Levels of serum uric acid at admission for hypoglycaemia predict 1-year mortality.

abstract：AIMS:To assess the metabolic health of obese and non-obese women at high GDM risk 5 years postpartum. METHODS:This is a secondary analysis of the 5-year follow-up of the RADIEL GDM prevention study including 333 women at high GDM risk (BMI ≥ 30 kg/m2 and/or previous GDM). Five years postpartum metabolic health was ass...

journal_title：Acta diabetologica

authors： Huvinen E,Eriksson JG,Koivusalo SB,Grotenfelt N,Tiitinen A,Stach-Lempinen B,Rönö K

更新日期：2018-05-01 00:00:00

abstract：AIMS:Radiolabeled Exendin-4 has been proposed as suitable imaging marker for pancreatic beta cell mass quantification mediated by Glucagon-like peptide-1 receptor (GLP-1R). However, noticeable species variations in basal pancreatic uptake as well as uptake reduction degree due to selective beta cell ablation were obser...

journal_title：Acta diabetologica

authors： Eriksson O,Rosenström U,Selvaraju RK,Eriksson B,Velikyan I

更新日期：2017-11-01 00:00:00

abstract：:The effect of a phenacyl imidazolium compound (LY177507 or Proglycosyn, Eli Lilly) on the direct (glucose-->glucose-6-phosphate-->glycogen) and indirect (three-carbon compounds-->glucose-6-phosphate-->glycogen) pathways of liver glycogen synthesis was studied in conscious rats. [1-13C]Glucose (99% enriched) was infuse...

journal_title：Acta diabetologica

authors： Cline GW,Greenawalt K,Shulman GI

更新日期：1993-01-01 00:00:00

abstract：:Several haemostatic abnormalities are associated with proliferative diabetic retinopathy. While abnormalities in plasma fibrinolytic activity have been described in diabetic retinopathy, platelets (a rich source of plasminogen activator inhibitor type 1, PAI-1) have received little attention. As a result, little is kn...

journal_title：Acta diabetologica

authors： Simpson AJ,Booth NA,Moore NR,Lewis SJ,Gray RS

更新日期：1999-09-01 00:00:00

abstract：:Bovine insulin was glycated by in vitro incubation with 20-220 mM D-glucose for 1-48 h. The percentage of glycation was dependent on time, glucose concentration, temperature and pH, attaining values up to 28%. Glucose-lowering activities of glycated and control (non-glycated) insulin preparations were assessed in mice...

journal_title：Acta diabetologica

authors： Abdel-Wahab YH,O'Harte FP,Boyd AC,Barnett CR,Flatt PR

更新日期：1997-12-01 00:00:00

abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...

journal_title：Acta diabetologica

authors： Pozzuoli GM,Laudato M,Barone M,Crisci F,Pozzuoli B

更新日期：2018-01-01 00:00:00

abstract：:Serum total bilirubin (TB) is a potent antioxidant and inversely associated with metabolic syndrome (MetS) in Asian populations. However, there has been no study which is aimed to investigate whether TB is a risk factor for MetS or not. We investigated cross-sectional and longitudinal associations between TB and MetS ...

journal_title：Acta diabetologica

authors： Oda E,Aizawa Y

更新日期：2013-06-01 00:00:00

abstract：:The recent efforts in the study of fetal compartments could help us to a better recognition of the proper fetal growth and well being. Fat content correlates directly with energy stores. Fat mass and lean body mass is often used in the nutritional assessment of the individual. Moreover chromosomal abnormalities may be...

journal_title：Acta diabetologica

authors： Valensise H,Larciprete G,Arduini D,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：:Endothelial nitric oxide synthase (eNOS) has been shown to play an essential role in retinal vascular function, and disequilibrium in its production can lead to diabetic retinopathy (DR). Genetic polymorphisms of eNOS gene have been suggested to play a role in nitric oxide (NO) abnormalities which may contribute to th...

journal_title：Acta diabetologica

authors： Cheema BS,kohli HS,Sharma R,Bhansali A,Khullar M

更新日期：2012-12-01 00:00:00

abstract：:Cytomegalovirus (CMV) infects 40 % of the world population and has been suggested to be associated with diabetes; however, no prospective study has ever examined diabetes mortality associated with the infection. A cohort of 14,404 non-diabetic adult participants aged 17-90 years from the Third National Health and Nutr...

journal_title：Acta diabetologica

authors： Mendy A,Gasana J,Vieira ER,Diallo H

更新日期：2014-10-01 00:00:00

abstract：AIMS:Haptoglobin (Hp) genotype 2-2 increases cardiovascular diabetes complications. In type 2 diabetes, α-tocopherol was shown to lower cardiovascular risk in Hp 2-2, potentially through HDL function improvements. Similar type 1 diabetes data are lacking. We conducted a randomized crossover pilot of α-tocopherol supple...

