当前位置： SCI文献检索 > ACTA DIABETOLOGICA期刊下所有文献 > Fasting, non-fasting glucose and HDL dysfunction in risk of pre-diabetes, diabetes, and coronary disease in non-diabetic adults.

Fasting, non-fasting glucose and HDL dysfunction in risk of pre-diabetes, diabetes, and coronary disease in non-diabetic adults.

Abstract：

:We determined in non-diabetic persons the risk of fasting and non-fasting glucose levels for pre-diabetes, diabetes, and coronary heart disease (CHD), including the roles of serum C-reactive protein (CRP) and HDL cholesterol, and delineated risk profiles of the pre-diabetic states. Over 7¼ years, 2,619 middle-aged Turkish adults free of diabetes and CHD were studied prospectively. Using different serum glucose categories including impaired fasting glucose (IFG, 6.1-6.97 mmol/L) and impaired glucose tolerance (IGT), outcomes were analyzed by Cox regression. IFG was identified at baseline in 112 and IGT in 33 participants. Metabolic syndrome components distinguished individuals with IFG from those with normoglycemia. Participants with IGT tended to differ from adults in normal postprandial glucose categories in regard to high levels of triglycerides, apoA-I, and CRP. Diabetes risk, adjusted for sex, age, waist circumference, CRP, and HDL cholesterol, commenced at a fasting 5.6-6.1 mmol/L threshold, was fourfold at levels 6.1-6.97 mmol/L. Optimal glucose values regarding CHD risk were 5.0-6.1 mmol/L. Fasting and postprandial glucose values were not related to CHD risk in men; IGT alone predicted risk in women (HR 3.74 [1.16;12.0]), independent of age, systolic blood pressure, non-HDL cholesterol, waist circumference, smoking status, and CRP. HDL cholesterol was unrelated to the development of IFG, IGT, and diabetes, while CRP elevation independently predicted the development of diabetes. IGT independently predicts CHD risk, especially in women. HDL dysfunction associated with low-grade inflammation is a co-determinant of pre-diabetic states and their progression to diabetes.

journal_name

Acta Diabetol

journal_title

Acta diabetologica

authors

Onat A,Can G,Çiçek G,Ayhan E,Doğan Y,Kaya H

doi

10.1007/s00592-011-0313-x

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

519-28

issue

4

eissn

0940-5429

issn

1432-5233

journal_volume

50

pub_type

杂志文章

相关文献

ACTA DIABETOLOGICA文献大全
  • Lack of gender difference in acetazolamide-induced cerebral vasomotor reactivity in patients suffering from type-1 diabetes mellitus.

    abstract：:The aim of the present work was to investigate the impact of gender on resting cerebral blood flow velocity and cerebrovascular reserve capacity among diabetic patients. Middle cerebral artery mean blood flow velocity (MCAV) was measured in 72 patients suffering from type 1 diabetes mellitus at rest and 5, 10, 15 and ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s005920170006

    authors： Fülesdi B,Limburg M,Oláh L,Bereczki D,Csiba L,Kollár J

    更新日期：2001-01-01 00:00:00

  • Decreases in Raf-1 levels in galactosaemic lens epithelial cells are partially reversed by myo-inositol.

    abstract：:Changes in the amounts and localization of protein kinase C (PKC) isoforms occur in galactosaemic lens epithelial cells. A link between PKC changes and myo-inositol depletion has been suggested. Raf-1, a component of a Ras pathway, is a substrate for PKC. Raf-1 levels were measured in galactosaemic lens epithelial cel...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s005920050119

    authors： Takemoto DJ

    更新日期：1998-10-01 00:00:00

  • Impact of sildenafil-containing ointment on wound healing in healthy and experimental diabetic rats.

