Effects of intermittent high glucose on oxidative stress in endothelial cells.

abstract：:A cross-sectional descriptive study was done on patients recently entered into the National Diabetes Registry in Eritrea where the prevalence was estimated to be 2.2% based on patient information in 2004. Of the 627 patients with diabetes, two thirds were type 2. Although type 1 had poorer control (42.9%) than type 2 ...

journal_title：Acta diabetologica

authors： Seyum B,Mebrahtu G,Usman A,Mufunda J,Tewolde B,Haile S,Kosia A,Negassi E

更新日期：2010-03-01 00:00:00

abstract：:We investigated the effect of sub-chronic soybean oil (SO) treatment on the insulin secretion and fatty acid composition of islets of Langerhans obtained from Goto-Kakizaki (GK), a model of type 2 diabetes, and normal Wistar rats. We observed that soybean-treated Wistar rats present insulin resistance and defective is...

journal_title：Acta diabetologica

authors： Nunes E,Peixoto F,Louro T,Sena CM,Santos MS,Matafome P,Moreira PI,Seiça R

更新日期：2007-09-01 00:00:00

abstract：AIMS:Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase in SIRT-1 expression affects histone 3 acetylation at the 56 lysine residue (H3K56ac) in T2DM patients randomly selected to receive ei...

journal_title：Acta diabetologica

authors： Bo S,Togliatto G,Gambino R,Ponzo V,Lombardo G,Rosato R,Cassader M,Brizzi MF

更新日期：2018-04-01 00:00:00

abstract：:The aim of the present work was to investigate the impact of gender on resting cerebral blood flow velocity and cerebrovascular reserve capacity among diabetic patients. Middle cerebral artery mean blood flow velocity (MCAV) was measured in 72 patients suffering from type 1 diabetes mellitus at rest and 5, 10, 15 and ...

journal_title：Acta diabetologica

authors： Fülesdi B,Limburg M,Oláh L,Bereczki D,Csiba L,Kollár J

更新日期：2001-01-01 00:00:00

abstract：AIMS:Type 2 diabetes (T2D) is a metabolic disorder requiring intensive self-care to maintain optimal glycemic control. Sleep disturbance is common in T2D patients and likely impairs glycemic control. Our aim was to examine the relationship between sleep disturbance and self-care in adults with T2D. METHODS:This study ...

journal_title：Acta diabetologica

authors： Zhu B,Quinn L,Kapella MC,Bronas UG,Collins EG,Ruggiero L,Park CG,Fritschi C

更新日期：2018-09-01 00:00:00

abstract：:The original report on the microencapsulation of islets of Langerhans used sodium alginate and poly-L-lysine (PLL) to form the capsules. Although several alternative materials have subsequently been used with vary-mg degrees of success, it is those studies using islets encapsulated in alginate-PLL-alginate which are r...

journal_title：Acta diabetologica

authors： Clayton HA,James RF,London NJ

更新日期：1993-01-01 00:00:00

abstract：AIMS:Diabetic ketoacidosis (DKA) at diabetes diagnosis is a dangerous yet potentially preventable condition. Young age, low socioeconomic status, and low parental education have been found to be associated with increased risk of DKA. We aimed to evaluate the impact of religious affiliation on presentation with DKA at t...

journal_title：Acta diabetologica

authors： Gruber N,Reichman B,Lerner-Geva L,Pinhas-Hamiel O

更新日期：2015-04-01 00:00:00

abstract：:Diabetes mellitus, the most common serious metabolic disorder, is characterized by functional and structural changes in the peripheral and central nervous systems. Glial cells provide structural and metabolic support for retinal neurons. During diabetes, one of the early pathogenic events is retinal glial reactivity. ...

journal_title：Acta diabetologica

authors： Baydas G,Tuzcu M,Yasar A,Baydas B

更新日期：2004-09-01 00:00:00

abstract：AIMS:To assess the metabolic health of obese and non-obese women at high GDM risk 5 years postpartum. METHODS:This is a secondary analysis of the 5-year follow-up of the RADIEL GDM prevention study including 333 women at high GDM risk (BMI ≥ 30 kg/m2 and/or previous GDM). Five years postpartum metabolic health was ass...

journal_title：Acta diabetologica

authors： Huvinen E,Eriksson JG,Koivusalo SB,Grotenfelt N,Tiitinen A,Stach-Lempinen B,Rönö K

更新日期：2018-05-01 00:00:00

abstract：:The effect of sucrose in the diet of children and adolescents with type I diabetes on long-term metabolic control was studied. For a mean observation period of 83 (range 42-127) days, a diet containing 5% of total calories as refined sugar was recommended to 11 children (group A, mean age 15.0, SD 5.4 years), while an...

journal_title：Acta diabetologica

authors： Schwingshandl J,Rippel S,Unterluggauer M,Borkenstein M

更新日期：1994-12-01 00:00:00

abstract：:For many diabetic patients, years of blood glucose self-monitoring (SM) with readings taken several times daily is an inevitable aspect of insulin therapy. We investigated whether SM from abdominal skin might be an alternative to the established fingertip method. A total of 63 diabetic patients and 16 nondiabetic volu...

