Cytochrome c oxidase, ligands and electrons.

abstract：:Subcellular fractions were prepared by differential centrifugation from heart and liver of a lamb labeled with 75Se-selenite. Crude fractions of nuclei, mitochondria, and microsomes from both tissues were solubilized with sodium dodecyl sulfate and chromatographed on columns of sephacryl S-200. A low molecular weight ...

journal_title：Journal of inorganic biochemistry

authors： Beilstein MA,Tripp MJ,Whanger PD

更新日期：1981-12-01 00:00:00

abstract：:A series of new 3d metal complexes with 5-chloro-quinolin-8-ol (ClQ), [Mn(ClQ)2] (1), [Fe(ClQ)3] (2), [Co(ClQ)2(H2O)2] (3), [Ni(ClQ)2(H2O)2] (4), [Cu(ClQ)2] (5), [Zn(ClQ)2(H2O)2] (6), [Mn(ClQ)3]·DMF (7) and [Co(ClQ)3]·DMF·(EtOH)0.35 (8) (DMF=N,N-dimethylformamide), has been synthesized and characterized by elemental a...

journal_title：Journal of inorganic biochemistry

authors： Potočňák I,Vranec P,Farkasová V,Sabolová D,Vataščinová M,Kudláčová J,Radojević ID,Čomić LR,Markovic BS,Volarevic V,Arsenijevic N,Trifunović SR

更新日期：2016-01-01 00:00:00

abstract：:We prepared and characterized new iridium(III) complexes: [Ir(NC)2(MPPIP)](PF6) (N-C = 2-phenylpyridine 1; benzo[h]quinolone 2; 1-phenylisoquinolone, 3, MPPIP = 2-(4-(4'-methylpiperazin-yl)phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline). MTT (MTT = 3-(4,5-dimethylthiazole-2-yl)-2,5-biphenyl tetrazolium bromide) method ...

journal_title：Journal of inorganic biochemistry

authors： Gu Y,Wen H,Bai L,Zhou Y,Zhang H,Tian L,Zhang Y,Hao J,Liu Y

更新日期：2020-11-01 00:00:00

abstract：:Three novel copper(II) compounds of formulas {[Cu(Phen)(Ala)]·NO3·H2O}n (1), {[Cu(Phen)(Ala)]·NO3}n (2) and [Cu(Ala)2]n (3) have been synthesized and determined by X-ray diffraction. 1 and 2 are shown in one dimensional long-chain chiral structures, and 3 is a two dimensional checkerboard-type structure. Both 1 and 2 ...

journal_title：Journal of inorganic biochemistry

authors： Zhang WC,Tang X,Lu X

更新日期：2016-03-01 00:00:00

abstract：:The entire polypeptide of hyperthermophilic Pyrococcus furiosus rubredoxin was synthesized in order to specifically probe structural determinants of protein thermostability. The uv-visible, circular dichroic, electron paramagnetic, and nuclear magnetic resonance spectra, and electrochemical properties, of the native a...

journal_title：Journal of inorganic biochemistry

authors： Christen R,Jancic T,Zhou ZH,Adams MW,Tomich JM,Smith ET

更新日期：1997-01-01 00:00:00

abstract：:The interaction of Co(III) and Co(II) cobalamin (Cbl) and cobinamide (Cbi) with thiocyanate was examined with UV-vis and EPR spectra. S/N-linkage isomerism was explored on Co(III) and Co(II) Cbl and Cbi models using density functional theory (DFT; BP86, B3LYP). Performed calculations suggest the prevalence of isothioc...

journal_title：Journal of inorganic biochemistry

authors： Dereven'kov IA,Salnikov DS,Makarov SV,Surducan M,Silaghi-Dumitrescu R,Boss GR

更新日期：2013-08-01 00:00:00

abstract：:We have expressed and purified metal-resistance and metal regulatory proteins from the bacterial determinants of resistance to heavy metals and utilised these in the development of biosensors for heavy metals. Both the metallothionein from the cyanobacterium Synechococcus PCC 7942 and the MerR regulatory protein from ...

