HIV outcomes among migrants from low-income and middle-income countries living in high-income countries: a review of recent evidence.

abstract：PURPOSE OF REVIEW:As physicians are confronted with a diversity of adverse events and variability in response to medication among patients, this review will focus on the available evidence regarding the impact of genetic variation on drug response. Specifically, variation in drug metabolizing enzymes such as the cytoch...

journal_title：Current opinion in infectious diseases

authors： Boffito M,Winston A,Owen A

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the current success of artemisinin combination therapy, the threat of drug-resistant falciparum malaria remains severe. Reversal of resistance to old drugs remains one strategy to deal with this problem. This review highlights recent significant findings. RECENT FINDINGS:This review provides ...

journal_title：Current opinion in infectious diseases

authors： Egan TJ,Kaschula CH

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize important papers concerning measles disease and measles-containing vaccines published in 2004. RECENT FINDINGS:Endemic measles has been successfully controlled in the Americas and, to a lesser extent, in Europe. This has been achieved with a high uptake of t...

journal_title：Current opinion in infectious diseases

authors： Elliman D,Sengupta N

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To explore recent developments in computerized evidence-based guidelines and decision support systems that have been designed to improve the effectiveness and efficiency of antibiotic prescribing. RECENT FINDINGS:The most frequently utilized decision support systems are electronic guidelines and prot...

journal_title：Current opinion in infectious diseases

authors： Sintchenko V,Coiera E,Gilbert GL

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Healthcare-associated infections (HAIs) challenge healthcare systems worldwide. As healthcare workers' hands are considered the main vector for transmission of pathogens, effective hand hygiene is the single most important action to prevent HAIs. We sought to highlight new developments and advances in...

journal_title：Current opinion in infectious diseases

authors： Stadler RN,Tschudin-Sutter S

更新日期：2020-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To explore how ethical considerations, improved diagnostics and data from clinical trials might see the lowering of some of the barriers blocking a cure for HIV infection over the next 5 years. RECENT FINDINGS:Despite the recent well publicized but eventually disappointing case reports, there remains...

journal_title：Current opinion in infectious diseases

authors： Thornhill J,Fidler S,Frater J

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Sepsis is an inflammatory condition associated with significant morbidity and mortality. Given the lack of specific therapies for the condition, prevention has garnered significant interest and increased importance. The article reviews the current literature regarding the use of aspirin and statins fo...

journal_title：Current opinion in infectious diseases

authors： Sanchez MA,Thomas CB,O'Neal HR

更新日期：2012-06-01 00:00:00

abstract：:One of the initial responses of an organism to infection by pathogenic viruses is the synthesis of antiviral cytokines such as the type I interferons (interferon-alpha/beta), interleukins, and other proinflammatory cytokines and chemokines. Interferons provide a first line of defence against virus infections by genera...

journal_title：Current opinion in infectious diseases

authors： Grandvaux N,tenOever BR,Servant MJ,Hiscott J

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Dolutegravir (DTG) is a second-generation integrase strand transfer inhibitor (InSTI) with an outstanding antiviral potency, good tolerability, good pharmacokinetic profile with a lack of major drug-drug interactions, and a barrier to resistance higher than the other compounds of the class (raltegravi...

journal_title：Current opinion in infectious diseases

authors： Blanco JL,Marcelin AG,Katlama C,Martinez E

更新日期：2018-06-01 00:00:00

abstract：:Tuberculosis in childhood is an important cause of mortality worldwide. The disease is difficult to diagnose and the underlying immune mechanisms are poorly understood. Advances in the application of molecular genetic tools, as illustrated by the recent completion of the genome sequence of Mycobacterium tuberculosis, ...

journal_title：Current opinion in infectious diseases

authors： Kampmann B,Young D

更新日期：1998-06-01 00:00:00

abstract：PURPOSE OF REVIEW:New respiratory viruses have been discovered in recent years and new molecular diagnostic assays have been developed that improve our understanding of respiratory virus infections. This article will review the changing epidemiology of these viruses after hematopoietic stem cell and solid organ transpl...

journal_title：Current opinion in infectious diseases

authors： Renaud C,Campbell AP

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance o...

journal_title：Current opinion in infectious diseases

authors： Sood G,Parrish N

更新日期：2017-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute gastroenteritis is one of the leading causes of morbidity and mortality in children in the developing world. With improvements in hygiene and sanitation, the burden of disease due to bacterial and parasitic infections has decreased and an increasing proportion of diarrhoea hospitalizations are a...

journal_title：Current opinion in infectious diseases

authors： Ramani S,Kang G

更新日期：2009-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Giardiasis is one of the most common causes of diarrheal disease worldwide, yet existing antimicrobial therapies are not always effective and drug resistance occurs in vivo and in vitro. The review focuses on recent advances in the development of new antigiardial drug candidates. RECENT FINDINGS:Modi...

journal_title：Current opinion in infectious diseases

authors： Tejman-Yarden N,Eckmann L

更新日期：2011-10-01 00:00:00

abstract：:Intestinal protozoal infections cause significant disease not only in the tropics but also in immunocompromised hosts and returning travellers in the developed world. Precise diagnosis of protozoal intestinal infection by microscopy can be difficult. Enzyme immunoassays for antigen detection are being used for some pr...

