The skin and soft tissue infections in hematological patients.

abstract：PURPOSE OF REVIEW:The scale-up of direct-acting antiviral (DAA) therapy and introduction of preexposure prophylaxis (PrEP) has changed the epidemiology of sexually acquired hepatitis C virus (HCV) amongst HIV-positive and HIV-negative MSM. RECENT FINDINGS:Sexually acquired HCV continues to occur predominantly amongst ...

journal_title：Current opinion in infectious diseases

authors： Lockart I,Matthews GV,Danta M

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Benzathine Penicillin G has been used to treat syphilis for over 50 years; however, the precise regimen of penicillin for treatment of syphilis in HIV-positive individuals remains a hot topic of debate. Although international guidelines recommend the same treatment for syphilis, regardless of HIV stat...

journal_title：Current opinion in infectious diseases

authors： Lawrence D,Cresswell F,Whetham J,Fisher M

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Clostridioides difficile infection (CDI) is a significant burden on the health system, especially due to high recurrence rates. Since the beginning of the CDI epidemic in early 2000s, many strategies for combatting recurrence have been explored, with moderate success so far. This review will focus on ...

journal_title：Current opinion in infectious diseases

authors： Shin JH,Warren CA

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...

journal_title：Current opinion in infectious diseases

authors： Hickman M,De Angelis D,Vickerman P,Hutchinson S,Martin NK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials. RECENT FINDINGS:At least three polyclonal and eight monoclonal antibody products have been tested in clinical tr...

journal_title：Current opinion in infectious diseases

authors： Beigel JH

更新日期：2018-12-01 00:00:00

abstract：:Urinary tract infection is the second commonest infection encountered in both the community and the hospital setting. In order to avoid complications and to minimize the unnecessary use of antibiotics, it is essential to have a useful and rapid screening test to identify urinary tract infection. The presence of nitrit...

journal_title：Current opinion in infectious diseases

authors： Smyth EG,O'Connell N

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance among Gram-negative microorganisms has alarmingly increased in the past 10 years worldwide. Infections caused by these microorganisms are difficult to treat, especially in critically ill patients.The present review examines how to accurately predict which patients carry a grea...

journal_title：Current opinion in infectious diseases

authors： Burillo A,Muñoz P,Bouza E

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Parasites and other infections have many effects on the gastrointestinal tract of individuals who are immunocompromised. Few reviews focus on parasitic infections, which are covered here. RECENT FINDINGS:The review first examines recent advances in our understanding of the taxonomy, diagnosis and tre...

journal_title：Current opinion in infectious diseases

authors： Lewthwaite P,Gill GV,Hart CA,Beeching NJ

更新日期：2005-10-01 00:00:00

abstract：:Gram-positive cocci account for the large majority of cases of infective endocarditis. Pathogenesis investigations of endocarditis have therefore focused on purported virulence factors in staphylococci, viridans group streptococci and enterococci. In addition to novel molecular techniques that have been adapted for us...

journal_title：Current opinion in infectious diseases

authors： Baddour LM

更新日期：1999-06-01 00:00:00

abstract：:Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infections in children and adults. Although the organism is felt to be the most frequent 'atypical' pathogen responsible for community-acquired pneumonia in adults, the prevalence of M. pneumoniae varies greatly from study to study, depending ...

journal_title：Current opinion in infectious diseases

authors： Hammerschlag MR

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the currently available evidence about the use oritavancin and dalbavancin for the treatment of acute bacterial skin and skin structure infections (ABSSSI) and for other potential indications. RECENT FINDINGS:In this review, we briefly summarize the available data on efficacy (from randomi...

journal_title：Current opinion in infectious diseases

authors： Bassetti M,Labate L,Vena A,Giacobbe DR

更新日期：2021-01-05 00:00:00

abstract：PURPOSE OF REVIEW:West Nile virus emerged recently in North America as a serious human and animal pathogen. This review summarizes the use of experimental infections with West Nile virus in diverse vertebrate species that have been used to answer fundamental questions about the host response, pathogenesis of West Nile ...

journal_title：Current opinion in infectious diseases

authors： Bowen RA,Nemeth NM

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV infection profoundly impairs the immune mechanisms needed to control and clear Leishmania infection, and outcomes in patients with HIV-associated visceral leishmaniasis are poor. This review summarizes recent work describing the epidemiology, presentation and outcomes of HIV-associated visceral le...

journal_title：Current opinion in infectious diseases

authors： Jarvis JN,Lockwood DN

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Early treatment of invasive mold infections improves the outcome. Therapy is often delayed, however, because available diagnostic tools such as culture, microscopy and conventional radiology lack sensitivity; consequently, empirical initiation of antifungal therapy has been advocated, particularly for...

journal_title：Current opinion in infectious diseases

authors： Maertens J,Deeren D,Dierickx D,Theunissen K

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literature on the use of machine learning for studying bacterial AMR. RECENT FI...

