Macrophage-derived cytokine and nitric oxide profiles in type I and type II diabetes mellitus: effect of thymoquinone.

abstract：:The renin-angiotensin system (RAS) has an important role in the endocrine pancreas. Multiple researches have shown that even in the insulin resistance phase, there are many abnormalities in islets morphology and function. This study aimed at investigating the effects of RAS blockade on the islets function in rats with...

journal_title：Acta diabetologica

authors： Yuan L,Li X,Li J,Li HL,Cheng SS

更新日期：2013-08-01 00:00:00

abstract：:Kidney volume was measured during pregnancy in insulin-dependent diabetic women by an ultrasound technique and prognostic value of these measurements evaluated. A prospective study was performed on 87 pregnant women with insulin-dependent diabetes attending the maternity clinic of Aarhus Kommunehospital. Patients with...

journal_title：Acta diabetologica

authors： Lauszus FF,Klebe JG,Rasmussen OW,Klebe TM,Dørup J,Christensen T

更新日期：1995-12-01 00:00:00

abstract：:The aim of this study was to compare the efficacy of treatment with insulin alone, insulin plus acarbose, insulin plus metformin, or insulin plus rosiglitazone in type 2 diabetic subjects who were previously on insulin monotherapy, and to evaluate the effects of these treatments on cardiovascular risk factors includin...

journal_title：Acta diabetologica

authors： Yilmaz H,Gursoy A,Sahin M,Guvener Demirag N

更新日期：2007-12-01 00:00:00

abstract：AIMS:Fetuin-A has been linked to insulin resistance and obesity. Its role in the pathogenesis of type 2 diabetes (T2DM) has also been discussed. We aimed to investigate the prospective association of fetuin-A and the risk of T2DM in a systematic review and meta-analysis. METHODS:A systematic search of studies from the...

journal_title：Acta diabetologica

authors： Guo VY,Cao B,Cai C,Cheng KK,Cheung BMY

更新日期：2018-01-01 00:00:00

abstract：:A cross-sectional descriptive study was done on patients recently entered into the National Diabetes Registry in Eritrea where the prevalence was estimated to be 2.2% based on patient information in 2004. Of the 627 patients with diabetes, two thirds were type 2. Although type 1 had poorer control (42.9%) than type 2 ...

journal_title：Acta diabetologica

authors： Seyum B,Mebrahtu G,Usman A,Mufunda J,Tewolde B,Haile S,Kosia A,Negassi E

更新日期：2010-03-01 00:00:00

abstract：AIMS:Hypoglycaemia represents a critical burden with clinical and social consequences in the management of diabetes. Serum uric acid (SUA) has been associated with cardiovascular diseases (CVD), but no conclusive findings are available nowadays in patients suffering from hypoglycaemia. We investigated whether SUA level...

journal_title：Acta diabetologica

authors： Bonaventura A,Gallo F,Carbone F,Liberale L,Maggi D,Sacchi G,Dallegri F,Montecucco F,Cordera R

更新日期：2018-04-01 00:00:00

abstract：:Post-prandial hyperglycemia is considered a relevant therapeutic target in type 2 diabetic patients, and it could represent per se an independent risk factor for diabetic complications. Aim of the present systematic review is to collect and summarize evidence from observational studies on the relationship between post...

journal_title：Acta diabetologica

authors： Mannucci E,Monami M,Lamanna C,Adalsteinsson JE

更新日期：2012-08-01 00:00:00

abstract：:We investigated whether food supplementation within the first year life or age at introduction of gluten-containing foods influenced the risk of developing islet autoimmunity and type 1 diabetes. A total of 2,291 children with a family history of type 1 diabetes were prospectively followed from birth for 28,983 patien...

journal_title：Acta diabetologica

authors： Chmiel R,Beyerlein A,Knopff A,Hummel S,Ziegler AG,Winkler C

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:International comparisons of diabetes-related lower extremity amputation rates are still hampered by different criteria used for data collection and analysis. We aimed to evaluate trends and variation of major/minor amputations, using agreed definitions adopted by the Organization for Economic Cooperation an...

journal_title：Acta diabetologica

authors： Carinci F,Uccioli L,Massi Benedetti M,Klazinga NS

更新日期：2020-03-01 00:00:00

abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

journal_title：Acta diabetologica

authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

更新日期：2020-04-01 00:00:00

abstract：:To evaluate the role of insulin resistance and beta cell function to increasing fasting plasma glucose (FPG), 1,272 Chinese subjects (18-80 years of age) were divided into normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), combined glucose intolerance (CGI), and type 2 di...

