Ten-year comparative analysis of incidence, prognosis, and associated factors for dialysis and renal transplantation in type 1 and type 2 diabetes versus non-diabetes.

abstract：:Postreceptor insulin resistance was studied in liver, muscle and adipose tissue from NMRI mice of both sexes made diabetic by long-term fat-feeding. Intravenous glucose tolerance tests showed a combination of impaired glucose tolerance and increased plasma insulin concentrations consistent with insulin resistance and ...

journal_title：Acta diabetologica

authors： Hedeskov CJ,Capito K,Islin H,Hansen SE,Thams P

更新日期：1992-01-01 00:00:00

abstract：:Selective loss of capillary pericytes occurs early and specifically in diabetic retinopathy. We have investigated whether blood derivatives from patients with long-term type 1 (insulin-dependent) diabetes and no retinopathy differ from those with retinopathy and/or non-diabetic controls in their ability to stimulate D...

journal_title：Acta diabetologica

authors： Williams FM,Dosso AA,Kohner EM,Porta M

更新日期：1993-01-01 00:00:00

abstract：AIMS:The aim of the current study was to investigate the association of type 2 diabetes (T2D) and insulin treatment with changes in muscle mass, muscle strength, and physical performance in older adults. METHODS:In 731 participants of the population-based KORA-Age study aged 74.6 ± 6.2 years (T2D: n = 118; insulin tre...

journal_title：Acta diabetologica

authors： Ferrari U,Then C,Rottenkolber M,Selte C,Seissler J,Conzade R,Linkohr B,Peters A,Drey M,Thorand B

更新日期：2020-09-01 00:00:00

abstract：:Cardiovascular diseases represent, today, the principal cause of mortality in the general population, especially in subjects with type 2 diabetes mellitus. In these patients the risk of death from cardiovascular diseases is equal to that of non-diabetic subjects with a previous episode of myocardial infarction. Many f...

journal_title：Acta diabetologica

authors： Palumbo F,Bianchi C,Miccoli R,Del Prato S

更新日期：2003-12-01 00:00:00

abstract：:We analysed the risk factors associated with diabetic complications in the cohort of patients assisted by a type 2 diabetes mellitus (T2DM) shared-care program. We analysed registry data from 16,136 T2DM patients. Of them, 4,781 had microangiopathy, 3,469 CV events. They were 70.5 ± 17.1 years old, 50% were male, dise...

journal_title：Acta diabetologica

authors： Ciardullo AV,Daghio MM,Bevini M,Feltri G,Novi D,Fattori G,Borsari S,Donato CD

更新日期：2010-12-01 00:00:00

abstract：AIMS:To evaluate the methodological quality of systematic reviews (SRs), and summarize evidence of important outcomes from dipeptidyl peptidase-4 inhibitors (DPP4-I) in treating type 2 diabetes mellitus (T2DM). METHODS:We included SRs of DPP4-I for the treatment of T2DM until January, 2018 by searching the Cochrane Li...

journal_title：Acta diabetologica

authors： Ling J,Ge L,Zhang DH,Wang YF,Xie ZL,Tian JH,Xiao XH,Yang KH

更新日期：2019-01-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has an important role in the endocrine pancreas. Multiple researches have shown that even in the insulin resistance phase, there are many abnormalities in islets morphology and function. This study aimed at investigating the effects of RAS blockade on the islets function in rats with...

journal_title：Acta diabetologica

authors： Yuan L,Li X,Li J,Li HL,Cheng SS

更新日期：2013-08-01 00:00:00

abstract：:Pancreatic volume and fat content might be associated with β-cell function or insulin resistance (IR). We investigated the difference in pancreatic volume and fat content between age- and body mass index (BMI)-matched normal subjects and patients with having different durations of type 2 diabetes (T2D). We compared pa...

journal_title：Acta diabetologica

authors： Lim S,Bae JH,Chun EJ,Kim H,Kim SY,Kim KM,Choi SH,Park KS,Florez JC,Jang HC

更新日期：2014-10-01 00:00:00

abstract：:Insulin secretion is stimulated better by oral than by intravenous glucose (incretin effect). The contribution of the autonomic nervous system to the incretin effect after oral glucose in humans is unclear. We therefore examined nine type 1 diabetic (insulin-dependent) patients with end-stage nephropathy, studied afte...

journal_title：Acta diabetologica

authors： Nauck MA,Büsing M,Orskov C,Siegel EG,Talartschik J,Baartz A,Baartz T,Hopt UT,Becker HD,Creutzfeldt W

更新日期：1993-01-01 00:00:00

abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...

