Administration of first hospital antibiotics for community-acquired pneumonia: does timeliness affect outcomes?

abstract：PURPOSE OF REVIEW:Fungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide...

journal_title：Current opinion in infectious diseases

authors： Tacke D,Koehler P,Cornely OA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV infection profoundly impairs the immune mechanisms needed to control and clear Leishmania infection, and outcomes in patients with HIV-associated visceral leishmaniasis are poor. This review summarizes recent work describing the epidemiology, presentation and outcomes of HIV-associated visceral le...

journal_title：Current opinion in infectious diseases

authors： Jarvis JN,Lockwood DN

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Dolutegravir (DTG) is a second-generation integrase strand transfer inhibitor (InSTI) with an outstanding antiviral potency, good tolerability, good pharmacokinetic profile with a lack of major drug-drug interactions, and a barrier to resistance higher than the other compounds of the class (raltegravi...

journal_title：Current opinion in infectious diseases

authors： Blanco JL,Marcelin AG,Katlama C,Martinez E

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Clostridium difficile infection and Clostridium difficile-associated diarrhea (CDAD) are growing worldwide health threats. Recent studies have identified new host risk factors, diagnostic approaches and therapies of CDAD. The present review focuses on scientific papers published in the past 18 months ...

journal_title：Current opinion in infectious diseases

authors： DuPont HL,Garey K,Caeiro JP,Jiang ZD

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacillus Calmette-Guerin (BCG) vaccination has been performed since 1921, and remains the best method of preventing severe infections caused by Mycobacterium tuberculosis. Tuberculosis, in its various forms, remains a public health problem, and more than 100 countries continue BCG vaccination in an ef...

journal_title：Current opinion in infectious diseases

authors： Bellet JS,Prose NS

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Amphotericin B (AmpB) is considered the first-line treatment for visceral leishmaniasis in areas in which resistance to antimony is prevalent. This review describes recent advances in clinically available and novel drug delivery systems of AmpB to treat visceral leishmaniasis. RECENT FINDINGS:Over th...

journal_title：Current opinion in infectious diseases

authors： Mohamed-Ahmed AH,Brocchini S,Croft SL

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials. RECENT FINDINGS:At least three polyclonal and eight monoclonal antibody products have been tested in clinical tr...

journal_title：Current opinion in infectious diseases

authors： Beigel JH

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In industrialized countries avoidance of breastfeeding is among the cornerstones of prevention of mother-to-child transmission of HIV. Breastfeeding carries risk for HIV transmission but improves survival, whereas formula feeding carries zero risk for transmission but increased risk for mortality. We ...

journal_title：Current opinion in infectious diseases

authors： Coovadia H,Kindra G

更新日期：2008-02-01 00:00:00

abstract：:The past few years have seen important developments in understanding the epidemiological and virological characteristics of rotaviruses, and rapid progress has been made in rotavirus vaccine development, but further challenges remain before a vaccine is introduced into widespread use. The licensure of the first rotavi...

journal_title：Current opinion in infectious diseases

authors： Lynch M,Bresee JS,Gentsch JR,Glass RI

更新日期：2000-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Parasites and other infections have many effects on the gastrointestinal tract of individuals who are immunocompromised. Few reviews focus on parasitic infections, which are covered here. RECENT FINDINGS:The review first examines recent advances in our understanding of the taxonomy, diagnosis and tre...

journal_title：Current opinion in infectious diseases

authors： Lewthwaite P,Gill GV,Hart CA,Beeching NJ

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses the changing patterns of antimicrobial resistance in Salmonella. RECENT FINDINGS:Resistance to chloramphenicol, amicillin and cotrimoxazole is common in Salmonella Typhi and Paratyphi A in Asia and a few countries of Africa. In some countries, the isolation of multidrug resistan...

journal_title：Current opinion in infectious diseases

authors： Parry CM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Skin and soft tissue infections (SSTIs) in patients with hematological malignancies are frequent, but dedicated epidemiological studies are limited. The aim of this review is to provide updated description of the main etiological agents, differential diagnosis, and treatment. RECENT FINDINGS:In addit...

journal_title：Current opinion in infectious diseases

authors： Ungaro R,Mikulska M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Mucormycosis is an increasingly common fungal infection with an unacceptably high mortality despite first-line antifungal therapy. Iron acquisition is a critical step in the causative organisms' pathogenetic mechanism. Therefore, abrogation of fungal iron acquisition is a promising therapeutic strateg...

journal_title：Current opinion in infectious diseases

authors： Ibrahim AS,Spellberg B,Edwards J Jr

更新日期：2008-12-01 00:00:00

abstract：:The implementation of surveillance systems for HIV and of large cohort studies have allowed for the construction of models that more accurately describe the HIV epidemic. This review focuses on changes in the epidemiological pattern, and the effect of changes in behaviour and of antiretroviral therapy. ...

journal_title：Current opinion in infectious diseases

authors： Greco D

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Dengue is one of the most rapidly spreading vector-borne diseases in the world, with the incidence increasing 30-fold in the past 50 years. There are currently no licensed treatments or vaccines for dengue. This review covers the recent advances in our understanding of dengue pathogenesis, including h...

