Infective endocarditis: new concepts in pathogenesis.

abstract：:This review reports on recent developments in the areas of diagnosis, chemotherapy and pathology, where female genital schistosomiasis was recently identified as a common cause of morbidity in Schistosoma haematobium-endemic areas. As a profound understanding of processes underlying resistance and susceptibility to in...

journal_title：Current opinion in infectious diseases

authors： Yazdanbakhsh M,Deelder AM

更新日期：1998-10-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Viruses are an increasingly recognized cause of community-acquired pneumonia (CAP), but their exact role in nosocomial pneumonia is still debated. This review focuses on the role of viruses as a cause of nosocomial pneumonia. RECENT FINDINGS:Respiratory viruses may be responsible for healthcare-a...

journal_title：Current opinion in infectious diseases

authors： Luyt CE,Bréchot N,Chastre J

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Several attempts have been made to combine drugs for treating visceral leishmaniasis, but only recently have effective drugs become available and combinations been tested systematically. RECENT FINDINGS:Sequential treatments with liposomal amphotericin B followed by miltefosine or paromomycin (as sho...

journal_title：Current opinion in infectious diseases

authors： Olliaro PL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights progress made in the development of vaccines aimed at the stages of malaria parasites found in mosquitoes that block the transmission of malaria within a community. RECENT FINDINGS:Substantial progress has been made on the production and characterization of the leading candidat...

journal_title：Current opinion in infectious diseases

authors： Saul A

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The source, significance and optimal management of low-level viraemia during highly active antiretroviral therapy (HAART) are poorly defined. This review highlights recent observations that have implications for clinical practice. RECENT FINDINGS:The definition of low-level viraemia remains elusive. ...

journal_title：Current opinion in infectious diseases

authors： Doyle T,Geretti AM

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal infections are prevalent in very low birthweight (<1500 g) infants and are associated with significant morbidity and mortality. A better understanding of the adherence factors, molecular diagnostics and risk factors for invasive fungal infection are important in treatment and prevention. RECEN...

journal_title：Current opinion in infectious diseases

authors： Kaufman D

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:With increasing recognition of the importance of sexual networks in the dissemination of sexually transmitted infections (STIs), research is expanding. This review focuses on methodology for conducting sexual network research with in-depth presentations of recent and novel studies conducted on four co...

journal_title：Current opinion in infectious diseases

authors： Doherty IA

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Climate change, deforestation, urbanization, and increased population mobility have made the risk of large outbreaks of yellow fever more likely than ever. Yellow fever vaccine production barely meets demands. In this review, we address the causes of the recent yellow fever outbreaks, why fractional d...

journal_title：Current opinion in infectious diseases

authors： Visser LG

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Benzathine Penicillin G has been used to treat syphilis for over 50 years; however, the precise regimen of penicillin for treatment of syphilis in HIV-positive individuals remains a hot topic of debate. Although international guidelines recommend the same treatment for syphilis, regardless of HIV stat...

journal_title：Current opinion in infectious diseases

authors： Lawrence D,Cresswell F,Whetham J,Fisher M

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide...

journal_title：Current opinion in infectious diseases

authors： Tacke D,Koehler P,Cornely OA

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV postexposure prophylaxis is often recommended following potential sexual exposure to HIV. Recent data address the effectiveness of postexposure prophylaxis and prevention counseling, cost-effectiveness, antiretroviral options, challenges with nonoccupational postexposure prophylaxis among adolesce...

journal_title：Current opinion in infectious diseases

authors： Roland ME

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Cryptococcal meningitis causes significant mortality among HIV-infected patients, despite antifungal therapy and use of antiretroviral therapy (ART). In patients with cryptococcal meningitis, ART is often complicated by immune reconstitution inflammatory syndrome (IRIS), manifesting as unmasking of pr...

journal_title：Current opinion in infectious diseases

authors： Meya DB,Manabe YC,Boulware DR,Janoff EN

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:West Nile virus emerged recently in North America as a serious human and animal pathogen. This review summarizes the use of experimental infections with West Nile virus in diverse vertebrate species that have been used to answer fundamental questions about the host response, pathogenesis of West Nile ...

journal_title：Current opinion in infectious diseases

authors： Bowen RA,Nemeth NM

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progress in the management of pulmonary infections in the hematopoietic cell transplant (HCT) population, substantial diagnostic, and therapeutic uncertainty remains. RECENT FINDINGS:A growing HCT population reflects more transplants and improved long-term survival. We continue to learn about...

journal_title：Current opinion in infectious diseases

authors： Ford ES,Crothers K,Cheng GS

更新日期：2020-04-01 00:00:00

abstract：:Although HIV-associated lipodystrophy can be diagnosed just from clinical examination, criteria for diagnosis and judgement of severity are not clearly defined. Clinical assessment can be systematized with questionnaires for patients and physicians. Computed tomography, nuclear magnetic imaging and dual-energy X-ray a...

journal_title：Current opinion in infectious diseases

authors： Schwenk A

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:As physicians are confronted with a diversity of adverse events and variability in response to medication among patients, this review will focus on the available evidence regarding the impact of genetic variation on drug response. Specifically, variation in drug metabolizing enzymes such as the cytoch...