journal_title：Acta diabetologica

authors： Pozzuoli GM,Laudato M,Barone M,Crisci F,Pozzuoli B

更新日期：2018-01-01 00:00:00

abstract：AIMS:Increasing evidence suggests a potential role of circulating miRNAs as clinical biomarkers, and loss of miRNA-126 has been proposed as a predictor of type 2 diabetes onset. However, a systematic analysis of circulating miRNAs in type 1 diabetic patients with micro-/macrovascular complications has not yet been perf...

journal_title：Acta diabetologica

authors： Barutta F,Bruno G,Matullo G,Chaturvedi N,Grimaldi S,Schalkwijk C,Stehouwer CD,Fuller JH,Gruden G

更新日期：2017-02-01 00:00:00

abstract：:In the perfused pancreas of adult rats that were injected with streptozotocin (STZ) during the neonatal period, the release of insulin caused by glucose is more severely affected than that evoked by other secretagogues. We have now examined whether a comparable situation prevails in vivo. In anesthetised rats, the 0-1...

journal_title：Acta diabetologica

authors： Vicent D,Villanueva-Peñacarrillo ML,Valverde I,Malaisse WJ

更新日期：1994-09-01 00:00:00

abstract：AIMS:Observational studies indicated that resting heart rate (RHR) was associated with diabetes mellitus (DM) risk; however, it remains unclear whether the association between RHR and DM is causal. We aimed to examine whether there was causal association of RHR with DM risk. METHODS:A prospective study including 16,20...

journal_title：Acta diabetologica

authors： Long T,Wang J,Han X,Wang F,Hu H,Yu C,Yuan J,Yao P,Wei S,Wang Y,Liang Y,Miao X,Zhang X,Guo H,Zheng D,Tang Y,Yang H,Huang S,He M

更新日期：2019-09-01 00:00:00

abstract：:Cyclosporin and methotrexate administration induces remission of type 1 diabetes mellitus. Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). Its usefulness was limited by its toxicity. Since methotrexate (mtx) and cyclo synergistically inhibit ...

journal_title：Acta diabetologica

authors： Sobel DO,Henzke A,Abbassi V

更新日期：2010-09-01 00:00:00

abstract：:This study examined whether or not changes in plasma concentrations of motilin and other gastrointestinal hormones known to affect gastric motility are associated with the accelerated gastric emptying seen during hypoglycaemia. While studying gastric emptying by scintigraphy in eight healthy subjects, the plasma conce...

journal_title：Acta diabetologica

authors： Schvarcz E,Palmér M,Aman J,Berne C

更新日期：1997-10-01 00:00:00

abstract：:Left atrial (LA) structural, functional and mechanical changes have important role in development of diabetic cardiomyopathy and it was discovered that LA remodeling has important prognostic role in the patients with diabetes (DM). Previously the focus of echocardiographic studies in DM population was on the left vent...

journal_title：Acta diabetologica

authors： Tadic M,Cuspidi C

更新日期：2020-06-09 00:00:00

abstract：:To evaluate the effects of vasoactive intestinal peptide (VIP) on whole pancreatic blood flow and islet blood flow in the rat, anaesthetized adult rats were injected intravenously for 90 s with VIP (500 ng/kg body weight). Immediately after the injection, the whole pancreatic and islet blood flows were measured with a...

journal_title：Acta diabetologica

authors： Jansson L

更新日期：1994-06-01 00:00:00

abstract：:For many diabetic patients, years of blood glucose self-monitoring (SM) with readings taken several times daily is an inevitable aspect of insulin therapy. We investigated whether SM from abdominal skin might be an alternative to the established fingertip method. A total of 63 diabetic patients and 16 nondiabetic volu...

journal_title：Acta diabetologica

authors： Holstein A,Thiessen E,Kaufmann N,Plaschke A,Egberts EH

更新日期：2002-06-01 00:00:00

abstract：:Administration of exogenous insulin for the treatment of diabetes is often accompanied by the development of insulin antibodies (IA). These antibodies may affect the patient's requirement for insulin by acting as an insulin binding reservoir. The improvement of insulin purification in the 1970s and the development of ...

journal_title：Acta diabetologica

authors： Oak S,Phan TH,Gilliam LK,Hirsch IB,Hampe CS

更新日期：2010-06-01 00:00:00

abstract：AIMS:Glucose-dependent insulinotropic polypeptide (GIP) is released primarily from the proximal small intestine and glucagon-like peptide-1 (GLP-1) from the more distal small intestine and colon. Their relative importance to the incretin effect in health has been contentious in the past, although it now appears that GI...

