Abstract:
:We have isolated the Drosophila melanogaster locus coding for L-glutamate dehydrogenase (EC 1.4.1.3) by virtue of its similarity to the corresponding human gene. There is only one copy of this gene in the fruit fly genome, located on the right arm of chromosome 3 (95D1-4). The transcript includes at least one large intron and matures to a approximately 2.4-kb-long polyadenylated RNA whose expression is under developmental control.
journal_name
Biochem Genetjournal_title
Biochemical geneticsauthors
Papadopoulou D,Louis Csubject
Has Abstractpub_date
1990-08-01 00:00:00pages
337-46issue
7-8eissn
0006-2928issn
1573-4927journal_volume
28pub_type
杂志文章abstract::Electrophoretic variation of sorbitol dehydrogenase has been found in Mus musculus; the SDH-1 A phenotype migrates further toward the cathode under the conditions used than the SDH-1B phenotype. Mice with the SDH-1B phenotype have enzyme activity reduced to 25% of that found in mice with the SDH-1A phenotype, but no d...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00498928
更新日期:1983-08-01 00:00:00
abstract::The inducibility of alcohol dehydrogenase (ADH) has been recognized in different systems including maize, Drosophila, and mice. Our earlier results showed strain-specific ADH responses to chronic ethanol administration relative to matched littermate controls in mice. For this study we used two strains which showed "in...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485847
更新日期:1984-08-01 00:00:00
abstract::The allele, genotype, and haplotype frequencies among 837 Polish Holstein-Friesian cattle were determined at two regulatory indel polymorphisms of the PRNP gene. Allele frequencies at the 23 bp indel promoter polymorphism were 0.622 (del) and 0.378 (ins), with 0.613 and 0.387 in sires and 0.633 and 0.366 in dams. Alle...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-010-9408-2
更新日期:2011-06-01 00:00:00
abstract::Polysomes from 5.5-day and 6.5-day embryonic chick erythroid cells contain messenger RNA (mRNA) which can be translated into products in a cell-free protein-synthesizing system. The products of the cell-free system coelectrophoresed with carrier globin chains from the cells from which the polysomal pellet was isolated...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00483979
更新日期:1977-10-01 00:00:00
abstract::The extent of naturally occurring variations of enzyme locus expression was determined for three tissues (liver, muscle, and eye) in two species of sunfish (Centrarchidae), the green sunfish (Lepomis cyanellus) and the redear sunfish (L. microlophus). The genetic basis for species differences in tissue enzyme specific...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499484
更新日期:1984-10-01 00:00:00
abstract::Considering that the genetically modified soybean lectin gene is affected by the gene type, to improve the stability of the genetically modified soybean lectin gene, a method based on fluorescence quantitative PCR to analyze the genetic characteristics of the genetically modified soybean lectin was proposed. The commo...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09998-3
更新日期:2020-09-26 00:00:00
abstract::Animal melanin has an important role in the formation of animal fur and skin, which is determined by its quantities, character, and distribution. To identify the effect of melanin on the formation of multi-colored Rex rabbits (Black, Chinchilla, Beaver, Protein cyan, Protein yellow, White), the structure of hair folli...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-019-09929-x
更新日期:2019-10-01 00:00:00
abstract::Differences in Zn-induced levels of hepatic metallothionein (MT) in inbred strains of the mouse are described. Three low-producing strains, C57 BL/6, C57BL/10, and NIH, are identified, while C3H and CBA display the highest levels of hepatic MT following Zn treatment. These interstrain differences affect not only the l...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02401801
更新日期:1989-04-01 00:00:00
abstract::The aryl hydrocarbon hydroxylase (Ah) locus that controls the induction of chemical carcinogen-metabolizing enzymes in mice has been found to be linked to a new restriction-fragment length polymorphism (RFLP). Only C57BL/6 and closely related inbred strains displayed a 7.6-kb HindIII restriction fragment, while all ot...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554549
更新日期:1987-06-01 00:00:00
