The effect of aminoguanidine on urinary heparan sulphate levels in experimental diabetes.

abstract：AIMS:Observational studies indicated that resting heart rate (RHR) was associated with diabetes mellitus (DM) risk; however, it remains unclear whether the association between RHR and DM is causal. We aimed to examine whether there was causal association of RHR with DM risk. METHODS:A prospective study including 16,20...

journal_title：Acta diabetologica

authors： Long T,Wang J,Han X,Wang F,Hu H,Yu C,Yuan J,Yao P,Wei S,Wang Y,Liang Y,Miao X,Zhang X,Guo H,Zheng D,Tang Y,Yang H,Huang S,He M

更新日期：2019-09-01 00:00:00

abstract：AIM:Infection of a diabetic foot ulcer (DFU) is common. More than the half of DFUs become infected and 15-20% of them necessitate amputation in course of treatment. Diabetic foot infection (DFI) is therefore the major cause for non-traumatic lower limb amputation in Germany. Prompt and effective treatment of DFI is man...

journal_title：Acta diabetologica

authors： Dörr S,Freier F,Schlecht M,Lobmann R

更新日期：2020-09-17 00:00:00

abstract：AIMS:Our aims were to investigate in several large samples, with a wide range of adiposity, whether: (1) the effect of BMI on insulin sensitivity is different between sexes; (2) also waist circumference plays a sex-specific role on insulin sensitivity; and (3) serum adiponectin and resistin are mediators of such sex-di...

journal_title：Acta diabetologica

authors： Marucci A,Menzaghi C,Copetti M,Vinciguerra F,Baratta R,Salvemini L,Morini E,Frittitta L,Di Paola R,Trischitta V

更新日期：2015-10-01 00:00:00

abstract：AIMS:Radiolabeled Exendin-4 has been proposed as suitable imaging marker for pancreatic beta cell mass quantification mediated by Glucagon-like peptide-1 receptor (GLP-1R). However, noticeable species variations in basal pancreatic uptake as well as uptake reduction degree due to selective beta cell ablation were obser...

journal_title：Acta diabetologica

authors： Eriksson O,Rosenström U,Selvaraju RK,Eriksson B,Velikyan I

更新日期：2017-11-01 00:00:00

abstract：AIMS:To define the possible effect of diabetic conditions on megakaryocytes, the long-know precursors of platelets and lately characterized modulator of hematopoietic stem quiescence-activation transition. METHODS:Megakaryoblastic MEG-01 cell culture and TPO/SCF/IL-3-induced differentiation of human umbilical blood mo...

journal_title：Acta diabetologica

authors： Wang B,Yu J,Wang T,Shen Y,Lin D,Xu X,Wang Y

更新日期：2018-05-01 00:00:00

abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...

journal_title：Acta diabetologica

authors： Shalitin S,Ben-Ari T,Yackobovitch-Gavan M,Tenenbaum A,Lebenthal Y,de Vries L,Phillip M

更新日期：2014-04-01 00:00:00

abstract：AIMS:Glucagon is used to resolve severe hypoglycemia in unconscious patients with diabetes, requiring third-party assistance. A few studies have shown that intranasal (IN) glucagon causes resolution of hypoglycemia in insulin-treated patients with type 1 (T1DM) diabetes. This systematic review and meta-analysis updates...

journal_title：Acta diabetologica

authors： Pontiroli AE,Tagliabue E

更新日期：2020-06-01 00:00:00

abstract：:Diabetic neuropathy is a significant complication of chronic diabetes. We wished to discover whether we were successfully identifying patients who had developed neuropathic problems. Specifically, Diabetologists are traditionally poor at asking about erectile dysfunction (ED) and patients themselves are not always for...

journal_title：Acta diabetologica

authors： Grant PS,Lipscomb D

更新日期：2009-12-01 00:00:00

abstract：AIMS:The aims of this study were: to develop new equations for predicting resting energy expenditure (REE) in obese Italian subjects according to body composition parameters; to compare them with predicted values estimated by other REE prediction equations; and to cross-validate our equations using a validation set coh...

journal_title：Acta diabetologica

authors： De Lorenzo A,Di Renzo L,Morini P,de Miranda RC,Romano L,Colica C

更新日期：2018-01-01 00:00:00

abstract：:Consistent with the postulated role of oxidative stress in the etiology of late diabetic complications, pharmacological interventions based on biological antioxidants have been suggested. The aim of the present study was to investigate the effect of dietary supplementation with the pyridoindole antioxidant stobadine o...

journal_title：Acta diabetologica

authors： Stefek M,Sotnikova R,Okruhlicova L,Volkovova K,Kucharska J,Gajdosik A,Gajdosikova A,Mihalova D,Hozova R,Tribulova N,Gvozdjakova A

