Type 2 diabetes mellitus and osteopenia: is there an association?

abstract：:Although reactive oxygen species (ROS) contribute to glucose intolerance induced by the renin-angiotensin system (RAS) is well documented, the role of the newly discovered pathway of RAS, angiotensin (Ang)-(1-7)/Mas axis, in this process remains unknown. Here, we examined the effect of Ang-(1-7) on oxidative stress an...

journal_title：Acta diabetologica

authors： Liu C,Lv XH,Li HX,Cao X,Zhang F,Wang L,Yu M,Yang JK

更新日期：2012-08-01 00:00:00

abstract：:Although the effects of sex, ageing, height, race, and current and past health on pulmonary function tests have been described, only non-significant associations have been observed between body weight and lung function among healthy persons after having accounted for the effects of age and height. However, few studies...

journal_title：Acta diabetologica

authors： Maiolo C,Mohamed EI,Carbonelli MG

更新日期：2003-10-01 00:00:00

abstract：:Preliminary evidence from trials with the HMG-CoA reductase inhibitors (statins), simvastatin and pravastatin, suggests that aggressive treatment of diabetic dyslipidaemia will reduce coronary events. Questions regarding the prevention of cardiovascular events in diabetic patients are now being addressed in prospectiv...

journal_title：Acta diabetologica

authors： Crespin SR

更新日期：2001-01-01 00:00:00

abstract：AIMS:To assess the metabolic health of obese and non-obese women at high GDM risk 5 years postpartum. METHODS:This is a secondary analysis of the 5-year follow-up of the RADIEL GDM prevention study including 333 women at high GDM risk (BMI ≥ 30 kg/m2 and/or previous GDM). Five years postpartum metabolic health was ass...

journal_title：Acta diabetologica

authors： Huvinen E,Eriksson JG,Koivusalo SB,Grotenfelt N,Tiitinen A,Stach-Lempinen B,Rönö K

更新日期：2018-05-01 00:00:00

abstract：AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...

journal_title：Acta diabetologica

authors： Luo W,Yu Y,Wang H,Liu K,Wang Y,Huang M,Xuan C,Li Y,Qi J

更新日期：2020-12-01 00:00:00

abstract：:The recent efforts in the study of fetal compartments could help us to a better recognition of the proper fetal growth and well being. Fat content correlates directly with energy stores. Fat mass and lean body mass is often used in the nutritional assessment of the individual. Moreover chromosomal abnormalities may be...

journal_title：Acta diabetologica

authors： Valensise H,Larciprete G,Arduini D,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：:Diabetes cardiomyopathy is a specific form of cardiac disease characteristic for diabetic patients. Development of echocardiography enabled diagnosis of diabetic cardiomyopathy significantly before the occurrence of heart failure. Previously was believed that left ventricular (LV) diastolic dysfunction represents the ...

journal_title：Acta diabetologica

authors： Tadic M,Cuspidi C,Calicchio F,Grassi G,Mancia G

更新日期：2020-09-01 00:00:00

abstract：:Bovine insulin was glycated by in vitro incubation with 20-220 mM D-glucose for 1-48 h. The percentage of glycation was dependent on time, glucose concentration, temperature and pH, attaining values up to 28%. Glucose-lowering activities of glycated and control (non-glycated) insulin preparations were assessed in mice...

journal_title：Acta diabetologica

authors： Abdel-Wahab YH,O'Harte FP,Boyd AC,Barnett CR,Flatt PR

更新日期：1997-12-01 00:00:00

abstract：:The original report on the microencapsulation of islets of Langerhans used sodium alginate and poly-L-lysine (PLL) to form the capsules. Although several alternative materials have subsequently been used with vary-mg degrees of success, it is those studies using islets encapsulated in alginate-PLL-alginate which are r...

journal_title：Acta diabetologica

authors： Clayton HA,James RF,London NJ

更新日期：1993-01-01 00:00:00

abstract：:Cyclosporin and methotrexate administration induces remission of type 1 diabetes mellitus. Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). Its usefulness was limited by its toxicity. Since methotrexate (mtx) and cyclo synergistically inhibit ...

journal_title：Acta diabetologica

authors： Sobel DO,Henzke A,Abbassi V

更新日期：2010-09-01 00:00:00

abstract：:Recent studies have reported that elevated proinsulin levels are indicative of an increased cardiovascular risk. Renal proximal tubular cells represent a major site for the metabolism of insulin-like hormones after glomerular filtration into the tubular lumen. To determine the binding and degradation of proinsulin in ...

