Insulin signalling in human adipose tissue.

abstract：OBJECTIVE:The potentially beneficial effects of pomegranate peel (PPE), flower (PFE) and seed oil (PSO) extracts, in comparison with rosiglitazone, on adiposity, lipid profile, glucose homoeostasis, as well as on the underlying inflammatory mechanisms, were examined in high-fat and high-sucrose (HF/HS) diet-induced obe...

journal_title：Archives of physiology and biochemistry

authors： Harzallah A,Hammami M,Kępczyńska MA,Hislop DC,Arch JR,Cawthorne MA,Zaibi MS

更新日期：2016-01-01 00:00:00

abstract：:Due to the importance of zinc as an antioxidant and its crucial role in insulin synthesis, its deficiency may affect adversely diabetic state. So, this study aimed to modulate these effects using Curcuma longa as natural antioxidant. Rats were divided into four groups: two groups fed a zinc sufficient diet one non-dia...

journal_title：Archives of physiology and biochemistry

authors： Tebboub I,Kechrid Z

更新日期：2019-06-19 00:00:00

abstract：AIM:A high-fat diet (HFD) can lead to obesity and related metabolic disorders. This study evaluated the preventive efficacy of myricetin derivative-rich fraction (MD) from Syzygium malaccense leaf extract against HFD-induced obesity, hyperglycaemia, and oxidative stress in C57BL/6J mice. METHODS:HFD-fed mice were admi...

journal_title：Archives of physiology and biochemistry

authors： Nallappan D,Ong KC,Palanisamy UD,Chua KH,Kuppusamy UR

更新日期：2020-08-19 00:00:00

abstract：:This research was designed to detect the function of low-density lipoprotein receptor (LDLR)-related protein 8 (LRP8) in breast cancer (BC). Our results revealed that LRP8 was highly expressed in BC tissues and cell lines compared with human normal breast tissues. The poor prognosis of patients with BC was associated ...

journal_title：Archives of physiology and biochemistry

authors： Li L,Qu WH,Ma HP,Wang LL,Zhang YB,Ma Y

更新日期：2020-01-29 00:00:00

abstract：:Septic encephalopathy (SE) is a devastating consequence of sepsis, a hyper-triggered host response against infectious challenge, which ultimately leads to brain damage. The present study examined whether sevoflurane (SVF), a volatile anaesthetic, can counteract the perturbation of homeostasis in a caecal ligation and ...

journal_title：Archives of physiology and biochemistry

authors： Chen H,Peng Y,Wang L,Wang X

更新日期：2020-06-13 00:00:00

abstract：:Evidence is presented of a Mg2+ and Ca(2+)-activated ATPase at the surface of cultured rat glomerular mesangial cells. Substrate specificity was very low when different nucleoside-5'-triphosphates were examined. The apparent Km values were 0.46 and 0.32 mM for Mg(2+)-ATPase and Ca(2+)-ATPase, respectively. Inhibition ...

journal_title：Archives of physiology and biochemistry

authors： Stefanović V,Vlahović P

更新日期：1995-04-01 00:00:00

abstract：CONTEXT:Essential oils from Pinus species have been reported to have various therapeutic properties. OBJECTIVE:This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro. MATERIAL AND METHODS:Th...

journal_title：Archives of physiology and biochemistry

authors： Bouzenna H,Hfaiedh N,Bouaziz M,Giroux-Metges MA,Elfeki A,Talarmin H

更新日期：2017-12-01 00:00:00

abstract：:The early and late effects of alloxan-diabetes and insulin treatment on kinetic properties of mitochondrial FoF1 ATPase were examined. Diabetic state resulted in significant decrease in the activity while insulin treatment caused hyper-stimulation. In control animals the enzyme activity resolved in three kinetic compo...

journal_title：Archives of physiology and biochemistry

authors： Patel SP,Katyare SS

更新日期：2006-07-01 00:00:00

abstract：:This study investigated the expression and underlying molecular mechanism of CPSF1 in diabetic retinopathy. Streptozotocin (STZ)-induced Sprague-Dawley (SD) rats were employed as a diabetic model, and high-glucose (HG)-induced human retinal vascular endothelial cells （HRVECs）were used as an in vitro experimental model...

journal_title：Archives of physiology and biochemistry

authors： Zhang J,Zhang X,Zou Y,Han F

更新日期：2020-02-12 00:00:00

abstract：CONTEXT:Metabolic syndrome (MetS) is a clustering of several physiological alterations. OBJECTIVE:This study was designed to evaluate the effects of MetS on rats spermatogenesis and steroidogenesis. MATERIALS AND METHODS:We developed a MetS rodent model using high-sugar and high-fat diet. RESULTS:MetS rats showed se...

journal_title：Archives of physiology and biochemistry

authors： Rahali D,Dallagi Y,Hupkens E,Veegh G,Mc Entee K,Asmi ME,El Fazaa S,El Golli N