journal_title：Acta diabetologica

authors： Holstein A,Thiessen E,Kaufmann N,Plaschke A,Egberts EH

更新日期：2002-06-01 00:00:00

abstract：AIM:It is unclear whether any breastfeeding or a certain duration of breastfeeding is protective against the development of diabetes in adult offspring. METHODS:We followed a sub-sample of 3,595 offspring born in the Mater Hospital in Brisbane, Australia between 1981 and 1983 and for whom we had doctor diagnosed self-...

journal_title：Acta diabetologica

authors： Al Mamun A,O'Callaghan MJ,Williams GM,Najman JM,Callaway L,McIntyre HD

更新日期：2015-10-01 00:00:00

abstract：:Comparing macrophage-derived cytokine and nitric oxide (NO) profiles in type I and type II diabetes mellitus (DM); and determining whether thymoquinone (TQ) has any modulatory effect were the main objectives of the present study. Peritoneal macrophages have been collected from Otsuka Long-Evans Tokushima Fatty (OLETF)...

journal_title：Acta diabetologica

authors： El-Mahmoudy A,Shimizu Y,Shiina T,Matsuyama H,Nikami H,Takewaki T

更新日期：2005-03-01 00:00:00

abstract：:The aim of this study was to evaluate lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes, and then to establish whether moderate doses of nonenzymatic antioxidant vitamin E play a role in the antioxidant defence system in diabetic pregnant rats and their offspring. The study group con...

journal_title：Acta diabetologica

authors： Kinalski M,Sledziewski A,Telejko B,Zarzycki W,Kinalska I

更新日期：2000-01-01 00:00:00

abstract：:We have measured protein phosphatase (PP) activity in crude homogenates as well as in the total 105.000 x g supernatant and precipitate fractions from normal rat pancreatic islets. On the basis of the inhibition produced by either 1 nM or 1 microM okadaic acid, both PP1 and PP2A activity were present in crude islet ho...

journal_title：Acta diabetologica

authors： Gagliardino JJ,Rossi PF,García ME

更新日期：1997-03-01 00:00:00

abstract：AIMS:This subanalysis of a cross-sectional, nationwide study was undertaken to assess the relationship between healthy lifestyle behaviors and multiple cardiovascular risk factors among people with type 2 diabetes mellitus (T2DM). METHODS:Data collected from 25,454 participants, including demographics, lifestyle behav...

journal_title：Acta diabetologica

authors： Huang Y,Li J,Zhu X,Sun J,Ji L,Hu D,Pan C,Tan W,Jiang S,Tao X,CCMR-3B STUDY Investigators.

更新日期：2017-06-01 00:00:00

abstract：AIMS:In patients with type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and liver fibrosis is frequent and presumably associated with increased cardiovascular disease risk and mortality. The objective was to investigate risk factors associated with hepatic fibrosis in patients with type 2 diabetes and NAFLD to...

journal_title：Acta diabetologica

authors： Mansour A,Mohajeri-Tehrani MR,Samadi M,Gerami H,Qorbani M,Bellissimo N,Poustchi H,Hekmatdoost A

更新日期：2019-11-01 00:00:00

abstract：:The aim of this research was the evaluation of polymorphonuclear leukocyte (PMN) membrane fluidity in subjects with insulin resistance. Insulin sensitivity, in fact, may be influenced by plasma membrane fluidity. We enrolled 19 subjects with insulin resistance previously demonstrated during an euglycemic hyperinsuline...

journal_title：Acta diabetologica

authors： Caimi G,Sinagra D,Canino B,Scarpitta AM,Montana M,Bonaventura V,Lo Presti R

更新日期：2000-03-01 00:00:00

abstract：:In late twentieth century, Ruderman and Reaven showed that insulin resistance might be fundamental to metabolic syndrome (MetS) which means a constellation of obesity-related metabolic derangements predisposing to type 2 diabetes and cardiovascular disease. In 2001, user-friendly National Cholesterol Education Program...

journal_title：Acta diabetologica

authors： Oda E

更新日期：2012-04-01 00:00:00

abstract：AIMS:Our aims were to investigate in several large samples, with a wide range of adiposity, whether: (1) the effect of BMI on insulin sensitivity is different between sexes; (2) also waist circumference plays a sex-specific role on insulin sensitivity; and (3) serum adiponectin and resistin are mediators of such sex-di...

journal_title：Acta diabetologica

authors： Marucci A,Menzaghi C,Copetti M,Vinciguerra F,Baratta R,Salvemini L,Morini E,Frittitta L,Di Paola R,Trischitta V

更新日期：2015-10-01 00:00:00

abstract：AIMS:Fat accumulation in the liver and in the muscle results in hepatic and muscle insulin resistance and has been associated with increased cardiovascular risk. It is unclear whether the individual role of hepatic and muscle insulin resistance in the onset of dyslipidaemia is observed in nonalcoholic fatty liver disea...

