Early selective neuroretinal disorder in prepubertal type 1 (insulin-dependent) diabetic children without microvascular abnormalities.

abstract：:Cytomegalovirus (CMV) infects 40 % of the world population and has been suggested to be associated with diabetes; however, no prospective study has ever examined diabetes mortality associated with the infection. A cohort of 14,404 non-diabetic adult participants aged 17-90 years from the Third National Health and Nutr...

journal_title：Acta diabetologica

authors： Mendy A,Gasana J,Vieira ER,Diallo H

更新日期：2014-10-01 00:00:00

abstract：AIMS:Fat accumulation in the liver and in the muscle results in hepatic and muscle insulin resistance and has been associated with increased cardiovascular risk. It is unclear whether the individual role of hepatic and muscle insulin resistance in the onset of dyslipidaemia is observed in nonalcoholic fatty liver disea...

journal_title：Acta diabetologica

authors： Privitera G,Spadaro L,Alagona C,Calanna S,Piro S,Rabuazzo AM,Purrello F

更新日期：2016-06-01 00:00:00

abstract：:We analysed the risk factors associated with diabetic complications in the cohort of patients assisted by a type 2 diabetes mellitus (T2DM) shared-care program. We analysed registry data from 16,136 T2DM patients. Of them, 4,781 had microangiopathy, 3,469 CV events. They were 70.5 ± 17.1 years old, 50% were male, dise...

journal_title：Acta diabetologica

authors： Ciardullo AV,Daghio MM,Bevini M,Feltri G,Novi D,Fattori G,Borsari S,Donato CD

更新日期：2010-12-01 00:00:00

abstract：:Sourdough bread has been reported to improve glucose metabolism in healthy subjects. In this study postprandial glycaemic and insulinaemic responses were evaluated in subjects with impaired glucose tolerance (IGT) who had a meal containing sourdough bread leavened with lactobacilli, in comparison to a reference meal c...

journal_title：Acta diabetologica

authors： Maioli M,Pes GM,Sanna M,Cherchi S,Dettori M,Manca E,Farris GA

更新日期：2008-06-01 00:00:00

abstract：:Bacterial endotoxins have been associated with chronic inflammation and the development and progression of diabetic nephropathy. We hypothesized that subjects with high serum lipopolysaccharide activity also carry remains of bacterial DNA in their system. Serum-derived bacterial DNA clones were isolated and identified...

journal_title：Acta diabetologica

authors： Peräneva L,Fogarty CL,Pussinen PJ,Forsblom C,Groop PH,Lehto M

更新日期：2013-06-01 00:00:00

abstract：:Rosiglitazone often results in weight gain. We hypothesized that rosiglitazone may modulate circulating levels of ghrelin and peptide YY(3-36) and this modulation may be related to weight-gaining effect of this agent. This study was designed as an open-label, randomized, controlled trial of 3-month duration. Women wit...

journal_title：Acta diabetologica

authors： Berberoglu Z,Yazici AC,Bayraktar N,Demirag NG

更新日期：2012-12-01 00:00:00

abstract：:The objective of this study was to verify the impact of various sports on body cell mass (BCM). Ninety-eight male subjects, 17-33 years of age, participated in the study. The sample included athletes from three professional Italian football (soccer) teams, representing three different divisions (A, n=16; B, n=14; and ...

journal_title：Acta diabetologica

authors： Andreoli A,Melchiorri G,Brozzi M,Di Marco A,Volpe SL,Garofano P,Di Daniele N,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：:Aim of this study was to formulate an index for glucose effectiveness (Sg), SgIo, based on 3-point (0, 30 and 120 min) 75 g oral glucose tolerance test (OGTT). The equation for SgI(O) was developed in the Chikuma cohort (n = 502). Firstly, post-loading plasma glucose without insulin action and Sg (PPG-without insulin ...

journal_title：Acta diabetologica

authors： Nagasaka S,Kusaka I,Yamashita K,Funase Y,Yamauchi K,Katakura M,Ishibashi S,Aizawa T

更新日期：2012-12-01 00:00:00

abstract：:Post-prandial hyperglycemia is considered a relevant therapeutic target in type 2 diabetic patients, and it could represent per se an independent risk factor for diabetic complications. Aim of the present systematic review is to collect and summarize evidence from observational studies on the relationship between post...

journal_title：Acta diabetologica

authors： Mannucci E,Monami M,Lamanna C,Adalsteinsson JE

更新日期：2012-08-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has an important role in the endocrine pancreas. Multiple researches have shown that even in the insulin resistance phase, there are many abnormalities in islets morphology and function. This study aimed at investigating the effects of RAS blockade on the islets function in rats with...

