The missing link: chemokine receptors and tissue matrix breakdown in COPD.

Abstract:

:Chronic obstructive pulmonary disease (COPD) is a pulmonary inflammatory disease that is caused by cigarette smoke. The main characteristic of COPD is the continued inflammation caused by the sustained influx of macrophages and neutrophils into the lung. Recent studies have shed light on how these cells are attracted during acute and chronic inflammation of the lung. The factors involved might be both a biomarker and a therapeutic target in COPD.

journal_name

Trends Pharmacol Sci

authors

Smit JJ,Lukacs NW

doi

10.1016/j.tips.2006.09.003

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

555-7

issue

11

eissn

0165-6147

issn

1873-3735

pii

S0165-6147(06)00221-5

journal_volume

27

pub_type

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