Long-term fat-feeding-induced insulin resistance in normal NMRI mice: postreceptor changes of liver, muscle and adipose tissue metabolism resembling those of type 2 diabetes.

abstract：:In the present study our interests focused on the evaluation of a high capacity assay (MEIA) which allows true insulin determinations in the absence of cross-reactivity with proinsulin-like molecules. This method was compared to a commercially available radioimmunoassay (RIA) for insulin determination. As the latter g...

journal_title：Acta diabetologica

authors： Monti LD,Sandoli EP,Phan VC,Piatti PM,Costa S,Secchi A,Pozza G

更新日期：1995-03-01 00:00:00

abstract：AIMS:To investigate the short-term effects of intravitreal ranibizumab on retinal vessel functionality in patients with diabetic macular edema (DME) by Dynamic Vessel Analyzer (DVA). METHODS:Patients presenting with DME were enrolled in the study. All patients underwent a complete ophthalmic evaluation, including opti...

journal_title：Acta diabetologica

authors： Benatti L,Corvi F,Tomasso L,Darvizeh F,La Spina C,Querques L,Bandello F,Querques G

更新日期：2017-01-01 00:00:00

abstract：:To evaluate the role of insulin resistance and beta cell function to increasing fasting plasma glucose (FPG), 1,272 Chinese subjects (18-80 years of age) were divided into normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), combined glucose intolerance (CGI), and type 2 di...

journal_title：Acta diabetologica

authors： Bi Y,Zhu D,Jing Y,Hu Y,Feng W,Shen S,Tong G,Shen X,Yu T,Song D,Yang D

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Circulating levels of TNF alpha receptor 1 (TNFR1) and 2 (TNFR2) are associated with increased long-term mortality and impaired kidney function. AIM:To study association between circulating levels of TNFR1 and TNFR2 and short-term mortality in patients with diabetes and dyspnea. POPULATION AND METHODS:Pati...

journal_title：Acta diabetologica

authors： Wändell P,Carlsson AC,Larsson A,Melander O,Wessman T,Ärnlöv J,Ruge T

更新日期：2020-10-01 00:00:00

abstract：AIMS:Diabetic ketoacidosis (DKA) at diabetes diagnosis is a dangerous yet potentially preventable condition. Young age, low socioeconomic status, and low parental education have been found to be associated with increased risk of DKA. We aimed to evaluate the impact of religious affiliation on presentation with DKA at t...

journal_title：Acta diabetologica

authors： Gruber N,Reichman B,Lerner-Geva L,Pinhas-Hamiel O

更新日期：2015-04-01 00:00:00

abstract：AIMS:The importance of diabetes-related distress for the treatment of diabetes is emphasised in national and international guidelines recommending routinely screening for psychosocial problems. Data of investigations regarding diabetes-related distress on primary care are rare in Germany though most people with diabete...

journal_title：Acta diabetologica

authors： Kuniss N,Rechtacek T,Kloos C,Müller UA,Roth J,Burghardt K,Kramer G

更新日期：2017-05-01 00:00:00

abstract：:Sourdough bread has been reported to improve glucose metabolism in healthy subjects. In this study postprandial glycaemic and insulinaemic responses were evaluated in subjects with impaired glucose tolerance (IGT) who had a meal containing sourdough bread leavened with lactobacilli, in comparison to a reference meal c...

journal_title：Acta diabetologica

authors： Maioli M,Pes GM,Sanna M,Cherchi S,Dettori M,Manca E,Farris GA

更新日期：2008-06-01 00:00:00

abstract：:Fasting glucose and oral glucose tolerance test (OGTT) criteria for glucose homeostasis were compared in a cross-sectional cluster, community study in Accra, Ghana. A total of 4636 subjects without prior diagnosis of diabetes had fasting plasma glucose, 2-hour OGTT and measurement of cardiovascular risk factors. Mean ...

journal_title：Acta diabetologica

authors： Amoah AG

更新日期：2002-04-01 00:00:00

abstract：:The relationship between insulin responses to glucose and to arginine was studied in non-obese women with previous gestational diabetes (PGD). One group, n = 10, had normal glucose tolerance (NGT) by WHO criteria and another, n = 8, had impaired glucose tolerance (IGT). A third group of women without PGD, n = 12, was ...

journal_title：Acta diabetologica

authors： Alvarsson M,Wajngot A,Efendic S,Grill V

更新日期：1995-06-01 00:00:00

abstract：AIMS:Lipohypertrophy (LH) represents the most common skin-related complication associated with insulin therapy. Our aim is to estimate the prevalence of LH among insulin-treated patients, to identify its association with errors in insulin injection technique and storage, and the correlation between LH, risk of hypoglyc...

