Cationic antimicrobial peptides as potential new therapeutic agents in neonates and children: a review.

abstract：PURPOSE OF REVIEW:Preventive chemotherapy is advocated for the global control and elimination of schistosomiasis. Despite the well known short-term benefits of treating patients for schistosomiasis, the impact of mass drug administration (MDA) campaigns to control the disease in the long term remains unresolved. RECEN...

journal_title：Current opinion in infectious diseases

authors： Olveda DU,McManus DP,Ross AG

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal infections are prevalent in very low birthweight (<1500 g) infants and are associated with significant morbidity and mortality. A better understanding of the adherence factors, molecular diagnostics and risk factors for invasive fungal infection are important in treatment and prevention. RECEN...

journal_title：Current opinion in infectious diseases

authors： Kaufman D

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Hepatitis E, a disease transmitted by hepatitis E virus, is increasingly recognized as being indigenous to affluent, temperate-zone countries. Issues pertaining to disease acquisition and hepatitis E virus infection, particularly in Western countries, are reviewed and highlighted. RECENT FINDINGS:Cli...

journal_title：Current opinion in infectious diseases

authors： Teo CG

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To consider new treatment options for cytomegalovirus (CMV) infection, review recent trials, and anticipate their use in clinical practice, focussing on bone marrow transplantation, congenital infection, and intervention during pregnancy. RECENT FINDINGS:Three double-blind randomized placebo-controll...

journal_title：Current opinion in infectious diseases

authors： Griffiths P,Lumley S

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS:An upsurge in wild poliovirus type 1 cases in Pa...

journal_title：Current opinion in infectious diseases

authors： Bandyopadhyay AS,Macklin GR

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review identifies trends in the study of interactions between Staphylococcus aureus and humans. When nasal colonization is in the neutral state, infection clearly represents a state of host-pathogen disbalance. The features leading from apparent homeostatic colonization to pathogenesis are identi...

journal_title：Current opinion in infectious diseases

authors： van Belkum A

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progress in the management of pulmonary infections in the hematopoietic cell transplant (HCT) population, substantial diagnostic, and therapeutic uncertainty remains. RECENT FINDINGS:A growing HCT population reflects more transplants and improved long-term survival. We continue to learn about...

journal_title：Current opinion in infectious diseases

authors： Ford ES,Crothers K,Cheng GS

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacterial meningitis is a medical emergency and is associated with a high disease burden. We reviewed recent progress in the management of patients with community-acquired bacterial meningitis. RECENT FINDINGS:The worldwide burden of disease of bacterial meningitis remains high, despite the decreasin...

journal_title：Current opinion in infectious diseases

authors： Costerus JM,Brouwer MC,Bijlsma MW,van de Beek D

更新日期：2017-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Early treatment of invasive mold infections improves the outcome. Therapy is often delayed, however, because available diagnostic tools such as culture, microscopy and conventional radiology lack sensitivity; consequently, empirical initiation of antifungal therapy has been advocated, particularly for...

journal_title：Current opinion in infectious diseases

authors： Maertens J,Deeren D,Dierickx D,Theunissen K

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize important papers concerning measles disease and measles-containing vaccines published in 2004. RECENT FINDINGS:Endemic measles has been successfully controlled in the Americas and, to a lesser extent, in Europe. This has been achieved with a high uptake of t...

journal_title：Current opinion in infectious diseases

authors： Elliman D,Sengupta N

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Infectious keratitis is a medical emergency. Improper management can lead to marked loss of vision. This review identifies recent trends in the study of infectious keratitis. RECENT FINDINGS:A multicountry outbreak of Fusarium keratitis emphasizes that contact lens wear is a major risk factor for inf...

journal_title：Current opinion in infectious diseases

authors： Thomas PA,Geraldine P

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review available data on carbapenem use in ICU. Carbapenem is a broad spectrum well tolerated antibiotic family that keep an excellent activity to extended spectrum β-lactamases and AmpC hyperproducer and in susceptible Pseudomonas aeruginosa and Acinetobacter baumannii. It becomes a drug of choice...

journal_title：Current opinion in infectious diseases

authors： Patrier J,Timsit JF

更新日期：2020-02-01 00:00:00

abstract：:Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infections in children and adults. Although the organism is felt to be the most frequent 'atypical' pathogen responsible for community-acquired pneumonia in adults, the prevalence of M. pneumoniae varies greatly from study to study, depending ...

journal_title：Current opinion in infectious diseases

authors： Hammerschlag MR

更新日期：2001-04-01 00:00:00

abstract：:Although HIV-associated lipodystrophy can be diagnosed just from clinical examination, criteria for diagnosis and judgement of severity are not clearly defined. Clinical assessment can be systematized with questionnaires for patients and physicians. Computed tomography, nuclear magnetic imaging and dual-energy X-ray a...

journal_title：Current opinion in infectious diseases

authors： Schwenk A

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Enteric fever continues to be an important infection among populations in endemic countries and among travelers to these areas. This review aims to describe recent epidemiological trends and developments in diagnosis, treatment and prevention. RECENT FINDINGS:Data indicate that the burden of enteric ...