journal_title：Acta diabetologica

authors： Privitera G,Spadaro L,Alagona C,Calanna S,Piro S,Rabuazzo AM,Purrello F

更新日期：2016-06-01 00:00:00

abstract：AIMS:To study the incidence of and the factors associated with renal dialysis and transplantation in type 1 (T1DM) and type 2 diabetes (T2DM). METHODS:Data on individuals who had received dialysis treatment or renal transplant between 1 January 2004 and 31 December 2013 were extracted from the regional administrative ...

journal_title：Acta diabetologica

authors： Giorda CB,Carnà P,Salomone M,Picariello R,Costa G,Tartaglino B,Gnavi R

更新日期：2018-07-01 00:00:00

abstract：:Genetic markers may be used to improve the prediction of insulin-dependent diabetes mellitus (type 1) in individuals with islet autoantibodies. In order to develop a risk assessment strategy for the Lombardy region of northern Italy based on genetic and immunological markers, we analyzed HLA DQA1 and DQB1 alleles in 6...

journal_title：Acta diabetologica

authors： Lampasona V,Ferrari M,Bonifacio E,Pastore MR,Carrera P,Sergi A,Genovese S,Trucco M,Dorman J,Bosi E

更新日期：1995-10-01 00:00:00

abstract：:This 64-week prospective cohort trial evaluated the effects of 20-mg oestradiol implants, replaced every 4 months, in healthy postmenopausal women aged 45-65 years. Of 20 implant and 14 control subjects who remained in the trial at 32 weeks, 13 implant and seven controls continued to 64 weeks, with no baseline differe...

journal_title：Acta diabetologica

authors： Hansen RD,Raja C,Baber RJ,Lieberman D,Allen BJ

更新日期：2003-10-01 00:00:00

abstract：:The objective is to assess the effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar rats, 8-week-old, were categorized into four groups, which were the control (n = 9), diabetes (n = 9), infliximab-treated diabetes (n = 10), and FR167653-treated diabetes (n = 9) groups...

journal_title：Acta diabetologica

authors： Moriwaki Y,Inokuchi T,Yamamoto A,Ka T,Tsutsumi Z,Takahashi S,Yamamoto T

更新日期：2007-12-01 00:00:00

abstract：:Aim of this study was to formulate an index for glucose effectiveness (Sg), SgIo, based on 3-point (0, 30 and 120 min) 75 g oral glucose tolerance test (OGTT). The equation for SgI(O) was developed in the Chikuma cohort (n = 502). Firstly, post-loading plasma glucose without insulin action and Sg (PPG-without insulin ...

journal_title：Acta diabetologica

authors： Nagasaka S,Kusaka I,Yamashita K,Funase Y,Yamauchi K,Katakura M,Ishibashi S,Aizawa T

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Emerging adulthood is a challenging period for diabetes management. Our aim was to determine whether a dedicated transition clinic for emerging adults with type 1 diabetes can improve glycemic control and visit attendance. METHODS:An observational study of 53 emerging adults (30 males) treated during 2010-2...

journal_title：Acta diabetologica

authors： Levy-Shraga Y,Elisha N,Ben-Ami M,Boyko V,Lerner-Geva L,Ziv T,Konvalina N,Cohen O,Pinhas-Hamiel O

更新日期：2016-02-01 00:00:00

abstract：AIMS:The present study aims to investigate the association between serum ferritin and diabetes, diabetes control, and insulin resistance (IR) and examine whether gender is a modifier for these associations in a community-based sample. METHODS:A cross-sectional survey of 8,235 participants was conducted in 2009. Serum ...

journal_title：Acta diabetologica

authors： Zhan Y,Tang Z,Yu J

更新日期：2014-12-01 00:00:00

abstract：:Diabetes mellitus and hyperglycaemia are both independent risk factors (RF) for cardiovascular (CV) events and increased general and CV mortality. Type 2 diabetes, which is often associated with obesity, hypertension and dyslipidaemia, is accompanied by an up to fourfold increase in the incidence of acute coronary hea...

journal_title：Acta diabetologica

authors： Beltramello G,Manicardi V,Mazzuoli F,Rivellese A,Associazione Medici Diabetologi (AMD), Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO), Federazione delle Associazioni dei Dirigenti Ospedalieri Internisti (FADOI) and Societa` Italia

更新日期：2013-12-01 00:00:00

abstract：:We determined in non-diabetic persons the risk of fasting and non-fasting glucose levels for pre-diabetes, diabetes, and coronary heart disease (CHD), including the roles of serum C-reactive protein (CRP) and HDL cholesterol, and delineated risk profiles of the pre-diabetic states. Over 7¼ years, 2,619 middle-aged Tur...

journal_title：Acta diabetologica

authors： Onat A,Can G,Çiçek G,Ayhan E,Doğan Y,Kaya H

更新日期：2013-08-01 00:00:00