Prolonged infusion of beta-lactam antibiotics for Gram-negative infections: rationale and evidence base.

abstract：PURPOSE OF REVIEW:Fungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide...

journal_title：Current opinion in infectious diseases

authors： Tacke D,Koehler P,Cornely OA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Amphotericin B (AmpB) is considered the first-line treatment for visceral leishmaniasis in areas in which resistance to antimony is prevalent. This review describes recent advances in clinically available and novel drug delivery systems of AmpB to treat visceral leishmaniasis. RECENT FINDINGS:Over th...

journal_title：Current opinion in infectious diseases

authors： Mohamed-Ahmed AH,Brocchini S,Croft SL

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The recent sequencing of the whole genome of Malassezia globosa and M. restricta forms the basis for molecular epidemiology studies and instigates investigations into their respective virulence factors. Thus, reviewing current knowledge on Malassezia molecular typing methods would reveal the pros and ...

journal_title：Current opinion in infectious diseases

authors： Gaitanis G,Bassukas ID,Velegraki A

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Genital herpes has a high global prevalence and burden of disease. This manuscript highlights recent advances in our understanding of genital herpes simplex virus (HSV) infections. RECENT FINDINGS:Studies demonstrate a changing epidemiological landscape with an increasing proportion of genital herpes...

journal_title：Current opinion in infectious diseases

authors： Hofstetter AM,Rosenthal SL,Stanberry LR

更新日期：2014-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The source, significance and optimal management of low-level viraemia during highly active antiretroviral therapy (HAART) are poorly defined. This review highlights recent observations that have implications for clinical practice. RECENT FINDINGS:The definition of low-level viraemia remains elusive. ...

journal_title：Current opinion in infectious diseases

authors： Doyle T,Geretti AM

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The emergence of 2009 pandemic H1N1 influenza A (pH1N1) has provided a unique challenge to influenza control in healthcare settings. We provide an overview of the early lessons from the 2009 pandemic. RECENT FINDINGS:The modes of influenza transmission and their contributions to the development of in...

journal_title：Current opinion in infectious diseases

authors： Carlson AL,Budd AP,Perl TM

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the potential new diagnostic tools for determining the cause of pneumonia in the setting of community-acquired infection after outlining the limitation of currently available tests. RECENT FINDINGS:A number of new tools are on the horizon with the potential to overcome the problems of exist...

journal_title：Current opinion in infectious diseases

authors： Basnayake TL,Waterer GW

更新日期：2015-04-01 00:00:00

abstract：:The best way to control chlamydial diseases is with an effective vaccine. Although previous studies suggest that a vaccine is an achievable goal, progress has been limited even though many vaccination strategies have been tested. A clearer understanding of the immunobiological basis of chlamydial protection and pathol...

journal_title：Current opinion in infectious diseases

authors： Yang X,Brunham RC

更新日期：1999-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Cytomegalovirus infection is initiated when tumor necrosis factor binds to the cytomegalovirus receptors of latently infected cells, resulting in the reactivation of the virus and the production of clinical disease of two types: direct infection causing pneumonia, mononucleosis, colitis and other vira...

journal_title：Current opinion in infectious diseases

authors： Rubin RH

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on some of the recent advances in the understanding of HIV immunopathogenesis and the diagnosis and treatment of several autoimmune conditions associated with HIV in the era of potent antiretroviral therapy. RECENT FINDINGS:Chronic immune activation with progressive immune exhaust...

journal_title：Current opinion in infectious diseases

authors： Stratton R,Slapak G,Mahungu T,Kinloch-de Loes S

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Vaccination in pregnancy boosts maternal vaccine-specific antibody concentration and therefore increases transplacental transfer of antibody to optimize protection of the infant. The purpose of this review is to describe what is known about placental transfer of antibody in the context of vaccination ...

journal_title：Current opinion in infectious diseases

authors： Calvert A,Jones CE

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to assess the recent studies of therapy of pregnant women and neonates, aimed at preventing the consequences of congenital cytomegalovirus (CMV) infection. RECENT FINDINGS:A recent randomized controlled trial of treatment of CMV during pregnancy with hyperimmune globulin...

journal_title：Current opinion in infectious diseases

authors： Rawlinson WD,Hamilton ST,van Zuylen WJ

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Migrants living in high-income countries are disproportionately affected by HIV infection and frequently have characteristics associated with poor HIV clinical outcomes. HIV epidemiology among migrants is influenced by changes in migration patterns and variations in transmission risk behaviors. Here w...

journal_title：Current opinion in infectious diseases

authors： Ross J,Cunningham CO,Hanna DB

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to evaluate basic mechanisms, prevalence, risk factors, outcomes, and potential treatments of cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP). RECENT FINDINGS:In this review, we present a new model to evaluate the pathophysiology of cardiac disease in patie...

journal_title：Current opinion in infectious diseases

authors： Aliberti S,Ramirez JA

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The issue of whether the outcome of bacteremic pneumococcal infections is improved with the use of combination antibiotic therapy versus monotherapy is still not resolved. This review highlights recent studies that have addressed this issue. RECENT FINDINGS:Some studies have indicated benefit of comb...

journal_title：Current opinion in infectious diseases

authors： Feldman C,Anderson R

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The leishmaniases, caused by protozoan parasites of the genus Leishmania, are a significant health problem in many regions of the world. This review highlights the recent advances in the study of leishmaniasis related to parasite biology, disease pathogenesis, clinical evaluation and treatment, and pr...