更新日期：2000-01-01 00:00:00

abstract：AIMS:There is clinical evidence that fenofibrate, a PPARα agonist, arrests the progression of diabetic macular edema (DME). However, the underlying mechanisms of this beneficial effect remain to be elucidated. We previously reported that fenofibric acid (FA), the active metabolite of fenofibrate, prevents the disorgani...

journal_title：Acta diabetologica

authors： Garcia-Ramírez M,Hernández C,Palomer X,Vázquez-Carrera M,Simó R

更新日期：2016-02-01 00:00:00

abstract：:The objective of this study was to describe spatial and space-time patterns of type 1 diabetes in children less than 15 years old, diagnosed between 2000 and 2005 with residence in the Metropolitan Region of Chile. Knox and Mantel tests were used to detect space-time interaction between cases. An ecological Bayesian m...

journal_title：Acta diabetologica

authors： Torres-Avilés F,Carrasco E,Icaza G,Pérez-Bravo F

更新日期：2010-09-01 00:00:00

abstract：:Although reactive oxygen species (ROS) contribute to glucose intolerance induced by the renin-angiotensin system (RAS) is well documented, the role of the newly discovered pathway of RAS, angiotensin (Ang)-(1-7)/Mas axis, in this process remains unknown. Here, we examined the effect of Ang-(1-7) on oxidative stress an...

journal_title：Acta diabetologica

authors： Liu C,Lv XH,Li HX,Cao X,Zhang F,Wang L,Yu M,Yang JK

更新日期：2012-08-01 00:00:00

abstract：:Genetic markers may be used to improve the prediction of insulin-dependent diabetes mellitus (type 1) in individuals with islet autoantibodies. In order to develop a risk assessment strategy for the Lombardy region of northern Italy based on genetic and immunological markers, we analyzed HLA DQA1 and DQB1 alleles in 6...

journal_title：Acta diabetologica

authors： Lampasona V,Ferrari M,Bonifacio E,Pastore MR,Carrera P,Sergi A,Genovese S,Trucco M,Dorman J,Bosi E

更新日期：1995-10-01 00:00:00

abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

journal_title：Acta diabetologica

authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

更新日期：2020-04-01 00:00:00

abstract：:Selective loss of capillary pericytes occurs early and specifically in diabetic retinopathy. We have investigated whether blood derivatives from patients with long-term type 1 (insulin-dependent) diabetes and no retinopathy differ from those with retinopathy and/or non-diabetic controls in their ability to stimulate D...

journal_title：Acta diabetologica

authors： Williams FM,Dosso AA,Kohner EM,Porta M

更新日期：1993-01-01 00:00:00

abstract：AIMS:To evaluate feasibility and effectiveness on short-term blood glucose control of using glycaemic load counting (GLC) versus carbohydrate counting (CC) for prandial insulin dosing in patients with type 1 diabetes (T1D). METHODS:Nine T1D patients on insulin pump, aged 26-58 years, HbA1c 7.7 ± 0.8 % (61 ± 8.7 mmol/m...

journal_title：Acta diabetologica

authors： Bozzetto L,Giorgini M,Alderisio A,Costagliola L,Giacco A,Riccardi G,Rivellese AA,Annuzzi G

更新日期：2015-10-01 00:00:00

abstract：AIMS:The relationship between bisphenol A (BPA) and diabetes remains controversial. This study aims to investigate whether serum BPA level could predict the 5-year incidence of type 2 diabetes (T2D). METHODS:A nested case-control study was performed among Chinese who participated in the environment, inflammation and m...

journal_title：Acta diabetologica

authors： Shu X,Tang S,Peng C,Gao R,Yang S,Luo T,Cheng Q,Wang Y,Wang Z,Zhen Q,Hu J,Li Q

更新日期：2018-04-01 00:00:00

abstract：AIMS:To investigate the associations of vitamin B12 (cobalamin and holotranscobalamin) status with depression, cognition and neuropathy in patients with type 2 diabetes using metformin. METHODS:In an observational study, among 550 type 2 diabetes patients using metformin, cobalamin and holotranscobalamin (holoTCII) le...

journal_title：Acta diabetologica

authors： Biemans E,Hart HE,Rutten GE,Cuellar Renteria VG,Kooijman-Buiting AM,Beulens JW

更新日期：2015-04-01 00:00:00

abstract：:To study the immune response to glutamic acid decarboxylase (GAD) in insulin-dependent diabetes mellitus, monoclonal GAD antibodies after fusion of splenocytes from a nondiabetes-susceptible BALB/c mouse immunized with human recombinant GAD65 were generated. Of the 44 monoclonals, 35 are specific for the GAD65 isoform...

