New advances in Clostridium difficile infection: changing epidemiology, diagnosis, treatment and control.

abstract：PURPOSE OF REVIEW:In contrast to patients at risk for hospital-acquired pneumonia or mechanically ventilated patients at risk for ventilator-associated pneumonia, healthcare-associated pneumonia is a relatively new clinical entity that includes a spectrum of adult patients who have close association with acute care hos...

journal_title：Current opinion in infectious diseases

authors： Craven DE

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent studies suggest that contemporary antibiotic dosing is unlikely to achieve best outcomes for critically ill patients because of extensive pharmacokinetic variability and altered pharmacodynamics. Dose adaptation is considered quite challenging because of unpredictable dose-exposure relationship...

journal_title：Current opinion in infectious diseases

authors： Parker SL,Sime FB,Roberts JA

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:For decades, healthcare workers have been known to be at risk from acquiring a variety of bloodborne pathogen infections as a result of occupational exposure. Primary prevention of exposures, as recommended by universal precautions guidelines, remains the cornerstone of protecting healthcare workers. ...

journal_title：Current opinion in infectious diseases

authors： Beekmann SE,Henderson DK

更新日期：2005-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the epidemiology, strategies for early detection, and clinical management of infections caused by the most commonly found multidrug-resistant (MDR) Candida spp. RECENT FINDINGS:Increasing numbers of reports describing invasive infections by MDR Candida auris and Candida glabrata has been ...

journal_title：Current opinion in infectious diseases

authors： Colombo AL,Júnior JNA,Guinea J

更新日期：2017-12-01 00:00:00

abstract：:Influenza continues to be a major health concern and there is always the threat of a pandemic due to the emergence of a viral strain new to the human population, as exemplified by the avian influenza A/H5N1 virus which was responsible for six deaths in Hong Kong last year. Data reported in the past year, based on in-v...

journal_title：Current opinion in infectious diseases

authors： Mendel DB,Roberts NA

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Rates of carbapenem-resistant Enterobacteriaceae (CRE), especially Klebsiella pneumoniae carbapenemase (KPC)-producing Gram-negatives, have increased worldwide. Infections caused by these organisms have been associated with a high mortality, which might be due in part to the limited availability of an...

journal_title：Current opinion in infectious diseases

authors： Munoz-Price LS,Quinn JP

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Modeling of antibiotic resistance in pathogenic bacteria responsible for human disease has developed considerably over the last decade. Herein, we summarize the main published studies to illustrate the contribution of models for understanding both within-host and population-based phenomena. We then su...

journal_title：Current opinion in infectious diseases

authors： Opatowski L,Guillemot D,Boëlle PY,Temime L

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The issue of whether the outcome of bacteremic pneumococcal infections is improved with the use of combination antibiotic therapy versus monotherapy is still not resolved. This review highlights recent studies that have addressed this issue. RECENT FINDINGS:Some studies have indicated benefit of comb...

journal_title：Current opinion in infectious diseases

authors： Feldman C,Anderson R

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to discuss the rationale of and current evidence for prolonged beta-lactam infusion in the management of Gram-negative infections. RECENT FINDINGS:Pharmacokinetic/pharmacodynamic (PK/PD) data from various in-vitro and in-vivo experimental studies conclusively support prolong...

journal_title：Current opinion in infectious diseases

authors： Abdul-Aziz MH,Portunato F,Roberts JA

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Co-infection with Plasmodium falciparum malaria and Epstein-Barr virus (EBV) are implicated in the cause of endemic Burkitt lymphoma (eBL), the most prevalent pediatric cancer in equatorial Africa. Although the causal association between EBV and eBL has been established, P. falciparum malaria's role i...

journal_title：Current opinion in infectious diseases

authors： Moormann AM,Snider CJ,Chelimo K

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Prion diseases such as Creutzfeldt-Jakob disease represent a unique infection control problem because prions exhibit an unusual resistance to conventional chemical and physical decontamination methods. This paper reviews the recent literature and provides recommendations for the prevention of nosocomi...

journal_title：Current opinion in infectious diseases

authors： Weber DJ,Rutala WA

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Schistosomiasis is a chronic and morbid disease that affects hundreds of millions of the poorest individuals in (sub)tropical regions, particularly sub-Saharan Africa. Just one drug, praziquantel (PZQ), is available. As discussed, efforts to expand mass drug administration programs may accelerate the ...

journal_title：Current opinion in infectious diseases

authors： Caffrey CR,Secor WE

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The emergence of 2009 pandemic H1N1 influenza A (pH1N1) has provided a unique challenge to influenza control in healthcare settings. We provide an overview of the early lessons from the 2009 pandemic. RECENT FINDINGS:The modes of influenza transmission and their contributions to the development of in...

journal_title：Current opinion in infectious diseases

authors： Carlson AL,Budd AP,Perl TM

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Several studies show that the number of FcgammaRI (CD64) on the surface of neutrophils increases in infections. However, in spite of increased research interest in recent years, there is no clear general view on the usability of neutrophil FcgammaRI in clinical infection diagnostics. This review tries...

journal_title：Current opinion in infectious diseases

authors： Nuutila J

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance o...