journal_title：Acta diabetologica

authors： Costacou T,Levy AP,Miller RG,Snell-Bergeon J,Asleh R,Farbstein D,Fickley CE,Pambianco G,de la Vega R,Evans RW,Orchard TJ

更新日期：2016-04-01 00:00:00

abstract：:We determined in non-diabetic persons the risk of fasting and non-fasting glucose levels for pre-diabetes, diabetes, and coronary heart disease (CHD), including the roles of serum C-reactive protein (CRP) and HDL cholesterol, and delineated risk profiles of the pre-diabetic states. Over 7¼ years, 2,619 middle-aged Tur...

journal_title：Acta diabetologica

authors： Onat A,Can G,Çiçek G,Ayhan E,Doğan Y,Kaya H

更新日期：2013-08-01 00:00:00

abstract：AIMS:Maternal type 2 diabetes (T2D) can result in adverse pathological outcomes to both the mother and fetus. The present study aimed to investigate the pathological effects of maternal T2D on the gene expression patterns and functions of fetal human umbilical vein endothelial cells (HUVECs), a representative of fetal ...

journal_title：Acta diabetologica

authors： Sultan S

更新日期：2019-01-01 00:00:00

abstract：:Insulin resistance is a major factor in the pathogenesis of type 2 diabetes mellitus (T2DM) and is related to the fatty acid profile of the plasma membranes. The purpose of the present study was to investigate fatty acid composition and cholesterol content of cell membranes in patients with type 2 diabetes and, thus, ...

journal_title：Acta diabetologica

authors： Bakan E,Yildirim A,Kurtul N,Polat MF,Dursun H,Cayir K

更新日期：2006-12-01 00:00:00

abstract：:We have measured protein phosphatase (PP) activity in crude homogenates as well as in the total 105.000 x g supernatant and precipitate fractions from normal rat pancreatic islets. On the basis of the inhibition produced by either 1 nM or 1 microM okadaic acid, both PP1 and PP2A activity were present in crude islet ho...

journal_title：Acta diabetologica

authors： Gagliardino JJ,Rossi PF,García ME

更新日期：1997-03-01 00:00:00

abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

journal_title：Acta diabetologica

authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

更新日期：2020-04-01 00:00:00

abstract：:The aim of the study is to evaluate the prevalence and incidence of myocardial dysfunction (MD) and heart failure (HF) in long-lasting (≥10 years) type 1 diabetes without cardiovascular disorders or with hypertension or coronary heart disease (CHD). The study included 1,685 patients with type 1 diabetes (mean baseline...

journal_title：Acta diabetologica

authors： Konduracka E,Cieslik G,Galicka-Latala D,Rostoff P,Pietrucha A,Latacz P,Gajos G,Malecki MT,Nessler J

更新日期：2013-08-01 00:00:00

abstract：:Hyperglycaemia caused by stress and inflammation is common during critical illness. We hypothesised that a latent glucose metabolism disturbance contributes to development of hyperglycaemia and that those patients have increased risk for diabetes. We included patients with sepsis, acute coronary syndrome and acute hea...

journal_title：Acta diabetologica

authors： Gornik I,Vujaklija A,Lukić E,Madžarac G,Gašparović V

更新日期：2010-12-01 00:00:00

abstract：AIMS:Type 2 diabetes (T2D) is a metabolic disorder requiring intensive self-care to maintain optimal glycemic control. Sleep disturbance is common in T2D patients and likely impairs glycemic control. Our aim was to examine the relationship between sleep disturbance and self-care in adults with T2D. METHODS:This study ...

journal_title：Acta diabetologica

authors： Zhu B,Quinn L,Kapella MC,Bronas UG,Collins EG,Ruggiero L,Park CG,Fritschi C

更新日期：2018-09-01 00:00:00

abstract：:Diabetes mellitus is an independent risk factor for falling, particularly in the elderly. Due to chronic hyperglycemia and hyperinsulinemia patients with diabetes mellitus may have neurological deficits as peripheral neuropathy that is a debilitating micro-vascular complication affecting the proximal and distal periph...

journal_title：Acta diabetologica

authors： Gioacchini FM,Albera R,Re M,Scarpa A,Cassandro C,Cassandro E

更新日期：2018-12-01 00:00:00

abstract：:To examine longitudinally the effect of diabetes on bone structure and metabolism, we measured bone mineral density (BMD) and turnover markers in 26 type 1 (mean age 49 years) and 27 type 2 (mean age 65 years) diabetic patients without known osteoporosis from a community-based sample at baseline and 5 years later. In ...