journal_title：Current opinion in infectious diseases

authors： Yacoub S,Mongkolsapaya J,Screaton G

更新日期：2013-06-01 00:00:00

abstract：:Herpes simplex virus persists in a latent form for the life of its host, periodically reactivating and often resulting in significant psychosocial distress for the patient. Currently no cure is available. Antiviral therapy is the main treatment modality, used either orally, intravenously, or topically to prohibit furt...

journal_title：Current opinion in infectious diseases

authors： Yeung-Yue KA,Brentjens MH,Lee PC,Tyring SK

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Viruses are an increasingly recognized cause of community-acquired pneumonia (CAP), but their exact role in nosocomial pneumonia is still debated. This review focuses on the role of viruses as a cause of nosocomial pneumonia. RECENT FINDINGS:Respiratory viruses may be responsible for healthcare-a...

journal_title：Current opinion in infectious diseases

authors： Luyt CE,Bréchot N,Chastre J

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to synopsize and highlight the recent subtle genetic changes in cholera causing toxigenic Vibrio cholerae with special reference to their virulence, integrating and conjugative elements and toxin-antitoxin systems. It is not intended to cover issues on the whole genome se...

journal_title：Current opinion in infectious diseases

authors： Das B,Pazhani GP,Sarkar A,Mukhopadhyay AK,Nair GB,Ramamurthy T

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:In hematopoietic cell transplant (HCT) recipients, paramyxovirus infections are major viral respiratory tract infections that, if they progress to lower respiratory tract infections, are associated with reduced survival rates in this population. There are important knowledge gaps regarding treatment d...

journal_title：Current opinion in infectious diseases

authors： Batista MV,El Haddad L,Chemaly RF

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review identifies trends in the study of interactions between Staphylococcus aureus and humans. When nasal colonization is in the neutral state, infection clearly represents a state of host-pathogen disbalance. The features leading from apparent homeostatic colonization to pathogenesis are identi...

journal_title：Current opinion in infectious diseases

authors： van Belkum A

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:As the evidence for two-drug regimens (2DR) for HIV treatment accumulates and 2DR start to enter consensus guidelines, this review covers the history, rationale and current evidence for 2DR in first-line and switch settings. RECENT FINDINGS:Until recently, most evidence for 2DR was for boosted protea...

journal_title：Current opinion in infectious diseases

authors： Waters L,Church H

更新日期：2020-02-01 00:00:00

abstract：:Efforts to reduce hospitalization or the length of stay are common topics in papers published last year. Chlamydia pneumoniae is now recognized worldwide as a common pathogen in community-acquired pneumonia. A great variation in the frequency of various pathogens is found in different countries, stressing the importan...

journal_title：Current opinion in infectious diseases

authors： Holmberg H

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Antibiotic resistance continues to rise, whereas development of new agents to counter it has slowed. A heightened need exists to maintain the effectiveness of currently available agents. This review focuses on the need for better antimicrobial stewardship, expected benefits of well designed antimicrob...

journal_title：Current opinion in infectious diseases

authors： Goff DA

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the epidemiology, strategies for early detection, and clinical management of infections caused by the most commonly found multidrug-resistant (MDR) Candida spp. RECENT FINDINGS:Increasing numbers of reports describing invasive infections by MDR Candida auris and Candida glabrata has been ...

journal_title：Current opinion in infectious diseases

authors： Colombo AL,Júnior JNA,Guinea J

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Hidradenitis suppurativa is a chronic or relapsing inflammatory cutaneous disorder manifested by recurrent formation of abscesses, fistulating sinus and scarring in the apocrine-gland-bearing skin. This review discusses the different aetiological theories and management opportunities. RECENT FINDINGS...

journal_title：Current opinion in infectious diseases

authors： Yazdanyar S,Jemec GB

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute exacerbations of chronic obstructive pulmonary disease were a poorly defined and understood entity. The application of better study designs and new research methodologies has shed considerable light on the pathogenesis of this common clinical syndrome. RECENT FINDINGS:Inflammation is an importa...

journal_title：Current opinion in infectious diseases

authors： Sethi S

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The recent sequencing of the whole genome of Malassezia globosa and M. restricta forms the basis for molecular epidemiology studies and instigates investigations into their respective virulence factors. Thus, reviewing current knowledge on Malassezia molecular typing methods would reveal the pros and ...

journal_title：Current opinion in infectious diseases

authors： Gaitanis G,Bassukas ID,Velegraki A

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This is a review of tafenoquine, a new antimalarial drug. Here we examine the recent literature supporting the use of tafenoquine and summarize the opportunities and challenges for its well tolerated use worldwide. RECENT FINDINGS:Tafenoquine was recently approved by the US Food and Drug Administrati...

journal_title：Current opinion in infectious diseases

authors： Chen V,Daily JP

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial stewardship is now recognized as a formal strategy for curbing the upward trend in antibiotic resistance. Literature on antimicrobial stewardship has focused on areas of strategic importance and operational delivery. A number of barriers have been recognized in the implementation of succ...

journal_title：Current opinion in infectious diseases

authors： Bal AM,Gould IM

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Toxoplasmosis in haematopoietic cell transplant (HCT) recipients is associated with high morbidity and mortality rates. Prophylaxis following HCT is recommended for high-risk pre-HCT toxoplasma-seropositive (pre-HCTSP) recipients. However, there is no agreement or consistency among programmes on wheth...

journal_title：Current opinion in infectious diseases

authors： Gajurel K,Dhakal R,Montoya JG

更新日期：2015-08-01 00:00:00