    abstract：AIM:The study evaluated the effect of different concentrations of sildenafil-containing ointment on wound healing in healthy and streptozotocin (STZ)-induced diabetic rats. METHODS:A total of 108 Sprague Dawley male rats aged 5 months were randomly divided into two groups: healthy and diabetes-inducing rats. Following...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-020-01562-0

    authors： Abu Dayyih W,Abu Rayyan W,Al-Matubsi HY

    更新日期：2020-11-01 00:00:00

  • Failure of glycated hemoglobin drop after continuous subcutaneous insulin infusion initiation may indicate patients who discontinue: a 4-year follow-up study in children and adolescents with type 1 diabetes.

    abstract：:Continuous subcutaneous insulin infusion (CSII) is effective and safe in children and adults with type 1 diabetes. Notwithstanding, some patients decide to discontinue using CSII. We evaluated the discontinuation rate, and its related factors, in a large group of children and adolescents with type 1 diabetes using CSI...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s00592-011-0344-3

    authors： Lombardo F,Scaramuzza AE,Iafusco D

    更新日期：2012-12-01 00:00:00

  • Vasoactive intestinal polypeptide increases whole pancreatic blood flow but does not affect islet blood flow in the rat.

    abstract：:To evaluate the effects of vasoactive intestinal peptide (VIP) on whole pancreatic blood flow and islet blood flow in the rat, anaesthetized adult rats were injected intravenously for 90 s with VIP (500 ng/kg body weight). Immediately after the injection, the whole pancreatic and islet blood flows were measured with a...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/BF00570545

    authors： Jansson L

    更新日期：1994-06-01 00:00:00

  • Oxidative stress in kidney and liver of alloxan-induced diabetic rabbits: effect of repaglinide.

    abstract：:The aim of this study was to analyse the effect of the new oral antidiabetic drug repaglinide on antioxidant factors and lipid peroxidation in tissues of alloxan-induced diabetic rabbits after 4 and 8 weeks treatment. The activity of superoxide dismutase (diabetic vs. control values, mean+/-S.E.M., p<0.05) in diabetic...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-005-0182-2

    authors： Gumieniczek A

    更新日期：2005-06-01 00:00:00

  • Modulation of gut microbiota contributes to effects of intensive insulin therapy on intestinal morphological alteration in high-fat-diet-treated mice.

    abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-019-01436-0

    authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

    更新日期：2020-04-01 00:00:00

  • A five-year prospective study of bone mineral density in men and women with diabetes: the Fremantle Diabetes Study.

    abstract：:To examine longitudinally the effect of diabetes on bone structure and metabolism, we measured bone mineral density (BMD) and turnover markers in 26 type 1 (mean age 49 years) and 27 type 2 (mean age 65 years) diabetic patients without known osteoporosis from a community-based sample at baseline and 5 years later. In ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-011-0324-7

    authors： Hamilton EJ,Rakic V,Davis WA,Paul Chubb SA,Kamber N,Prince RL,Davis TM

    更新日期：2012-04-01 00:00:00

  • Total bilirubin is inversely associated with metabolic syndrome but not a risk factor for metabolic syndrome in Japanese men and women.

    abstract：:Serum total bilirubin (TB) is a potent antioxidant and inversely associated with metabolic syndrome (MetS) in Asian populations. However, there has been no study which is aimed to investigate whether TB is a risk factor for MetS or not. We investigated cross-sectional and longitudinal associations between TB and MetS ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-012-0447-5

    authors： Oda E,Aizawa Y

    更新日期：2013-06-01 00:00:00

  • Investigation of miRNA-binding site variants and risk of gestational diabetes mellitus in Chinese pregnant women.

    abstract：AIMS:Emerging evidence suggested genetic factor attributed as a major determinant for the complex pathogenic mechanism of gestational diabetes mellitus (GDM), but the related genetic study was limited. We aimed to investigate the impact of polymorphisms in miRNA-binding sites (miR-binding SNPs) on the risk of GDM in Ch...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-017-0969-y

    authors： Wang X,Li W,Ma L,Ping F,Liu J,Wu X,Mao J,Wang X,Nie M

    更新日期：2017-03-01 00:00:00

  • The association of PTPN22 rs2476601 polymorphism and CTLA-4 rs231775 polymorphism with LADA risks: a systematic review and meta-analysis.