journal_title：Current opinion in infectious diseases

authors： Schuster H,Chiodini PL

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The scale-up of direct-acting antiviral (DAA) therapy and introduction of preexposure prophylaxis (PrEP) has changed the epidemiology of sexually acquired hepatitis C virus (HCV) amongst HIV-positive and HIV-negative MSM. RECENT FINDINGS:Sexually acquired HCV continues to occur predominantly amongst ...

journal_title：Current opinion in infectious diseases

authors： Lockart I,Matthews GV,Danta M

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:18F-Fluorodeoxyglucose positron emission tomography/computed tomography is a well-established technique for diagnosis and management of a number of neoplastic conditions. However, in recent years the body of literature regarding its potential role in infectious diseases has progressively increased, wi...

journal_title：Current opinion in infectious diseases

authors： Bassetti M,Carnelutti A,Muser D,Righi E,Petrosillo N,Di Gregorio F,Werner TJ,Alavi A

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The detection of latent tuberculosis infection (LTBI) in different categories of compromised patients is reviewed with focus on the role of strategies incorporating immunodiagnostic tests and analysis of epidemiological and clinical risk factors. RECENT FINDINGS:The development of active tuberculosis...

journal_title：Current opinion in infectious diseases

authors： Sauzullo I,Vullo V,Mastroianni CM

更新日期：2015-06-01 00:00:00

abstract：:Influenza continues to be a major health concern and there is always the threat of a pandemic due to the emergence of a viral strain new to the human population, as exemplified by the avian influenza A/H5N1 virus which was responsible for six deaths in Hong Kong last year. Data reported in the past year, based on in-v...

journal_title：Current opinion in infectious diseases

authors： Mendel DB,Roberts NA

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The issue of whether the outcome of bacteremic pneumococcal infections is improved with the use of combination antibiotic therapy versus monotherapy is still not resolved. This review highlights recent studies that have addressed this issue. RECENT FINDINGS:Some studies have indicated benefit of comb...

journal_title：Current opinion in infectious diseases

authors： Feldman C,Anderson R

更新日期：2009-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Pneumocystis pneumonia (PCP) is a frequent opportunistic infection associated with a high mortality rate. PCP is of increasing importance in non-HIV immunocompromised patients, who present with severe respiratory distress with low fungal loads. Molecular detection of Pneumocystis in broncho-alveolar l...

journal_title：Current opinion in infectious diseases

authors： Guegan H,Robert-Gangneux F

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Dengue is one of the most rapidly spreading vector-borne diseases in the world, with the incidence increasing 30-fold in the past 50 years. There are currently no licensed treatments or vaccines for dengue. This review covers the recent advances in our understanding of dengue pathogenesis, including h...

journal_title：Current opinion in infectious diseases

authors： Yacoub S,Mongkolsapaya J,Screaton G

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Imiquimod is the first member of a new class of immune response modifiers; it was first approved in 1997 for the topical treatment of external genital and perianal warts. It is an imidazoquinoline, a novel synthetic compound which is an immune response stimulator, enhancing both the innate and acquire...

journal_title：Current opinion in infectious diseases

authors： Garland SM

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will focus on the epidemiology and cause of diarrheal illness in solid organ transplant and stem-cell transplant population recipients with a specific focus on the role of advanced multiplex technology in the diagnosis of diarrhea within this patient population. RECENT FINDINGS:A wide ran...

journal_title：Current opinion in infectious diseases

authors： Santoiemma PP,Ison MG,Angarone MP

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review summarizes key studies on the effects of major abdominal surgery on the host response to infection published during the last 18 months. RECENT FINDINGS:Surgical trauma causes stereotyped systemic proinflammatory and compensatory anti-inflammatory reactions. It is leukocyte reprogra...

journal_title：Current opinion in infectious diseases

authors： Buttenschoen K,Fathimani K,Buttenschoen DC

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Toxoplasmosis in haematopoietic cell transplant (HCT) recipients is associated with high morbidity and mortality rates. Prophylaxis following HCT is recommended for high-risk pre-HCT toxoplasma-seropositive (pre-HCTSP) recipients. However, there is no agreement or consistency among programmes on wheth...

journal_title：Current opinion in infectious diseases

authors： Gajurel K,Dhakal R,Montoya JG

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:With the overwhelming success of combination antiretroviral therapy, HIV infection is now a chronic, but manageable, medical condition. Consequently, HIV-infected cohorts are ageing leading to new challenges in the life-long management of this condition. Here, we review recent data concerning the mode...

journal_title：Current opinion in infectious diseases

authors： Winston A,Underwood J

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS:An upsurge in wild poliovirus type 1 cases in Pa...

journal_title：Current opinion in infectious diseases

authors： Bandyopadhyay AS,Macklin GR

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The early treatment of invasive fungal infection is critical but is hampered by the non-specific nature of clinical and radiological signs and the insensitivity of current laboratory diagnostic methods. If mortality due to invasive fungal infection is to be reduced, new, preemptive therapeutic strateg...

journal_title：Current opinion in infectious diseases

authors： Jones BL,McLintock LA

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This is a review of tafenoquine, a new antimalarial drug. Here we examine the recent literature supporting the use of tafenoquine and summarize the opportunities and challenges for its well tolerated use worldwide. RECENT FINDINGS:Tafenoquine was recently approved by the US Food and Drug Administrati...

journal_title：Current opinion in infectious diseases

authors： Chen V,Daily JP

更新日期：2019-10-01 00:00:00