Abstract:
:Olfactory information is first encoded in a combinatorial fashion by olfactory bulb glomeruli, which individually represent distinct chemical features of odors. This information is then transmitted to piriform (olfactory) cortex, via axons of olfactory bulb mitral and tufted (M/T) cells, where it is presumed to form the odor percept. However, mechanisms governing the integration of sensory information in mammalian olfactory cortex are unclear. Here we show that single M/T cells can make powerful connections with cortical pyramidal cells, and coincident input from few M/T cells is sufficient to elicit spike output. These findings suggest that odor coding is broad and distributed in olfactory cortex.
journal_name
Neuronjournal_title
Neuronauthors
Franks KM,Isaacson JSdoi
10.1016/j.neuron.2005.12.026subject
Has Abstractpub_date
2006-02-02 00:00:00pages
357-63issue
3eissn
0896-6273issn
1097-4199pii
S0896-6273(06)00009-2journal_volume
49pub_type
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