Strong poison revisited.

Abstract:

:Selenium in the form of selenocysteine plays an essential role in a number of proteins, but its role in non-enzymatic biochemistry is also important. In this short review we discuss the interactions between inorganic selenium, arsenic and mercury under physiological conditions, especially in the presence of glutathione. This chemistry is obviously important in making the arsenic and mercury unavailable for more toxic interactions, but in the process it suggests that a side-effect of chronic arsenic and/or mercury exposure is likely to be functional selenium deficiency.

journal_name

J Inorg Biochem

authors

Prince RC,Gailer J,Gunson DE,Turner RJ,George GN,Pickering IJ

doi

10.1016/j.jinorgbio.2007.06.008

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

1891-3

issue

11-12

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(07)00133-X

journal_volume

101

pub_type

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