journal_title：Acta diabetologica

authors： Pozzuoli GM,Laudato M,Barone M,Crisci F,Pozzuoli B

更新日期：2018-01-01 00:00:00

abstract：AIMS:To assess the time-dependent effect of sleep quality on diabetes and coronary artery disease (CAD) incidence among young adults. METHODS:Incident rates of diabetes and CAD during a mean follow-up of 6.4 ± 4.1 years were assessed among 26,023 men (mean age 30.9 ± 5.6 years) of the Metabolic Lifestyle and Nutrition...

journal_title：Acta diabetologica

authors： Twig G,Shina A,Afek A,Derazne E,Tzur D,Cukierman-Yaffe T,Shechter-Amir D,Gerstein HC,Tirosh A

更新日期：2016-04-01 00:00:00

abstract：:The aim of this study was to evaluate lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes, and then to establish whether moderate doses of nonenzymatic antioxidant vitamin E play a role in the antioxidant defence system in diabetic pregnant rats and their offspring. The study group con...

journal_title：Acta diabetologica

authors： Kinalski M,Sledziewski A,Telejko B,Zarzycki W,Kinalska I

更新日期：2000-01-01 00:00:00

abstract：:The aim of this study was to assess the effectiveness and safety of intracavernous injections of a four-drug vasoactive mixture in diabetic patients with organic impotence. A group of 60 diabetic patients with either pure neurogenic, pure vasculogenic or mixed neurovasculogenic impotence were treated with intracaverno...

journal_title：Acta diabetologica

authors： Montorsi F,Guazzoni G,Bergamaschi F,Zucconi M,Rigatti P,Pizzini G,Miani A,Pozza G

更新日期：1994-04-01 00:00:00

abstract：:Genetic markers may be used to improve the prediction of insulin-dependent diabetes mellitus (type 1) in individuals with islet autoantibodies. In order to develop a risk assessment strategy for the Lombardy region of northern Italy based on genetic and immunological markers, we analyzed HLA DQA1 and DQB1 alleles in 6...

journal_title：Acta diabetologica

authors： Lampasona V,Ferrari M,Bonifacio E,Pastore MR,Carrera P,Sergi A,Genovese S,Trucco M,Dorman J,Bosi E

更新日期：1995-10-01 00:00:00

abstract：:Hemoglobin A1c (HbA1c) has been recommended as an optional method for diagnosing diabetes. The impact of HbA1c on the diagnosis of diabetes has not been evaluated in China, a country with the greatest number of people with diabetes in the world. Hence, we aim to examine how well HbA1c performs as compared with fasting...

journal_title：Acta diabetologica

authors： Sun X,Du T,Huo R,Xu L

更新日期：2014-01-01 00:00:00

abstract：:The purification of large numbers of human pancreatic islets remains one of the limiting factors in islet transplantation. This paper describes and validates a method for accurately and reproducibly determining the density of islets and exocrine tissue in pancreatic digest on the basis of their isopycnic distribution ...

journal_title：Acta diabetologica

authors： Robertson GS,Chadwick DR,Contractor H,James RF,Bell PR,London NJ

更新日期：1993-01-01 00:00:00

abstract：:Diabetes mellitus and hyperglycaemia are both independent risk factors (RF) for cardiovascular (CV) events and increased general and CV mortality. Type 2 diabetes, which is often associated with obesity, hypertension and dyslipidaemia, is accompanied by an up to fourfold increase in the incidence of acute coronary hea...

journal_title：Acta diabetologica

authors： Beltramello G,Manicardi V,Mazzuoli F,Rivellese A,Associazione Medici Diabetologi (AMD), Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO), Federazione delle Associazioni dei Dirigenti Ospedalieri Internisti (FADOI) and Societa` Italia

更新日期：2013-12-01 00:00:00

abstract：:Consistent with the postulated role of oxidative stress in the etiology of late diabetic complications, pharmacological interventions based on biological antioxidants have been suggested. The aim of the present study was to investigate the effect of dietary supplementation with the pyridoindole antioxidant stobadine o...

journal_title：Acta diabetologica

authors： Stefek M,Sotnikova R,Okruhlicova L,Volkovova K,Kucharska J,Gajdosik A,Gajdosikova A,Mihalova D,Hozova R,Tribulova N,Gvozdjakova A

更新日期：2000-01-01 00:00:00

abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...

journal_title：Acta diabetologica

authors： Shalitin S,Ben-Ari T,Yackobovitch-Gavan M,Tenenbaum A,Lebenthal Y,de Vries L,Phillip M

更新日期：2014-04-01 00:00:00

abstract：AIM:High glucose-induced oxidative stress has been suggested as one of the mediators of endothelial damage in diabetes. The major endothelial protein, endoglin, has been found overexpressed in the vessels during pathological situations, but little is known about its relation to diabetic vascular complications. To clari...

journal_title：Acta diabetologica

authors： La Sala L,Pujadas G,De Nigris V,Canivell S,Novials A,Genovese S,Ceriello A

