Undiagnosed diabetes and impaired glucose regulation in adult Ghanaians using the ADA and WHO diagnostic criteria.

abstract：AIMS:Medication adherence and persistence are important determinants of treatment success in type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis evaluated the real-world adherence, persistence, and in-class switching among patients with T2DM prescribed dipeptidyl peptidase-4 (DPP4) inhibitors. ME...

journal_title：Acta diabetologica

authors： Ogundipe O,Mazidi M,Chin KL,Gor D,McGovern A,Sahle BW,Jermendy G,Korhonen MJ,Appiah B,Ademi Z,De Bruin ML,Liew D,Ofori-Asenso R

更新日期：2021-01-01 00:00:00

abstract：:We hypothesize that type 2 diabetic patients with different phenotypes may show different response to incretin-based therapies. Therefore, we tested whether the presence of metabolic syndrome (MS) influences glycemic response to these drugs. We prospectively followed 211 patients, treated with the GLP-1 analog exenati...

journal_title：Acta diabetologica

authors： Fadini GP,de Kreutzenberg SV,Gjini R,Avogaro A

更新日期：2011-09-01 00:00:00

abstract：:Selective loss of capillary pericytes occurs early and specifically in diabetic retinopathy. We have investigated whether blood derivatives from patients with long-term type 1 (insulin-dependent) diabetes and no retinopathy differ from those with retinopathy and/or non-diabetic controls in their ability to stimulate D...

journal_title：Acta diabetologica

authors： Williams FM,Dosso AA,Kohner EM,Porta M

更新日期：1993-01-01 00:00:00

abstract：:The aim of this study was to evaluate lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes, and then to establish whether moderate doses of nonenzymatic antioxidant vitamin E play a role in the antioxidant defence system in diabetic pregnant rats and their offspring. The study group con...

journal_title：Acta diabetologica

authors： Kinalski M,Sledziewski A,Telejko B,Zarzycki W,Kinalska I

更新日期：2000-01-01 00:00:00

abstract：AIMS:The aim of our study was to estimate the overall rate of first hospitalizations for diabetic foot (DF) regardless of the outcome in amputations, as well as the mortality rate with their determinants in the period 2012-2016 in Piedmont Region in Italy. METHODS:The study included all the subjects registered in the ...

journal_title：Acta diabetologica

authors： Monge L,Gnavi R,Carnà P,Broglio F,Boffano GM,Giorda CB

更新日期：2020-02-01 00:00:00

abstract：AIMS:Glucose-dependent insulinotropic polypeptide (GIP) is released primarily from the proximal small intestine and glucagon-like peptide-1 (GLP-1) from the more distal small intestine and colon. Their relative importance to the incretin effect in health has been contentious in the past, although it now appears that GI...

journal_title：Acta diabetologica

authors： Marathe CS,Pham H,Marathe JA,Trahair LG,Huynh L,Wu T,Phillips LK,Rayner CK,Nauck MA,Horowitz M,Jones KL

更新日期：2020-05-01 00:00:00

abstract：:The aim of the study was to report the prevalence of obesity indices in individuals with diabetes and find out their association with diabetic retinopathy in the urban Indian population. Subjects (n = 1,414) were recruited from Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular Genetics Study (SN-DREAM...

journal_title：Acta diabetologica

authors： Raman R,Rani PK,Gnanamoorthy P,Sudhir RR,Kumaramanikavel G,Sharma T

更新日期：2010-09-01 00:00:00

abstract：:To determine the impact of glargine insulin therapy with different nutritional models on key parameters of diabetes including quality of life, behavior in children and adolescents with type 1 diabetes. Age, duration of diabetes, HbA1c, anthropometric data and episodes of severe hypoglycemia were taken from patients' c...

journal_title：Acta diabetologica

authors： Goksen D,Darcan S,Buyukinan M,Köse T,Erermis S,Coker M

更新日期：2008-03-01 00:00:00

abstract：:This study was aimed at the assessment of incidence of malignancies in type 2 diabetic patients treated with different sulphonylureas. A matched case-control study was performed. Cases were 195 diabetic patients aged 69.0 +/- 9.2 years who had an incident malignancy. Controls were 195 diabetic patients, unaffected by ...

journal_title：Acta diabetologica

authors： Monami M,Lamanna C,Balzi D,Marchionni N,Mannucci E

更新日期：2009-12-01 00:00:00

abstract：:Consistent with the postulated role of oxidative stress in the etiology of late diabetic complications, pharmacological interventions based on biological antioxidants have been suggested. The aim of the present study was to investigate the effect of dietary supplementation with the pyridoindole antioxidant stobadine o...

