Abstract:
PURPOSE OF REVIEW:Enteric fever continues to be an important infection among populations in endemic countries and among travelers to these areas. This review aims to describe recent epidemiological trends and developments in diagnosis, treatment and prevention. RECENT FINDINGS:Data indicate that the burden of enteric fever is declining in many middle-income countries, whereas the bulk of cases occur in the Indian subcontinent and in south-east Asia. In these regions, Salmonella Paratyphi A is increasingly seen and sometimes surpasses Salmonella Typhi as the main pathogen. Enteric fever caused by S. Paratyphi A is indistinguishable from that caused by S. Typhi. In addition, drug resistance, including nalidixic acid/quinolone resistance now occurs in the majority of clinical isolates of S. Typhi and S. Paratyphi A in Asia. Currently, third generation cephalosporins and azythromycin are the only reasonable therapeutic options for most cases of travel-related enteric fever. SUMMARY:The ongoing emergence of S. Paratyphi A results in partial benefit from current typhoid vaccines in the prevention of enteric fever in travelers. Increasing antimicrobial resistance complicates therapy for travel-related enteric fever. New vaccines, offering protection against both agents of enteric fever, are urgently needed; however, none of the current vaccine candidates is likely to be available for several years.
journal_name
Curr Opin Infect Disjournal_title
Current opinion in infectious diseasesauthors
Meltzer E,Schwartz Edoi
10.1097/QCO.0b013e32833c7ca1subject
Has Abstractpub_date
2010-10-01 00:00:00pages
432-7issue
5eissn
0951-7375issn
1473-6527journal_volume
23pub_type
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000400
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abstract:PURPOSE OF REVIEW:Parasites and other infections have many effects on the gastrointestinal tract of individuals who are immunocompromised. Few reviews focus on parasitic infections, which are covered here. RECENT FINDINGS:The review first examines recent advances in our understanding of the taxonomy, diagnosis and tre...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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abstract::Gram-positive cocci account for the large majority of cases of infective endocarditis. Pathogenesis investigations of endocarditis have therefore focused on purported virulence factors in staphylococci, viridans group streptococci and enterococci. In addition to novel molecular techniques that have been adapted for us...
journal_title:Current opinion in infectious diseases
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000559
更新日期:2019-08-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/qco.0b013e3283118932
更新日期:2008-12-01 00:00:00
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更新日期:2020-06-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2015-02-01 00:00:00
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更新日期:2017-08-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000372
更新日期:2017-06-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3283567b7e
更新日期:2012-10-01 00:00:00
abstract:PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000216
更新日期:2015-12-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3282f4f237
更新日期:2008-04-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e328359eff2
更新日期:2012-12-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3283232a30
更新日期:2009-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/QCO.0000000000000654
更新日期:2020-08-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2018-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2014-02-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2005-04-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Current opinion in infectious diseases
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更新日期:2017-08-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2012-10-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2010-08-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2019-02-01 00:00:00