Maryland's Special Populations Network. A model for cancer disparities research, education, and training.

abstract：BACKGROUND:Children diagnosed with medulloblastoma whose tumor involves the brain stem or has spread through the cerebrospinal fluid pathways to other areas of the brain or spinal cord have a poor prognosis despite therapy with surgery, craniospinal irradiation (CSI), and chemotherapy. Preradiation chemotherapy may imp...

journal_title：Cancer

authors： Mosijczuk AD,Nigro MA,Thomas PR,Burger PC,Krischer JP,Morantz RA,Kurdunowicz B,Mulne AF,Towbin RB,Freeman AI

更新日期：1993-11-01 00:00:00

abstract：:The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...

journal_title：Cancer

authors： Kyriazis AP,Yagoda A,Kereiakes JG,Kyriazis AA,Whitmore WF Jr

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:The role of myeloablative chemotherapy in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors (MB/ST-PNET) is controversial, in particular in patients who develop recurrent disease after craniospinal radiotherapy. METHODS:In this retrospective analysis, the authors in...

journal_title：Cancer

authors： Butturini AM,Jacob M,Aguajo J,Vander-Walde NA,Villablanca J,Jubran R,Erdreich-Epstein A,Marachelian A,Dhall G,Finlay JL

更新日期：2009-07-01 00:00:00

abstract：:The authors administered high-dose chemotherapy with cyclophosphamide, BCNU (carmustine) and VP-16 (etoposide) plus autologous bone marrow transplantation (ABMT) to 22 adult patients with relapsed acute leukemia in second or subsequent remission. The marrow was not treated ex vivo. The long-term, disease-free survival...

journal_title：Cancer

authors： Spinolo JA,Dicke KA,Horwitz LJ,Jagannath S,McCredie K,Estey E,Kantarjian H,Zander AR,Keating M,Spitzer G

更新日期：1990-08-15 00:00:00

abstract：BACKGROUND:The incidence of bronchioloalveolar carcinoma of the lung (BAC), a pathologically distinct type of nonsmall cell lung carcinoma (NSCLC), appears to be rising. In this study, the authors compared data on the clinical presentation and clinical courses of patients with Stage IIIB and IV BAC with data on other t...

journal_title：Cancer

authors： Breathnach OS,Ishibe N,Williams J,Linnoila RI,Caporaso N,Johnson BE

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Primary lymphomas of the uterus or cervix are so rare that treatment series of single institutions consist of very small numbers of patients, making standard treatment difficult to define. The outcome of patients treated with a combination of chemotherapy and radiation therapy was analyzed for all but patien...

journal_title：Cancer

authors： Stroh EL,Besa PC,Cox JD,Fuller LM,Cabanillas FF

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Previous Phase II trials evaluating paclitaxel as a single agent have produced objective response rates of 38-40%. However, in these studies patients had recurrent disease and had received previous treatment with chemotherapy, radiation, surgery, or some combination of the same. To the authors' knowledge, th...

journal_title：Cancer

authors： Grecula JC,Smith RE,Rhoades CA,Sharma P,Agrawal A,Zhang H,Allen J,Goldman FP,Young D,Schuller DE

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the potential economic implications resulting from using exemestane (EXE), a new steroidal, irreversible aromatase inactivator, compared with megestrol acetate (MA) in patients with advanced breast carcinoma. METHODS:The model used the clinical results from the m...

journal_title：Cancer

authors： Hillner BE,Radice D

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Lung cancer (LC) is the most common fatal malignancy, but there are no useful tumor markers for diagnosis or monitoring. Mucin 1 has an established role as a marker in other malignancies, but has undergone limited assessment in LC. METHODS:Serum from 86 patients with LC and 24 with benign pulmonary disease ...

journal_title：Cancer

authors： Willsher PC,Xing PX,Clarke CP,Ho DW,McKenzie IF

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:There is limited information on outcomes of prostate carcinoma treatments given to screened patient populations for whom cancer is usually detected at an earlier stage. METHODS:The authors conducted a cross-sectional evaluation of quality-of-life outcomes for men with prostate carcinoma detected in screenin...

journal_title：Cancer

authors： Smith DS,Carvalhal GF,Schneider K,Krygiel J,Yan Y,Catalona WJ

更新日期：2000-03-15 00:00:00

abstract：:A prospective randomized trial by CALGB examined the relative value of four chemotherapy regimens in 537 patients with stage III B and IV Hodgkin's disease. A new combination BOPP, derived by substitution of BCNU for nitrogen mustard in the MOPP regimen, was compared to MOPP and to two 3-drug regimens, derived by remo...