journal_title：Journal of inorganic biochemistry

authors： Bontidean I,Lloyd JR,Hobman JL,Wilson JR,Csöregi E,Mattiasson B,Brown NL

更新日期：2000-04-01 00:00:00

abstract：:This study performed in vitro and in vivo biological assays of the ruthenium (II) compound ct-[RuCl(CO)(dppb)(bipy)]PF6 (where, dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2'-bipyridine). The cytotoxic activity of this compound was evaluated against different tumor cell lines (HeLa, human cervical adenocarcinoma;...

journal_title：Journal of inorganic biochemistry

authors： Carnizello AP,Barbosa MI,Martins M,Ferreira NH,Oliveira PF,Magalhães GM,Batista AA,Tavares DC

更新日期：2016-11-01 00:00:00

abstract：:The efficiency of [Cu(2,2'-bipyridine)2(NO3)]NO3, [Cu(2,2'-dipyridylamine)2(NO3)2], and [Cu(dipicolylamine)2(NO3)2] complexes (complex 1, 2 and 3, respectively) in oxidative DNA cleavage was examined by electrophoresis and linear dichroism (LD). Among the three Cu complexes, complex 1 showed the highest efficiency in ...

journal_title：Journal of inorganic biochemistry

authors： Kwon JH,Park HJ,Chitrapriya N,Cho TS,Kim S,Kim J,Hwang IH,Kim C,Kim SK

更新日期：2014-02-01 00:00:00

abstract：:The interaction of V(IV)O-salts as well as of a few V(IV)O(carrier)n complexes with human serum transferrin (hTF) is studied focusing on the determination of the nature and stoichiometry of the binding of V(IV)O(2+) to hTF, as well as whether the conformation of hTF upon binding to V(IV)O(2+) or to its complexes is ch...

journal_title：Journal of inorganic biochemistry

authors： Mehtab S,Gonçalves G,Roy S,Tomaz AI,Santos-Silva T,Santos MF,Romão MJ,Jakusch T,Kiss T,Pessoa JC

更新日期：2013-04-01 00:00:00

abstract：:The CYP121 gene from the pathogenic bacterium Mycobacterium tuberculosis has been cloned and expressed in Escherichia coli, and the protein purified to homogeneity by ion exchange and hydrophobic interaction chromatography. The CYP121 gene encodes a cytochrome P450 enzyme (CYP121) that displays typical electronic abso...

journal_title：Journal of inorganic biochemistry

authors： McLean KJ,Cheesman MR,Rivers SL,Richmond A,Leys D,Chapman SK,Reid GA,Price NC,Kelly SM,Clarkson J,Smith WE,Munro AW

更新日期：2002-09-20 00:00:00

abstract：:Ruthenium complexes hold a great potential in chemotherapy as an alternative to the classical platinum based drugs. The organometallic compounds studied in the present work were previously found to exhibit important anticancer activities. Here we have investigated the binding of three ruthenium compounds, namely [Ru(η...

journal_title：Journal of inorganic biochemistry

authors： Morais TS,Santos FC,Corte-Real L,Garcia MH

更新日期：2013-12-01 00:00:00

abstract：:The effect of inositol hexakisphosphate (IHP) on the spectroscopic (EPR and absorbance) properties of the nitric oxide derivative of ferrous naturally glycated human hemoglobin HbA1c (HbA1cNO) has been investigated quantitatively. The results obtained show that 1) both in the absence and presence of IHP, the EPR and a...

journal_title：Journal of inorganic biochemistry

authors： Ascenzi P,Desideri A,Amiconi G,Bertollini A,Bolognesi M,Castagnola M,Coletta M,Brunori M

更新日期：1988-09-01 00:00:00

abstract：:Seven ferrocenyl naphthalene diimide (FND) ligands were synthesized. Each had a higher affinity for tetraplex DNA than for either single- or double-stranded DNA. The FND binding affinities were >105M-1 in 0.10M AcOH-AcONa or AcOH-AcOK (pH5.5) containing 0.10M NaCl or KCl. The FNDs with the highest binding affinities f...

