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Siderophore-mediated iron acquisition in the staphylococci.

Abstract：

:Iron is frequently a growth-limiting nutrient due to its propensity to interact with oxygen to form insoluble precipitates and, therefore, biological systems have evolved specialized uptake mechanisms to obtain this essential nutrient. Many pathogenic bacteria are capable of obtaining stringently sequestered iron from animal hosts by one or both of the following mechanisms: extraction of heme from host erythrocyte and serum hemoproteins, or through the use of high affinity, iron-scavenging molecules termed siderophores. This review summarizes our current knowledge of siderophore-mediated iron acquisition systems in the genus Staphylococcus.

journal_name

J Inorg Biochem

journal_title

Journal of inorganic biochemistry

authors

Beasley FC,Heinrichs DE

doi

10.1016/j.jinorgbio.2009.09.011

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

282-8

issue

3

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(09)00230-X

journal_volume

104

pub_type

杂志文章,评审

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