journal_title：Acta diabetologica

authors： Ziegler B,Schlosser M,Lühder F,Strebelow M,Augstein P,Northemann W,Powers AC,Ziegler M

更新日期：1996-09-01 00:00:00

abstract：:Despite advances in technology, the frequent self-measurement of blood glucose (SMBG) remains fundamental to the management of 1 diabetes mellitus (T1DM). Once measured, SMBG results are routinely reported back to health professionals and other interested parties, either verbally, via a logbook, or electronically down...

journal_title：Acta diabetologica

authors： Blackwell M,Wheeler BJ

更新日期：2017-01-01 00:00:00

abstract：:The assessment of body composition and energy requirements is important for the nutrition of healthy and pathological states such as gastrointestinal disorders, which are known to be associated with abnormalities in body composition among persons with malnutrition and malabsorption. Careful monitoring of body composit...

journal_title：Acta diabetologica

authors： De Lorenzo A,Maiolo C,Mohamed EI,Casini A

更新日期：2003-10-01 00:00:00

abstract：AIMS:To assess the time-dependent effect of sleep quality on diabetes and coronary artery disease (CAD) incidence among young adults. METHODS:Incident rates of diabetes and CAD during a mean follow-up of 6.4 ± 4.1 years were assessed among 26,023 men (mean age 30.9 ± 5.6 years) of the Metabolic Lifestyle and Nutrition...

journal_title：Acta diabetologica

authors： Twig G,Shina A,Afek A,Derazne E,Tzur D,Cukierman-Yaffe T,Shechter-Amir D,Gerstein HC,Tirosh A

更新日期：2016-04-01 00:00:00

abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...

journal_title：Acta diabetologica

authors： Pozzuoli GM,Laudato M,Barone M,Crisci F,Pozzuoli B

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to evaluate the prevalence of thyroid autoantibodies and clinical significance of thyroid autoimmunity in children with the diagnosis of diabetes mellitus type 1. The study group comprised 222 children all with newly diagnosed diabetes mellitus type 1 (122 boys) with a mean age 9.92 +/- 4.5 y...

journal_title：Acta diabetologica

authors： Machnica L,Osior A,Jarosz-Chobot P,Deja G,Polanska J,Otto-Buczkowska E

更新日期：2008-03-01 00:00:00

abstract：:Administration of exogenous insulin for the treatment of diabetes is often accompanied by the development of insulin antibodies (IA). These antibodies may affect the patient's requirement for insulin by acting as an insulin binding reservoir. The improvement of insulin purification in the 1970s and the development of ...

journal_title：Acta diabetologica

authors： Oak S,Phan TH,Gilliam LK,Hirsch IB,Hampe CS

更新日期：2010-06-01 00:00:00

abstract：:The objective of this study is to explore the mechanism of oxidative stress induced by intermittent high glucose in porcine iliac endothelial cells (PIECs). The PIECs were exposed to intermittent or constant high glucose for 3 or 6 days, and the mean fluorescent intensity (MFI) was measured via intracellular reactive ...

journal_title：Acta diabetologica

authors： Ge QM,Dong Y,Zhang HM,Su Q

更新日期：2010-12-01 00:00:00

abstract：:The aim of the present work was to investigate the impact of gender on resting cerebral blood flow velocity and cerebrovascular reserve capacity among diabetic patients. Middle cerebral artery mean blood flow velocity (MCAV) was measured in 72 patients suffering from type 1 diabetes mellitus at rest and 5, 10, 15 and ...

journal_title：Acta diabetologica

authors： Fülesdi B,Limburg M,Oláh L,Bereczki D,Csiba L,Kollár J

更新日期：2001-01-01 00:00:00

abstract：:Cyclosporin and methotrexate administration induces remission of type 1 diabetes mellitus. Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). Its usefulness was limited by its toxicity. Since methotrexate (mtx) and cyclo synergistically inhibit ...

journal_title：Acta diabetologica

authors： Sobel DO,Henzke A,Abbassi V

更新日期：2010-09-01 00:00:00

abstract：AIMS:The anti-inflammatory effects of the polyphenol resveratrol in patients with type 2 diabetes mellitus (T2DM) are controversial. Its role on pentraxin 3 (PTX3) concentrations, a human acute phase protein, has never been evaluated. Our aim was to determine whether a two-dosage resveratrol supplementation (500 and 40...

journal_title：Acta diabetologica

authors： Bo S,Ponzo V,Evangelista A,Ciccone G,Goitre I,Saba F,Procopio M,Cassader M,Gambino R

更新日期：2017-05-01 00:00:00