Abstract:
PURPOSE OF REVIEW:Bacillus Calmette-Guerin (BCG) vaccination has been performed since 1921, and remains the best method of preventing severe infections caused by Mycobacterium tuberculosis. Tuberculosis, in its various forms, remains a public health problem, and more than 100 countries continue BCG vaccination in an effort to control the disease. Since the initiation of BCG vaccination, numerous complications have been reported. In this review we will focus on the cutaneous complications of BCG vaccination. RECENT FINDINGS:Recent case reports detail the development of large keloids, and also of juvenile sarcoidosis after BCG vaccination. Adverse outcomes from inadvertent intradermal injection of the forearm and from revaccination with BCG have also been reported. Other recently described skin complications subsequent to BCG vaccination include lupus vulgaris, delayed granuloma formation, cutaneous BCG infection in immune disorders, anterior chest wall mass, acute erythroderma with multiple skin abscesses, ulceration at the BCG site during Kawasaki disease, fixed drug eruption, and cutaneous abscesses following mesotherapy. SUMMARY:BCG vaccination will continue to be a key method of preventing severe tuberculosis infections for the foreseeable future. The World Health Organization currently recommends BCG vaccination for all infants living in tuberculosis endemic areas. As such, it is important for health care providers to recognize the routinely anticipated cutaneous findings of the vaccination, in addition to complications relating to the injection. Subsequent care of these skin complications is of paramount importance to the health of these patients.
journal_name
Curr Opin Infect Disjournal_title
Current opinion in infectious diseasesauthors
Bellet JS,Prose NSdoi
10.1097/01.qco.0000160895.97362.4fsubject
Has Abstractpub_date
2005-04-01 00:00:00pages
97-100issue
2eissn
0951-7375issn
1473-6527pii
00001432-200504000-00003journal_volume
18pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Despite the current success of artemisinin combination therapy, the threat of drug-resistant falciparum malaria remains severe. Reversal of resistance to old drugs remains one strategy to deal with this problem. This review highlights recent significant findings. RECENT FINDINGS:This review provides ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3282f1673a
更新日期:2007-12-01 00:00:00
abstract:PURPOSE OF REVIEW:This review focuses on some of the recent advances in the understanding of HIV immunopathogenesis and the diagnosis and treatment of several autoimmune conditions associated with HIV in the era of potent antiretroviral therapy. RECENT FINDINGS:Chronic immune activation with progressive immune exhaust...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3283210006
更新日期:2009-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Migrants living in high-income countries are disproportionately affected by HIV infection and frequently have characteristics associated with poor HIV clinical outcomes. HIV epidemiology among migrants is influenced by changes in migration patterns and variations in transmission risk behaviors. Here w...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000415
更新日期:2018-02-01 00:00:00
abstract::Tuberculosis in childhood is an important cause of mortality worldwide. The disease is difficult to diagnose and the underlying immune mechanisms are poorly understood. Advances in the application of molecular genetic tools, as illustrated by the recent completion of the genome sequence of Mycobacterium tuberculosis, ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The early treatment of invasive fungal infection is critical but is hampered by the non-specific nature of clinical and radiological signs and the insensitivity of current laboratory diagnostic methods. If mortality due to invasive fungal infection is to be reduced, new, preemptive therapeutic strateg...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/00001432-200312000-00002
更新日期:2003-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Bronchiectasis is an under-appreciated cause of chronic lung disease in the USA. We highlight developments in diagnosis and treatment of this debilitating disease. RECENT FINDINGS:A possible link between gastroesophageal reflux and development of nontuberculous mycobacterial lung disease was highligh...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3282f4f237
更新日期:2008-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The emergence of 2009 pandemic H1N1 influenza A (pH1N1) has provided a unique challenge to influenza control in healthcare settings. We provide an overview of the early lessons from the 2009 pandemic. RECENT FINDINGS:The modes of influenza transmission and their contributions to the development of in...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e32833bb804
更新日期:2010-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Benzathine Penicillin G has been used to treat syphilis for over 50 years; however, the precise regimen of penicillin for treatment of syphilis in HIV-positive individuals remains a hot topic of debate. Although international guidelines recommend the same treatment for syphilis, regardless of HIV stat...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000132
更新日期:2015-02-01 00:00:00
abstract:PURPOSE OF REVIEW:This review highlights progress made in the development of vaccines aimed at the stages of malaria parasites found in mosquitoes that block the transmission of malaria within a community. RECENT FINDINGS:Substantial progress has been made on the production and characterization of the leading candidat...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3282a95e12
更新日期:2007-10-01 00:00:00
abstract:PURPOSE OF REVIEW:The present review summarizes key studies on the effects of major abdominal surgery on the host response to infection published during the last 18 months. RECENT FINDINGS:Surgical trauma causes stereotyped systemic proinflammatory and compensatory anti-inflammatory reactions. It is leukocyte reprogra...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e32833939cb
更新日期:2010-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS:An upsurge in wild poliovirus type 1 cases in Pa...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:10.1097/QCO.0000000000000667
更新日期:2020-10-01 00:00:00
abstract::Influenza continues to be a major health concern and there is always the threat of a pandemic due to the emergence of a viral strain new to the human population, as exemplified by the avian influenza A/H5N1 virus which was responsible for six deaths in Hong Kong last year. Data reported in the past year, based on in-v...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:10.1097/00001432-199812000-00013
更新日期:1998-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Fungal outbreaks have been reported in healthcare settings, showing that construction activities are a serious threat to immunocompromised hosts. Preventive measures to control fungal outbreaks (especially Aspergillus spp.) are considered essential during hospital construction. In this article, we upd...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:10.1097/QCO.0000000000000566
