Reprint of "Anticancer activity of hydroxy- and sulfonamide-azobenzene platinum(II) complexes in cisplatin-resistant ovarian cancer cells".

abstract：:Interaction of Delta,Delta- and Lambda,Lambda-bis-Ru(II) complexes with native DNA was investigated by isotropic absorption and polarized spectroscopy including circular and linear dichroism (CD and LD). Despite the steric hindrance originating from its four bulky phenanthroline ligands at both ends of the molecule, t...

journal_title：Journal of inorganic biochemistry

authors： Jang YJ,Kwon BH,Choi BH,Bae CH,Seo MS,Nam W,Kim SK

更新日期：2008-10-01 00:00:00

abstract：:Quantitative characterization of metalloproteins at molecular and atomic levels generally requires tens of milligrams of highly purified samples, a situation frequently challenged by problems in generating unmodified native forms. A variety of affinity tags, such as the popular poly-histidine tag, have been developed ...

journal_title：Journal of inorganic biochemistry

authors： Wijekoon CJK,Ukuwela AA,Wedd AG,Xiao Z

更新日期：2016-09-01 00:00:00

abstract：:Coordination properties toward Fe(III) and Al(III) of a mixed bisphosphonate-hydroxypyridinonate ligand are presented. Potentiometric, spectrophotometric and NMR results allowed to conclude that Fe(III) and Al(III) coordination takes place on the pyridinone moiety. The high steric hindrance prevents the possibility of...

journal_title：Journal of inorganic biochemistry

authors： Crisponi G,Nurchi VM,Pivetta T,Gałezowska J,Gumienna-Kontecka E,Bailly T,Burgada R,Kozłowski H

更新日期：2008-07-01 00:00:00

abstract：:Xyloglucan is degraded by a mixture of copper(II), hydrogen peroxide and ascorbate. In the presence of ascorbate and/or hydrogen peroxide, copper(II) species were rapidly reduced to copper(I), which react with hydrogen peroxide. Spin-trapping experiments showed that hydroxyl radicals formed and attacked xyloglucan cau...

journal_title：Journal of inorganic biochemistry

authors： Tabbì G,Fry SC,Bonomo RP

更新日期：2001-04-01 00:00:00

abstract：:Alpha-glucosidase is considered to be an important target for the treatment of noninsulin-dependent diabetes. In this work, the inhibitory effects of polyoxometalates (POMs) affected by three different factors (heteroatom, transition metal substitution element and vanadium substitution number) on α-glucosidase were st...

journal_title：Journal of inorganic biochemistry

authors： Chi G,Wang L,Chen B,Li J,Hu J,Liu S,Zhao M,Ding X,Li Y

更新日期：2019-10-01 00:00:00

abstract：:To construct the model of metallohydrolase, two inclusion complexes [MLCl2(β-CD)] (1, M=Zn(II); 2, M=Cu(II); L=N,N'-bis(2-pyridylmethyl)amantadine; β-CD=β-cyclodextrin) were synthesized by mixing β-CDs with the pre-synthesized complexes G1, [ZnLCl2] and G2, [CuLCl2]. Structures of G1, G2, 1 and 2 were characterized by...

journal_title：Journal of inorganic biochemistry

authors： Zhou YH,Chen LQ,Tao J,Shen JL,Gong DY,Yun RR,Cheng Y

更新日期：2016-10-01 00:00:00

abstract：:Subcellular fractions were prepared by differential centrifugation from heart and liver of a lamb labeled with 75Se-selenite. Crude fractions of nuclei, mitochondria, and microsomes from both tissues were solubilized with sodium dodecyl sulfate and chromatographed on columns of sephacryl S-200. A low molecular weight ...

journal_title：Journal of inorganic biochemistry

authors： Beilstein MA,Tripp MJ,Whanger PD

更新日期：1981-12-01 00:00:00

abstract：:Aluminium (Al) has been measured in human breast tissue, and may be a contributory factor in breast cancer development. At the 10th Keele meeting, we reported that long-term exposure to Al could increase migratory properties of oestrogen-responsive MCF-7 human breast cancer cells suggesting a role for Al in the metast...

