Managing the risk of nosocomial transmission of prion diseases.

abstract：PURPOSE OF REVIEW:The recent sequencing of the whole genome of Malassezia globosa and M. restricta forms the basis for molecular epidemiology studies and instigates investigations into their respective virulence factors. Thus, reviewing current knowledge on Malassezia molecular typing methods would reveal the pros and ...

journal_title：Current opinion in infectious diseases

authors： Gaitanis G,Bassukas ID,Velegraki A

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update on the public health impact of food-related illness in light of recent high-profile outbreaks and advances in the methodology to estimate illness burden. It includes mainly literature from high-income countries, as burden of illness estimations have b...

journal_title：Current opinion in infectious diseases

authors： O'Brien SJ

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The review examines the changing causes and the investigation of infectious and noninfectious diarrhoea in individuals with HIV. RECENT FINDINGS:Despite the excellent prognosis conferred by combination antiretroviral therapy, diarrhoea is still common in HIV-positive individuals and is associated wit...

journal_title：Current opinion in infectious diseases

authors： Logan C,Beadsworth MB,Beeching NJ

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize recent developments in our understanding of the modifiable behavioural and biological factors contributing to the transmission of genital herpes simplex infection, and the limited data on the use of antiviral agents for reducing transmission risk in serodiscordan...

journal_title：Current opinion in infectious diseases

authors： Patel R

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on some of the recent advances in the understanding of HIV immunopathogenesis and the diagnosis and treatment of several autoimmune conditions associated with HIV in the era of potent antiretroviral therapy. RECENT FINDINGS:Chronic immune activation with progressive immune exhaust...

journal_title：Current opinion in infectious diseases

authors： Stratton R,Slapak G,Mahungu T,Kinloch-de Loes S

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Human brucellosis is a neglected, underrecognized infection of widespread geographic distribution. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. This review describes new information regarding t...

journal_title：Current opinion in infectious diseases

authors： Rubach MP,Halliday JE,Cleaveland S,Crump JA

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Necrotizing enterocolitis remains an enigmatic and potentially devastating condition with high morbidity and mortality. This review explores ways in which bacterial pathogens, together with gut microflora, influence the pathophysiology of necrotizing enterocolitis. Specifically, it examines the role o...

journal_title：Current opinion in infectious diseases

authors： Hammerman C,Kaplan M

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review risk-based pre-emptive treatment for adenovirus (ADV) based on quantitative PCR (qPCR) and to provide an update on clinical trials of brincidofovir (BCV) and ADV-specific cytotoxic T lymphocytes (ADV-CTLs). RECENT FINDINGS:ADV qPCR in various body compartments enables distinction of clinica...

journal_title：Current opinion in infectious diseases

authors： Lee YJ,Prockop SE,Papanicolaou GA

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:As physicians are confronted with a diversity of adverse events and variability in response to medication among patients, this review will focus on the available evidence regarding the impact of genetic variation on drug response. Specifically, variation in drug metabolizing enzymes such as the cytoch...

journal_title：Current opinion in infectious diseases

authors： Boffito M,Winston A,Owen A

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Streptococcus pneumoniae is a major cause of morbidity and mortality in the pediatric population. The development of increasing resistance to multiple classes of antibiotics is making treatment of infections due to this organism much more difficult. The ultimate impact of high-level antibiotic resista...

journal_title：Current opinion in infectious diseases

authors： Tan TQ

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Dolutegravir (DTG) is a second-generation integrase strand transfer inhibitor (InSTI) with an outstanding antiviral potency, good tolerability, good pharmacokinetic profile with a lack of major drug-drug interactions, and a barrier to resistance higher than the other compounds of the class (raltegravi...

journal_title：Current opinion in infectious diseases

authors： Blanco JL,Marcelin AG,Katlama C,Martinez E

更新日期：2018-06-01 00:00:00

abstract：:The sequence of the Treponema pallidum genome was completed in July 1998, yielding a wealth of new information regarding the enigmatic spirochete that causes syphilis and related treponematoses. By providing the sequences and predicted functions of over 1000 genes, the genome sequence will greatly facilitate research ...

journal_title：Current opinion in infectious diseases

authors： Norris SJ,Weinstock GM

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The frequency and impact of viruses among intensive care unit (ICU) nonimmunocompromised patients remains controversial. This review analyzes their place as causal pathogens in ventilator-associated pneumonia, as well as their effects on ICU patients' outcomes. RECENT FINDINGS:Herpesviruses, namely h...

journal_title：Current opinion in infectious diseases

authors： Chiche L,Forel JM,Papazian L

更新日期：2011-04-01 00:00:00

abstract：:Head lice is an old problem that won't go away. Infestation with the head louse Pediculus capitis is still common in school-aged children. The majority of information about this condition is based on anecdotal evidence. There is a definite need for the standardization of detection methods for diagnosis and epidemiolog...