journal_title：Acta diabetologica

authors： Yuan L,Li X,Li J,Li HL,Cheng SS

更新日期：2013-08-01 00:00:00

abstract：:The original report on the microencapsulation of islets of Langerhans used sodium alginate and poly-L-lysine (PLL) to form the capsules. Although several alternative materials have subsequently been used with vary-mg degrees of success, it is those studies using islets encapsulated in alginate-PLL-alginate which are r...

journal_title：Acta diabetologica

authors： Clayton HA,James RF,London NJ

更新日期：1993-01-01 00:00:00

abstract：:To determine the impact of glargine insulin therapy with different nutritional models on key parameters of diabetes including quality of life, behavior in children and adolescents with type 1 diabetes. Age, duration of diabetes, HbA1c, anthropometric data and episodes of severe hypoglycemia were taken from patients' c...

journal_title：Acta diabetologica

authors： Goksen D,Darcan S,Buyukinan M,Köse T,Erermis S,Coker M

更新日期：2008-03-01 00:00:00

abstract：:Preliminary evidence from trials with the HMG-CoA reductase inhibitors (statins), simvastatin and pravastatin, suggests that aggressive treatment of diabetic dyslipidaemia will reduce coronary events. Questions regarding the prevention of cardiovascular events in diabetic patients are now being addressed in prospectiv...

journal_title：Acta diabetologica

authors： Crespin SR

更新日期：2001-01-01 00:00:00

abstract：AIMS:We sought to investigate temporal trends in prediabetes prevalence among US adolescents using two definitions and evaluate relationships with obesity and a MetS-severity score. METHODS:We evaluated data from 5418 non-Hispanic white, non-Hispanic black, and Hispanic adolescents aged 12-19 participating in the Nati...

journal_title：Acta diabetologica

authors： Lee AM,Fermin CR,Filipp SL,Gurka MJ,DeBoer MD

更新日期：2017-04-01 00:00:00

abstract：:Overload of reactive oxygen species during diabetes is known to impair cellular homeostasis and to promote deterioration of membrane function in the organism. The aim of the present study was to examine the effect of dietary supplementation with the pyridoindole atioxidant stobadine on functional properties of the ren...

journal_title：Acta diabetologica

authors： Vrbjar N,Strelková S,Stefek M,Kyselová Z,Gajdosíková A

更新日期：2004-12-01 00:00:00

abstract：AIM:Infection of a diabetic foot ulcer (DFU) is common. More than the half of DFUs become infected and 15-20% of them necessitate amputation in course of treatment. Diabetic foot infection (DFI) is therefore the major cause for non-traumatic lower limb amputation in Germany. Prompt and effective treatment of DFI is man...

journal_title：Acta diabetologica

authors： Dörr S,Freier F,Schlecht M,Lobmann R

更新日期：2020-09-17 00:00:00

abstract：:Diabetic neuropathy is a significant complication of chronic diabetes. We wished to discover whether we were successfully identifying patients who had developed neuropathic problems. Specifically, Diabetologists are traditionally poor at asking about erectile dysfunction (ED) and patients themselves are not always for...

journal_title：Acta diabetologica

authors： Grant PS,Lipscomb D

更新日期：2009-12-01 00:00:00

abstract：:The purpose of this study was to determine the feasibility of a flexible multiple daily insulin (FMDI) regimen in routine pediatric diabetes care by comparing HbA(1c), body mass index (BMI), and episodes of severe hypoglycemia (SH) before and after initiation of FMDI therapy. Data from 44 patients (2-16 years old), on...

journal_title：Acta diabetologica

authors： Alemzadeh R,Palma-Sisto P,Parton E,Totka J,Kirby M

更新日期：2003-09-01 00:00:00

abstract：:To examine longitudinally the effect of diabetes on bone structure and metabolism, we measured bone mineral density (BMD) and turnover markers in 26 type 1 (mean age 49 years) and 27 type 2 (mean age 65 years) diabetic patients without known osteoporosis from a community-based sample at baseline and 5 years later. In ...

journal_title：Acta diabetologica

authors： Hamilton EJ,Rakic V,Davis WA,Paul Chubb SA,Kamber N,Prince RL,Davis TM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Emerging adulthood is a challenging period for diabetes management. Our aim was to determine whether a dedicated transition clinic for emerging adults with type 1 diabetes can improve glycemic control and visit attendance. METHODS:An observational study of 53 emerging adults (30 males) treated during 2010-2...

journal_title：Acta diabetologica

authors： Levy-Shraga Y,Elisha N,Ben-Ami M,Boyko V,Lerner-Geva L,Ziv T,Konvalina N,Cohen O,Pinhas-Hamiel O

更新日期：2016-02-01 00:00:00

abstract：AIMS:Maternal type 2 diabetes (T2D) can result in adverse pathological outcomes to both the mother and fetus. The present study aimed to investigate the pathological effects of maternal T2D on the gene expression patterns and functions of fetal human umbilical vein endothelial cells (HUVECs), a representative of fetal ...

journal_title：Acta diabetologica

authors： Sultan S

更新日期：2019-01-01 00:00:00

abstract：AIMS:To assess the risk of adverse neonatal outcomes in women with gestational diabetes (GDM) by identifying subgroups of women at higher risk to recognize the characteristics most associated with an excess of risk. METHODS:Observational, retrospective, multicenter study involving consecutive women with GDM. To identi...

journal_title：Acta diabetologica

authors： Pintaudi B,Fresa R,Dalfrà M,Dodesini AR,Vitacolonna E,Tumminia A,Sciacca L,Lencioni C,Marcone T,Lucisano G,Nicolucci A,Bonomo M,Napoli A,STRONG Study Collaborators.

