Abstract:
:The 2,3-dihydroxy-6-bromo-pyrazino-[2,3-beta]-pyrazine is a substance selected during the antiviral screening of pyrazino-pyrazine derivatives. The compound shows antiviral activity in vitro against measles, NDV, some influenza viruses and against herpes simplex and zoster, infectious canine hepatitis and vaccinia viruses. It had no effect on ECHO 9 virus. Therapeutic trials showed activity also on herpetic keratoconjunctivitis experimentally induced in rabbits.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Verini MA,Fioretti A,Casazza AM,Sanfilippo A,Palamidessi G,Ghione Mdoi
10.1159/000221862subject
Has Abstractpub_date
1975-01-01 00:00:00pages
221-30issue
3-4eissn
0009-3157issn
1421-9794journal_volume
21pub_type
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