journal_title：Current opinion in infectious diseases

authors： Figueroa JI

更新日期：2000-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance o...

journal_title：Current opinion in infectious diseases

authors： Sood G,Parrish N

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a history of inadequate treatments for cryptosporidiosis and a lack of understanding of the species that cause human disease. Against this background, we review the efficacy of antiparasitic agents, particularly nitazoxanide, which has led to increased treatment options, the potential for imm...

journal_title：Current opinion in infectious diseases

authors： Smith HV,Corcoran GD

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review offers an update on hepatitis A, B and E vaccines based on relevant literature published in 2011-2012. Hepatitis A and B vaccines have been commercially available for years; however, the development of the hepatitis E vaccine is still facing some challenges. RECENT FINDINGS:Current scient...

journal_title：Current opinion in infectious diseases

authors： Hendrickx G,Vorsters A,Van Damme P

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Hepatitis E, a disease transmitted by hepatitis E virus, is increasingly recognized as being indigenous to affluent, temperate-zone countries. Issues pertaining to disease acquisition and hepatitis E virus infection, particularly in Western countries, are reviewed and highlighted. RECENT FINDINGS:Cli...

journal_title：Current opinion in infectious diseases

authors： Teo CG

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the potential new diagnostic tools for determining the cause of pneumonia in the setting of community-acquired infection after outlining the limitation of currently available tests. RECENT FINDINGS:A number of new tools are on the horizon with the potential to overcome the problems of exist...

journal_title：Current opinion in infectious diseases

authors： Basnayake TL,Waterer GW

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:As the evidence for two-drug regimens (2DR) for HIV treatment accumulates and 2DR start to enter consensus guidelines, this review covers the history, rationale and current evidence for 2DR in first-line and switch settings. RECENT FINDINGS:Until recently, most evidence for 2DR was for boosted protea...

journal_title：Current opinion in infectious diseases

authors： Waters L,Church H

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vaccination in pregnancy boosts maternal vaccine-specific antibody concentration and therefore increases transplacental transfer of antibody to optimize protection of the infant. The purpose of this review is to describe what is known about placental transfer of antibody in the context of vaccination ...

journal_title：Current opinion in infectious diseases

authors： Calvert A,Jones CE

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Skin and soft tissue infections (SSTIs) in patients with hematological malignancies are frequent, but dedicated epidemiological studies are limited. The aim of this review is to provide updated description of the main etiological agents, differential diagnosis, and treatment. RECENT FINDINGS:In addit...

journal_title：Current opinion in infectious diseases

authors： Ungaro R,Mikulska M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In contrast to patients at risk for hospital-acquired pneumonia or mechanically ventilated patients at risk for ventilator-associated pneumonia, healthcare-associated pneumonia is a relatively new clinical entity that includes a spectrum of adult patients who have close association with acute care hos...

journal_title：Current opinion in infectious diseases

authors： Craven DE

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Schistosomiasis is a chronic and morbid disease that affects hundreds of millions of the poorest individuals in (sub)tropical regions, particularly sub-Saharan Africa. Just one drug, praziquantel (PZQ), is available. As discussed, efforts to expand mass drug administration programs may accelerate the ...

journal_title：Current opinion in infectious diseases

authors： Caffrey CR,Secor WE

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Toxoplasmosis in haematopoietic cell transplant (HCT) recipients is associated with high morbidity and mortality rates. Prophylaxis following HCT is recommended for high-risk pre-HCT toxoplasma-seropositive (pre-HCTSP) recipients. However, there is no agreement or consistency among programmes on wheth...

journal_title：Current opinion in infectious diseases

authors： Gajurel K,Dhakal R,Montoya JG

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...

journal_title：Current opinion in infectious diseases

authors： Hickman M,De Angelis D,Vickerman P,Hutchinson S,Martin NK

更新日期：2015-12-01 00:00:00

abstract：:Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P. aeruginosa leads to progressive ...

journal_title：Current opinion in infectious diseases

authors： Brennan AL,Geddes DM

更新日期：2002-04-01 00:00:00

abstract：:Tuberculosis in childhood is an important cause of mortality worldwide. The disease is difficult to diagnose and the underlying immune mechanisms are poorly understood. Advances in the application of molecular genetic tools, as illustrated by the recent completion of the genome sequence of Mycobacterium tuberculosis, ...

journal_title：Current opinion in infectious diseases

authors： Kampmann B,Young D

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide...

journal_title：Current opinion in infectious diseases

authors： Tacke D,Koehler P,Cornely OA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen is considered a potential biological threat agent. This review focuses ...

journal_title：Current opinion in infectious diseases

authors： Saikh KU,Mott TM

更新日期：2017-06-01 00:00:00