Breastfeeding to prevent HIV transmission in infants: balancing pros and cons.

abstract：PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...

journal_title：Current opinion in infectious diseases

authors： Hickman M,De Angelis D,Vickerman P,Hutchinson S,Martin NK

更新日期：2015-12-01 00:00:00

abstract：:Otitis media is a very common reason for the prescription of antibiotics in children. Antimicrobial therapy is mostly empirical, based on the knowledge of the frequency and susceptibility patterns of causative pathogens and of the penetration and other pharmacokinetic properties of several oral antibiotics. Pharmacoec...

journal_title：Current opinion in infectious diseases

authors： Paradisi F,Corti G

更新日期：1998-12-01 00:00:00

abstract：:Studies published within the past year have highlighted the potential morbidity associated with polyomaviruses and novel herpesviruses (e.g. human herpesvirus-6, 7 and -8). Although antiviral therapy has not been shown to be effective for polyomaviruses, attempts at management of human herpesvirus-6 and -8 infections ...

journal_title：Current opinion in infectious diseases

authors： Singh N

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:West Nile virus emerged recently in North America as a serious human and animal pathogen. This review summarizes the use of experimental infections with West Nile virus in diverse vertebrate species that have been used to answer fundamental questions about the host response, pathogenesis of West Nile ...

journal_title：Current opinion in infectious diseases

authors： Bowen RA,Nemeth NM

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Nontuberculous mycobacterial disease, especially pulmonary disease, is increasingly encountered by clinicians. Therapy of the most common nontuberculous mycobacterial pathogen, Mycobacterium avium complex, improved with the introduction of macrolide-containing regimens, but treatment for this and most...

journal_title：Current opinion in infectious diseases

authors： Griffith DE

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of both invasive fungal infections and respiratory mould infections is increasing and they cause significant costs, morbidity and mortality. Non-Aspergillus moulds are increasing as cause of lung infections in specific populations and new problems of susceptibility and resistance are app...

journal_title：Current opinion in infectious diseases

authors： Paiva JA,Pereira JM

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review describes the literature about the prevention of Staphylococcus aureus infections in surgery, published from August 2006 to January 2008, and puts it into perspective. RECENT FINDINGS:To prevent Staphylococcus aureus infections after surgical procedures, three methods were describe...

journal_title：Current opinion in infectious diseases

authors： van Rijen MM,Kluytmans JA

更新日期：2008-08-01 00:00:00

abstract：:The implementation of surveillance systems for HIV and of large cohort studies have allowed for the construction of models that more accurately describe the HIV epidemic. This review focuses on changes in the epidemiological pattern, and the effect of changes in behaviour and of antiretroviral therapy. ...

journal_title：Current opinion in infectious diseases

authors： Greco D

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Early treatment of invasive mold infections improves the outcome. Therapy is often delayed, however, because available diagnostic tools such as culture, microscopy and conventional radiology lack sensitivity; consequently, empirical initiation of antifungal therapy has been advocated, particularly for...

journal_title：Current opinion in infectious diseases

authors： Maertens J,Deeren D,Dierickx D,Theunissen K

更新日期：2006-12-01 00:00:00

abstract：:Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P. aeruginosa leads to progressive ...

journal_title：Current opinion in infectious diseases

authors： Brennan AL,Geddes DM

更新日期：2002-04-01 00:00:00

abstract：:Interleukin-10 is the most potent anti-inflammatory cytokine yet identified. It has multiple actions affecting the innate immune system as well as humoral and cellular immune responses. It occupies a pivotal role in the regulation of the immune response to microbial pathogens in health and disease. Knowledge gained in...

journal_title：Current opinion in infectious diseases

authors： Opal SM,Huber CE

更新日期：2000-06-01 00:00:00

abstract：PURPOSE OF REVIEW:It is now well established that cytokines play a critical role in the regulation of the immune system. Processes such as lymphoid development, differentiation, homeostasis, tolerance and memory are all regulated by cytokines that bind the type I family of cytokine receptors. Like the interferons, whic...

journal_title：Current opinion in infectious diseases

authors： Gadina M,Ferguson PR,Johnston JA

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The early treatment of invasive fungal infection is critical but is hampered by the non-specific nature of clinical and radiological signs and the insensitivity of current laboratory diagnostic methods. If mortality due to invasive fungal infection is to be reduced, new, preemptive therapeutic strateg...

journal_title：Current opinion in infectious diseases

authors： Jones BL,McLintock LA

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The world's population is becoming increasing mobile. Each mobile population (e.g. immigrants, refugees, travelers) has certain characteristics that determine public health risk and infectious disease burden. Refugees present unique challenges to public health officials and infectious disease speciali...

journal_title：Current opinion in infectious diseases

authors： Stauffer WM,Weinberg M

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to evaluate basic mechanisms, prevalence, risk factors, outcomes, and potential treatments of cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP). RECENT FINDINGS:In this review, we present a new model to evaluate the pathophysiology of cardiac disease in patie...