journal_title：Acta diabetologica

authors： Bi Y,Zhu D,Jing Y,Hu Y,Feng W,Shen S,Tong G,Shen X,Yu T,Song D,Yang D

更新日期：2012-12-01 00:00:00

abstract：:We have measured protein phosphatase (PP) activity in crude homogenates as well as in the total 105.000 x g supernatant and precipitate fractions from normal rat pancreatic islets. On the basis of the inhibition produced by either 1 nM or 1 microM okadaic acid, both PP1 and PP2A activity were present in crude islet ho...

journal_title：Acta diabetologica

authors： Gagliardino JJ,Rossi PF,García ME

更新日期：1997-03-01 00:00:00

abstract：:The duration of diabetes before puberty is not considered relevant to the future development of complications. To evaluate the effects of diabetes on the neural retina, we analysed macular function by steady-state focal electroretinography in 20 prepubescent diabetic children without vascular retinopathy and in 39 sex...

journal_title：Acta diabetologica

authors： Greco AV,Di Leo MA,Caputo S,Falsini B,Porciatti V,Marietti G,Ghirlanda G

更新日期：1994-06-01 00:00:00

abstract：:The aim of this study was to evaluate the prevalence of thyroid autoantibodies and clinical significance of thyroid autoimmunity in children with the diagnosis of diabetes mellitus type 1. The study group comprised 222 children all with newly diagnosed diabetes mellitus type 1 (122 boys) with a mean age 9.92 +/- 4.5 y...

journal_title：Acta diabetologica

authors： Machnica L,Osior A,Jarosz-Chobot P,Deja G,Polanska J,Otto-Buczkowska E

更新日期：2008-03-01 00:00:00

abstract：AIMS:The aim of the study was to evaluate and compare continuous subcutaneous insulin infusion (CSII) use in pediatric and adult age groups. METHODS:Data were collected with a questionnaire sent by e-mail to CSII-experienced Diabetes Centers. The questionnaire assessed: (1) number of CSII-treated patients; (2) patient...

journal_title：Acta diabetologica

authors： Bonfanti R,Lepore G,Bozzetto L,Corsi A,Di Blasi V,Girelli A,Grassi G,Iafusco D,Rabbone I,Schiaffini R,Laviola L,Bruttomesso D,Italian Study Group on Diffusion of CSII in Italy.

更新日期：2016-06-01 00:00:00

abstract：AIMS:The anti-inflammatory effects of the polyphenol resveratrol in patients with type 2 diabetes mellitus (T2DM) are controversial. Its role on pentraxin 3 (PTX3) concentrations, a human acute phase protein, has never been evaluated. Our aim was to determine whether a two-dosage resveratrol supplementation (500 and 40...

journal_title：Acta diabetologica

authors： Bo S,Ponzo V,Evangelista A,Ciccone G,Goitre I,Saba F,Procopio M,Cassader M,Gambino R

更新日期：2017-05-01 00:00:00

abstract：:We analysed the risk factors associated with diabetic complications in the cohort of patients assisted by a type 2 diabetes mellitus (T2DM) shared-care program. We analysed registry data from 16,136 T2DM patients. Of them, 4,781 had microangiopathy, 3,469 CV events. They were 70.5 ± 17.1 years old, 50% were male, dise...

journal_title：Acta diabetologica

authors： Ciardullo AV,Daghio MM,Bevini M,Feltri G,Novi D,Fattori G,Borsari S,Donato CD

更新日期：2010-12-01 00:00:00

abstract：:Fasting glucose and oral glucose tolerance test (OGTT) criteria for glucose homeostasis were compared in a cross-sectional cluster, community study in Accra, Ghana. A total of 4636 subjects without prior diagnosis of diabetes had fasting plasma glucose, 2-hour OGTT and measurement of cardiovascular risk factors. Mean ...

journal_title：Acta diabetologica

authors： Amoah AG

更新日期：2002-04-01 00:00:00

abstract：AIMS:Prognostic significance of apolipoproteins in diabetic retinopathy risk has not been well investigated. The aim of this study was to reveal the relationship between the risk of diabetic retinopathy and the levels of several apolipoproteins and their ratios in a 10-year prospective cohort. METHODS:A total of 1023 ...

journal_title：Acta diabetologica

authors： Zhang Q,Hu J,Hu Y,Ding Y,Zhu J,Zhuang C

更新日期：2018-07-01 00:00:00

abstract：:Pancreatic volume and fat content might be associated with β-cell function or insulin resistance (IR). We investigated the difference in pancreatic volume and fat content between age- and body mass index (BMI)-matched normal subjects and patients with having different durations of type 2 diabetes (T2D). We compared pa...