journal_title：Current opinion in infectious diseases

authors： Macesic N,Polubriaginof F,Tatonetti NP

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal outbreaks have been reported in healthcare settings, showing that construction activities are a serious threat to immunocompromised hosts. Preventive measures to control fungal outbreaks (especially Aspergillus spp.) are considered essential during hospital construction. In this article, we upd...

journal_title：Current opinion in infectious diseases

authors： Alvarez-Moreno CA,Combariza JF

更新日期：2019-08-01 00:00:00

abstract：:Efforts to reduce hospitalization or the length of stay are common topics in papers published last year. Chlamydia pneumoniae is now recognized worldwide as a common pathogen in community-acquired pneumonia. A great variation in the frequency of various pathogens is found in different countries, stressing the importan...

journal_title：Current opinion in infectious diseases

authors： Holmberg H

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Schistosomiasis is a chronic and morbid disease that affects hundreds of millions of the poorest individuals in (sub)tropical regions, particularly sub-Saharan Africa. Just one drug, praziquantel (PZQ), is available. As discussed, efforts to expand mass drug administration programs may accelerate the ...

journal_title：Current opinion in infectious diseases

authors： Caffrey CR,Secor WE

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The leishmaniases, caused by protozoan parasites of the genus Leishmania, are a significant health problem in many regions of the world. This review highlights the recent advances in the study of leishmaniasis related to parasite biology, disease pathogenesis, clinical evaluation and treatment, and pr...

journal_title：Current opinion in infectious diseases

authors： Melby PC

更新日期：2002-10-01 00:00:00

abstract：:The past few years have seen important developments in understanding the epidemiological and virological characteristics of rotaviruses, and rapid progress has been made in rotavirus vaccine development, but further challenges remain before a vaccine is introduced into widespread use. The licensure of the first rotavi...

journal_title：Current opinion in infectious diseases

authors： Lynch M,Bresee JS,Gentsch JR,Glass RI

更新日期：2000-10-01 00:00:00

abstract：:One of the initial responses of an organism to infection by pathogenic viruses is the synthesis of antiviral cytokines such as the type I interferons (interferon-alpha/beta), interleukins, and other proinflammatory cytokines and chemokines. Interferons provide a first line of defence against virus infections by genera...

journal_title：Current opinion in infectious diseases

authors： Grandvaux N,tenOever BR,Servant MJ,Hiscott J

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Dengue is one of the most rapidly spreading vector-borne diseases in the world, with the incidence increasing 30-fold in the past 50 years. There are currently no licensed treatments or vaccines for dengue. This review covers the recent advances in our understanding of dengue pathogenesis, including h...

journal_title：Current opinion in infectious diseases

authors： Yacoub S,Mongkolsapaya J,Screaton G

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Clostridium difficile infection and Clostridium difficile-associated diarrhea (CDAD) are growing worldwide health threats. Recent studies have identified new host risk factors, diagnostic approaches and therapies of CDAD. The present review focuses on scientific papers published in the past 18 months ...

journal_title：Current opinion in infectious diseases

authors： DuPont HL,Garey K,Caeiro JP,Jiang ZD

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal infections are prevalent in very low birthweight (<1500 g) infants and are associated with significant morbidity and mortality. A better understanding of the adherence factors, molecular diagnostics and risk factors for invasive fungal infection are important in treatment and prevention. RECEN...

journal_title：Current opinion in infectious diseases

authors： Kaufman D

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance o...

journal_title：Current opinion in infectious diseases

authors： Sood G,Parrish N

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Streptococcus pneumoniae is a major cause of morbidity and mortality in the pediatric population. The development of increasing resistance to multiple classes of antibiotics is making treatment of infections due to this organism much more difficult. The ultimate impact of high-level antibiotic resista...

journal_title：Current opinion in infectious diseases

authors： Tan TQ

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance towards conventional antibiotics is a serious problem for modern medicine and for our society. Multidrug-resistant bacteria are very difficult to treat and treatment options have begun to run out. Here, we summarize the newest studies of drug development using cationic antimic...

journal_title：Current opinion in infectious diseases

authors： Ashby M,Petkova A,Hilpert K

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence of the protective effect of voluntary medical male circumcision (VMMC) against HIV is well established. However, evidence of the protective effect of VMMC against other sexually transmitted infections (STIs) has been inconsistent or scarce across different populations and settings. This revie...

journal_title：Current opinion in infectious diseases

authors： Matoga M,Hosseinipour MC,Jewett S,Hoffman IF,Chasela C

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent literature on Chagas disease in the immunosuppressed host. RECENT FINDINGS:Chagas disease in immunosuppressed patients may represent acute transmission in an organ recipient, or reactivation of chronic infection in an HIV-infected individual or patient receiving cardiac tr...

journal_title：Current opinion in infectious diseases

authors： Bern C

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review available data on carbapenem use in ICU. Carbapenem is a broad spectrum well tolerated antibiotic family that keep an excellent activity to extended spectrum β-lactamases and AmpC hyperproducer and in susceptible Pseudomonas aeruginosa and Acinetobacter baumannii. It becomes a drug of choice...

journal_title：Current opinion in infectious diseases

authors： Patrier J,Timsit JF

更新日期：2020-02-01 00:00:00