journal_title：Current opinion in infectious diseases

authors： Aliberti S,Ramirez JA

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent studies suggest that contemporary antibiotic dosing is unlikely to achieve best outcomes for critically ill patients because of extensive pharmacokinetic variability and altered pharmacodynamics. Dose adaptation is considered quite challenging because of unpredictable dose-exposure relationship...

journal_title：Current opinion in infectious diseases

authors： Parker SL,Sime FB,Roberts JA

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Dolutegravir (DTG) is a second-generation integrase strand transfer inhibitor (InSTI) with an outstanding antiviral potency, good tolerability, good pharmacokinetic profile with a lack of major drug-drug interactions, and a barrier to resistance higher than the other compounds of the class (raltegravi...

journal_title：Current opinion in infectious diseases

authors： Blanco JL,Marcelin AG,Katlama C,Martinez E

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacterial zoonoses are increasingly described in association with travel. Some bacterial zoonoses constitute important causes of post-travel illness. We focus on leptospirosis and rickettsiosis - the most common travel-associated bacterial zoonoses. RECENT FINDINGS:Leptospirosis is regarded to be the...

journal_title：Current opinion in infectious diseases

authors： Leshem E,Meltzer E,Schwartz E

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Climate change, deforestation, urbanization, and increased population mobility have made the risk of large outbreaks of yellow fever more likely than ever. Yellow fever vaccine production barely meets demands. In this review, we address the causes of the recent yellow fever outbreaks, why fractional d...

journal_title：Current opinion in infectious diseases

authors： Visser LG

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Modeling of antibiotic resistance in pathogenic bacteria responsible for human disease has developed considerably over the last decade. Herein, we summarize the main published studies to illustrate the contribution of models for understanding both within-host and population-based phenomena. We then su...

journal_title：Current opinion in infectious diseases

authors： Opatowski L,Guillemot D,Boëlle PY,Temime L

更新日期：2011-06-01 00:00:00

abstract：:Helicobacter pylori is a bacterium that colonizes the human stomach, especially during childhood. Although it has been studied intensively during the past decade, many controversies still exist on many important issues, including the clinical relevance of virulence factors, indications for treatment, recommended proce...

journal_title：Current opinion in infectious diseases

authors： Vandenplas Y

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute exacerbations of chronic obstructive pulmonary disease were a poorly defined and understood entity. The application of better study designs and new research methodologies has shed considerable light on the pathogenesis of this common clinical syndrome. RECENT FINDINGS:Inflammation is an importa...

journal_title：Current opinion in infectious diseases

authors： Sethi S

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance among Gram-negative microorganisms has alarmingly increased in the past 10 years worldwide. Infections caused by these microorganisms are difficult to treat, especially in critically ill patients.The present review examines how to accurately predict which patients carry a grea...

journal_title：Current opinion in infectious diseases

authors： Burillo A,Muñoz P,Bouza E

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize important papers concerning measles disease and measles-containing vaccines published in 2004. RECENT FINDINGS:Endemic measles has been successfully controlled in the Americas and, to a lesser extent, in Europe. This has been achieved with a high uptake of t...

journal_title：Current opinion in infectious diseases

authors： Elliman D,Sengupta N

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:For decades, healthcare workers have been known to be at risk from acquiring a variety of bloodborne pathogen infections as a result of occupational exposure. Primary prevention of exposures, as recommended by universal precautions guidelines, remains the cornerstone of protecting healthcare workers. ...

journal_title：Current opinion in infectious diseases

authors： Beekmann SE,Henderson DK

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on the epidemiology and cause of diarrheal illness in solid organ transplant and stem-cell transplant population recipients with a specific focus on the role of advanced multiplex technology in the diagnosis of diarrhea within this patient population. RECENT FINDINGS:A wide ran...

journal_title：Current opinion in infectious diseases

authors： Santoiemma PP,Ison MG,Angarone MP

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Clostridium difficile infection and Clostridium difficile-associated diarrhea (CDAD) are growing worldwide health threats. Recent studies have identified new host risk factors, diagnostic approaches and therapies of CDAD. The present review focuses on scientific papers published in the past 18 months ...

journal_title：Current opinion in infectious diseases

authors： DuPont HL,Garey K,Caeiro JP,Jiang ZD

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent developments in West Nile encephalitis. Because of the large number of individuals infected in the United States, an expanded spectrum of the disease has been recognized. Flaccid paralysis presenting as poliomyelitis-like syndrome is being increasingly recognized. RECENT F...

journal_title：Current opinion in infectious diseases

authors： Cunha BA

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the availability of new antifungals and improved antifungal formulations, there is a continued need for the development of new drugs to treat invasive fungal infections. In high-risk populations, including heavily immunocompromised patients, those with multiple comorbidities, and patients in i...

journal_title：Current opinion in infectious diseases

authors： Wiederhold NP,Patterson TF

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Human brucellosis is a neglected, underrecognized infection of widespread geographic distribution. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. This review describes new information regarding t...

journal_title：Current opinion in infectious diseases

authors： Rubach MP,Halliday JE,Cleaveland S,Crump JA

更新日期：2013-10-01 00:00:00