Effects of type 2 diabetes mellitus on plasma fatty acid composition and cholesterol content of erythrocyte and leukocyte membranes.

abstract：:Anti-myeloperoxidase (anti-MPO) antibodies were detected in 34 of 88 (38%) patients with type 1 diabetes mellitus but in only 3 of 55 (5.7%) healthy subjects and in 4 of 20 patients with autoimmune disease. Specificity of anti-MPO antibodies was assessed by MPO inhibition studies. No relationship was found between the...

journal_title：Acta diabetologica

authors： Accardo-Palumbo A,Triolo G,Giardina E,Carbone MC,Ferrante A,Triolo G

更新日期：1996-07-01 00:00:00

abstract：AIMS:Observational studies indicated that resting heart rate (RHR) was associated with diabetes mellitus (DM) risk; however, it remains unclear whether the association between RHR and DM is causal. We aimed to examine whether there was causal association of RHR with DM risk. METHODS:A prospective study including 16,20...

journal_title：Acta diabetologica

authors： Long T,Wang J,Han X,Wang F,Hu H,Yu C,Yuan J,Yao P,Wei S,Wang Y,Liang Y,Miao X,Zhang X,Guo H,Zheng D,Tang Y,Yang H,Huang S,He M

更新日期：2019-09-01 00:00:00

abstract：:The effect of a phenacyl imidazolium compound (LY177507 or Proglycosyn, Eli Lilly) on the direct (glucose-->glucose-6-phosphate-->glycogen) and indirect (three-carbon compounds-->glucose-6-phosphate-->glycogen) pathways of liver glycogen synthesis was studied in conscious rats. [1-13C]Glucose (99% enriched) was infuse...

journal_title：Acta diabetologica

authors： Cline GW,Greenawalt K,Shulman GI

更新日期：1993-01-01 00:00:00

abstract：:The objective of this study was to verify the impact of various sports on body cell mass (BCM). Ninety-eight male subjects, 17-33 years of age, participated in the study. The sample included athletes from three professional Italian football (soccer) teams, representing three different divisions (A, n=16; B, n=14; and ...

journal_title：Acta diabetologica

authors： Andreoli A,Melchiorri G,Brozzi M,Di Marco A,Volpe SL,Garofano P,Di Daniele N,De Lorenzo A

更新日期：2003-10-01 00:00:00

abstract：AIMS:The main objective of this study was to estimate the incidence rate and prevalence of pediatric type 1 diabetes mellitus (T1DM; population 0-18 years of age) in the northeastern Italian region Friuli Venezia Giulia and to characterize the subjects affected by the disease. METHODS:This was a retrospective populati...

journal_title：Acta diabetologica

authors： Valent F,Candido R,Faleschini E,Tonutti L,Tortul C,Zanatta M,Zanette G,Zanier L

更新日期：2016-08-01 00:00:00

abstract：AIMS:To evaluate the patients' perceptions of telemedicine visits during COVID-19 lockdown and their level of anxiety about COVID and diabetic foot (DF). METHODS:In May 2020, we contacted by phone all the patients who underwent in March and April to remote monitoring visits for DF during the lockdown for COVID-19, wit...

journal_title：Acta diabetologica

authors： Iacopi E,Pieruzzi L,Goretti C,Piaggesi A

更新日期：2021-01-13 00:00:00

abstract：:Pancreatic volume and fat content might be associated with β-cell function or insulin resistance (IR). We investigated the difference in pancreatic volume and fat content between age- and body mass index (BMI)-matched normal subjects and patients with having different durations of type 2 diabetes (T2D). We compared pa...

journal_title：Acta diabetologica

authors： Lim S,Bae JH,Chun EJ,Kim H,Kim SY,Kim KM,Choi SH,Park KS,Florez JC,Jang HC

更新日期：2014-10-01 00:00:00

abstract：:Correct classification of diabetic patients in adulthood at the time of diagnosis is often difficult. Some may be initially diagnosed as having non-insulin-dependent diabetes mellitus and be treated with diet and/or oral hypoglycaemic agents (OHA) but later require insulin treatment. Islet cell antibodies and antibodi...

journal_title：Acta diabetologica

authors： Hatziagelaki E,Jaeger C,Maeser E,Bretzel RG,Federlin K

更新日期：1996-12-01 00:00:00

abstract：AIM:To assess the association between alcohol consumption and/or cigarette smoking with other unhealthy behaviors and clinical cardiovascular risk factors in youth with type 1 diabetes. METHODS:Two hundred and twenty-eight youth with type 1 diabetes (age 13-19 years) were consecutively enrolled in three Regional Pedia...

journal_title：Acta diabetologica

authors： Valerio G,Mozzillo E,Zito E,De Nitto E,Maltoni G,Marigliano M,Zucchini S,Maffeis C,Franzese A