journal_title：Current opinion in infectious diseases

authors： Meltzer E,Schwartz E

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To explore how ethical considerations, improved diagnostics and data from clinical trials might see the lowering of some of the barriers blocking a cure for HIV infection over the next 5 years. RECENT FINDINGS:Despite the recent well publicized but eventually disappointing case reports, there remains...

journal_title：Current opinion in infectious diseases

authors： Thornhill J,Fidler S,Frater J

更新日期：2015-02-01 00:00:00

abstract：:Lyme disease is the most common vector-borne infection affecting children living in temperate parts of the western hemisphere. The widespread anxiety about the long-term consequences of the illness, however, finds no support in the literature. Although the number of long-term follow-up studies is limited, the prognosi...

journal_title：Current opinion in infectious diseases

authors： Berglund J

更新日期：1999-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Hepatitis C virus is an RNA virus that usually establishes persistent infection in its host. As an important cause of cirrhosis and hepatocellular carcinoma worldwide, hepatitis C is a growing public health concern. Despite recent advances in therapy, most people infected with the virus can expect lif...

journal_title：Current opinion in infectious diseases

authors： Darling JM,Wright TL

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal outbreaks have been reported in healthcare settings, showing that construction activities are a serious threat to immunocompromised hosts. Preventive measures to control fungal outbreaks (especially Aspergillus spp.) are considered essential during hospital construction. In this article, we upd...

journal_title：Current opinion in infectious diseases

authors： Alvarez-Moreno CA,Combariza JF

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the current success of artemisinin combination therapy, the threat of drug-resistant falciparum malaria remains severe. Reversal of resistance to old drugs remains one strategy to deal with this problem. This review highlights recent significant findings. RECENT FINDINGS:This review provides ...

journal_title：Current opinion in infectious diseases

authors： Egan TJ,Kaschula CH

更新日期：2007-12-01 00:00:00

abstract：:Intestinal protozoal infections cause significant disease not only in the tropics but also in immunocompromised hosts and returning travellers in the developed world. Precise diagnosis of protozoal intestinal infection by microscopy can be difficult. Enzyme immunoassays for antigen detection are being used for some pr...

journal_title：Current opinion in infectious diseases

authors： Schuster H,Chiodini PL

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a history of inadequate treatments for cryptosporidiosis and a lack of understanding of the species that cause human disease. Against this background, we review the efficacy of antiparasitic agents, particularly nitazoxanide, which has led to increased treatment options, the potential for imm...

journal_title：Current opinion in infectious diseases

authors： Smith HV,Corcoran GD

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The success of male circumcision in reducing HIV acquisition among African heterosexuals has led to renewed interest in this biological intervention for HIV/sexually transmissible infection (STI) prevention in men who have sex with men (MSM). This review summarizes the available data on the associatio...

journal_title：Current opinion in infectious diseases

authors： Templeton DJ,Millett GA,Grulich AE

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to summarize recent developments in our understanding of the modifiable behavioural and biological factors contributing to the transmission of genital herpes simplex infection, and the limited data on the use of antiviral agents for reducing transmission risk in serodiscordan...

journal_title：Current opinion in infectious diseases

authors： Patel R

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Evidence of the protective effect of voluntary medical male circumcision (VMMC) against HIV is well established. However, evidence of the protective effect of VMMC against other sexually transmitted infections (STIs) has been inconsistent or scarce across different populations and settings. This revie...

journal_title：Current opinion in infectious diseases

authors： Matoga M,Hosseinipour MC,Jewett S,Hoffman IF,Chasela C

更新日期：2021-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Dengue, the most common arbovirus, is an increasingly significant cause of morbidity worldwide. After decades of research, an approved tetravalent dengue vaccine is finally available. Models constructed using recently available vaccine efficacy data allow for a data-driven discussion of the potential ...

journal_title：Current opinion in infectious diseases

authors： Robinson ML,Durbin AP

更新日期：2017-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Dolutegravir (DTG) is a second-generation integrase strand transfer inhibitor (InSTI) with an outstanding antiviral potency, good tolerability, good pharmacokinetic profile with a lack of major drug-drug interactions, and a barrier to resistance higher than the other compounds of the class (raltegravi...

journal_title：Current opinion in infectious diseases

authors： Blanco JL,Marcelin AG,Katlama C,Martinez E

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review describes the literature about the prevention of Staphylococcus aureus infections in surgery, published from August 2006 to January 2008, and puts it into perspective. RECENT FINDINGS:To prevent Staphylococcus aureus infections after surgical procedures, three methods were describe...

journal_title：Current opinion in infectious diseases

authors： van Rijen MM,Kluytmans JA

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV postexposure prophylaxis is often recommended following potential sexual exposure to HIV. Recent data address the effectiveness of postexposure prophylaxis and prevention counseling, cost-effectiveness, antiretroviral options, challenges with nonoccupational postexposure prophylaxis among adolesce...

journal_title：Current opinion in infectious diseases

authors： Roland ME

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Integrase strand transfer inhibitors (INSTIs) have become a key component of antiretroviral therapy since the approval of twice-daily raltegravir in 2007 and the more recent approval of elvitegravir in 2012. At the same time, a third compound, dolutegravir, is in late-phase clinical trials, being test...

journal_title：Current opinion in infectious diseases

authors： Quashie PK,Mesplède T,Wainberg MA

更新日期：2013-02-01 00:00:00