Effects of HIV voluntary medical male circumcision programs on sexually transmitted infections.

abstract：PURPOSE OF REVIEW:The aim of the article is to present recent epidemiological, microbiological, and clinical data for the surgical, antimicrobial, and adjunctive management of necrotizing soft-tissue infections (NSTI). RECENT FINDINGS:NSTI can be caused by a broad variety of organisms. Reports about NSTI caused by mul...

journal_title：Current opinion in infectious diseases

authors： Eckmann C,Montravers P

更新日期：2020-12-04 00:00:00

abstract：PURPOSE OF REVIEW:The detection of latent tuberculosis infection (LTBI) in different categories of compromised patients is reviewed with focus on the role of strategies incorporating immunodiagnostic tests and analysis of epidemiological and clinical risk factors. RECENT FINDINGS:The development of active tuberculosis...

journal_title：Current opinion in infectious diseases

authors： Sauzullo I,Vullo V,Mastroianni CM

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:As physicians are confronted with a diversity of adverse events and variability in response to medication among patients, this review will focus on the available evidence regarding the impact of genetic variation on drug response. Specifically, variation in drug metabolizing enzymes such as the cytoch...

journal_title：Current opinion in infectious diseases

authors： Boffito M,Winston A,Owen A

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Associations between processes of care for hospitalized community-acquired pneumonia patients and clinical outcomes are important because of the high incidence of such admissions and substantial related mortality. Several studies have examined these associations. RECENT FINDINGS:Large retrospective s...

journal_title：Current opinion in infectious diseases

authors： Houck PM,Bratzler DW

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic pulmonary aspergillosis (CPA) is a relatively rare, slowly progressive pulmonary syndrome due to Aspergillus spp. that requires specific knowledge in terms of disease entity, diagnosis, management and azole resistance. This review focuses on the recent understanding of CPA entity and the emerg...

journal_title：Current opinion in infectious diseases

authors： Izumikawa K,Takazono T,Kohno S

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent studies suggest that contemporary antibiotic dosing is unlikely to achieve best outcomes for critically ill patients because of extensive pharmacokinetic variability and altered pharmacodynamics. Dose adaptation is considered quite challenging because of unpredictable dose-exposure relationship...

journal_title：Current opinion in infectious diseases

authors： Parker SL,Sime FB,Roberts JA

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although available therapies can effectively inhibit hepatitis B virus (HBV) replication in patients with active chronic hepatitis B (CHB) infection, therapeutic efficacy is limited because of potential drug resistance, and an inability to mediate viral clearance and to rectify immune impairment in CH...

journal_title：Current opinion in infectious diseases

authors： Pan J,Tong S,Kang L,Tang J

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...

journal_title：Current opinion in infectious diseases

authors： Hickman M,De Angelis D,Vickerman P,Hutchinson S,Martin NK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite diagnostic and therapeutic advances, acute haematogenous osteomyelitis in children continues to cause significant morbidity and disease burden. The molecular epidemiology of causal organisms has wide geographic variation, but regardless of cause children often require several weeks of inpatien...

journal_title：Current opinion in infectious diseases

authors： Weichert S,Sharland M,Clarke NM,Faust SN

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent literature on Chagas disease in the immunosuppressed host. RECENT FINDINGS:Chagas disease in immunosuppressed patients may represent acute transmission in an organ recipient, or reactivation of chronic infection in an HIV-infected individual or patient receiving cardiac tr...

journal_title：Current opinion in infectious diseases

authors： Bern C

更新日期：2012-08-01 00:00:00

abstract：:Otitis media is a very common reason for the prescription of antibiotics in children. Antimicrobial therapy is mostly empirical, based on the knowledge of the frequency and susceptibility patterns of causative pathogens and of the penetration and other pharmacokinetic properties of several oral antibiotics. Pharmacoec...

journal_title：Current opinion in infectious diseases

authors： Paradisi F,Corti G

更新日期：1998-12-01 00:00:00

abstract：:Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infections in children and adults. Although the organism is felt to be the most frequent 'atypical' pathogen responsible for community-acquired pneumonia in adults, the prevalence of M. pneumoniae varies greatly from study to study, depending ...

journal_title：Current opinion in infectious diseases

authors： Hammerschlag MR

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Amphotericin B (AmpB) is considered the first-line treatment for visceral leishmaniasis in areas in which resistance to antimony is prevalent. This review describes recent advances in clinically available and novel drug delivery systems of AmpB to treat visceral leishmaniasis. RECENT FINDINGS:Over th...

journal_title：Current opinion in infectious diseases

authors： Mohamed-Ahmed AH,Brocchini S,Croft SL

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Opportunistic infections contribute to morbidity and mortality after myeloablative allogeneic stem cell transplantation. The development of nonmyeloablative or toxicity-reduced conditioning regimens for allogeneic hematopoietic stem cell transplantation might change this picture significantly. These r...

journal_title：Current opinion in infectious diseases

authors： Junghanss C,Marr KA

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide an update on the public health impact of food-related illness in light of recent high-profile outbreaks and advances in the methodology to estimate illness burden. It includes mainly literature from high-income countries, as burden of illness estimations have b...

