Complicated urinary tract infection.

abstract：PURPOSE OF REVIEW:The aim of this article is to review recent publications relevant to understanding the interaction of urinary tract infection and diabetes mellitus, including epidemiology, pathogenesis, microbiology, and treatment. RECENT FINDINGS:The largest number of identified reports described aspects of epidemi...

journal_title：Current opinion in infectious diseases

authors： Nicolle LE

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:It is now well established that cytokines play a critical role in the regulation of the immune system. Processes such as lymphoid development, differentiation, homeostasis, tolerance and memory are all regulated by cytokines that bind the type I family of cytokine receptors. Like the interferons, whic...

journal_title：Current opinion in infectious diseases

authors： Gadina M,Ferguson PR,Johnston JA

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Hepatitis E, a disease transmitted by hepatitis E virus, is increasingly recognized as being indigenous to affluent, temperate-zone countries. Issues pertaining to disease acquisition and hepatitis E virus infection, particularly in Western countries, are reviewed and highlighted. RECENT FINDINGS:Cli...

journal_title：Current opinion in infectious diseases

authors： Teo CG

更新日期：2006-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Clostridioides difficile infection (CDI) is a significant burden on the health system, especially due to high recurrence rates. Since the beginning of the CDI epidemic in early 2000s, many strategies for combatting recurrence have been explored, with moderate success so far. This review will focus on ...

journal_title：Current opinion in infectious diseases

authors： Shin JH,Warren CA

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The review examines the changing causes and the investigation of infectious and noninfectious diarrhoea in individuals with HIV. RECENT FINDINGS:Despite the excellent prognosis conferred by combination antiretroviral therapy, diarrhoea is still common in HIV-positive individuals and is associated wit...

journal_title：Current opinion in infectious diseases

authors： Logan C,Beadsworth MB,Beeching NJ

更新日期：2016-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Colonization of the host epithelia by pathogenic Escherichia coli is influenced by the ability of the bacteria to interact with host surfaces. Because the initial step of an E. coli infection is to adhere, invade, and persist within host cells, some strategies used by intestinal and extraintestinal E....

journal_title：Current opinion in infectious diseases

authors： Kalita A,Hu J,Torres AG

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Pneumocystis pneumonia (PCP) is a frequent opportunistic infection associated with a high mortality rate. PCP is of increasing importance in non-HIV immunocompromised patients, who present with severe respiratory distress with low fungal loads. Molecular detection of Pneumocystis in broncho-alveolar l...

journal_title：Current opinion in infectious diseases

authors： Guegan H,Robert-Gangneux F

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Several attempts have been made to combine drugs for treating visceral leishmaniasis, but only recently have effective drugs become available and combinations been tested systematically. RECENT FINDINGS:Sequential treatments with liposomal amphotericin B followed by miltefosine or paromomycin (as sho...

journal_title：Current opinion in infectious diseases

authors： Olliaro PL

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:With the overwhelming success of combination antiretroviral therapy, HIV infection is now a chronic, but manageable, medical condition. Consequently, HIV-infected cohorts are ageing leading to new challenges in the life-long management of this condition. Here, we review recent data concerning the mode...

journal_title：Current opinion in infectious diseases

authors： Winston A,Underwood J

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Amphotericin B (AmpB) is considered the first-line treatment for visceral leishmaniasis in areas in which resistance to antimony is prevalent. This review describes recent advances in clinically available and novel drug delivery systems of AmpB to treat visceral leishmaniasis. RECENT FINDINGS:Over th...

journal_title：Current opinion in infectious diseases

authors： Mohamed-Ahmed AH,Brocchini S,Croft SL

更新日期：2012-12-01 00:00:00

abstract：:Despite the widespread prophylactic use of antifungal agents in neutropenic patients, invasive fungal infections continue to emerge as major causes of morbidity and mortality. With the exception of fluconazole prophylaxis in allogeneic marrow transplant recipients, no firm conclusions can be drawn due to the lack of r...

journal_title：Current opinion in infectious diseases

authors： Maertens JA,Boogaerts MA

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Hidradenitis suppurativa is a chronic or relapsing inflammatory cutaneous disorder manifested by recurrent formation of abscesses, fistulating sinus and scarring in the apocrine-gland-bearing skin. This review discusses the different aetiological theories and management opportunities. RECENT FINDINGS...

journal_title：Current opinion in infectious diseases

authors： Yazdanyar S,Jemec GB

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literature on the use of machine learning for studying bacterial AMR. RECENT FI...

journal_title：Current opinion in infectious diseases

authors： Macesic N,Polubriaginof F,Tatonetti NP

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents an update on the molecular epidemic patterns of HIV-1 infection and the effects of subtype-related genetic variability on transmission, disease progression, response to antiretroviral therapy and drug-resistance pathways. RECENT FINDINGS:The molecular epidemiology of HIV-1 infect...

journal_title：Current opinion in infectious diseases

authors： Geretti AM

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute gastroenteritis is one of the leading causes of morbidity and mortality in children in the developing world. With improvements in hygiene and sanitation, the burden of disease due to bacterial and parasitic infections has decreased and an increasing proportion of diarrhoea hospitalizations are a...

