Abstract:
PURPOSE OF REVIEW:Human brucellosis is a neglected, underrecognized infection of widespread geographic distribution. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. This review describes new information regarding the epidemiology of brucellosis in the developing world and advances in diagnosis and treatment. RECENT FINDINGS:The highest recorded incidence of human brucellosis occurs in the Middle East and Central Asia. Fever etiology studies demonstrate brucellosis as a cause of undifferentiated febrile illness in the developing world. Brucellosis is a rare cause of fever among returning travelers, but is more common among travelers returning from the Middle East and North Africa. Sensitive and specific rapid diagnostic tests appropriate for resource-limited settings have been validated. Randomized controlled trials demonstrate that optimal treatment for human brucellosis consists of doxycycline and an aminoglycoside. Decreasing the burden of human brucellosis requires control of animal brucellosis, but evidence to inform the design of control programs in the developing world is needed. SUMMARY:Brucellosis causes substantial morbidity in human and animal populations. While improvements in diagnostic options for resource-limited settings and stronger evidence for optimal therapy should enhance identification and treatment of human brucellosis, prevention of human disease through control in animals remains paramount.
journal_name
Curr Opin Infect Disjournal_title
Current opinion in infectious diseasesauthors
Rubach MP,Halliday JE,Cleaveland S,Crump JAdoi
10.1097/QCO.0b013e3283638104subject
Has Abstractpub_date
2013-10-01 00:00:00pages
404-12issue
5eissn
0951-7375issn
1473-6527journal_volume
26pub_type
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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abstract:PURPOSE OF REVIEW:Genital Chlamydia trachomatis is common among young, sexually active people. Infections are most often asymptomatic but have potential long-term consequences for female reproductive health. The link between C. trachomatis and ectopic pregnancy is mainly based on early seroepidemiological case-control ...
journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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doi:10.1097/QCO.0b013e32833ed694
更新日期:2010-12-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e32835ebcb7
更新日期:2013-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Breast surgery is considered a clean surgical procedure; nevertheless, infection rates are often higher than those reported after other similarly considered clean surgeries (e.g., thyroid, hernia). Acute bacterial skin and soft tissue infections, mostly surgical site infections and implant-associated ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000531
更新日期:2019-04-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:10.1097/QCO.0000000000000681
更新日期:2020-12-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000394
更新日期:2017-10-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000400
更新日期:2017-10-01 00:00:00
abstract::Although the association remains controversial, enteroviruses have been implicated in the aetiology of several chronic diseases in humans. Investigations in vitro lead to better understanding of virus-cell interactions, and improve our knowledge of the molecular factors that are involved in the establishment and maint...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/00001432-200106000-00002
更新日期:2001-06-01 00:00:00
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journal_title:Current opinion in infectious diseases
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doi:10.1097/QCO.0b013e3282f40689
更新日期:2008-02-01 00:00:00
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
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更新日期:2020-12-01 00:00:00
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journal_title:Current opinion in infectious diseases
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更新日期:2019-08-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2006-04-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2002-04-01 00:00:00