journal_title：Current opinion in infectious diseases

authors： Sood G,Parrish N

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The frequency and impact of viruses among intensive care unit (ICU) nonimmunocompromised patients remains controversial. This review analyzes their place as causal pathogens in ventilator-associated pneumonia, as well as their effects on ICU patients' outcomes. RECENT FINDINGS:Herpesviruses, namely h...

journal_title：Current opinion in infectious diseases

authors： Chiche L,Forel JM,Papazian L

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute gastroenteritis is one of the leading causes of morbidity and mortality in children in the developing world. With improvements in hygiene and sanitation, the burden of disease due to bacterial and parasitic infections has decreased and an increasing proportion of diarrhoea hospitalizations are a...

journal_title：Current opinion in infectious diseases

authors： Ramani S,Kang G

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Breast surgery is considered a clean surgical procedure; nevertheless, infection rates are often higher than those reported after other similarly considered clean surgeries (e.g., thyroid, hernia). Acute bacterial skin and soft tissue infections, mostly surgical site infections and implant-associated ...

journal_title：Current opinion in infectious diseases

authors： Corcione S,Lupia T,De Rosa FG

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on the recent developments in the epidemiology, burden of disease, diagnostic tests, and treatment of fascioliasis. RECENT FINDINGS:Recent epidemiologic data suggest that either the endemic areas are expanding or disease is being recognized in areas where it was not previously obs...

journal_title：Current opinion in infectious diseases

authors： Cabada MM,White AC Jr

更新日期：2012-10-01 00:00:00

abstract：:The implementation of surveillance systems for HIV and of large cohort studies have allowed for the construction of models that more accurately describe the HIV epidemic. This review focuses on changes in the epidemiological pattern, and the effect of changes in behaviour and of antiretroviral therapy. ...

journal_title：Current opinion in infectious diseases

authors： Greco D

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the potential new diagnostic tools for determining the cause of pneumonia in the setting of community-acquired infection after outlining the limitation of currently available tests. RECENT FINDINGS:A number of new tools are on the horizon with the potential to overcome the problems of exist...

journal_title：Current opinion in infectious diseases

authors： Basnayake TL,Waterer GW

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on recent developments on evaluation of 8-aminoquinoline analogs with broader efficacy and reduced toxicity, which would provide better drugs for treatment of protozoal infections. RECENT FINDINGS:The earlier efforts towards development of 8-aminoquinoline analogs have been direct...

journal_title：Current opinion in infectious diseases

authors： Tekwani BL,Walker LA

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses the changing patterns of antimicrobial resistance in Salmonella. RECENT FINDINGS:Resistance to chloramphenicol, amicillin and cotrimoxazole is common in Salmonella Typhi and Paratyphi A in Asia and a few countries of Africa. In some countries, the isolation of multidrug resistan...

journal_title：Current opinion in infectious diseases

authors： Parry CM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS:An upsurge in wild poliovirus type 1 cases in Pa...

journal_title：Current opinion in infectious diseases

authors： Bandyopadhyay AS,Macklin GR

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on the epidemiology and cause of diarrheal illness in solid organ transplant and stem-cell transplant population recipients with a specific focus on the role of advanced multiplex technology in the diagnosis of diarrhea within this patient population. RECENT FINDINGS:A wide ran...

journal_title：Current opinion in infectious diseases

authors： Santoiemma PP,Ison MG,Angarone MP

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Pneumocystis pneumonia (PCP) is a frequent opportunistic infection associated with a high mortality rate. PCP is of increasing importance in non-HIV immunocompromised patients, who present with severe respiratory distress with low fungal loads. Molecular detection of Pneumocystis in broncho-alveolar l...

journal_title：Current opinion in infectious diseases

authors： Guegan H,Robert-Gangneux F

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses recent developments that relate to the pathogenesis of severe malaria and its treatment, and also highlights the increase in the global burden of malaria and provides a summary of clinical trials of malaria vaccines. RECENT FINDINGS:Malaria, one of the world's most important par...

journal_title：Current opinion in infectious diseases

authors： Maitland K,Bejon P,Newton CR

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Particularities of the fetal immune response to infection cause a heightened inflammatory state that acts synergistically with microbial insult to induce damage. Proteomics offers the opportunity for detecting fetuses at risk of sepsis and neurological injury. RECENT FINDINGS:Molecular tools (16S-rRN...

journal_title：Current opinion in infectious diseases

authors： Buhimschi CS,Bhandari V,Han YW,Dulay AT,Baumbusch MA,Madri JA,Buhimschi IA

更新日期：2009-06-01 00:00:00

abstract：:Bone marrow transplant recipients are at increased risk of a variety of infections from endogenous and exogenous sources. Various practices, including the use of prophylactic agents and a controlled environment are often employed in the name of infection control. Comparable data are lacking because of non-unified defi...

journal_title：Current opinion in infectious diseases

authors： Kusne S,Krystofiak S

更新日期：2001-08-01 00:00:00

abstract：:Helicobacter pylori is a bacterium that colonizes the human stomach, especially during childhood. Although it has been studied intensively during the past decade, many controversies still exist on many important issues, including the clinical relevance of virulence factors, indications for treatment, recommended proce...

journal_title：Current opinion in infectious diseases

authors： Vandenplas Y

更新日期：2001-06-01 00:00:00