abstract::Genetic diversity and genetic structure within and among ten populations of Stephania yunnanensis H. S. Lo and three populations of S. epigaea H. S. Lo from Yunnan province were evaluated by direct amplification of length polymorphism (DALP) markers. Five primer groups were screened, and a total of 287 DNA fragments w...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9146-x
更新日期:2008-04-01 00:00:00
abstract::This study aims to compare the expression of P2X receptor subtype mRNA in different arterial tissues of rats. After the rats were sacrificed, the internal carotid, pulmonary, thoracic aorta, mesenteric and caudal arteries were dissected out. Then, the P2X receptor mRNA expression in different blood vessels was detecte...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-020-09968-9
更新日期:2020-10-01 00:00:00
abstract::Among several autoimmune diseases, one of the main risk factors is the female gender, and much consideration has been given to the involvement of female hormones in their etiology. B-cell activating factor (BAFF) is a key factor in survival and maturation of B cells and is overexpressed in several autoimmune patients ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-016-9752-y
更新日期:2016-10-01 00:00:00
abstract::Cleavage patterns of mitochondrial DNAs (mtDNAs) by 15 restriction endonucleases were analyzed for 10 swamp and 13 river types of domestic water buffaloes. Digestions with nine enzymes exhibited polymorphisms giving two or three kinds of cleavage patterns. Five mtDNA types were identified, three types in the swamp buf...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00554726
更新日期:1995-06-01 00:00:00
abstract::The genetic linkage relationships of the human glycosphingolipid beta-galactosidases were determined using human--mouse somatic cell hybrids. A new method was devised for the estimation of human galactosylceramide, lactosylceramide, and GMI-ganglioside beta-galactosidase activities in the presence of their mouse count...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484498
更新日期:1977-12-01 00:00:00
abstract::Three serum transferrin phenotypes of Praomys (Mastomys) natalensis, and African rodent having a high incidence of many varieties of spontaneous neoplasms, were detected by electrophoresis and autoradiography. On electrophoresis, transferrin of Trf-K was found to be a protein that migrates slowly toward the cathode, w...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00485334
更新日期:1976-10-01 00:00:00
abstract::Mitochondrial DNA (mtDNA) from two breeds of cattle, viz., [Hariana (Bos indicus), Holstein (Bos taurus)] and Indian water buffalo (Bubalis bubalus), was analyzed using 13 restriction endonucleases which recognized an average of about 40 six-base sites. Polymorphism among cattle was detected with six of these enzymes....
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02401421
更新日期:1990-08-01 00:00:00
abstract::Three distinct malathion carboxylesterase (MCE) phenotypes have been identified among strains of Lucilia cuprina. The high-activity phenotype shows 1.6- and 33-fold more MCE specific activity than the intermediate- and low-activity phenotypes, respectively. Flies with high MCE activity are 1000-fold more resistant to ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00566064
更新日期:1994-12-01 00:00:00
abstract::Studies on hybridization, inheritance, and population genetics of brown planthoppers that infest rice and weeds were undertaken using starch gel electrophoresis to determine whether the weed-infesting population represents a biological race or a species. F(1) and F(2) generations were produced by crosses between paren...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-009-9316-5
更新日期:2010-04-01 00:00:00
abstract::CCR5 is a seven-transmembrane G-protein-coupled receptor that binds the CC-chemokines including RANTES, eotaxin, MIP-1alpha and beta. CCR5 serves as an essential coreceptor for cell entry of R5 (macrophage-tropic, nonsyncytium-inducing) strains of HIV-1. To date, four deletions have been found in human and primate ccr...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:
更新日期:2005-06-01 00:00:00
abstract::UMPK 3 is a rare variant of the polymorphic enzyme of human red cells, uridine monophosphate kinase. This homozygote phenotype was detected among the Warao Indians of Venezuela. The UMPK 1 and UMPK 3 enzymes were partially purified following the method described by Tend et al. (1976). The biochemical and kinetic param...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484529
