Effects of 20-mg oestradiol implant therapy on bone mineral density, fat distribution and muscle mass in postmenopausal women.

abstract：:Pancreatic volume and fat content might be associated with β-cell function or insulin resistance (IR). We investigated the difference in pancreatic volume and fat content between age- and body mass index (BMI)-matched normal subjects and patients with having different durations of type 2 diabetes (T2D). We compared pa...

journal_title：Acta diabetologica

authors： Lim S,Bae JH,Chun EJ,Kim H,Kim SY,Kim KM,Choi SH,Park KS,Florez JC,Jang HC

更新日期：2014-10-01 00:00:00

abstract：:Cardiovascular risk is determined by multiple risk factors, all of which greatly increase the chance of morbidity and mortality. So-called "normal" levels of these factors are not biologically normal, so current strategy is based on estimations of a person's global cardiovascular risk, and then using appropriate combi...

journal_title：Acta diabetologica

authors： Sleight P

更新日期：2005-04-01 00:00:00

abstract：:The objective of this study is to explore the mechanism of oxidative stress induced by intermittent high glucose in porcine iliac endothelial cells (PIECs). The PIECs were exposed to intermittent or constant high glucose for 3 or 6 days, and the mean fluorescent intensity (MFI) was measured via intracellular reactive ...

journal_title：Acta diabetologica

authors： Ge QM,Dong Y,Zhang HM,Su Q

更新日期：2010-12-01 00:00:00

abstract：AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...

journal_title：Acta diabetologica

authors： Luo W,Yu Y,Wang H,Liu K,Wang Y,Huang M,Xuan C,Li Y,Qi J

更新日期：2020-12-01 00:00:00

abstract：:Serum gamma-glutamyl transferase (gamma-GT), a marker of oxidative stress, predicts morbidity and mortality from cardiovascular disease. Plasma total homocysteine (tHcy), a pro-oxidant and also an independent risk factor for cardiovascular disease, correlates with gamma-GT among some populations. It is not known wheth...

journal_title：Acta diabetologica

authors： Sakuta H,Suzuki T,Ito T

更新日期：2007-12-01 00:00:00

abstract：:The aim of this study was to compare the efficacy of treatment with insulin alone, insulin plus acarbose, insulin plus metformin, or insulin plus rosiglitazone in type 2 diabetic subjects who were previously on insulin monotherapy, and to evaluate the effects of these treatments on cardiovascular risk factors includin...

journal_title：Acta diabetologica

authors： Yilmaz H,Gursoy A,Sahin M,Guvener Demirag N

更新日期：2007-12-01 00:00:00

abstract：:The aim was to investigate the long-term incidence of proliferative diabetic retinopathy (PDR), and progression and regression of diabetic retinopathy (DR) and associated risk factors in young Danish patients with Type 1 diabetes mellitus. In 1987-89, a pediatric cohort involving approximately 75 % of all children wit...

journal_title：Acta diabetologica

authors： Broe R,Rasmussen ML,Frydkjaer-Olsen U,Olsen BS,Mortensen HB,Peto T,Grauslund J

更新日期：2014-01-01 00:00:00

abstract：AIMS:To define the possible effect of diabetic conditions on megakaryocytes, the long-know precursors of platelets and lately characterized modulator of hematopoietic stem quiescence-activation transition. METHODS:Megakaryoblastic MEG-01 cell culture and TPO/SCF/IL-3-induced differentiation of human umbilical blood mo...

journal_title：Acta diabetologica

authors： Wang B,Yu J,Wang T,Shen Y,Lin D,Xu X,Wang Y

更新日期：2018-05-01 00:00:00

abstract：AIMS:Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its effect on intestinal homeostasis remains unknown. METHODS:This st...

journal_title：Acta diabetologica

authors： Wang H,Tang W,Zhang P,Zhang Z,He J,Zhu D,Bi Y

更新日期：2020-04-01 00:00:00

abstract：:The aim of this study was to investigate the influence of homocysteine (hcy) levels on endothelial function by the method of brachial artery ultrasonography and their relation with microvascular complications in type 2 diabetes mellitus (T2DM) patients without macrovascular disease. Fifty-nine T2DM patients with a mea...

journal_title：Acta diabetologica

authors： Karabag T,Kaya A,Temizhan A,Koç F,Yavuz S,Cam S

更新日期：2007-06-01 00:00:00

abstract：:Cytomegalovirus (CMV) infects 40 % of the world population and has been suggested to be associated with diabetes; however, no prospective study has ever examined diabetes mortality associated with the infection. A cohort of 14,404 non-diabetic adult participants aged 17-90 years from the Third National Health and Nutr...