journal_title：Current opinion in infectious diseases

authors： O'Brien SJ

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Rates of carbapenem-resistant Enterobacteriaceae (CRE), especially Klebsiella pneumoniae carbapenemase (KPC)-producing Gram-negatives, have increased worldwide. Infections caused by these organisms have been associated with a high mortality, which might be due in part to the limited availability of an...

journal_title：Current opinion in infectious diseases

authors： Munoz-Price LS,Quinn JP

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Necrotizing enterocolitis remains an enigmatic and potentially devastating condition with high morbidity and mortality. This review explores ways in which bacterial pathogens, together with gut microflora, influence the pathophysiology of necrotizing enterocolitis. Specifically, it examines the role o...

journal_title：Current opinion in infectious diseases

authors： Hammerman C,Kaplan M

更新日期：2006-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Breast surgery is considered a clean surgical procedure; nevertheless, infection rates are often higher than those reported after other similarly considered clean surgeries (e.g., thyroid, hernia). Acute bacterial skin and soft tissue infections, mostly surgical site infections and implant-associated ...

journal_title：Current opinion in infectious diseases

authors： Corcione S,Lupia T,De Rosa FG

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Cryptococcal meningitis causes significant mortality among HIV-infected patients, despite antifungal therapy and use of antiretroviral therapy (ART). In patients with cryptococcal meningitis, ART is often complicated by immune reconstitution inflammatory syndrome (IRIS), manifesting as unmasking of pr...

journal_title：Current opinion in infectious diseases

authors： Meya DB,Manabe YC,Boulware DR,Janoff EN

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Bacillus Calmette-Guerin (BCG) vaccination has been performed since 1921, and remains the best method of preventing severe infections caused by Mycobacterium tuberculosis. Tuberculosis, in its various forms, remains a public health problem, and more than 100 countries continue BCG vaccination in an ef...

journal_title：Current opinion in infectious diseases

authors： Bellet JS,Prose NS

更新日期：2005-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The immune reconstitution inflammatory syndrome (IRIS) is an important clinical complication in HIV-infected patients initiating antiretroviral therapy. This review focuses on the latest literature pertaining to the pathogenesis of IRIS. RECENT FINDINGS:The clinical manifestations of IRIS are heterog...

journal_title：Current opinion in infectious diseases

authors： Martin-Blondel G,Mars LT,Liblau RS

更新日期：2012-06-01 00:00:00

abstract：:Helicobacter pylori is a bacterium that colonizes the human stomach, especially during childhood. Although it has been studied intensively during the past decade, many controversies still exist on many important issues, including the clinical relevance of virulence factors, indications for treatment, recommended proce...

journal_title：Current opinion in infectious diseases

authors： Vandenplas Y

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progress in the management of pulmonary infections in the hematopoietic cell transplant (HCT) population, substantial diagnostic, and therapeutic uncertainty remains. RECENT FINDINGS:A growing HCT population reflects more transplants and improved long-term survival. We continue to learn about...

journal_title：Current opinion in infectious diseases

authors： Ford ES,Crothers K,Cheng GS

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Human brucellosis is a neglected, underrecognized infection of widespread geographic distribution. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. This review describes new information regarding t...

journal_title：Current opinion in infectious diseases

authors： Rubach MP,Halliday JE,Cleaveland S,Crump JA

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Toxoplasmosis in haematopoietic cell transplant (HCT) recipients is associated with high morbidity and mortality rates. Prophylaxis following HCT is recommended for high-risk pre-HCT toxoplasma-seropositive (pre-HCTSP) recipients. However, there is no agreement or consistency among programmes on wheth...

journal_title：Current opinion in infectious diseases

authors： Gajurel K,Dhakal R,Montoya JG

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides the rationale for the development of new antibiotics to treat community-acquired pneumonia (CAP). It also provides an overview of the new antibiotics targeting CAP that have recently received approval by the regulatory agencies, and those antibiotics that are in the development pi...

journal_title：Current opinion in infectious diseases

authors： Kollef MH,Betthauser KD

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:New respiratory viruses have been discovered in recent years and new molecular diagnostic assays have been developed that improve our understanding of respiratory virus infections. This article will review the changing epidemiology of these viruses after hematopoietic stem cell and solid organ transpl...

journal_title：Current opinion in infectious diseases

authors： Renaud C,Campbell AP

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The early treatment of invasive fungal infection is critical but is hampered by the non-specific nature of clinical and radiological signs and the insensitivity of current laboratory diagnostic methods. If mortality due to invasive fungal infection is to be reduced, new, preemptive therapeutic strateg...

journal_title：Current opinion in infectious diseases

authors： Jones BL,McLintock LA

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Dolutegravir (DTG) is a second-generation integrase strand transfer inhibitor (InSTI) with an outstanding antiviral potency, good tolerability, good pharmacokinetic profile with a lack of major drug-drug interactions, and a barrier to resistance higher than the other compounds of the class (raltegravi...

journal_title：Current opinion in infectious diseases

authors： Blanco JL,Marcelin AG,Katlama C,Martinez E

更新日期：2018-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The success of male circumcision in reducing HIV acquisition among African heterosexuals has led to renewed interest in this biological intervention for HIV/sexually transmissible infection (STI) prevention in men who have sex with men (MSM). This review summarizes the available data on the associatio...

journal_title：Current opinion in infectious diseases

authors： Templeton DJ,Millett GA,Grulich AE

更新日期：2010-02-01 00:00:00