journal_title：Cancer

authors： Nissen NI,Pajak TF,Glidewell O,Pedersen-Bjergaard J,Stutzman L,Falkson G,Cuttner J,Blom J,Leone L,Sawitsky A,Coleman M,Haurani F,Spurr CL,Harley JB,Seligman B,Cornell C Jr,Henry P,Senn HJ,Brunner K,Martz G,Maurice

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Circulating prostate cells can be detected in the venous blood of patients with clinically localized prostate carcinoma by applying reverse transcriptase-polymerase chain reaction (RT-PCR) techniques using primers specific for the prostate specific antigen (PSA) gene. This study evaluates whether the detecti...

journal_title：Cancer

authors： Ennis RD,Katz AE,de Vries GM,Heitjan DF,O'Toole KM,Rubin M,Buttyan R,Benson MC,Schiff PB

更新日期：1997-06-15 00:00:00

abstract：BACKGROUND:In a cohort including 5112 prostate cancer (pCa) patients, the authors investigated associations among triglycerides (TG), total cholesterol (TC), and pCa while taking into account glucose. METHODS:A cohort (n = 200,660) based on 4 groups of men, according to age at cohort entry, with TG, TC, and glucose me...

journal_title：Cancer

authors： Van Hemelrijck M,Garmo H,Holmberg L,Walldius G,Jungner I,Hammar N,Lambe M

更新日期：2011-05-15 00:00:00

abstract：:The ganglioside composition of neuroblastoma samples from 53 patients was determined. Tumor sites included the adrenals (15), and the thoracic (20), abdominal (15), and pelvic (3) areas. Age of the patients at the time of surgery ranged from 1 day to over 10 years and the Stage of the tumors from A to D. Differences i...

journal_title：Cancer

authors： Schengrund CL,Repman MA,Shochat SJ

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

journal_title：Cancer

authors： Nzeako UC,Goodman ZD,Ishak KG

更新日期：1995-08-15 00:00:00

abstract：:The hematologic factors of 16 female patients with breast carcinoma who had received adjuvant chemotherapy with L-phenylalanine-based programs for two years were compared with those for 13 normal female volunteers of similar age. The findings include significant suppression of the mean hemoglobin level, of leukocyte c...

journal_title：Cancer

authors： Corder MP,Jochimsen PR

更新日期：1982-06-15 00:00:00

abstract：BACKGROUND:Colonoscopy is the most widely used colorectal cancer (CRC) screening test in the United States. Through the detection and removal of potentially precancerous polyps, it can prevent CRC. However, CRC screening remains low among adults who are recommended for screening. The New Hampshire Colorectal Cancer Scr...

journal_title：Cancer

authors： Rice K,Sharma K,Li C,Butterly L,Gersten J,DeGroff A

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...

journal_title：Cancer

authors： Blumenthal DT,Rankin C,Eyre HJ,Livingston RB,Spence AM,Stelzer KJ,Rushing EJ,Berger MS,Rivkin SE,Cohn AL,Petersdorf SH

更新日期：2008-08-01 00:00:00

abstract：:Biologicals and biological response modifiers (BRMs) represent a new class of agents for cancer therapy. Historically, there have been many attempts to stimulate the immune response with nonspecific immunomodulators in the form of bacterial extracts, viruses, and chemicals. Although these approaches have occasionally ...

journal_title：Cancer

authors： Oldham RK,Thurman GB,Talmadge JE,Stevenson HC,Foon KA

更新日期：1984-12-01 00:00:00

abstract：:Major advances have been made in melanoma treatment with the use of molecularly targeted therapies and immunotherapies, and numerous regimens are now approved by the US Food and Drug Administration for patients with stage IV disease. However, therapeutic resistance remains an issue to both classes of agents, and relia...

journal_title：Cancer

authors： Szczepaniak Sloane RA,Gopalakrishnan V,Reddy SM,Zhang X,Reuben A,Wargo JA

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Nonionizing radiation, such as radiofrequency field and near infrared laser, induces thermal cytotoxicity in cancer cells treated with gold nanoparticles. Quantum dots are fluorescent semiconducting nanoparticles that were hypothesized to induce similar injury after radiofrequency field irradiation. METHODS...