journal_title：Acta diabetologica

authors： Jehle PM,Fussgänger RD,Stracke S,Grunewald RW,Keller F

更新日期：1996-07-01 00:00:00

abstract：:Obesity, insulin resistance (IR), and progressive decline in pancreatic β-cell function are major features of type 2 diabetes mellitus (T2DM). Altered adipokines contribute to obesity-induced IR. Hence understanding of adipokines' relation to obesity and glycemic control could be useful to improve disease outcomes. We...

journal_title：Acta diabetologica

authors： El-Mesallamy HO,Hamdy NM,Sallam AA

更新日期：2013-10-01 00:00:00

abstract：:Administration of exogenous insulin for the treatment of diabetes is often accompanied by the development of insulin antibodies (IA). These antibodies may affect the patient's requirement for insulin by acting as an insulin binding reservoir. The improvement of insulin purification in the 1970s and the development of ...

journal_title：Acta diabetologica

authors： Oak S,Phan TH,Gilliam LK,Hirsch IB,Hampe CS

更新日期：2010-06-01 00:00:00

abstract：AIMS:High glycemic variability (GV) is the major indication for islet transplantation (IT) in patients with type 1 diabetes (T1D). The actual criteria used to assess graft function do not consider GV improvement. Our study aimed to describe GV indices' evolution in T1D patients who benefited from IT during the TRIMECO ...

journal_title：Acta diabetologica

authors： Jalbert M,Zheng F,Wojtusciszyn A,Forbes F,Bonnet S,Skaare K,Benhamou PY,Lablanche S,TRIMECO Study Group.

更新日期：2020-03-01 00:00:00

abstract：AIM:To identify the potential metabolite markers in diabetic retinopathy (DR) by using gas chromatography coupled with time-of-flight mass spectrometry (GC-TOFMS). METHODS:GC-TOFMS spectra were acquired from vitreous and aqueous humor (AH) samples of patients with DR and non-diabetic participants. Comparative analysis...

journal_title：Acta diabetologica

authors： Wang H,Fang J,Chen F,Sun Q,Xu X,Lin SH,Liu K

更新日期：2020-01-01 00:00:00

abstract：:Although the polymorphisms of PTPN22 and the variants of CTLA-4 have been reported to be the susceptibility genes, which increased risk of latent autoimmune diabetes in adults (LADA), the results remained inconclusive. The aim of this meta-analysis was to evaluate the association between the polymorphisms of two genes...

journal_title：Acta diabetologica

authors： Dong F,Yang G,Pan HW,Huang WH,Jing LP,Liang WK,Zhang N,Zhang BH,Wang M,Liu Y,Zhang LJ,Zhang SH,Li H,Chen C,Nie LH,Jing CX

更新日期：2014-10-01 00:00:00

abstract：:(31)P-magnetic resonance spectroscopy ((31)P-MRS) is a non-invasive tool to study high-energy phosphate (HEP) metabolism. We evaluate whether 31P-MRS can detect early changes in kidney HEP metabolism during a 6-month trial with Valsartan. Twenty consecutive stable and normotensive kidney-transplanted patients were enr...

journal_title：Acta diabetologica

authors： Fiorina P,Bassi R,Gremizzi C,Vergani A,Caldara R,Mello A,Del Maschio A,De Cobelli F,Perseghin G,Secchi A

更新日期：2012-12-01 00:00:00

abstract：:For many diabetic patients, years of blood glucose self-monitoring (SM) with readings taken several times daily is an inevitable aspect of insulin therapy. We investigated whether SM from abdominal skin might be an alternative to the established fingertip method. A total of 63 diabetic patients and 16 nondiabetic volu...

journal_title：Acta diabetologica

authors： Holstein A,Thiessen E,Kaufmann N,Plaschke A,Egberts EH

更新日期：2002-06-01 00:00:00

abstract：AIMS:Prognostic significance of apolipoproteins in diabetic retinopathy risk has not been well investigated. The aim of this study was to reveal the relationship between the risk of diabetic retinopathy and the levels of several apolipoproteins and their ratios in a 10-year prospective cohort. METHODS:A total of 1023 ...

journal_title：Acta diabetologica

authors： Zhang Q,Hu J,Hu Y,Ding Y,Zhu J,Zhuang C

更新日期：2018-07-01 00:00:00

abstract：AIMS:To evaluate the methodological quality of systematic reviews (SRs), and summarize evidence of important outcomes from dipeptidyl peptidase-4 inhibitors (DPP4-I) in treating type 2 diabetes mellitus (T2DM). METHODS:We included SRs of DPP4-I for the treatment of T2DM until January, 2018 by searching the Cochrane Li...

journal_title：Acta diabetologica

authors： Ling J,Ge L,Zhang DH,Wang YF,Xie ZL,Tian JH,Xiao XH,Yang KH

更新日期：2019-01-01 00:00:00

abstract：:Concentrations of soluble receptors for tumor necrosis factor (p55 and p75) strongly correlate with clinical stage and progression of infectious diseases, and may be useful in monitoring autoimmune diseases. However, the role of soluble TNF receptors in insulin-dependent diabetes mellitus (type 1 DM) is not clear. We ...