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Emerging adulthood is a challenging period for diabetes management. Our aim was to determine whether a dedicated transition clinic for emerging adults with type 1 diabetes can improve glycemic control and visit attendance. METHODS:An observational study of 53 emerging adults (30 males) treated during 2010-2...

journal_title：Acta diabetologica

authors： Levy-Shraga Y,Elisha N,Ben-Ami M,Boyko V,Lerner-Geva L,Ziv T,Konvalina N,Cohen O,Pinhas-Hamiel O

更新日期：2016-02-01 00:00:00

abstract：:Hypertriglyceridaemia is associated with insulin resistance of both lipid and glucose metabolism. It is not known whether the insulin resistance affects both glucose oxidation and glycogen formation. To study the oxidative and non-oxidative pathways of non-esterified fatty acids (NEFA) and glucose metabolism, eight ma...

journal_title：Acta diabetologica

authors： Saloranta C,Groop L,Ekstrand A,Franssila-Kallunki A,Taskinen MR

更新日期：1994-04-01 00:00:00

abstract：:Autonomic nervous dysfunction is considered to be one of the mechanisms of metabolic syndrome (MetS). The aim of this study is to investigate whether resting heart rate, a marker of autonomic nervous dysfunction, is a predictor of MetS in apparently healthy non-obese [body mass index (BMI) <25 kg/m(2)] Japanese men. T...

journal_title：Acta diabetologica

authors： Oda E,Aizawa Y

更新日期：2014-02-01 00:00:00

abstract：AIMS:Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase in SIRT-1 expression affects histone 3 acetylation at the 56 lysine residue (H3K56ac) in T2DM patients randomly selected to receive ei...

journal_title：Acta diabetologica

authors： Bo S,Togliatto G,Gambino R,Ponzo V,Lombardo G,Rosato R,Cassader M,Brizzi MF

更新日期：2018-04-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has an important role in the endocrine pancreas. Multiple researches have shown that even in the insulin resistance phase, there are many abnormalities in islets morphology and function. This study aimed at investigating the effects of RAS blockade on the islets function in rats with...

journal_title：Acta diabetologica

authors： Yuan L,Li X,Li J,Li HL,Cheng SS

更新日期：2013-08-01 00:00:00

abstract：:The aim of this study was to evaluate the prevalence of thyroid autoantibodies and clinical significance of thyroid autoimmunity in children with the diagnosis of diabetes mellitus type 1. The study group comprised 222 children all with newly diagnosed diabetes mellitus type 1 (122 boys) with a mean age 9.92 +/- 4.5 y...

journal_title：Acta diabetologica

authors： Machnica L,Osior A,Jarosz-Chobot P,Deja G,Polanska J,Otto-Buczkowska E

更新日期：2008-03-01 00:00:00

abstract：:Hemoglobin A1c (HbA1c) has been recommended as an optional method for diagnosing diabetes. The impact of HbA1c on the diagnosis of diabetes has not been evaluated in China, a country with the greatest number of people with diabetes in the world. Hence, we aim to examine how well HbA1c performs as compared with fasting...

journal_title：Acta diabetologica

authors： Sun X,Du T,Huo R,Xu L

更新日期：2014-01-01 00:00:00

abstract：AIMS:Besides energy supply, β-hydroxybutyrate (BHB) acts as a bioactive molecule to play multiple protective roles, even in diabetes and its complications. The aim of this study was to investigate the antagonizing effects of BHB against diabetic glomerulosclerosis and the underlying mechanism. METHODS:Male Sprague-Daw...

journal_title：Acta diabetologica

authors： Luo W,Yu Y,Wang H,Liu K,Wang Y,Huang M,Xuan C,Li Y,Qi J

更新日期：2020-12-01 00:00:00

abstract：:In late twentieth century, Ruderman and Reaven showed that insulin resistance might be fundamental to metabolic syndrome (MetS) which means a constellation of obesity-related metabolic derangements predisposing to type 2 diabetes and cardiovascular disease. In 2001, user-friendly National Cholesterol Education Program...

journal_title：Acta diabetologica

authors： Oda E

更新日期：2012-04-01 00:00:00

abstract：:Selective loss of capillary pericytes occurs early and specifically in diabetic retinopathy. We have investigated whether blood derivatives from patients with long-term type 1 (insulin-dependent) diabetes and no retinopathy differ from those with retinopathy and/or non-diabetic controls in their ability to stimulate D...

journal_title：Acta diabetologica

authors： Williams FM,Dosso AA,Kohner EM,Porta M

更新日期：1993-01-01 00:00:00

abstract：AIMS:Medication adherence and persistence are important determinants of treatment success in type 2 diabetes mellitus (T2DM). This systematic review and meta-analysis evaluated the real-world adherence, persistence, and in-class switching among patients with T2DM prescribed dipeptidyl peptidase-4 (DPP4) inhibitors. ME...