journal_title：Acta diabetologica

authors： Mendy A,Gasana J,Vieira ER,Diallo H

更新日期：2014-10-01 00:00:00

abstract：:Urinary angiotensin-converting enzyme (ACE) and urinary N-acetyl-beta-D-glucosaminidase (NAG) were measured after a 5-year interval in 38 non-azotemic type 2 diabetic patients. Of these patients at baseline, 16 had nil nephropathy, 15 had incipient nephropathy, and 7 had overt nephropathy. During the follow-up, 6 and ...

journal_title：Acta diabetologica

authors： Miyauchi E,Hosojima H,Morimoto S

更新日期：1995-10-01 00:00:00

abstract：AIMS:The purpose of this study was to investigate the mechanism of vascular endothelial cell apoptosis induced by acute blood glucose fluctuation. METHODS:Thirty rats were assigned to three groups: normal saline (SAL group), constant high glucose (CHG group) and acute blood glucose fluctuation (AFG) group. Other forty...

journal_title：Acta diabetologica

authors： Wu N,Shen H,Wang Y,He B,Zhang Y,Bai Y,Du R,Du Q,Han P

更新日期：2017-08-01 00:00:00

abstract：AIM:Infection of a diabetic foot ulcer (DFU) is common. More than the half of DFUs become infected and 15-20% of them necessitate amputation in course of treatment. Diabetic foot infection (DFI) is therefore the major cause for non-traumatic lower limb amputation in Germany. Prompt and effective treatment of DFI is man...

journal_title：Acta diabetologica

authors： Dörr S,Freier F,Schlecht M,Lobmann R

更新日期：2020-09-17 00:00:00

abstract：:Considering that changes in exercise routines might have relevance in treatment of adolescents with type 1 diabetes mellitus, we sought to assess whether spontaneous modifications to weekly exercise habits might occur in these patients and whether such variations would be accompanied by alterations in autonomic profil...

journal_title：Acta diabetologica

authors： Lucini D,Zuccotti GV,Scaramuzza A,Malacarne M,Gervasi F,Pagani M

更新日期：2013-06-01 00:00:00

abstract：:We hypothesize that type 2 diabetic patients with different phenotypes may show different response to incretin-based therapies. Therefore, we tested whether the presence of metabolic syndrome (MS) influences glycemic response to these drugs. We prospectively followed 211 patients, treated with the GLP-1 analog exenati...

journal_title：Acta diabetologica

authors： Fadini GP,de Kreutzenberg SV,Gjini R,Avogaro A

更新日期：2011-09-01 00:00:00

abstract：AIMS:Type 2 diabetes (T2D) is a metabolic disorder requiring intensive self-care to maintain optimal glycemic control. Sleep disturbance is common in T2D patients and likely impairs glycemic control. Our aim was to examine the relationship between sleep disturbance and self-care in adults with T2D. METHODS:This study ...

journal_title：Acta diabetologica

authors： Zhu B,Quinn L,Kapella MC,Bronas UG,Collins EG,Ruggiero L,Park CG,Fritschi C

更新日期：2018-09-01 00:00:00

abstract：:Cyclosporin and methotrexate administration induces remission of type 1 diabetes mellitus. Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). Its usefulness was limited by its toxicity. Since methotrexate (mtx) and cyclo synergistically inhibit ...

journal_title：Acta diabetologica

authors： Sobel DO,Henzke A,Abbassi V

更新日期：2010-09-01 00:00:00

abstract：:Hyperglycaemia caused by stress and inflammation is common during critical illness. We hypothesised that a latent glucose metabolism disturbance contributes to development of hyperglycaemia and that those patients have increased risk for diabetes. We included patients with sepsis, acute coronary syndrome and acute hea...

journal_title：Acta diabetologica

authors： Gornik I,Vujaklija A,Lukić E,Madžarac G,Gašparović V

更新日期：2010-12-01 00:00:00

abstract：:Concentrations of soluble receptors for tumor necrosis factor (p55 and p75) strongly correlate with clinical stage and progression of infectious diseases, and may be useful in monitoring autoimmune diseases. However, the role of soluble TNF receptors in insulin-dependent diabetes mellitus (type 1 DM) is not clear. We ...

journal_title：Acta diabetologica

authors： Kulseng B,Vatten L,Espevik T

更新日期：1999-06-01 00:00:00

abstract：:For many diabetic patients, years of blood glucose self-monitoring (SM) with readings taken several times daily is an inevitable aspect of insulin therapy. We investigated whether SM from abdominal skin might be an alternative to the established fingertip method. A total of 63 diabetic patients and 16 nondiabetic volu...