journal_title：Journal of inorganic biochemistry

authors： Sato S,Takenaka S

更新日期：2017-02-01 00:00:00

abstract：:The discovery of new metal-selective complexing agents may be facilitated by applying an in vitro selection strategy. Such a strategy was recently devised to identify and enrich populations of bacteriophage that rely on Mg(II)-, Zn(II)-, or Au(III)-selective stabilization for survival in the presence of denaturing ure...

journal_title：Journal of inorganic biochemistry

authors： Whang T,Daly B,Yin J

更新日期：1996-07-01 00:00:00

abstract：:Lactoferrin (Lf) is a mammalian iron binding protein present in external secretions and in polymorphonuclear leukocytes. Its role in host defense mechanisms related to the non-immune defense system has been definitively established. Lf has two identical iron-binding sites, far from each other (44.3 A) and magnetically...

journal_title：Journal of inorganic biochemistry

authors： Fasano M,Fanali G,Polticelli F,Ascenzi P,Antonini G

更新日期：2004-08-01 00:00:00

abstract：:Copper(II) and zinc(II) complexes of the peptides Ac-HisValHis-NH2 and Ac-HisValGlyAsp-NH2 related to the active site of the enzyme CuZnSOD were studied by potentiometric and spectroscopic (UV-Vis, CD and EPR) techniques. The results reveal that both ligands have effective metal binding sites, but the tripeptide is a ...

journal_title：Journal of inorganic biochemistry

authors： Bóka B,Myari A,Sóvágó I,Hadjiliadis N

更新日期：2004-01-01 00:00:00

abstract：:The 1,7-diacetate-4,10-diacetamide substituted 1,4,7,10-tetraazacyclododecane structural unit is common to several responsive Magnetic Resonance Imaging (MRI) contrast agents (CAs). While some of these complexes (agents capable of sensing fluctuations in Zn2+, Ca2+ etc. ions) have already been tested in vivo, the deta...

journal_title：Journal of inorganic biochemistry

authors： Tircsó G,Tircsóné Benyó E,Garda Z,Singh J,Trokowski R,Brücher E,Sherry AD,Tóth É,Kovács Z

更新日期：2020-05-01 00:00:00

abstract：:Anhydrotetracycline (AHTC) is the major toxic decomposition product of the antibiotic tetracycline. The complexation of AHTC to Mg(II), Al(III), and Fe(III) was studied in aqueous medium using absorption and circular dichroism measurements. The study of the Mg(II)-AHTC interactions at pH 7 indicated the formation of t...

journal_title：Journal of inorganic biochemistry

authors： Machado FC,Demicheli C,Garnier-Suillerot A,Beraldo H

更新日期：1995-11-15 00:00:00

abstract：:Classical molecular dynamic simulations and density functional theory are used to unveil the interaction of aluminum with various phosphorylated derivatives of the fragment KSPVPKSPVEEKG (NF13), a major multiphosphorylation domain of human neurofilament medium (NFM). Our calculations reveal the rich coordination chemi...

journal_title：Journal of inorganic biochemistry

authors： Grande-Aztatzi R,Formoso E,Mujika JI,de Sancho D,Lopez X

更新日期：2020-09-01 00:00:00

abstract：:Preparation of metal/protein hybrids is growing into important topics in the field of bioinorganic chemistry. X-ray crystal structure analyses of them provide direct information on unique interactions of metal cations or metal cofactors to understand and design enzymatic functions. In this mini review, the authors foc...

journal_title：Journal of inorganic biochemistry

authors： Ueno T,Yokoi N,Abe S,Watanabe Y

更新日期：2007-11-01 00:00:00

abstract：:A series of hybrid quantum mechanical/molecular mechanical (QM/MM) calculations was performed on models of a DNA duplex with artificial silver(I)-mediated imidazole base pairs. The optimized structures were compared to the original experimental NMR structure (Nat. Chem. 2 (2010) 229-234). The metal⋯metal distances are...

journal_title：Journal of inorganic biochemistry

authors： Kumbhar S,Johannsen S,Sigel RK,Waller MP,Müller J

更新日期：2013-10-01 00:00:00

abstract：:Lathyrus cicera copper amine oxidase (LCAO) rapidly formed the typical Cu(I)-TPQ semiquinone UV-visible spectrum, identical to that formed by other substrates, upon O(2) exhaustion by turnover with excess tryptamine. A new band at 630 nm formed more slowly, with intensity dependent on aldehyde and H(2)O(2) concentrati...