    abstract：:Although the polymorphisms of PTPN22 and the variants of CTLA-4 have been reported to be the susceptibility genes, which increased risk of latent autoimmune diabetes in adults (LADA), the results remained inconclusive. The aim of this meta-analysis was to evaluate the association between the polymorphisms of two genes...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00592-014-0613-z

    authors： Dong F,Yang G,Pan HW,Huang WH,Jing LP,Liang WK,Zhang N,Zhang BH,Wang M,Liu Y,Zhang LJ,Zhang SH,Li H,Chen C,Nie LH,Jing CX

    更新日期：2014-10-01 00:00:00

  • Strong evidence of sexual dimorphic effect of adiposity excess on insulin sensitivity.

    abstract：AIMS:Our aims were to investigate in several large samples, with a wide range of adiposity, whether: (1) the effect of BMI on insulin sensitivity is different between sexes; (2) also waist circumference plays a sex-specific role on insulin sensitivity; and (3) serum adiponectin and resistin are mediators of such sex-di...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-015-0804-2

    authors： Marucci A,Menzaghi C,Copetti M,Vinciguerra F,Baratta R,Salvemini L,Morini E,Frittitta L,Di Paola R,Trischitta V

    更新日期：2015-10-01 00:00:00

  • The 16-year incidence, progression and regression of diabetic retinopathy in a young population-based Danish cohort with type 1 diabetes mellitus: The Danish cohort of pediatric diabetes 1987 (DCPD1987).

    abstract：:The aim was to investigate the long-term incidence of proliferative diabetic retinopathy (PDR), and progression and regression of diabetic retinopathy (DR) and associated risk factors in young Danish patients with Type 1 diabetes mellitus. In 1987-89, a pediatric cohort involving approximately 75 % of all children wit...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-013-0527-1

    authors： Broe R,Rasmussen ML,Frydkjaer-Olsen U,Olsen BS,Mortensen HB,Peto T,Grauslund J

    更新日期：2014-01-01 00:00:00

  • Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study.

    abstract：:The objective of the study was to evaluate the association between infectious diseases and other events pertaining to childhood medical history and type 1 diabetes. A case-control study was carried out, taking as cases 159 type 1 diabetic patients (0-29 years) recorded from 1988 to 2000 within the population registry ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-007-0235-9

    authors： Tenconi MT,Devoti G,Comelli M,Pinon M,Capocchiano A,Calcaterra V,Pretti G,Pavia T1DM Registry Group.

    更新日期：2007-03-01 00:00:00

  • Role of the PKCβII/JNK signaling pathway in acute glucose fluctuation-induced apoptosis of rat vascular endothelial cells.

    abstract：AIMS:The purpose of this study was to investigate the mechanism of vascular endothelial cell apoptosis induced by acute blood glucose fluctuation. METHODS:Thirty rats were assigned to three groups: normal saline (SAL group), constant high glucose (CHG group) and acute blood glucose fluctuation (AFG) group. Other forty...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-017-0999-5

    authors： Wu N,Shen H,Wang Y,He B,Zhang Y,Bai Y,Du R,Du Q,Han P

    更新日期：2017-08-01 00:00:00

  • Body composition changes following laparoscopic gastric banding for morbid obesity.

    abstract：:Most reports of outcome following obesity surgery report weight and co-morbidity changes only. We studied body composition changes in 17 adult patients (15 F, 2 M, age 43+/-2 years, range 28-58 years), with morbid obesity (initial BMI 40.4+/-4.9 kg/m(2), range 34.7-48.8) who were managed surgically by laparoscopically...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-003-0083-1

    authors： Strauss BJ,Marks SJ,Growcott JP,Stroud DB,Lo CS,Dixon JB,O'Brien PE

    更新日期：2003-10-01 00:00:00

  • GAD 65 antibody but not ICA positivity in adult-onset diabetic patients is associated with early progression to clinical insulin dependency.