journal_title：Acta diabetologica

authors： Lim S,Bae JH,Chun EJ,Kim H,Kim SY,Kim KM,Choi SH,Park KS,Florez JC,Jang HC

更新日期：2014-10-01 00:00:00

abstract：AIMS:The purpose of this study was to investigate the mechanism of vascular endothelial cell apoptosis induced by acute blood glucose fluctuation. METHODS:Thirty rats were assigned to three groups: normal saline (SAL group), constant high glucose (CHG group) and acute blood glucose fluctuation (AFG) group. Other forty...

journal_title：Acta diabetologica

authors： Wu N,Shen H,Wang Y,He B,Zhang Y,Bai Y,Du R,Du Q,Han P

更新日期：2017-08-01 00:00:00

abstract：:The recent efforts in the study of fetal compartments could help us to a better recognition of the proper fetal growth and well being. Fat content correlates directly with energy stores. Fat mass and lean body mass is often used in the nutritional assessment of the individual. Moreover chromosomal abnormalities may be...

journal_title：Acta diabetologica

authors： Valensise H,Larciprete G,Arduini D,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：AIMS:The aims of this study were: to develop new equations for predicting resting energy expenditure (REE) in obese Italian subjects according to body composition parameters; to compare them with predicted values estimated by other REE prediction equations; and to cross-validate our equations using a validation set coh...

journal_title：Acta diabetologica

authors： De Lorenzo A,Di Renzo L,Morini P,de Miranda RC,Romano L,Colica C

更新日期：2018-01-01 00:00:00

abstract：:The objective of the study was to determine the prevalence of known diabetes among elderly subjects receiving nursing care in a north Norwegian population, to screen for new cases using HbA1c measurement and to evaluate the quality of care for those with diabetes. Men and women, with and without known diabetes, above ...

journal_title：Acta diabetologica

authors： Jorde R,Hagen T

更新日期：2006-08-01 00:00:00

abstract：AIMS:Glucose-dependent insulinotropic polypeptide (GIP) is released primarily from the proximal small intestine and glucagon-like peptide-1 (GLP-1) from the more distal small intestine and colon. Their relative importance to the incretin effect in health has been contentious in the past, although it now appears that GI...

journal_title：Acta diabetologica

authors： Marathe CS,Pham H,Marathe JA,Trahair LG,Huynh L,Wu T,Phillips LK,Rayner CK,Nauck MA,Horowitz M,Jones KL

更新日期：2020-05-01 00:00:00

abstract：:Left atrial (LA) structural, functional and mechanical changes have important role in development of diabetic cardiomyopathy and it was discovered that LA remodeling has important prognostic role in the patients with diabetes (DM). Previously the focus of echocardiographic studies in DM population was on the left vent...

journal_title：Acta diabetologica

authors： Tadic M,Cuspidi C

更新日期：2020-06-09 00:00:00

abstract：:Endothelial nitric oxide synthase (eNOS) has been shown to play an essential role in retinal vascular function, and disequilibrium in its production can lead to diabetic retinopathy (DR). Genetic polymorphisms of eNOS gene have been suggested to play a role in nitric oxide (NO) abnormalities which may contribute to th...

journal_title：Acta diabetologica

authors： Cheema BS,kohli HS,Sharma R,Bhansali A,Khullar M

更新日期：2012-12-01 00:00:00

abstract：:Continuous subcutaneous insulin infusion (CSII) is effective and safe in children and adults with type 1 diabetes. Notwithstanding, some patients decide to discontinue using CSII. We evaluated the discontinuation rate, and its related factors, in a large group of children and adolescents with type 1 diabetes using CSI...

journal_title：Acta diabetologica

authors： Lombardo F,Scaramuzza AE,Iafusco D

更新日期：2012-12-01 00:00:00

abstract：:Correct classification of diabetic patients in adulthood at the time of diagnosis is often difficult. Some may be initially diagnosed as having non-insulin-dependent diabetes mellitus and be treated with diet and/or oral hypoglycaemic agents (OHA) but later require insulin treatment. Islet cell antibodies and antibodi...

journal_title：Acta diabetologica

authors： Hatziagelaki E,Jaeger C,Maeser E,Bretzel RG,Federlin K

更新日期：1996-12-01 00:00:00

abstract：:The objective of this study was to verify the impact of various sports on body cell mass (BCM). Ninety-eight male subjects, 17-33 years of age, participated in the study. The sample included athletes from three professional Italian football (soccer) teams, representing three different divisions (A, n=16; B, n=14; and ...

journal_title：Acta diabetologica

authors： Andreoli A,Melchiorri G,Brozzi M,Di Marco A,Volpe SL,Garofano P,Di Daniele N,De Lorenzo A

更新日期：2003-10-01 00:00:00