journal_title：Acta diabetologica

authors： Marathe CS,Pham H,Marathe JA,Trahair LG,Huynh L,Wu T,Phillips LK,Rayner CK,Nauck MA,Horowitz M,Jones KL

更新日期：2020-05-01 00:00:00

abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

journal_title：Acta diabetologica

authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

更新日期：2020-04-01 00:00:00

abstract：:The objective is to assess the effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats. Male Wistar rats, 8-week-old, were categorized into four groups, which were the control (n = 9), diabetes (n = 9), infliximab-treated diabetes (n = 10), and FR167653-treated diabetes (n = 9) groups...

journal_title：Acta diabetologica

authors： Moriwaki Y,Inokuchi T,Yamamoto A,Ka T,Tsutsumi Z,Takahashi S,Yamamoto T

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Circulating levels of TNF alpha receptor 1 (TNFR1) and 2 (TNFR2) are associated with increased long-term mortality and impaired kidney function. AIM:To study association between circulating levels of TNFR1 and TNFR2 and short-term mortality in patients with diabetes and dyspnea. POPULATION AND METHODS:Pati...

journal_title：Acta diabetologica

authors： Wändell P,Carlsson AC,Larsson A,Melander O,Wessman T,Ärnlöv J,Ruge T

更新日期：2020-10-01 00:00:00

abstract：:The proinflammatory lysophosphatidic acid (LPA) is a potent activator of several transcriptional factors and signaling pathways and a potent modulator of genes involved in inflammation, angiogenesis and fibrosis. This study was conducted to measure the levels of LPA and LPA-producing enzymes, autotaxin (ATX) and acylg...

journal_title：Acta diabetologica

authors： Abu El-Asrar AM,Mohammad G,Nawaz MI,Siddiquei MM,Kangave D,Opdenakker G

更新日期：2013-06-01 00:00:00

abstract：:Although reactive oxygen species (ROS) contribute to glucose intolerance induced by the renin-angiotensin system (RAS) is well documented, the role of the newly discovered pathway of RAS, angiotensin (Ang)-(1-7)/Mas axis, in this process remains unknown. Here, we examined the effect of Ang-(1-7) on oxidative stress an...

journal_title：Acta diabetologica

authors： Liu C,Lv XH,Li HX,Cao X,Zhang F,Wang L,Yu M,Yang JK

更新日期：2012-08-01 00:00:00

abstract：:Aim To summarize, critically review, and interpret the evidence related to the systematic reviews on health literacy (HL) amongst type 2 diabetes mellitus (T2DM). Methods The methodology for this study consisted of a systematic review of systematic reviews, using the PRISMA statement and flowchart to select studies, a...

journal_title：Acta diabetologica

authors： Caruso R,Magon A,Baroni I,Dellafiore F,Arrigoni C,Pittella F,Ausili D

更新日期：2018-01-01 00:00:00

abstract：:This study was aimed at the assessment of incidence of malignancies in type 2 diabetic patients treated with different sulphonylureas. A matched case-control study was performed. Cases were 195 diabetic patients aged 69.0 +/- 9.2 years who had an incident malignancy. Controls were 195 diabetic patients, unaffected by ...

journal_title：Acta diabetologica

authors： Monami M,Lamanna C,Balzi D,Marchionni N,Mannucci E

更新日期：2009-12-01 00:00:00

abstract：:This 64-week prospective cohort trial evaluated the effects of 20-mg oestradiol implants, replaced every 4 months, in healthy postmenopausal women aged 45-65 years. Of 20 implant and 14 control subjects who remained in the trial at 32 weeks, 13 implant and seven controls continued to 64 weeks, with no baseline differe...

journal_title：Acta diabetologica

authors： Hansen RD,Raja C,Baber RJ,Lieberman D,Allen BJ

更新日期：2003-10-01 00:00:00

abstract：AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...

journal_title：Acta diabetologica

authors： Luo W,Yu Y,Wang H,Liu K,Wang Y,Huang M,Xuan C,Li Y,Qi J

更新日期：2020-12-01 00:00:00

abstract：:To define whether reference values for bioimpedance analysis (BIA) can be predicted in healthy individuals, individual characteristics and BIA variables (resistance index=height(2)/parallel resistance and reactance index= height(2)/parallel reactance) were evaluated in non-obese healthy individuals: 863 men and 769 wo...

journal_title：Acta diabetologica

authors： Bellizzi V,Scalfi L,Terracciano V,Marra M,Di Iorio B

更新日期：2003-10-01 00:00:00