    abstract：:Correct classification of diabetic patients in adulthood at the time of diagnosis is often difficult. Some may be initially diagnosed as having non-insulin-dependent diabetes mellitus and be treated with diet and/or oral hypoglycaemic agents (OHA) but later require insulin treatment. Islet cell antibodies and antibodi...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/BF00571567

    authors： Hatziagelaki E,Jaeger C,Maeser E,Bretzel RG,Federlin K

    更新日期：1996-12-01 00:00:00

  • Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats.

    abstract：:The objective is to assess the effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar rats, 8-week-old, were categorized into four groups, which were the control (n = 9), diabetes (n = 9), infliximab-treated diabetes (n = 10), and FR167653-treated diabetes (n = 9) groups...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-007-0007-6

    authors： Moriwaki Y,Inokuchi T,Yamamoto A,Ka T,Tsutsumi Z,Takahashi S,Yamamoto T

    更新日期：2007-12-01 00:00:00

  • The use of continuous density gradients for the assessment of islet and exocrine tissue densities and islet purification.

    abstract：:The purification of large numbers of human pancreatic islets remains one of the limiting factors in islet transplantation. This paper describes and validates a method for accurately and reproducibly determining the density of islets and exocrine tissue in pancreatic digest on the basis of their isopycnic distribution ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/BF00572864

    authors： Robertson GS,Chadwick DR,Contractor H,James RF,Bell PR,London NJ

    更新日期：1993-01-01 00:00:00

  • Glycation of insulin results in reduced biological activity in mice.

    abstract：:Bovine insulin was glycated by in vitro incubation with 20-220 mM D-glucose for 1-48 h. The percentage of glycation was dependent on time, glucose concentration, temperature and pH, attaining values up to 28%. Glucose-lowering activities of glycated and control (non-glycated) insulin preparations were assessed in mice...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s005920050086

    authors： Abdel-Wahab YH,O'Harte FP,Boyd AC,Barnett CR,Flatt PR

    更新日期：1997-12-01 00:00:00

  • Screening and diagnosis of gestational diabetes in India: a systematic review and meta-analysis.

    abstract：AIMS:Although diabetes is rapidly increasing in India, there is no national consensus on best practices for screening, diagnosis, and management of gestational diabetes mellitus (GDM). The goal of this study was to systematically review the literature for studies reporting the prevalence and screening and diagnostic me...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s00592-018-1131-1

    authors： Li KT,Naik S,Alexander M,Mathad JS

    更新日期：2018-06-01 00:00:00

  • Undiagnosed diabetes and impaired glucose regulation in adult Ghanaians using the ADA and WHO diagnostic criteria.

    abstract：:Fasting glucose and oral glucose tolerance test (OGTT) criteria for glucose homeostasis were compared in a cross-sectional cluster, community study in Accra, Ghana. A total of 4636 subjects without prior diagnosis of diabetes had fasting plasma glucose, 2-hour OGTT and measurement of cardiovascular risk factors. Mean ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s005920200006

    authors： Amoah AG

    更新日期：2002-04-01 00:00:00

  • Mortality in Asian Indians with Charcot's neuroarthropathy: a nested cohort prospective study.

    abstract：AIMS:We studied mortality in individuals of diabetes with or without Charcot neuroarthropathy (CN). METHODS:People attending diabetic foot care facility with CN of foot (Cohort 1) were prospectively evaluated. Details pertaining to the duration of diabetes, microvascular and macrovascular complications, foot ulcer, am...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,评审

    doi：10.1007/s00592-019-01376-9

    authors： Chaudhary S,Bhansali A,Rastogi A

    更新日期：2019-12-01 00:00:00

  • Using the Internet-based upload blood glucose monitoring and therapy management system in patients with type 1 diabetes.

    abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00592-013-0510-x

    authors： Shalitin S,Ben-Ari T,Yackobovitch-Gavan M,Tenenbaum A,Lebenthal Y,de Vries L,Phillip M

    更新日期：2014-04-01 00:00:00

  • Preserved incretin effect in type 1 diabetic patients with end-stage nephropathy treated by combined heterotopic pancreas and kidney transplantation.

    abstract：:Insulin secretion is stimulated better by oral than by intravenous glucose (incretin effect). The contribution of the autonomic nervous system to the incretin effect after oral glucose in humans is unclear. We therefore examined nine type 1 diabetic (insulin-dependent) patients with end-stage nephropathy, studied afte...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/BF00572873

    authors： Nauck MA,Büsing M,Orskov C,Siegel EG,Talartschik J,Baartz A,Baartz T,Hopt UT,Becker HD,Creutzfeldt W

    更新日期：1993-01-01 00:00:00

  • Errors in insulin treatment management and risk of lipohypertrophy.

    abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-017-1066-y

    authors： Pozzuoli GM,Laudato M,Barone M,Crisci F,Pozzuoli B

    更新日期：2018-01-01 00:00:00

  • Myocardial dysfunction and chronic heart failure in patients with long-lasting type 1 diabetes: a 7-year prospective cohort study.

    abstract：:The aim of the study is to evaluate the prevalence and incidence of myocardial dysfunction (MD) and heart failure (HF) in long-lasting (≥10 years) type 1 diabetes without cardiovascular disorders or with hypertension or coronary heart disease (CHD). The study included 1,685 patients with type 1 diabetes (mean baseline...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-013-0455-0

    authors： Konduracka E,Cieslik G,Galicka-Latala D,Rostoff P,Pietrucha A,Latacz P,Gajos G,Malecki MT,Nessler J

    更新日期：2013-08-01 00:00:00

  • I fear COVID but diabetic foot (DF) is worse: a survey on patients' perception of a telemedicine service for DF during lockdown.

    abstract：AIMS:To evaluate the patients' perceptions of telemedicine visits during COVID-19 lockdown and their level of anxiety about COVID and diabetic foot (DF). METHODS:In May 2020, we contacted by phone all the patients who underwent in March and April to remote monitoring visits for DF during the lockdown for COVID-19, wit...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s00592-020-01653-y

    authors： Iacopi E,Pieruzzi L,Goretti C,Piaggesi A

    更新日期：2021-01-13 00:00:00

  • Risk of cancer in patients treated with dipeptidyl peptidase-4 inhibitors: an extensive meta-analysis of randomized controlled trials.

    abstract：AIMS:Observational studies and meta-analyses of randomized trials on dipeptidyl peptidase-4 inhibitors (DPP4i) reported discordant results on the risk of malignancies with this class of drugs. Aim of the present meta-analysis is the assessment of the effect of DPP4i treatment on the incidence of different types of canc...

    journal_title：Acta diabetologica

    pub_type： 杂志文章,meta分析

    doi：10.1007/s00592-020-01479-8

    authors： Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

    更新日期：2020-06-01 00:00:00

  • Type 2 diabetes mellitus and osteopenia: is there an association?

    abstract：:We report the results of bone mineral density (BMD) measurements in type 2 diabetic patients, in comparison to healthy controls. In this prospective study, a total of 277 subjects (aged 30-60 years) with type 2 diabetes mellitus, outpatients at the Cukurova Medical School Hospital, were evaluated for BMD at L(1)-L(4) ...

    journal_title：Acta diabetologica

    pub_type： 杂志文章

    doi：10.1007/s005920300014

    authors： Sert M,Tetiker T,Kirim S,Soyupak S,Canataroğlu A,Koçak M

    更新日期：2003-06-01 00:00:00