更新日期：2018-12-01 00:00:00

abstract：AIM:To assess the association between alcohol consumption and/or cigarette smoking with other unhealthy behaviors and clinical cardiovascular risk factors in youth with type 1 diabetes. METHODS:Two hundred and twenty-eight youth with type 1 diabetes (age 13-19 years) were consecutively enrolled in three Regional Pedia...

journal_title：Acta diabetologica

authors： Valerio G,Mozzillo E,Zito E,De Nitto E,Maltoni G,Marigliano M,Zucchini S,Maffeis C,Franzese A

更新日期：2019-12-01 00:00:00

abstract：:MicroRNAs (miRNAs) play a crucial role in the pathogenesis of type 2 diabetes (T2D); they regulate several metabolic pathways including insulin secretion, glucose homeostasis, so their potential as biomarkers of diagnosis and prognosis has became increasingly appreciated. In this study, we explore serum miRNA profiles...

journal_title：Acta diabetologica

authors： Yang Z,Chen H,Si H,Li X,Ding X,Sheng Q,Chen P,Zhang H

更新日期：2014-10-01 00:00:00

abstract：:This 64-week prospective cohort trial evaluated the effects of 20-mg oestradiol implants, replaced every 4 months, in healthy postmenopausal women aged 45-65 years. Of 20 implant and 14 control subjects who remained in the trial at 32 weeks, 13 implant and seven controls continued to 64 weeks, with no baseline differe...

journal_title：Acta diabetologica

authors： Hansen RD,Raja C,Baber RJ,Lieberman D,Allen BJ

更新日期：2003-10-01 00:00:00

abstract：:To evaluate ex vivo/in vitro the binding and dissociation characteristics and the level of crossreactivity of insulin antibodies and insulin autoantibodies directed to three different insulin molecules (human, bovine and porcine insulin). In this study sera from 17 diabetic patients were included, who were exclusively...

journal_title：Acta diabetologica

authors： Jaeger C,Winter S,Eckhard M,Hardt P,Brendel MD,Bretzel RG

更新日期：2008-09-01 00:00:00

abstract：AIMS:To evaluate the methodological quality of systematic reviews (SRs), and summarize evidence of important outcomes from dipeptidyl peptidase-4 inhibitors (DPP4-I) in treating type 2 diabetes mellitus (T2DM). METHODS:We included SRs of DPP4-I for the treatment of T2DM until January, 2018 by searching the Cochrane Li...

journal_title：Acta diabetologica

authors： Ling J,Ge L,Zhang DH,Wang YF,Xie ZL,Tian JH,Xiao XH,Yang KH

更新日期：2019-01-01 00:00:00

abstract：AIMS:Glucose-dependent insulinotropic polypeptide (GIP) is released primarily from the proximal small intestine and glucagon-like peptide-1 (GLP-1) from the more distal small intestine and colon. Their relative importance to the incretin effect in health has been contentious in the past, although it now appears that GI...

journal_title：Acta diabetologica

authors： Marathe CS,Pham H,Marathe JA,Trahair LG,Huynh L,Wu T,Phillips LK,Rayner CK,Nauck MA,Horowitz M,Jones KL

更新日期：2020-05-01 00:00:00

abstract：AIMS:Diabetic ketoacidosis (DKA) at diabetes diagnosis is a dangerous yet potentially preventable condition. Young age, low socioeconomic status, and low parental education have been found to be associated with increased risk of DKA. We aimed to evaluate the impact of religious affiliation on presentation with DKA at t...

journal_title：Acta diabetologica

authors： Gruber N,Reichman B,Lerner-Geva L,Pinhas-Hamiel O

更新日期：2015-04-01 00:00:00

abstract：:Few studies were performed to evaluate the prevalence of latent autoimmune diabetes in adults (LADA) and the difference of chronic complications between LADA, T1DM, and T2DM in Korean. The aim of this study is to establish the prevalence of LADA in a diabetic clinic of Soonchunhyang University hospital and to compare ...

journal_title：Acta diabetologica

authors： Roh MO,Jung CH,Kim BY,Mok JO,Kim CH

更新日期：2013-04-01 00:00:00