journal_title：Acta diabetologica

authors： Holstein A,Thiessen E,Kaufmann N,Plaschke A,Egberts EH

更新日期：2002-06-01 00:00:00

abstract：AIMS:The anti-inflammatory effects of the polyphenol resveratrol in patients with type 2 diabetes mellitus (T2DM) are controversial. Its role on pentraxin 3 (PTX3) concentrations, a human acute phase protein, has never been evaluated. Our aim was to determine whether a two-dosage resveratrol supplementation (500 and 40...

journal_title：Acta diabetologica

authors： Bo S,Ponzo V,Evangelista A,Ciccone G,Goitre I,Saba F,Procopio M,Cassader M,Gambino R

更新日期：2017-05-01 00:00:00

abstract：:This study was aimed at the assessment of incidence of malignancies in type 2 diabetic patients treated with different sulphonylureas. A matched case-control study was performed. Cases were 195 diabetic patients aged 69.0 +/- 9.2 years who had an incident malignancy. Controls were 195 diabetic patients, unaffected by ...

journal_title：Acta diabetologica

authors： Monami M,Lamanna C,Balzi D,Marchionni N,Mannucci E

更新日期：2009-12-01 00:00:00

abstract：AIMS:To evaluate the efficacy and safety of intravitreal dexamethasone implant (DEX-implant) for diabetic macular edema (DME) in real-life practice with an extended follow-up for up to 5 year. METHODS:This multicentric retrospective study reviewed 227 eyes of 152 patients with DME treated by DEX-implant. Main outcome ...

journal_title：Acta diabetologica

authors： Mathis T,Lereuil T,Abukashabah A,Voirin N,Sudhalkar A,Bilgic A,Denis P,Dot C,Kodjikian L

更新日期：2020-12-01 00:00:00

abstract：AIMS:Observational studies indicated that resting heart rate (RHR) was associated with diabetes mellitus (DM) risk; however, it remains unclear whether the association between RHR and DM is causal. We aimed to examine whether there was causal association of RHR with DM risk. METHODS:A prospective study including 16,20...

journal_title：Acta diabetologica

authors： Long T,Wang J,Han X,Wang F,Hu H,Yu C,Yuan J,Yao P,Wei S,Wang Y,Liang Y,Miao X,Zhang X,Guo H,Zheng D,Tang Y,Yang H,Huang S,He M

更新日期：2019-09-01 00:00:00

abstract：AIMS:Hypoglycaemia represents a critical burden with clinical and social consequences in the management of diabetes. Serum uric acid (SUA) has been associated with cardiovascular diseases (CVD), but no conclusive findings are available nowadays in patients suffering from hypoglycaemia. We investigated whether SUA level...

journal_title：Acta diabetologica

authors： Bonaventura A,Gallo F,Carbone F,Liberale L,Maggi D,Sacchi G,Dallegri F,Montecucco F,Cordera R

更新日期：2018-04-01 00:00:00

abstract：:We report the results of bone mineral density (BMD) measurements in type 2 diabetic patients, in comparison to healthy controls. In this prospective study, a total of 277 subjects (aged 30-60 years) with type 2 diabetes mellitus, outpatients at the Cukurova Medical School Hospital, were evaluated for BMD at L(1)-L(4) ...

journal_title：Acta diabetologica

authors： Sert M,Tetiker T,Kirim S,Soyupak S,Canataroğlu A,Koçak M

更新日期：2003-06-01 00:00:00

abstract：AIMS:The relationship between bisphenol A (BPA) and diabetes remains controversial. This study aims to investigate whether serum BPA level could predict the 5-year incidence of type 2 diabetes (T2D). METHODS:A nested case-control study was performed among Chinese who participated in the environment, inflammation and m...

journal_title：Acta diabetologica

authors： Shu X,Tang S,Peng C,Gao R,Yang S,Luo T,Cheng Q,Wang Y,Wang Z,Zhen Q,Hu J,Li Q

更新日期：2018-04-01 00:00:00

abstract：AIMS:High glycemic variability (GV) is the major indication for islet transplantation (IT) in patients with type 1 diabetes (T1D). The actual criteria used to assess graft function do not consider GV improvement. Our study aimed to describe GV indices' evolution in T1D patients who benefited from IT during the TRIMECO ...

journal_title：Acta diabetologica

authors： Jalbert M,Zheng F,Wojtusciszyn A,Forbes F,Bonnet S,Skaare K,Benhamou PY,Lablanche S,TRIMECO Study Group.

更新日期：2020-03-01 00:00:00

abstract：AIMS:Observational studies and meta-analyses of randomized trials on dipeptidyl peptidase-4 inhibitors (DPP4i) reported discordant results on the risk of malignancies with this class of drugs. Aim of the present meta-analysis is the assessment of the effect of DPP4i treatment on the incidence of different types of canc...

journal_title：Acta diabetologica

authors： Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

更新日期：2020-06-01 00:00:00