journal_title：Acta diabetologica

authors： Ogundipe O,Mazidi M,Chin KL,Gor D,McGovern A,Sahle BW,Jermendy G,Korhonen MJ,Appiah B,Ademi Z,De Bruin ML,Liew D,Ofori-Asenso R

更新日期：2021-01-01 00:00:00

abstract：:Diabetic neuropathy is a significant complication of chronic diabetes. We wished to discover whether we were successfully identifying patients who had developed neuropathic problems. Specifically, Diabetologists are traditionally poor at asking about erectile dysfunction (ED) and patients themselves are not always for...

journal_title：Acta diabetologica

authors： Grant PS,Lipscomb D

更新日期：2009-12-01 00:00:00

abstract：:Cyclosporin and methotrexate administration induces remission of type 1 diabetes mellitus. Administration of high-dose cyclosporin (cyclo) has been demonstrated to induce remission of type 1 diabetes mellitus (T1D). Its usefulness was limited by its toxicity. Since methotrexate (mtx) and cyclo synergistically inhibit ...

journal_title：Acta diabetologica

authors： Sobel DO,Henzke A,Abbassi V

更新日期：2010-09-01 00:00:00

abstract：:The effect of sucrose in the diet of children and adolescents with type I diabetes on long-term metabolic control was studied. For a mean observation period of 83 (range 42-127) days, a diet containing 5% of total calories as refined sugar was recommended to 11 children (group A, mean age 15.0, SD 5.4 years), while an...

journal_title：Acta diabetologica

authors： Schwingshandl J,Rippel S,Unterluggauer M,Borkenstein M

更新日期：1994-12-01 00:00:00

abstract：:Considering that changes in exercise routines might have relevance in treatment of adolescents with type 1 diabetes mellitus, we sought to assess whether spontaneous modifications to weekly exercise habits might occur in these patients and whether such variations would be accompanied by alterations in autonomic profil...

journal_title：Acta diabetologica

authors： Lucini D,Zuccotti GV,Scaramuzza A,Malacarne M,Gervasi F,Pagani M

更新日期：2013-06-01 00:00:00

abstract：:Overload of reactive oxygen species during diabetes is known to impair cellular homeostasis and to promote deterioration of membrane function in the organism. The aim of the present study was to examine the effect of dietary supplementation with the pyridoindole atioxidant stobadine on functional properties of the ren...

journal_title：Acta diabetologica

authors： Vrbjar N,Strelková S,Stefek M,Kyselová Z,Gajdosíková A

更新日期：2004-12-01 00:00:00

abstract：:We have measured protein phosphatase (PP) activity in crude homogenates as well as in the total 105.000 x g supernatant and precipitate fractions from normal rat pancreatic islets. On the basis of the inhibition produced by either 1 nM or 1 microM okadaic acid, both PP1 and PP2A activity were present in crude islet ho...

journal_title：Acta diabetologica

authors： Gagliardino JJ,Rossi PF,García ME

更新日期：1997-03-01 00:00:00

abstract：AIMS:In patients with type 2 diabetes, non-alcoholic fatty liver disease (NAFLD) and liver fibrosis is frequent and presumably associated with increased cardiovascular disease risk and mortality. The objective was to investigate risk factors associated with hepatic fibrosis in patients with type 2 diabetes and NAFLD to...

journal_title：Acta diabetologica

authors： Mansour A,Mohajeri-Tehrani MR,Samadi M,Gerami H,Qorbani M,Bellissimo N,Poustchi H,Hekmatdoost A

更新日期：2019-11-01 00:00:00

abstract：:The aim of this study is to assess the impact of the internet-based upload blood glucose monitoring and therapy management system (Carelink(®)) in patients with type 1 diabetes. Diabetic patients treated with pump infusion for ≥3 months were prospectively randomized to use the CareLink(®) with (4 months) and without (...

journal_title：Acta diabetologica

authors： Shalitin S,Ben-Ari T,Yackobovitch-Gavan M,Tenenbaum A,Lebenthal Y,de Vries L,Phillip M

更新日期：2014-04-01 00:00:00

abstract：:The aim of the present work was to investigate the impact of gender on resting cerebral blood flow velocity and cerebrovascular reserve capacity among diabetic patients. Middle cerebral artery mean blood flow velocity (MCAV) was measured in 72 patients suffering from type 1 diabetes mellitus at rest and 5, 10, 15 and ...

journal_title：Acta diabetologica

authors： Fülesdi B,Limburg M,Oláh L,Bereczki D,Csiba L,Kollár J

更新日期：2001-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) infects 40 % of the world population and has been suggested to be associated with diabetes; however, no prospective study has ever examined diabetes mortality associated with the infection. A cohort of 14,404 non-diabetic adult participants aged 17-90 years from the Third National Health and Nutr...

journal_title：Acta diabetologica

authors： Mendy A,Gasana J,Vieira ER,Diallo H

更新日期：2014-10-01 00:00:00