journal_title：Journal of inorganic biochemistry

authors： Bakir A,Darbre PD

更新日期：2015-11-01 00:00:00

abstract：:We have synthesised the complex [Pt(CH(3)SCH(2)CH(2)SCH(3))(5'-GMP-N7)(2)].6H(2)O (1), where 5'-GMP is 5'-guanosine monophosphate, and determined its X-ray crystal structure. Pt(II) adopts a square-planar geometry in which the bases are coordinated head-to-tail (HT) in the Delta configuration. The nucleotide conformat...

journal_title：Journal of inorganic biochemistry

authors： Djuran MI,Milinkovic SU,Habtemariam A,Parsons S,Sadler PJ

更新日期：2002-02-01 00:00:00

abstract：:Biological studies on [Fe(L)2](NO3).0.5H2O (1), [Fe(L)2][PF6] (2), [Co(L)2](NCS) (3), [Ni(HL)2]Cl2.3H2O (4) and Cu(L)(NO3) (5), where HL=C7H8N4S, pyridine-2-carbaldehyde thiosemicarbazone, have been carried out. The crystal structure of compound 3 has been solved. It consists of discrete monomeric cationic entities co...

journal_title：Journal of inorganic biochemistry

authors： García-Tojal J,García-Orad A,Díaz AA,Serra JL,Urtiaga MK,Arriortua MI,Rojo T

更新日期：2001-04-01 00:00:00

abstract：:Fourteen new complexes were obtained from Ln(III)(NO3)3∙n-H2O and the chromophores 2-(1H-benzo[d]imidazol-2-yl)-phenol (Bzp1) or 2-(5-methyl-1H-benzo[d]imidazol-2-yl)-phenol (Bzp2). The complete characterization allowed us to assign unequivocally the structures of all the complexes. The techniques used for this purpos...

journal_title：Journal of inorganic biochemistry

authors： Hernández-Morales A,Rivera JM,López-Monteon A,Lagunes-Castro S,Castillo-Blum S,Cureño-Hernández K,Flores-Parra A,Villaseñor-Granados O,Colorado-Peralta R

更新日期：2019-12-01 00:00:00

abstract：:Recent stopped-flow kinetics demonstrated the existence of an intermediate before the occurrence of the final product of the reaction of both iron-containing microperoxidase-8 (Fe(III)MP-8) and manganese-containing microperoxidase-8 (Mn(III)MP-8) with H(2)O(2). The intermediate was assigned to be (hydro)peroxo-iron. W...

journal_title：Journal of inorganic biochemistry

authors： Veeger C

更新日期：2002-07-25 00:00:00

abstract：:In this paper, antineoplastic activities of protein-conjugated silver sulfide nano-crystals with different shapes were described in detail. Transmission electron microscope analysis demonstrated that stable and well-disperse protein-conjugated silver sulfide nano-particles, nano-rods, and nano-wires could be prepared ...

journal_title：Journal of inorganic biochemistry

authors： Wang HJ,Yang L,Yang HY,Wang K,Yao WG,Jiang K,Huang XL,Zheng Z

更新日期：2010-01-01 00:00:00

abstract：:Complex formation between Cu(II) and human and bovine beta-casomorphin heptapeptides, Tyr-Pro-Phe-Val-Glu-Pro-Ile and Tyr-Pro-Phe-Pro-Gly-Pro-Ile, respectively, was investigated by pH potentiometry and spectroscopic (CD, EPR and electronic absorption) techniques. The results showed the critical impact of Pro residues ...

journal_title：Journal of inorganic biochemistry

authors： Chruścińska E,Olczak J,Zabrocki J,Dyba M,Micera G,Sanna D,Kozłowski H

更新日期：1998-02-01 00:00:00

abstract：:Calcium functions as a secondary messenger within the cytosols of eukaryotes. This serves as a reference point to evaluate three related questions:Exploration of these three interrelated questions indicates the importance of more sensitive techniques and of a refined concept of information transfer and transduction. 1...