journal_title：Acta diabetologica

authors： Hamilton EJ,Rakic V,Davis WA,Paul Chubb SA,Kamber N,Prince RL,Davis TM

更新日期：2012-04-01 00:00:00

abstract：:The effect of sucrose in the diet of children and adolescents with type I diabetes on long-term metabolic control was studied. For a mean observation period of 83 (range 42-127) days, a diet containing 5% of total calories as refined sugar was recommended to 11 children (group A, mean age 15.0, SD 5.4 years), while an...

journal_title：Acta diabetologica

authors： Schwingshandl J,Rippel S,Unterluggauer M,Borkenstein M

更新日期：1994-12-01 00:00:00

abstract：:Anti-myeloperoxidase (anti-MPO) antibodies were detected in 34 of 88 (38%) patients with type 1 diabetes mellitus but in only 3 of 55 (5.7%) healthy subjects and in 4 of 20 patients with autoimmune disease. Specificity of anti-MPO antibodies was assessed by MPO inhibition studies. No relationship was found between the...

journal_title：Acta diabetologica

authors： Accardo-Palumbo A,Triolo G,Giardina E,Carbone MC,Ferrante A,Triolo G

更新日期：1996-07-01 00:00:00

abstract：AIMS:To examine the relationships between type 2 diabetes (T2D) status, glycemic control, and T2D duration with magnetic resonance imaging (MRI)-derived neuroimaging measures in European Americans from the Diabetes Heart Study (DHS) Mind cohort. METHODS:Relationships were examined using marginal models with generalize...

journal_title：Acta diabetologica

authors： Raffield LM,Cox AJ,Freedman BI,Hugenschmidt CE,Hsu FC,Wagner BC,Xu J,Maldjian JA,Bowden DW

更新日期：2016-06-01 00:00:00

abstract：:(31)P-magnetic resonance spectroscopy ((31)P-MRS) is a non-invasive tool to study high-energy phosphate (HEP) metabolism. We evaluate whether 31P-MRS can detect early changes in kidney HEP metabolism during a 6-month trial with Valsartan. Twenty consecutive stable and normotensive kidney-transplanted patients were enr...

journal_title：Acta diabetologica

authors： Fiorina P,Bassi R,Gremizzi C,Vergani A,Caldara R,Mello A,Del Maschio A,De Cobelli F,Perseghin G,Secchi A

更新日期：2012-12-01 00:00:00

abstract：:Autoantibodies to zinc transporter 8 (ZnT8A) are a powerful diagnostic or predictive marker in type 1 diabetes. However, the widely used current ZnT8A radioligand binding assay (RBA) has proved to be difficult for many laboratories to implement. The aim of this study was the development and characterization of the per...

journal_title：Acta diabetologica

authors： Kawasaki E,Tanaka M,Miwa M,Abiru N,Kawakami A

更新日期：2014-01-01 00:00:00

abstract：AIMS:This study aimed to assess islet insulin secretion and insulin resistance in Chinese patients with latent autoimmune diabetes in adults (LADA). METHODS:Twelve patients with LADA, 10 with type 1 diabetes mellitus (T1DM), 10 with type 2 diabetes mellitus (T2DM), and 10 nondiabetic healthy controls (HCs) were includ...

journal_title：Acta diabetologica

authors： Yang L,Liu X,Liang H,Cheng Y,Huang G,Zhou Z

更新日期：2019-11-01 00:00:00

abstract：AIMS:Observational studies indicated that resting heart rate (RHR) was associated with diabetes mellitus (DM) risk; however, it remains unclear whether the association between RHR and DM is causal. We aimed to examine whether there was causal association of RHR with DM risk. METHODS:A prospective study including 16,20...

journal_title：Acta diabetologica

authors： Long T,Wang J,Han X,Wang F,Hu H,Yu C,Yuan J,Yao P,Wei S,Wang Y,Liang Y,Miao X,Zhang X,Guo H,Zheng D,Tang Y,Yang H,Huang S,He M

更新日期：2019-09-01 00:00:00

abstract：AIMS:To assess the time-dependent effect of sleep quality on diabetes and coronary artery disease (CAD) incidence among young adults. METHODS:Incident rates of diabetes and CAD during a mean follow-up of 6.4 ± 4.1 years were assessed among 26,023 men (mean age 30.9 ± 5.6 years) of the Metabolic Lifestyle and Nutrition...

journal_title：Acta diabetologica

authors： Twig G,Shina A,Afek A,Derazne E,Tzur D,Cukierman-Yaffe T,Shechter-Amir D,Gerstein HC,Tirosh A

更新日期：2016-04-01 00:00:00

abstract：:In the perfused pancreas of adult rats that were injected with streptozotocin (STZ) during the neonatal period, the release of insulin caused by glucose is more severely affected than that evoked by other secretagogues. We have now examined whether a comparable situation prevails in vivo. In anesthetised rats, the 0-1...

journal_title：Acta diabetologica

authors： Vicent D,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：1994-09-01 00:00:00