journal_title：Journal of inorganic biochemistry

authors： Pietrangeli P,Bellelli A,Fattibene P,Mondovì B,Morpurgo L

更新日期：2012-04-01 00:00:00

abstract：:The effect of the Cu(II)-mitoxantrone complex on the DNA synthesis of HL-60 human leukemia cells has been studied by the technique of isotopic liquid scintillation. The results indicated that the complex shows a stronger ability to inhibit DNA synthesis of the tumor cells, and thus it may become a better antitumor dru...

journal_title：Journal of inorganic biochemistry

authors： Yang P,Wang H,Gao F,Yang B

更新日期：1996-05-01 00:00:00

abstract：:The ligand behavior of di-2-pyridylketone 2-aminobenzoylhydrazone (Hdpa), and phenyl(2-pyridyl)ketone 2-aminobenzoylhydrazone (Hdba) towards organotin derivatives was investigated. The synthesis and the IR and 119Sn NMR spectroscopic characterization of the compounds is reported, together with the X-ray crystal struct...

journal_title：Journal of inorganic biochemistry

authors： Ianelli S,Mazza P,Orcesi M,Pelizzi C,Pelizzi G,Zani F

更新日期：1995-11-01 00:00:00

abstract：:The substitution of tetradentate bispidine ligands with rhodamine and cyanine dye molecules, coupled to an amine donor, forming an amide as potential fifth donor, is described. Bispidines are known to lead to very stable Cu(II) complexes, and the coordination to Cu(II) was expected to efficiently quench the fluorescen...

journal_title：Journal of inorganic biochemistry

authors： Brox D,Comba P,Herten DP,Kimmle E,Morgen M,Rühl CL,Rybina A,Stephan H,Storch G,Wadepohl H

更新日期：2015-07-01 00:00:00

abstract：:Transferrin, the human iron transport protein, binds Ti(IV) even more tightly than it binds Fe(III). However, the fate of titanium bound to transferrin is not well understood. Here we present results which address the fate of titanium once bound to transferrin. We have determined the redox potentials for a series of T...

journal_title：Journal of inorganic biochemistry

authors： Parker Siburt CJ,Lin EM,Brandt SJ,Tinoco AD,Valentine AM,Crumbliss AL

更新日期：2010-09-01 00:00:00

abstract：:The synthesis, physico-chemical characterization and cytotoxicity against five human tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of three new cobalt(II) coordination compounds are reported (i.e. Co(HL1)Cl (1), Co(HL2)Cl (2) and [Co(HL3)Cl]0.0.5 (CH3)2CHOH (3)). H2L2 (2-{[[2-hydroxy-3-(1-naphthyloxy)prop...

journal_title：Journal of inorganic biochemistry

authors： Morcelli SR,Bull ÉS,Terra WS,Moreira RO,Borges FV,Kanashiro MM,Bortoluzzi AJ,Maciel LL,de A Almeida JC,Júnior AH,Fernandes C

更新日期：2016-08-01 00:00:00

abstract：:Complexes of cadmium(II) derivatives with adenine from water or by simulation of physiological conditions are obtained. The complexes have been studied by spectroscopic, conductometric, 1H-NMR, and by TG and DSC measurements. Possible coordination modes of the ligand are proposed. ...

journal_title：Journal of inorganic biochemistry

authors： Fontana A,Maggio F,Pizzino T

更新日期：1987-02-01 00:00:00

abstract：:Quinoline antimalarial drugs such as chloroquine and related compounds are believed to act by targeting ferriprotoporphyrin IX (Fe(III)PPIX) in the form of hematin (H(2)O/HO-Fe(III)PPIX), its mu-oxo dimer ([Fe(III)PPIX](2)O) or crystalline beta-hematin ([Fe(III)PPIX](2)) in the malaria parasite. Fe(III)PPIX is formed ...

journal_title：Journal of inorganic biochemistry

authors： Egan TJ

更新日期：2006-05-01 00:00:00