journal_title：Journal of inorganic biochemistry

authors： Permyakov EA,Kretsinger RH

更新日期：2009-01-01 00:00:00

abstract：:It was shown that the treatment of a DNA fragment and a hepta-decanucleotide having a hairpin structure by Ru(2,2'-bipyridyl)3(3+) complex at 15 degrees C in 1 M NaCl for 10-60 min, and subsequent hydrolysis in 1 M piperidine at 95 degrees C led to the specific cleavage of the polynucleotide chain at guanosine residue...

journal_title：Journal of inorganic biochemistry

authors： Fedorova OS,Podust LM

更新日期：1988-11-01 00:00:00

abstract：:The cysteine proteases of the trypanosomatid parasitic protozoa have been validated as targets for chemotherapy of Chagas' disease and leishmaniasis. Metal complexes of gold, platinum, iridium, palladium, rhodium and osmium have been reported to have activity against a variety of trypanosomatids, but the molecular tar...

journal_title：Journal of inorganic biochemistry

authors： Fricker SP,Mosi RM,Cameron BR,Baird I,Zhu Y,Anastassov V,Cox J,Doyle PS,Hansell E,Lau G,Langille J,Olsen M,Qin L,Skerlj R,Wong RS,Santucci Z,McKerrow JH

更新日期：2008-10-01 00:00:00

abstract：:HtaA is a heme-binding protein that is part of the heme uptake system in Corynebacterium diphtheriae. HtaA contains two conserved regions (CR1 and CR2). It has been previously reported that both domains can bind heme; the CR2 domain binds hemoglobin more strongly than the CR1 domain. In this study, we report the bioph...

journal_title：Journal of inorganic biochemistry

authors： Uluisik RC,Akbas N,Lukat-Rodgers GS,Adrian SA,Allen CE,Schmitt MP,Rodgers KR,Dixon DW

更新日期：2017-02-01 00:00:00

abstract：:Bacteria have developed multiple resistance mechanisms against the most used antibiotics. In particular, zinc-dependent metallo-β-lactamase producing bacteria are a growing threat, and therapeutic options are limited. Zinc chelators have recently been investigated as metallo-β-lactamase inhibitors, as they are often a...

journal_title：Journal of inorganic biochemistry

authors： La Piana L,Viaggi V,Principe L,Di Bella S,Luzzaro F,Viale M,Bertola N,Vecchio G

更新日期：2021-02-01 00:00:00

abstract：:Positional isomers of mono-unsaturated 18:1-ACP have been used as substrates for stearoyl-acyl carrier protein delta9 desaturase to test whether a C-H bond abstraction from either the C-9 or C-10 position could lead to rearranged products diagnostic for the production of an allylic radical intermediate. The reconstitu...

journal_title：Journal of inorganic biochemistry

authors： Broadwater JA,Laundre BJ,Fox BG

更新日期：2000-01-15 00:00:00

abstract：:Human metallothionein-3 (hMT3), also named as human neuronal growth inhibitory factor (hGIF), can inhibit the outgrowth of embryonic cortical neurons in the presence of brain extracts. In order to systematically study the structure-property-reactivity-function relationship of hGIF, our laboratory designed a series of ...

journal_title：Journal of inorganic biochemistry

authors： Ding ZC,Zheng Q,Cai B,Ni FY,Yu WH,Teng XC,Gao Y,Liu F,Chen D,Wang Y,Wu HM,Sun HZ,Zhang MJ,Tan XS,Huang ZX

更新日期：2008-11-01 00:00:00

abstract：:In heme peroxidases, a distal His residue plays an essential role in the initial two electron oxidation of resting state enzyme to compound I by hydrogen peroxide. A distal Arg residue assists in this process. The contributions of the charge, H-bonding capacity, size, and mobility of this Arg residue to Coprinus ciner...

journal_title：Journal of inorganic biochemistry

authors： Schiødt CB,Veitch NC,Welinder KG

更新日期：2007-02-01 00:00:00

abstract：:The metallodrug chloridotetrakis(ibuprofenato)diruthenium(II,III) ([Ru2(Ibp)4Cl] or RuIbpCl (1), Ibp=carboxylate anion derived from the non-steroidal anti-inflammatory drug ibuprofen) has shown promising results in vitro and in vivo, which point to its potential as an inhibitor of glioma tumour growth in vivo. In orde...