journal_title：Current opinion in infectious diseases

authors： Boffito M,Winston A,Owen A

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:It is now well established that cytokines play a critical role in the regulation of the immune system. Processes such as lymphoid development, differentiation, homeostasis, tolerance and memory are all regulated by cytokines that bind the type I family of cytokine receptors. Like the interferons, whic...

journal_title：Current opinion in infectious diseases

authors： Gadina M,Ferguson PR,Johnston JA

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Strict adherence to clinical practice guidelines is recognized to improve outcomes but the inconvenient truth is that only a small subset of what is done in medicine has been tested in appropriate, well designed studies. In this article, we aim to review controversial aspects of the clinical managemen...

journal_title：Current opinion in infectious diseases

authors： Peçanha-Pietrobom PM,Colombo AL

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Colonization of the host epithelia by pathogenic Escherichia coli is influenced by the ability of the bacteria to interact with host surfaces. Because the initial step of an E. coli infection is to adhere, invade, and persist within host cells, some strategies used by intestinal and extraintestinal E....

journal_title：Current opinion in infectious diseases

authors： Kalita A,Hu J,Torres AG

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize important papers concerning measles disease and measles-containing vaccines published in 2004. RECENT FINDINGS:Endemic measles has been successfully controlled in the Americas and, to a lesser extent, in Europe. This has been achieved with a high uptake of t...

journal_title：Current opinion in infectious diseases

authors： Elliman D,Sengupta N

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to discuss the rationale of and current evidence for prolonged beta-lactam infusion in the management of Gram-negative infections. RECENT FINDINGS:Pharmacokinetic/pharmacodynamic (PK/PD) data from various in-vitro and in-vivo experimental studies conclusively support prolong...

journal_title：Current opinion in infectious diseases

authors： Abdul-Aziz MH,Portunato F,Roberts JA

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In hematopoietic cell transplant (HCT) recipients, paramyxovirus infections are major viral respiratory tract infections that, if they progress to lower respiratory tract infections, are associated with reduced survival rates in this population. There are important knowledge gaps regarding treatment d...

journal_title：Current opinion in infectious diseases

authors： Batista MV,El Haddad L,Chemaly RF

更新日期：2018-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review identifies trends in the study of interactions between Staphylococcus aureus and humans. When nasal colonization is in the neutral state, infection clearly represents a state of host-pathogen disbalance. The features leading from apparent homeostatic colonization to pathogenesis are identi...

journal_title：Current opinion in infectious diseases

authors： van Belkum A

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Japanese encephalitis is the most common vaccine-preventable viral encephalitis in Asia. In view of the production cessation of the inactivated mouse brain-derived Japanese encephalitis vaccine, it is timely to provide an update on new Japanese encephalitis vaccines and revised vaccine recommendations...

journal_title：Current opinion in infectious diseases

authors： Wilder-Smith A,Halstead SB

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review risk-based pre-emptive treatment for adenovirus (ADV) based on quantitative PCR (qPCR) and to provide an update on clinical trials of brincidofovir (BCV) and ADV-specific cytotoxic T lymphocytes (ADV-CTLs). RECENT FINDINGS:ADV qPCR in various body compartments enables distinction of clinica...

journal_title：Current opinion in infectious diseases

authors： Lee YJ,Prockop SE,Papanicolaou GA

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:As the evidence for two-drug regimens (2DR) for HIV treatment accumulates and 2DR start to enter consensus guidelines, this review covers the history, rationale and current evidence for 2DR in first-line and switch settings. RECENT FINDINGS:Until recently, most evidence for 2DR was for boosted protea...

journal_title：Current opinion in infectious diseases

authors： Waters L,Church H

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of the article is to present recent epidemiological, microbiological, and clinical data for the surgical, antimicrobial, and adjunctive management of necrotizing soft-tissue infections (NSTI). RECENT FINDINGS:NSTI can be caused by a broad variety of organisms. Reports about NSTI caused by mul...

journal_title：Current opinion in infectious diseases

authors： Eckmann C,Montravers P

更新日期：2020-12-04 00:00:00

abstract：PURPOSE OF REVIEW:Chronic pulmonary aspergillosis (CPA) is a relatively rare, slowly progressive pulmonary syndrome due to Aspergillus spp. that requires specific knowledge in terms of disease entity, diagnosis, management and azole resistance. This review focuses on the recent understanding of CPA entity and the emerg...

journal_title：Current opinion in infectious diseases

authors： Izumikawa K,Takazono T,Kohno S

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Two recent large randomized placebo-controlled clinical trials of adjunctive inhaled therapy for the treatment of ventilator-associated pneumonia failed to show a mortality effect or more rapid resolution of pneumonia symptoms. Does the failure of these studies to reach their endpoints suggest the end...

journal_title：Current opinion in infectious diseases

authors： Palmer LB

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to provide an update of nonantibiotic therapies for acute gastroenteritis (AGE), focusing on antiemetics and probiotics. RECENT FINDINGS:The mainstay of therapy for nonsevere AGE remains oral rehydration therapy (ORT). Recent randomized controlled trials and metaanalyses hav...

journal_title：Current opinion in infectious diseases

authors： Funk A,Schnadower D,Freedman SB

更新日期：2020-10-01 00:00:00