更新日期：2020-09-04 00:00:00

abstract：:The roles of leptin, nesfatin-1 and kisspeptin in the regulation of food intake and/or reproduction are well known; however, the interactions between these hormones remain unclear, especially in humans. The aim of this study was to determine the roles of leptin, nesfatin-1 and kisspeptin in pre- and postmenopausal obe...

journal_title：Archives of physiology and biochemistry

authors： Çelik F,Belviranli M,Okudan N

更新日期：2016-10-01 00:00:00

abstract：:The powerful vasoconstrictor peptide endothelin-1 (ET1) has been shown to reduce local cerebral blood flow in brain areas supplied by the middle cerebral artery (MCA) to a pathologically low level upon intracerebral injection adjacent to the MCA. This reduction manifests itself as an ischemic infarct, that is fully de...

journal_title：Archives of physiology and biochemistry

authors： Moyanova S,Kortenska L,Kirov R,Iliev I

更新日期：1998-12-01 00:00:00

abstract：:A total of 45 preruminant goats were fed either goat milk or a milk substitute. The postnatal development of bile secretion and biliary lipids composition of suckling goats and the influence upon these parameters of maternal milk substitution were studied during the first month of life. Samples of hepatic and gallblad...

journal_title：Archives of physiology and biochemistry

authors： Rueda A,Valverde A,Fernandez JA,Martinez-Victoria E,Naranjo JA,Mañas M

更新日期：1996-01-01 00:00:00

abstract：:Investigations were undertaken to obtain information on the mechanism by which orally administered spermine induces postnatal maturation in the rat intestine. Suckling rats ingested one dose of spermine (8 mumol) then were sacrificed at different intervals. -A. Proximal and distal parts of the intestine were homogenis...

journal_title：Archives of physiology and biochemistry

authors： Wéry I,Deloyer P,Dandrifosse G

更新日期：1996-01-01 00:00:00

abstract：:Context: Recent surveys have shown an association between proprotein convertase subtilisin/kexin type 9 (PCSK9) and oxidative stress.Objective: In this investigation, the effect of evolocumab an anti-PCSK9 antibody was assessed against oxidative damage caused by hydrogen peroxide (H2O2) in human umbilical vein endothe...

journal_title：Archives of physiology and biochemistry

authors： Safaeian L,Mirian M,Bahrizadeh S

更新日期：2020-07-03 00:00:00

abstract：:This study was to investigate whether epidermal growth factor (EGF) may induce any long-term effect on pancreatic exocrine function in vivo as well to evaluate the chronic effects of EGF on pancreatic growth in rats. Rats were treated with EGF (10 micrograms/kg) for 5 or 7 days. EGF infused intravenously (2 micrograms...

journal_title：Archives of physiology and biochemistry

authors： Lajas AI,Pozo MJ,Salido GM,Singh J,Pariente JA

更新日期：1996-01-01 00:00:00

abstract：:The effect of underfeeding over glucose metabolism in uteri isolated from ovariectomized and non-ovariectomized rats subjected to a restricted diet for 25 days (50% of the normal food intake), was studied. Underfeeding decreases (14)CO(2) formation from U(14) C-glucose in intact animal uteri. While in ovariectomized r...

journal_title：Archives of physiology and biochemistry

authors： Campos ML,Casalino-Matsuda SM,Linares JA,Goldraij A

更新日期：2000-12-01 00:00:00

abstract：:Folliculo-stellate cells (FS-cells) in the anterior pituitary gland are star-shaped cells and form tiny follicles. FS-cells are positive for S-100 protein and produce many cytokines or growth factors, such as interleukin-6 (IL-6), leukemia inhibitory factor (LIF), basic fibroblastic growth factor (bFGF) and vascular e...

journal_title：Archives of physiology and biochemistry

authors： Inoue K,Mogi C,Ogawa S,Tomida M,Miyai S

更新日期：2002-04-01 00:00:00

abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...

journal_title：Archives of physiology and biochemistry

authors： Bassey IE,Ikpi DE,Isong IKP,Akpan UO,Onyeukwu CC,Nwankwo NP,Udofia IG

更新日期：2020-01-25 00:00:00

abstract：:Changes in body fluid distribution are known to influence neuroendocrine function. The aim of the present study was to test the hypothesis that changes in plasma volume affect the counterregulatory neuroendocrine response to hypoglycemia. The tests were performed in 12 subjects in two situations: 'head-up' (+60 degree...

journal_title：Archives of physiology and biochemistry

authors： Radikova Z,Penesova A,Jezova D,Kvetnansky R,Vigas M,Macho L,Koska J

更新日期：2003-10-01 00:00:00

abstract：:Stimulation of cellular fatty acid uptake by induction of insulin signalling or AMP-kinase (AMPK) activation is due to translocation of the fatty acid-transporter CD36 from intracellular stores to the plasma membrane (PM). For investigating the role of the four Cys-residues within CD36's cytoplasmic tails in CD36 tran...