更新日期:2019-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Bacterial meningitis is a medical emergency and is associated with a high disease burden. We reviewed recent progress in the management of patients with community-acquired bacterial meningitis. RECENT FINDINGS:The worldwide burden of disease of bacterial meningitis remains high, despite the decreasin...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000335
更新日期:2017-02-01 00:00:00
abstract:PURPOSE OF REVIEW:This review presents an update on the molecular epidemic patterns of HIV-1 infection and the effects of subtype-related genetic variability on transmission, disease progression, response to antiretroviral therapy and drug-resistance pathways. RECENT FINDINGS:The molecular epidemiology of HIV-1 infect...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/01.qco.0000200293.45532.68
更新日期:2006-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Ventilator-associated pneumonia (VAP) is the most frequent cause of death among the nosocomial infections acquired in the ICU. Routine surveillance endotracheal aspirate (ETA) cultures in patients on mechanical ventilation have been proposed to predict the cause of VAP. Our aim is to review the availa...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000042
更新日期:2014-04-01 00:00:00
abstract::Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P. aeruginosa leads to progressive ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/00001432-200204000-00013
更新日期:2002-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Prion diseases such as Creutzfeldt-Jakob disease represent a unique infection control problem because prions exhibit an unusual resistance to conventional chemical and physical decontamination methods. This paper reviews the recent literature and provides recommendations for the prevention of nosocomi...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/00001432-200208000-00011
更新日期:2002-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Early treatment of invasive mold infections improves the outcome. Therapy is often delayed, however, because available diagnostic tools such as culture, microscopy and conventional radiology lack sensitivity; consequently, empirical initiation of antifungal therapy has been advocated, particularly for...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3280106854
更新日期:2006-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The need for better drugs to treat patients with Chagas disease remains urgent. This review summarizes the advancements in drug development over the past 2 years. RECENT FINDINGS:Drug development efforts are almost exclusively occurring as preclinical research, although phase II studies for the antif...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e3283402956
更新日期:2010-12-01 00:00:00
abstract:PURPOSE OF THE REVIEW:Viruses are an increasingly recognized cause of community-acquired pneumonia (CAP), but their exact role in nosocomial pneumonia is still debated. This review focuses on the role of viruses as a cause of nosocomial pneumonia. RECENT FINDINGS:Respiratory viruses may be responsible for healthcare-a...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000049
更新日期:2014-04-01 00:00:00
abstract::This review reports on recent developments in the areas of diagnosis, chemotherapy and pathology, where female genital schistosomiasis was recently identified as a common cause of morbidity in Schistosoma haematobium-endemic areas. As a profound understanding of processes underlying resistance and susceptibility to in...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:10.1097/00001432-199810000-00005
更新日期:1998-10-01 00:00:00
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journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2012-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Co-infection with Plasmodium falciparum malaria and Epstein-Barr virus (EBV) are implicated in the cause of endemic Burkitt lymphoma (eBL), the most prevalent pediatric cancer in equatorial Africa. Although the causal association between EBV and eBL has been established, P. falciparum malaria's role i...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e328349ac4f
更新日期:2011-10-01 00:00:00
abstract::Urinary tract infection is the second commonest infection encountered in both the community and the hospital setting. In order to avoid complications and to minimize the unnecessary use of antibiotics, it is essential to have a useful and rapid screening test to identify urinary tract infection. The presence of nitrit...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章
doi:10.1097/00001432-199802000-00014
更新日期:1998-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Clostridium difficile infection and Clostridium difficile-associated diarrhea (CDAD) are growing worldwide health threats. Recent studies have identified new host risk factors, diagnostic approaches and therapies of CDAD. The present review focuses on scientific papers published in the past 18 months ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0b013e32830f9397
更新日期:2008-10-01 00:00:00
abstract:PURPOSE OF REVIEW:The scale-up of direct-acting antiviral (DAA) therapy and introduction of preexposure prophylaxis (PrEP) has changed the epidemiology of sexually acquired hepatitis C virus (HCV) amongst HIV-positive and HIV-negative MSM. RECENT FINDINGS:Sexually acquired HCV continues to occur predominantly amongst ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2019-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Antibiotic resistance continues to rise, whereas development of new agents to counter it has slowed. A heightened need exists to maintain the effectiveness of currently available agents. This review focuses on the need for better antimicrobial stewardship, expected benefits of well designed antimicrob...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2011-02-01 00:00:00
abstract:PURPOSE OF REVIEW:To explore recent developments in computerized evidence-based guidelines and decision support systems that have been designed to improve the effectiveness and efficiency of antibiotic prescribing. RECENT FINDINGS:The most frequently utilized decision support systems are electronic guidelines and prot...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
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更新日期:2008-12-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe the epidemiology, strategies for early detection, and clinical management of infections caused by the most commonly found multidrug-resistant (MDR) Candida spp. RECENT FINDINGS:Increasing numbers of reports describing invasive infections by MDR Candida auris and Candida glabrata has been ...
journal_title:Current opinion in infectious diseases
pub_type: 杂志文章,评审
doi:10.1097/QCO.0000000000000411
更新日期:2017-12-01 00:00:00