journal_title：Current opinion in infectious diseases

authors： Ramani S,Kang G

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite diagnostic and therapeutic advances, acute haematogenous osteomyelitis in children continues to cause significant morbidity and disease burden. The molecular epidemiology of causal organisms has wide geographic variation, but regardless of cause children often require several weeks of inpatien...

journal_title：Current opinion in infectious diseases

authors： Weichert S,Sharland M,Clarke NM,Faust SN

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide...

journal_title：Current opinion in infectious diseases

authors： Tacke D,Koehler P,Cornely OA

更新日期：2013-12-01 00:00:00

abstract：:The sequence of the Treponema pallidum genome was completed in July 1998, yielding a wealth of new information regarding the enigmatic spirochete that causes syphilis and related treponematoses. By providing the sequences and predicted functions of over 1000 genes, the genome sequence will greatly facilitate research ...

journal_title：Current opinion in infectious diseases

authors： Norris SJ,Weinstock GM

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The source, significance and optimal management of low-level viraemia during highly active antiretroviral therapy (HAART) are poorly defined. This review highlights recent observations that have implications for clinical practice. RECENT FINDINGS:The definition of low-level viraemia remains elusive. ...

journal_title：Current opinion in infectious diseases

authors： Doyle T,Geretti AM

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:An increasing number of laboratories have implemented multiplex molecular panels for the diagnosis of gastrointestinal infections. This review focuses on recent data addressing the performance of US Food and Drug Administration-cleared multiplex gastrointestinal panels and discusses the advantages and...

journal_title：Current opinion in infectious diseases

authors： Liesman RM,Binnicker MJ

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review describes the literature about the prevention of Staphylococcus aureus infections in surgery, published from August 2006 to January 2008, and puts it into perspective. RECENT FINDINGS:To prevent Staphylococcus aureus infections after surgical procedures, three methods were describe...

journal_title：Current opinion in infectious diseases

authors： van Rijen MM,Kluytmans JA

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on the recent developments in the epidemiology, burden of disease, diagnostic tests, and treatment of fascioliasis. RECENT FINDINGS:Recent epidemiologic data suggest that either the endemic areas are expanding or disease is being recognized in areas where it was not previously obs...

journal_title：Current opinion in infectious diseases

authors： Cabada MM,White AC Jr

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on some of the recent advances in the understanding of HIV immunopathogenesis and the diagnosis and treatment of several autoimmune conditions associated with HIV in the era of potent antiretroviral therapy. RECENT FINDINGS:Chronic immune activation with progressive immune exhaust...

journal_title：Current opinion in infectious diseases

authors： Stratton R,Slapak G,Mahungu T,Kinloch-de Loes S

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Enteric fever continues to be an important infection among populations in endemic countries and among travelers to these areas. This review aims to describe recent epidemiological trends and developments in diagnosis, treatment and prevention. RECENT FINDINGS:Data indicate that the burden of enteric ...

journal_title：Current opinion in infectious diseases

authors： Meltzer E,Schwartz E

更新日期：2010-10-01 00:00:00

abstract：:Interleukin-10 is the most potent anti-inflammatory cytokine yet identified. It has multiple actions affecting the innate immune system as well as humoral and cellular immune responses. It occupies a pivotal role in the regulation of the immune response to microbial pathogens in health and disease. Knowledge gained in...

journal_title：Current opinion in infectious diseases

authors： Opal SM,Huber CE

更新日期：2000-06-01 00:00:00

abstract：:Tuberculosis in childhood is an important cause of mortality worldwide. The disease is difficult to diagnose and the underlying immune mechanisms are poorly understood. Advances in the application of molecular genetic tools, as illustrated by the recent completion of the genome sequence of Mycobacterium tuberculosis, ...

journal_title：Current opinion in infectious diseases

authors： Kampmann B,Young D

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to discuss the rationale of and current evidence for prolonged beta-lactam infusion in the management of Gram-negative infections. RECENT FINDINGS:Pharmacokinetic/pharmacodynamic (PK/PD) data from various in-vitro and in-vivo experimental studies conclusively support prolong...

journal_title：Current opinion in infectious diseases

authors： Abdul-Aziz MH,Portunato F,Roberts JA

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We review the potential new diagnostic tools for determining the cause of pneumonia in the setting of community-acquired infection after outlining the limitation of currently available tests. RECENT FINDINGS:A number of new tools are on the horizon with the potential to overcome the problems of exist...

journal_title：Current opinion in infectious diseases

authors： Basnayake TL,Waterer GW

更新日期：2015-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Vaccination in pregnancy boosts maternal vaccine-specific antibody concentration and therefore increases transplacental transfer of antibody to optimize protection of the infant. The purpose of this review is to describe what is known about placental transfer of antibody in the context of vaccination ...

journal_title：Current opinion in infectious diseases

authors： Calvert A,Jones CE

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal infections are prevalent in very low birthweight (<1500 g) infants and are associated with significant morbidity and mortality. A better understanding of the adherence factors, molecular diagnostics and risk factors for invasive fungal infection are important in treatment and prevention. RECEN...

journal_title：Current opinion in infectious diseases

authors： Kaufman D

更新日期：2004-06-01 00:00:00