journal_title：Acta diabetologica

authors： Stefek M,Sotnikova R,Okruhlicova L,Volkovova K,Kucharska J,Gajdosik A,Gajdosikova A,Mihalova D,Hozova R,Tribulova N,Gvozdjakova A

更新日期：2000-01-01 00:00:00

abstract：:To study the immune response to glutamic acid decarboxylase (GAD) in insulin-dependent diabetes mellitus, monoclonal GAD antibodies after fusion of splenocytes from a nondiabetes-susceptible BALB/c mouse immunized with human recombinant GAD65 were generated. Of the 44 monoclonals, 35 are specific for the GAD65 isoform...

journal_title：Acta diabetologica

authors： Ziegler B,Schlosser M,Lühder F,Strebelow M,Augstein P,Northemann W,Powers AC,Ziegler M

更新日期：1996-09-01 00:00:00

abstract：AIMS:Type 1 diabetes is increasing in children leading more T1D young adults to adult healthcare settings. This change is experienced as a tear and results in a disengagement from specialist services. This study reports on an implementation of an effective and pioneering program of transition in North Africa. METHODS:...

journal_title：Acta diabetologica

authors： Essaddam L,Kallali W,Jemel M,Kandara H,Kammoun I,Hsairi M,Ben Salem L,Ben Becher S

更新日期：2018-11-01 00:00:00

abstract：:Cytomegalovirus (CMV) infects 40 % of the world population and has been suggested to be associated with diabetes; however, no prospective study has ever examined diabetes mortality associated with the infection. A cohort of 14,404 non-diabetic adult participants aged 17-90 years from the Third National Health and Nutr...

journal_title：Acta diabetologica

authors： Mendy A,Gasana J,Vieira ER,Diallo H

更新日期：2014-10-01 00:00:00

abstract：AIMS:Emerging evidence suggested genetic factor attributed as a major determinant for the complex pathogenic mechanism of gestational diabetes mellitus (GDM), but the related genetic study was limited. We aimed to investigate the impact of polymorphisms in miRNA-binding sites (miR-binding SNPs) on the risk of GDM in Ch...

journal_title：Acta diabetologica

authors： Wang X,Li W,Ma L,Ping F,Liu J,Wu X,Mao J,Wang X,Nie M

更新日期：2017-03-01 00:00:00

abstract：:The proinflammatory lysophosphatidic acid (LPA) is a potent activator of several transcriptional factors and signaling pathways and a potent modulator of genes involved in inflammation, angiogenesis and fibrosis. This study was conducted to measure the levels of LPA and LPA-producing enzymes, autotaxin (ATX) and acylg...

journal_title：Acta diabetologica

authors： Abu El-Asrar AM,Mohammad G,Nawaz MI,Siddiquei MM,Kangave D,Opdenakker G

更新日期：2013-06-01 00:00:00

abstract：:It usually takes several years (in some cases, decades) for predisposed individuals to move from the onset of type 1 or type 2 diabetes to the development of microalbuminuria, the first sign of diabetic nephropathy. This long, complication-free, period represents the best possible moment to start a successful preventi...

journal_title：Acta diabetologica

authors： Maestroni S,Zerbini G

更新日期：2018-11-01 00:00:00

abstract：:MicroRNAs (miRNAs) play a crucial role in the pathogenesis of type 2 diabetes (T2D); they regulate several metabolic pathways including insulin secretion, glucose homeostasis, so their potential as biomarkers of diagnosis and prognosis has became increasingly appreciated. In this study, we explore serum miRNA profiles...

journal_title：Acta diabetologica

authors： Yang Z,Chen H,Si H,Li X,Ding X,Sheng Q,Chen P,Zhang H

更新日期：2014-10-01 00:00:00

abstract：:In the present study, we investigated whether the ameliorating effect of aminoguanidine on diabetes-related proteinuria and nephropathy is associated with glomerular basement membrane heparan sulphate contents. STZ-induced diabetic rats developed proteinuria (at the tenth week: diabetic rats, 713 +/- 418 mg protein pe...

journal_title：Acta diabetologica

authors： Unlüçerçi YM,Bekpinar S,Seferoglu G

更新日期：2000-01-01 00:00:00

abstract：AIMS:To assess the metabolic health of obese and non-obese women at high GDM risk 5 years postpartum. METHODS:This is a secondary analysis of the 5-year follow-up of the RADIEL GDM prevention study including 333 women at high GDM risk (BMI ≥ 30 kg/m2 and/or previous GDM). Five years postpartum metabolic health was ass...

journal_title：Acta diabetologica

authors： Huvinen E,Eriksson JG,Koivusalo SB,Grotenfelt N,Tiitinen A,Stach-Lempinen B,Rönö K