journal_title：Journal of inorganic biochemistry

authors： Hanif-Ur-Rehman,Freitas TE,Gomes RN,Colquhoun A,de Oliveira Silva D

更新日期：2016-12-01 00:00:00

abstract：:Recent studies of the reaction mechanism of the molybdenum-containing enzyme xanthine oxidase are presented. The pH-dependence of both the steady-state and rapid reaction kinetics of the enzyme exhibits is bell-shaped, with pK(a)s for the acid and alkaline limbs of 6.6 and 7.4, respectively. These are assigned to ioni...

journal_title：Journal of inorganic biochemistry

authors： Choi EY,Stockert AL,Leimkühler S,Hille R

更新日期：2004-05-01 00:00:00

abstract：:Up-regulated expression of amyloid precursor protein (APP) occurs early in the cascade of events that leads to amyloid plaque formation in the human brain. APP gene up-regulation, mediated by activated NF-kappaB, is a response to stress from nM concentrations of aluminum ions, aluminum-disregulated iron ions, reactive...

journal_title：Journal of inorganic biochemistry

authors： Walton JR,Wang MX

更新日期：2009-11-01 00:00:00

abstract：:This work describes the synthesis and characterization of six new dinuclear platinum complexes having N,N'-di-(2-aminoethyl)-1,3-diamino-2-propanol, aryl substituted N-benzyl-1,4-butanediamines and N-benzyl-1,6-hexanediamines as ligands. They were prepared by the reaction of cis-[PtCl(2)(DMSO)(2)] (DMSO=dimethyl sulfo...

journal_title：Journal of inorganic biochemistry

authors： Cesar ET,de Almeida MV,Fontes AP,Pereira Maia EC,Garnier-Suillerot A,Rúbia Costa Couri M,de Castro Antunes Felício E

更新日期：2003-07-01 00:00:00

abstract：:The activity against human cancer cell lines including ovarian: A2780, A2780(cisR), cell up take, DNA-binding and nature of interaction with pBR322 plasmid DNA have been studied for four multinuclear complexes code named DH4Cl, DH5Cl, DH6Cl and DH7Cl, having the general formula: [[trans-PtCl(NH(3))(2)](2)mu-[trans-Pd(...

journal_title：Journal of inorganic biochemistry

authors： Daghriri H,Huq F,Beale P

更新日期：2004-11-01 00:00:00

abstract：:The reaction of hydrogen peroxide and certain aromatic aldehydes with cytochrome P450BM3-F87G results in the covalent modification of the heme cofactor of this monooxygenase. Analysis of the resulting heme by electronic absorption spectrophotometry indicates that the reaction in the BM3 isoform is analogous to that in...

journal_title：Journal of inorganic biochemistry

authors： Raner GM,Hatchell AJ,Morton PE,Ballou DP,Coon MJ

更新日期：2000-08-31 00:00:00

abstract：:The study of modified synthetic procedure of water soluble morin-5'-sulfonic acid sodium salt (NaMSA) involving less aggressive chemicals and carried out at mild conditions was described. The NaMSA salt is a convenient source of anionic morin-5'-sulfonic ligand (MSA) in ion exchange reactions. The coordination ability...

journal_title：Journal of inorganic biochemistry

authors： Pieniążek E,Kalembkiewicz J,Dranka M,Woźnicka E

更新日期：2014-12-01 00:00:00

abstract：:A combination of magnetic circular dichroism (MCD), electronic absorption spectroscopy and time-dependent density functional theory (TD-DFT) calculations has been used to investigate the electronic structure of azulene-fused pi-expanded porphyrins based primarily on the spectral properties of absorption bands in the n...

journal_title：Journal of inorganic biochemistry

authors： Nakai K,Kurotobi K,Osuka A,Uchiyama M,Kobayashi N

更新日期：2008-03-01 00:00:00