更新日期：2015-06-01 00:00:00

abstract：:We report the results of bone mineral density (BMD) measurements in type 2 diabetic patients, in comparison to healthy controls. In this prospective study, a total of 277 subjects (aged 30-60 years) with type 2 diabetes mellitus, outpatients at the Cukurova Medical School Hospital, were evaluated for BMD at L(1)-L(4) ...

journal_title：Acta diabetologica

authors： Sert M,Tetiker T,Kirim S,Soyupak S,Canataroğlu A,Koçak M

更新日期：2003-06-01 00:00:00

abstract：AIMS:Radiolabeled Exendin-4 has been proposed as suitable imaging marker for pancreatic beta cell mass quantification mediated by Glucagon-like peptide-1 receptor (GLP-1R). However, noticeable species variations in basal pancreatic uptake as well as uptake reduction degree due to selective beta cell ablation were obser...

journal_title：Acta diabetologica

authors： Eriksson O,Rosenström U,Selvaraju RK,Eriksson B,Velikyan I

更新日期：2017-11-01 00:00:00

abstract：:In the present study, we investigated whether the ameliorating effect of aminoguanidine on diabetes-related proteinuria and nephropathy is associated with glomerular basement membrane heparan sulphate contents. STZ-induced diabetic rats developed proteinuria (at the tenth week: diabetic rats, 713 +/- 418 mg protein pe...

journal_title：Acta diabetologica

authors： Unlüçerçi YM,Bekpinar S,Seferoglu G

更新日期：2000-01-01 00:00:00

abstract：:Diabetes mellitus, the most common serious metabolic disorder, is characterized by functional and structural changes in the peripheral and central nervous systems. Glial cells provide structural and metabolic support for retinal neurons. During diabetes, one of the early pathogenic events is retinal glial reactivity. ...

journal_title：Acta diabetologica

authors： Baydas G,Tuzcu M,Yasar A,Baydas B

更新日期：2004-09-01 00:00:00

abstract：:The duration of diabetes before puberty is not considered relevant to the future development of complications. To evaluate the effects of diabetes on the neural retina, we analysed macular function by steady-state focal electroretinography in 20 prepubescent diabetic children without vascular retinopathy and in 39 sex...

journal_title：Acta diabetologica

authors： Greco AV,Di Leo MA,Caputo S,Falsini B,Porciatti V,Marietti G,Ghirlanda G

更新日期：1994-06-01 00:00:00

abstract：:The effect of the insulinotropic gut hormone glucagon-like-peptide-1 (GLP-1) was studied on the residual insulin capacity of prediabetic nonobese diabetic (NOD) mice, a model of insulin-dependent diabetes mellitus (type 1). This was done using isolated pancreas perfusion and dynamic islet perifusion. Prediabetes was d...

journal_title：Acta diabetologica

authors： Linn T,Schneider K,Göke B,Federlin K

更新日期：1996-03-01 00:00:00

abstract：:Our aim was to compare the effects of an intermediate acting human insulin (NPH) and a long-acting insulin analog, insulin glargine, in insulin naïve type 2 diabetes patients, stratified by the type of hyperglycemia (fasting or postprandial type). Based on different action profiles, we hypothesized that patients havin...

journal_title：Acta diabetologica

authors： Vähätalo MA,Viikari J,Rönnemaa T

更新日期：2014-04-01 00:00:00

abstract：:Post-prandial hyperglycemia is considered a relevant therapeutic target in type 2 diabetic patients, and it could represent per se an independent risk factor for diabetic complications. Aim of the present systematic review is to collect and summarize evidence from observational studies on the relationship between post...

journal_title：Acta diabetologica

authors： Mannucci E,Monami M,Lamanna C,Adalsteinsson JE

更新日期：2012-08-01 00:00:00

abstract：AIMS:Type 2 diabetes (DM2) is associated to oxidative modifications of high-density lipoproteins (HDL), which can interfere with their function. Pioglitazone has proved effective in raising HDL cholesterol (HDL-C) and lowering small dense low-density lipoprotein (LDL), but no clinical studies have examined its effect o...

journal_title：Acta diabetologica

authors： Sartore G,Chilelli NC,Seraglia R,Ragazzi E,Marin R,Roverso M,Cosma C,Vaccaro O,Burlina S,Lapolla A

更新日期：2019-05-01 00:00:00

abstract：:The recent efforts in the study of fetal compartments could help us to a better recognition of the proper fetal growth and well being. Fat content correlates directly with energy stores. Fat mass and lean body mass is often used in the nutritional assessment of the individual. Moreover chromosomal abnormalities may be...

journal_title：Acta diabetologica

authors： Valensise H,Larciprete G,Arduini D,De Lorenzo A

更新日期：2003-10-01 00:00:00