更新日期：2018-05-01 00:00:00

abstract：:We investigated whether food supplementation within the first year life or age at introduction of gluten-containing foods influenced the risk of developing islet autoimmunity and type 1 diabetes. A total of 2,291 children with a family history of type 1 diabetes were prospectively followed from birth for 28,983 patien...

journal_title：Acta diabetologica

authors： Chmiel R,Beyerlein A,Knopff A,Hummel S,Ziegler AG,Winkler C

更新日期：2015-06-01 00:00:00

abstract：:Bacterial endotoxins have been associated with chronic inflammation and the development and progression of diabetic nephropathy. We hypothesized that subjects with high serum lipopolysaccharide activity also carry remains of bacterial DNA in their system. Serum-derived bacterial DNA clones were isolated and identified...

journal_title：Acta diabetologica

authors： Peräneva L,Fogarty CL,Pussinen PJ,Forsblom C,Groop PH,Lehto M

更新日期：2013-06-01 00:00:00

abstract：AIMS:The aims of this study were: to develop new equations for predicting resting energy expenditure (REE) in obese Italian subjects according to body composition parameters; to compare them with predicted values estimated by other REE prediction equations; and to cross-validate our equations using a validation set coh...

journal_title：Acta diabetologica

authors： De Lorenzo A,Di Renzo L,Morini P,de Miranda RC,Romano L,Colica C

更新日期：2018-01-01 00:00:00

abstract：:Hyperglycaemia caused by stress and inflammation is common during critical illness. We hypothesised that a latent glucose metabolism disturbance contributes to development of hyperglycaemia and that those patients have increased risk for diabetes. We included patients with sepsis, acute coronary syndrome and acute hea...

journal_title：Acta diabetologica

authors： Gornik I,Vujaklija A,Lukić E,Madžarac G,Gašparović V

更新日期：2010-12-01 00:00:00

abstract：AIMS:Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase in SIRT-1 expression affects histone 3 acetylation at the 56 lysine residue (H3K56ac) in T2DM patients randomly selected to receive ei...

journal_title：Acta diabetologica

authors： Bo S,Togliatto G,Gambino R,Ponzo V,Lombardo G,Rosato R,Cassader M,Brizzi MF

更新日期：2018-04-01 00:00:00

abstract：:Microalbuminuria in diabetic patients is associated with an increased cardiovascular risk which is not completely explained by an excess of conventional cardiovascular risk factors. A depression of physiologic inhibitors of blood coagulation could contribute to a thrombophilic state and to cardiovascular complications...

journal_title：Acta diabetologica

authors： Veglio M,Gruden G,Mormile A,Girotto M,Rossetto P,D'Este P,Cavallo-Perin P

更新日期：1995-06-01 00:00:00

abstract：:The aim of this research was the evaluation of polymorphonuclear leukocyte (PMN) membrane fluidity in subjects with insulin resistance. Insulin sensitivity, in fact, may be influenced by plasma membrane fluidity. We enrolled 19 subjects with insulin resistance previously demonstrated during an euglycemic hyperinsuline...

journal_title：Acta diabetologica

authors： Caimi G,Sinagra D,Canino B,Scarpitta AM,Montana M,Bonaventura V,Lo Presti R

更新日期：2000-03-01 00:00:00

abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...

journal_title：Acta diabetologica

authors： Shalitin S,Ben-Ari T,Yackobovitch-Gavan M,Tenenbaum A,Lebenthal Y,de Vries L,Phillip M

更新日期：2014-04-01 00:00:00

abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

journal_title：Acta diabetologica

authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

更新日期：2020-04-01 00:00:00

abstract：AIMS:Our aims were to investigate in several large samples, with a wide range of adiposity, whether: (1) the effect of BMI on insulin sensitivity is different between sexes; (2) also waist circumference plays a sex-specific role on insulin sensitivity; and (3) serum adiponectin and resistin are mediators of such sex-di...

journal_title：Acta diabetologica

authors： Marucci A,Menzaghi C,Copetti M,Vinciguerra F,Baratta R,Salvemini L,Morini E,Frittitta L,Di Paola R,Trischitta V

更新日期：2015-10-01 00:00:00

abstract：:Post-prandial hyperglycemia is considered a relevant therapeutic target in type 2 diabetic patients, and it could represent per se an independent risk factor for diabetic complications. Aim of the present systematic review is to collect and summarize evidence from observational studies on the relationship between post...

journal_title：Acta diabetologica

authors： Mannucci E,Monami M,Lamanna C,Adalsteinsson JE

更新日期：2012-08-01 00:00:00