journal_title：Archives of physiology and biochemistry

authors： van Oort MM,Drost R,Janβen L,Van Doorn JM,Kerver J,Van der Horst DJ,Luiken JJ,Rodenburg KC

更新日期：2014-02-01 00:00:00

abstract：:When neurotransmitters bind to their specific receptors in the membrane of nerve and muscle cells they induce conformational transitions leading to the formation of open receptor-channels and desensitized receptor forms. A knowledge of the rate and equilibrium constants associated with these transitions is required to...

journal_title：Archives of physiology and biochemistry

authors： Hess GP

更新日期：1996-10-01 00:00:00

abstract：CONTEXT:Glucose-6-phosphate dehydrogenase (G6PD) is an important enzyme of hexose monophosphate shunt, involved in the biosynthesis of reduced nicotinamide adenine dinucleotide phosphate hydrogen (NADPH). OBJECTIVE:This study was designed to investigate age-dependent changes in human erythrocyte G6PD activity. The G6P...

journal_title：Archives of physiology and biochemistry

authors： Maurya PK,Kumar P,Chandra P

更新日期：2016-01-01 00:00:00

abstract：:Objective: We aimed to determine myo-inositol oxygenase (MIOX) activity in gestational diabetes mellitus (GDM).Material and Methods: The insulin, HbA1c, and MIOX levels of 80 pregnant women were analysed after 75 g OGTT. Group I included patients with no risk factor for GDM, Group II: patients with high risk for GDM, ...

journal_title：Archives of physiology and biochemistry

authors： Kısa B,Sert UY,Celik HK,Candar T,Erol Koç EM,Taşcı Y,Çağlar GS

更新日期：2020-03-19 00:00:00

abstract：:Background: We investigated whether the anti-inflammatory and antioxidant agent, resveratrol can inhibit type 2 diabetes mellitus (T2DM)-induced osteoarthritis (OA) in rats and whether it is associated with the suppression of glycaemia, dyslipidemia and inflammatory and oxidative stress biomarkers.Materials and method...

journal_title：Archives of physiology and biochemistry

authors： Ebrahim HA,Alzamil NM,Al-Ani B,Haidara MA,Kamar SS,Dawood AF

更新日期：2020-06-04 00:00:00

abstract：:The dysregulation of microRNA expression is significantly associated with the initiation and development of CRC. miR-124 is markedly downregulated in colorectal cancer. In the present study, the effects of methylation, over expression and downregulation of miR-124 and its target gene DNMT3B on the proliferation, migra...

journal_title：Archives of physiology and biochemistry

authors： Shahmohamadnejad S,Nouri Ghonbalani Z,Tahbazlahafi B,Panahi G,Meshkani R,Emami Razavi A,Shokri Afra H,Khalili E

更新日期：2020-06-18 00:00:00

abstract：OBJECTIVE:To determine the relationship of biochemical parameters, BMI and blood pressure with age, gender and ethnicity of Trinidadian type 2-diabetic subjects. METHODS:A retrospective case control study comprised of 1794 patient (740 males and 1054 females). RESULTS:The correlation was found for lipid profile with ...

journal_title：Archives of physiology and biochemistry

authors： Nayak BS,Maharaj N,Fatt LA,Legall G

更新日期：2012-02-01 00:00:00

abstract：:We investigated the effects of tauroursodeoxycholic acid (TUDCA) to assess whether this acid may also have "protective" effects similar to those found with ursodeoxycholic acid (UDCA). We used a well-known amphibian model of gastric mucosa, and studied the effects of taurodeoxycholic acid (TDCA) on electrical transepi...

journal_title：Archives of physiology and biochemistry

authors： Piepoli AL,Caroppo R,Armentano R,Caruso ML,Guerra V,Maselli MA

更新日期：2002-07-01 00:00:00

abstract：:Glycogen synthesis increases after muscle contraction and during insulin stimulation, and insulin-stimulated glycogen synthesis is enhanced after contraction. We hypothesized that the initial glycogen content influences the magnitude of additive effect of contraction on insulin-stimulated glycogen synthesis. Contracti...

journal_title：Archives of physiology and biochemistry

authors： Lai YC,Stuenaes JT,Kuo CH,Jensen J

更新日期：2010-07-01 00:00:00

abstract：:In the suckling rats, orally provided spermine induced structural and biochemical changes in the intestine, which are characteristics of the postnatal maturation. This induced maturation was compared to that occurring spontaneously. Eight mumol spermine were administered orally once a day, for one or three days, to su...

journal_title：Archives of physiology and biochemistry

authors： Peulen O,Pirlet C,Klimek M,Goffinet G,Dandrifosse G

更新日期：1998-02-01 00:00:00