journal_title：Current opinion in infectious diseases

authors： Melby PC

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The detection of latent tuberculosis infection (LTBI) in different categories of compromised patients is reviewed with focus on the role of strategies incorporating immunodiagnostic tests and analysis of epidemiological and clinical risk factors. RECENT FINDINGS:The development of active tuberculosis...

journal_title：Current opinion in infectious diseases

authors： Sauzullo I,Vullo V,Mastroianni CM

更新日期：2015-06-01 00:00:00

abstract：:The implementation of surveillance systems for HIV and of large cohort studies have allowed for the construction of models that more accurately describe the HIV epidemic. This review focuses on changes in the epidemiological pattern, and the effect of changes in behaviour and of antiretroviral therapy. ...

journal_title：Current opinion in infectious diseases

authors： Greco D

更新日期：1998-02-01 00:00:00

abstract：:The past few years have seen important developments in understanding the epidemiological and virological characteristics of rotaviruses, and rapid progress has been made in rotavirus vaccine development, but further challenges remain before a vaccine is introduced into widespread use. The licensure of the first rotavi...

journal_title：Current opinion in infectious diseases

authors： Lynch M,Bresee JS,Gentsch JR,Glass RI

更新日期：2000-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Skin and soft tissue infections (SSTIs) in patients with hematological malignancies are frequent, but dedicated epidemiological studies are limited. The aim of this review is to provide updated description of the main etiological agents, differential diagnosis, and treatment. RECENT FINDINGS:In addit...

journal_title：Current opinion in infectious diseases

authors： Ungaro R,Mikulska M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV infection profoundly impairs the immune mechanisms needed to control and clear Leishmania infection, and outcomes in patients with HIV-associated visceral leishmaniasis are poor. This review summarizes recent work describing the epidemiology, presentation and outcomes of HIV-associated visceral le...

journal_title：Current opinion in infectious diseases

authors： Jarvis JN,Lockwood DN

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To explore recent developments in computerized evidence-based guidelines and decision support systems that have been designed to improve the effectiveness and efficiency of antibiotic prescribing. RECENT FINDINGS:The most frequently utilized decision support systems are electronic guidelines and prot...

journal_title：Current opinion in infectious diseases

authors： Sintchenko V,Coiera E,Gilbert GL

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator-associated pneumonia (VAP) is the most frequent cause of death among the nosocomial infections acquired in the ICU. Routine surveillance endotracheal aspirate (ETA) cultures in patients on mechanical ventilation have been proposed to predict the cause of VAP. Our aim is to review the availa...

journal_title：Current opinion in infectious diseases

authors： Luna CM,Bledel I,Raimondi A

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacillus Calmette-Guerin (BCG) vaccination has been performed since 1921, and remains the best method of preventing severe infections caused by Mycobacterium tuberculosis. Tuberculosis, in its various forms, remains a public health problem, and more than 100 countries continue BCG vaccination in an ef...

journal_title：Current opinion in infectious diseases

authors： Bellet JS,Prose NS

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Associations between processes of care for hospitalized community-acquired pneumonia patients and clinical outcomes are important because of the high incidence of such admissions and substantial related mortality. Several studies have examined these associations. RECENT FINDINGS:Large retrospective s...

journal_title：Current opinion in infectious diseases

authors： Houck PM,Bratzler DW

更新日期：2005-04-01 00:00:00

abstract：:Therapeutic approaches in the practice of haematology/oncology are increasing in complexity. Agents such as the purine analogues and monoclonal antibodies may introduce a new spectrum of infection as a consequence of prolonged/profound lymphoid suppression. The use of high dose therapy with stem cells support is incre...

journal_title：Current opinion in infectious diseases

authors： Potter M

更新日期：1999-08-01 00:00:00

abstract：:Tuberculosis in childhood is an important cause of mortality worldwide. The disease is difficult to diagnose and the underlying immune mechanisms are poorly understood. Advances in the application of molecular genetic tools, as illustrated by the recent completion of the genome sequence of Mycobacterium tuberculosis, ...

journal_title：Current opinion in infectious diseases

authors： Kampmann B,Young D

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In contrast to patients at risk for hospital-acquired pneumonia or mechanically ventilated patients at risk for ventilator-associated pneumonia, healthcare-associated pneumonia is a relatively new clinical entity that includes a spectrum of adult patients who have close association with acute care hos...

journal_title：Current opinion in infectious diseases

authors： Craven DE

更新日期：2006-04-01 00:00:00

abstract：:Influenza continues to be a major health concern and there is always the threat of a pandemic due to the emergence of a viral strain new to the human population, as exemplified by the avian influenza A/H5N1 virus which was responsible for six deaths in Hong Kong last year. Data reported in the past year, based on in-v...

journal_title：Current opinion in infectious diseases

authors： Mendel DB,Roberts NA

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The immune reconstitution inflammatory syndrome (IRIS) is an important clinical complication in HIV-infected patients initiating antiretroviral therapy. This review focuses on the latest literature pertaining to the pathogenesis of IRIS. RECENT FINDINGS:The clinical manifestations of IRIS are heterog...

journal_title：Current opinion in infectious diseases

authors： Martin-Blondel G,Mars LT,Liblau RS

更新日期：2012-06-01 00:00:00