journal_title：Cancer

authors： Glazer ES,Curley SA

更新日期：2010-07-01 00:00:00

abstract：:Peripheral blood lymphocytes of patients with multiple myeloma, macroglobulinemia, and monoclonal gammopathy of uncertain significance were analyzed for B cells, and cells bearing kappa light chains and lambda light chains on their surfaces. Compared with controls, the number of B cells were decreased in all three gro...

journal_title：Cancer

authors： Dillman RO,Royston I,Meserve BL,Griffiths JC

更新日期：1981-11-15 00:00:00

abstract：BACKGROUND:The authors previously demonstrated that never-smokers with stage IIIB/IV nonsmall cell lung cancer (NSCLC) lived 50% longer than former/current smokers. This observation persisted after adjusting for age, performance status, and sex. In this study, the authors hypothesized that smoking-dependent differences...

journal_title：Cancer

authors： Paik PK,Johnson ML,D'Angelo SP,Sima CS,Ang D,Dogan S,Miller VA,Ladanyi M,Kris MG,Riely GJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Multifocal tumor areas occurred in 12-22% of patients with renal cell carcinoma. It is unknown whether these tumors have malignant potential and characterize a higher risk for metastases. The performance of nephron-sparing surgery in patients with low grade or low stage tumors is controversial. METHODS:Prim...

journal_title：Cancer

authors： Junker K,Schlichter A,Junker U,Knöfel B,Kosmehl H,Schubert J,Claussen U

更新日期：1997-03-01 00:00:00

abstract：:This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (> 3 fmol/mg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to hypophysectomy. E...

journal_title：Cancer

authors： Manni A,Arafah B,Pearson OH

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:Genomic testing is increasingly performed in oncology, but concerns remain regarding the clinician's ability to interpret results. In the current study, the authors sought to determine the agreement between physicians and genomic annotators from the Precision Oncology Decision Support (PODS) team at The Univ...

journal_title：Cancer

authors： Brusco LL,Wathoo C,Mills Shaw KR,Holla VR,Bailey AM,Johnson AM,Khotskaya YB,Litzenburger BC,Sanchez NS,Zeng J,Bernstam EV,Eng C,Kee BK,Amaria RN,Routbort MJ,Mills GB,Mendelsohn J,Meric-Bernstam F

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Screening colonoscopy (SC) for colorectal cancer (CRC) is underused by Latino individuals. The current randomized clinical trial examined the impact of 3 interventions: 1) patient navigation; 2) patient navigation plus standard Centers for Disease Control and Prevention print materials; and 3) patient naviga...

journal_title：Cancer

authors： DuHamel KN,Schofield EA,Villagra C,Sriphanlop P,Itzkowitz SH,Cotter G,Cohen N,Erwin DO,Winkel G,Thompson HS,Zauber AG,Jandorf LH

更新日期：2020-02-15 00:00:00

abstract：:The authors present the case of a 40-year-old white man with an obstructing laryngeal mass. Despite considerable tumor size, results of repeated biopsies revealed widespread carcinoma in situ with chronic inflammation within the subcutaneous tissues, and only after extensive endoscopic "debulking" of the mass was a sm...

journal_title：Cancer

authors： Eskinazi DP,Mihail R,Dichtel WG

更新日期：1985-08-01 00:00:00

abstract：:A leukocyte migration procedure was utilized to test cellular hypersensitivity of breast cancer patients' leukocytes to autologous and homologous breast cancer tissues and to murine milk containing murine mammary tumor virus (MuMTV). The in vitro responsiveness of the leukocytes and the antigenicity of breast cancer t...

journal_title：Cancer

authors： Black MM,Zachrau RE,Shore B,Moore DH,Leis HP Jr

更新日期：1975-01-01 00:00:00

abstract：:In a former series of 60 resected Stage II nonseminomatous germinal testis tumors the authors succeeded in demonstrating that adjuvant cisplatin, vinblastine, and bleomycin (PVB) was able to significantly improve survival (100% in 11 treated versus 28.5% in 7 historical controls, P less than 0.01) only in patients wit...

journal_title：Cancer

authors： Pizzocaro G,Zanoni F,Milani A,Piva L,Salvioni R,Pasi M,Pilotti S,Monfardini S

更新日期：1984-03-15 00:00:00