authors： Inagaki F,Shimada I

更新日期：1986-10-01 00:00:00

abstract：:Four water soluble complexes of the type [M(bpy)(a-x)]NO3, where M is Pd(II) or Pt(II), bpy is 2,2-bipyridine, and a-x is anion of 2-pyridinecarboxylic acid or 2-pyrazinecarboxylic acid, have been found to bind calf thymus DNA, possibly through hydrogen binding. [M(bpy)(2-py)]NO3 complexes (2-py is an anion of 2-pyrid...

journal_title：Journal of inorganic biochemistry

authors： Mansuri-Torshizi H,Srivastava TS,Chavan SJ,Chitnis MP

更新日期：1992-10-01 00:00:00

abstract：:Type 2 diabetes mellitus has been associated with obesity, metabolic syndrome, cardiovascular diseases and cancer. Attempts have been made for early diagnosis and finding effective drugs to prevent severe consequences and ameliorate the symptoms of this disorder. In this work, the pharmacological properties of VO(dmpp...

journal_title：Journal of inorganic biochemistry

authors： Metelo AM,Pérez-Carro R,Castro MM,López-Larrubia P

更新日期：2012-10-01 00:00:00

abstract：:Human metallothionein-3 (hMT3), also named as human neuronal growth inhibitory factor (hGIF), can inhibit the outgrowth of embryonic cortical neurons in the presence of brain extracts. In order to systematically study the structure-property-reactivity-function relationship of hGIF, our laboratory designed a series of ...

journal_title：Journal of inorganic biochemistry

authors： Ding ZC,Zheng Q,Cai B,Ni FY,Yu WH,Teng XC,Gao Y,Liu F,Chen D,Wang Y,Wu HM,Sun HZ,Zhang MJ,Tan XS,Huang ZX

更新日期：2008-11-01 00:00:00

abstract：:In this paper we present the studies on coordination abilities of two short-chain analogues of somatostatin with free N-terminal and protected amino group towards copper (II) ions. The octreotide is the most popular analogue of the somatostatin (peptide hormone) used in medicine. Somatostatin analogues are used in dia...

journal_title：Journal of inorganic biochemistry

authors： Marciniak A,Cebrat M,Czyżnikowska Ż,Brasuń J

更新日期：2012-12-01 00:00:00

abstract：:Vanadium has well-documented blood-glucose-lowering properties both in vitro and in vivo. The design of new oxovanadium(IV) coordination compounds, intended for use as insulin-enhancing agents in the treatment of diabetes mellitus, can potentially benefit from a synergistic approach, in which the whole complex has mor...

journal_title：Journal of inorganic biochemistry

authors： Woo LC,Yuen VG,Thompson KH,McNeill JH,Orvig C

更新日期：1999-09-30 00:00:00

abstract：:HIF prolyl-4-hydroxylase 2 (PHD2) is a non-heme Fe, 2-oxoglutarate (2OG) dependent dioxygenase that regulates the hypoxia inducible transcription factor (HIF) by hydroxylating two conserved prolyl residues in N-terminal oxygen degradation domain (NODD) and C-terminal oxygen degradation domain (CODD) of HIF-1α. Prior s...

journal_title：Journal of inorganic biochemistry

authors： Pektas S,Knapp MJ

更新日期：2013-09-01 00:00:00

abstract：:Selenium in the form of selenocysteine plays an essential role in a number of proteins, but its role in non-enzymatic biochemistry is also important. In this short review we discuss the interactions between inorganic selenium, arsenic and mercury under physiological conditions, especially in the presence of glutathion...

journal_title：Journal of inorganic biochemistry

authors： Prince RC,Gailer J,Gunson DE,Turner RJ,George GN,Pickering IJ

更新日期：2007-11-01 00:00:00

abstract：:The technique of comparative genomic hybridisation (CGH) has until recently been used to screen for common genomic abnormalities in fresh tumour material; it has identified previously unrecognised regions of amplification associated with poor prognosis subtypes of breast cancer and lymphoma. Our group has applied this...

journal_title：Journal of inorganic biochemistry

authors： Hiorns LR,Seckl MJ,Paradinas F,Sharp SY,Skelton LA,Brunstrom G,Newlands ES,Kelland LR,Leyland-Jones B

更新日期：1999-10-01 00:00:00

abstract：:Coordination properties toward Fe(III) and Al(III) of a mixed bisphosphonate-hydroxypyridinonate ligand are presented. Potentiometric, spectrophotometric and NMR results allowed to conclude that Fe(III) and Al(III) coordination takes place on the pyridinone moiety. The high steric hindrance prevents the possibility of...

journal_title：Journal of inorganic biochemistry

authors： Crisponi G,Nurchi VM,Pivetta T,Gałezowska J,Gumienna-Kontecka E,Bailly T,Burgada R,Kozłowski H

更新日期：2008-07-01 00:00:00

abstract：:Tree laccase, a multi-copper oxidase, has been studied as a copper donor in conjunction with the demetalated forms of three blue copper proteins. Copper transfer could be observed under reducing conditions in the absence of air. Only about 10% of the total copper in laccase could be transferred regardless of the amoun...

journal_title：Journal of inorganic biochemistry

authors： Meadows KA,Morie-Bebel MM,McMillin DR

更新日期：1991-03-01 00:00:00

abstract：:Iron is frequently a growth-limiting nutrient due to its propensity to interact with oxygen to form insoluble precipitates and, therefore, biological systems have evolved specialized uptake mechanisms to obtain this essential nutrient. Many pathogenic bacteria are capable of obtaining stringently sequestered iron from...

journal_title：Journal of inorganic biochemistry

authors： Beasley FC,Heinrichs DE

更新日期：2010-03-01 00:00:00