更新日期:1978-12-01 00:00:00
abstract::Scirpophaga incertulas, commonly referred to as yellow stem borer, is a predominant pest of rice causing serious losses in its yield. Genetic variation among populations of Scirpophaga incertulas collected from 28 hotspot locations in India was examined using the randomly amplified polymorphic DNA-polymerase chain rea...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1002797219182
更新日期:2001-02-01 00:00:00
abstract::We describe a simple method for locating tryptophanyl-tRNA synthetase (E.C. 6.1.1.2) on cellulose acetate gels (Cellogel) following electrophoresis. Employing electrophoretic conditions which result in the separation of mouse and human tryptophanyl-tRNA synthetase, we have analyzed extracts of a number of independentl...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484877
更新日期:1976-02-01 00:00:00
abstract::Skeletal muscle tissues from many species of salmonid fish are known to exhibit a set of three of five isozymes for A4-type lactate dehydrogenase (L-lactate: NAD oxidoreductase, E.C. 1.1.1.27), but the genetic basis for this isozyme system has not previously been assessed. This isozyme system was purified to homogenei...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00484099
更新日期:1977-08-01 00:00:00
abstract::Oral cavity cancer belongs to head-and-neck squamous cell carcinoma group. The purpose of the study was to assess the levels of certain proteins in a tumour and surgical margin in a group of patients with oral cavity cancer. The levels of DAPK1, MGMT, CDH1, SFRP1, SFRP2, RORA, TIMP3, p16, APC and RASSF1 proteins were ...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-017-9799-4
更新日期:2017-08-01 00:00:00
abstract::A mouse mutant with pyruvate kinase (PK) hyperactivity has been found in offspring of 1-ethyl-1-nitrosourea (ENU)-treated male mice. The activity alteration was detected in the blood and could also be found in the liver but not in the muscle, kidney, heart, spleen, lung, or brain. Heterozygous mice have erythrocyte PK...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00499635
更新日期:1984-12-01 00:00:00
abstract::Electrophoretic variation is described for malic enzyme (ME) for the first time in brook trout (Salvelinus fontinalis). Since the quaternary structure of ME was not clear from examination of banding patterns in brook trout alone, ME phenotypes in rainbow trout (Salmo gairdneri)X brook trout hybrids as wel as in esoci...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF00502121
更新日期:1979-08-01 00:00:00
abstract::A restriction map has been constructed for Anastrepha suspensa mitochondrial DNA. One HaeIII site was found to be polymorphic among individuals in highly inbred colonies and a feral population. Based on mapping information, the polymorphic site was determined to be in the ATPase 6 gene. Primers TK-J-3804 and C3-N-5460...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1019839102099
更新日期:2002-08-01 00:00:00
abstract::An Italian organophosphate-resistant strain of Culex pipiens (Lucca) was found to be polymorphic for elevated and nonelevated esterases. Selection for high esterase activity produced a strain homozygous for elevated esterases A2 and B2. Selection for low activity produced a strain homozygous for nonelevated esterases,...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/BF02426878
更新日期:1993-12-01 00:00:00
abstract::Markhors (Capra falconeri) are among the most endangered mammal species, and several conservation measures, including ex situ breeding, are implemented to prevent their extinction. We studied sequence diversity and differentiation of the first hypervariable segment of the mitochondrial DNA control region among C. f. h...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1007/s10528-008-9145-y
更新日期:2008-04-01 00:00:00
abstract::This study deals with the characterization of 10 populations of M. musculus from different geographical locations in India. The genetics of Indian wild mice has been completely obscure and this is the first report on allozyme variations in the natural population. We have used a set of 24 biochemical genetic markers to...
journal_title:Biochemical genetics
pub_type: 杂志文章
doi:10.1023/a:1018781026170
更新日期:1998-08-01 00:00:00