journal_title：Acta diabetologica

authors： Kulseng B,Vatten L,Espevik T

更新日期：1999-06-01 00:00:00

abstract：:Postreceptor insulin resistance was studied in liver, muscle and adipose tissue from NMRI mice of both sexes made diabetic by long-term fat-feeding. Intravenous glucose tolerance tests showed a combination of impaired glucose tolerance and increased plasma insulin concentrations consistent with insulin resistance and ...

journal_title：Acta diabetologica

authors： Hedeskov CJ,Capito K,Islin H,Hansen SE,Thams P

更新日期：1992-01-01 00:00:00

abstract：:A cross-sectional descriptive study was done on patients recently entered into the National Diabetes Registry in Eritrea where the prevalence was estimated to be 2.2% based on patient information in 2004. Of the 627 patients with diabetes, two thirds were type 2. Although type 1 had poorer control (42.9%) than type 2 ...

journal_title：Acta diabetologica

authors： Seyum B,Mebrahtu G,Usman A,Mufunda J,Tewolde B,Haile S,Kosia A,Negassi E

更新日期：2010-03-01 00:00:00

abstract：:Post-prandial hyperglycemia is considered a relevant therapeutic target in type 2 diabetic patients, and it could represent per se an independent risk factor for diabetic complications. Aim of the present systematic review is to collect and summarize evidence from observational studies on the relationship between post...

journal_title：Acta diabetologica

authors： Mannucci E,Monami M,Lamanna C,Adalsteinsson JE

更新日期：2012-08-01 00:00:00

abstract：AIMS:The aims of this study were: to develop new equations for predicting resting energy expenditure (REE) in obese Italian subjects according to body composition parameters; to compare them with predicted values estimated by other REE prediction equations; and to cross-validate our equations using a validation set coh...

journal_title：Acta diabetologica

authors： De Lorenzo A,Di Renzo L,Morini P,de Miranda RC,Romano L,Colica C

更新日期：2018-01-01 00:00:00

abstract：:This 64-week prospective cohort trial evaluated the effects of 20-mg oestradiol implants, replaced every 4 months, in healthy postmenopausal women aged 45-65 years. Of 20 implant and 14 control subjects who remained in the trial at 32 weeks, 13 implant and seven controls continued to 64 weeks, with no baseline differe...

journal_title：Acta diabetologica

authors： Hansen RD,Raja C,Baber RJ,Lieberman D,Allen BJ

更新日期：2003-10-01 00:00:00

abstract：AIM:High glucose-induced oxidative stress has been suggested as one of the mediators of endothelial damage in diabetes. The major endothelial protein, endoglin, has been found overexpressed in the vessels during pathological situations, but little is known about its relation to diabetic vascular complications. To clari...

journal_title：Acta diabetologica

authors： La Sala L,Pujadas G,De Nigris V,Canivell S,Novials A,Genovese S,Ceriello A

更新日期：2015-06-01 00:00:00

abstract：AIMS:Hyperreflective foci (HF), detected in the retina of diabetic patients, suggest the presence of microglial activation and migration, while controversies still remain for the origin of HF to be precursors of hard exudates. We investigated the presence of HF and their association with dyslipidemia in serous retinal ...

journal_title：Acta diabetologica

authors： Chung YR,Lee SY,Kim YH,Byeon HE,Kim JH,Lee K

更新日期：2020-07-01 00:00:00

abstract：AIM:The study evaluated the effect of different concentrations of sildenafil-containing ointment on wound healing in healthy and streptozotocin (STZ)-induced diabetic rats. METHODS:A total of 108 Sprague Dawley male rats aged 5 months were randomly divided into two groups: healthy and diabetes-inducing rats. Following...

journal_title：Acta diabetologica

authors： Abu Dayyih W,Abu Rayyan W,Al-Matubsi HY

更新日期：2020-11-01 00:00:00

abstract：AIMS:Genetic polymorphisms may contribute to platelet reactivity in diabetic patients; however, the information on their influence on long-term antiplatelet therapy is lacking. Our aim was to evaluate the role of previously described genetic variants and platelet reactivity on risk of all-cause mortality and cardiovasc...

journal_title：Acta diabetologica

authors： Milanowski L,Pordzik J,Janicki PK,Kaplon-Cieslicka A,Rosiak M,Peller M,Tyminska A,Ozieranski K,Filipiak KJ,Opolski G,Mirowska-Guzel D,Postula M

更新日期：2017-04-01 00:00:00