Restricted response of mesencephalic neural crest to sympathetic differentiation signals in the trunk.

abstract：:The cortex and subcortical regions of the developing follicles and eggs of silkmoths are rich in cytoskeletal elements, particularly actin. In situ analysis using [3H]-polyuridylic acid and biotinylated oligo d(T) reveals a pattern of changes in poly(A)+ RNA distribution during oogenesis. The developing pattern of dis...

journal_title：Developmental biology

authors： Watson CA,Sauman I,Berry SJ

更新日期：1993-02-01 00:00:00

abstract：:Clotting is critical in limiting hemolymph loss and initiating wound healing in insects as in vertebrates. It is also an important immune defense, quickly forming a secondary barrier to infection, immobilizing bacteria and thereby promoting their killing. However, hemolymph clotting is one of the least understood immu...

journal_title：Developmental biology

authors： Scherfer C,Qazi MR,Takahashi K,Ueda R,Dushay MS,Theopold U,Lemaitre B

更新日期：2006-07-01 00:00:00

abstract：:A fundamental issue during nervous system development is how individual cells are formed from the undefined precursors. Differentiated neurons and glia, two major cell types mediating neuronal function, are acquired from immature precursors via a series of explicit controls exerted by transcription factors such as pro...

journal_title：Developmental biology

authors： Mao H,Lv Z,Ho MS

更新日期：2012-10-01 00:00:00

abstract：:Activin is a potent inducer of axial mesoderm in vitro and may have a similar role in vivo. Xenopus laevis eggs contain significant amounts of activin or activin-like factors, but maternal activin transcripts have not been detected in Xenopus eggs. The maternal activin protein might be translated from activin beta A o...

journal_title：Developmental biology

authors： Rebagliati MR,Dawid IB

更新日期：1993-10-01 00:00:00

abstract：:The kidney of the Gpc3-/ mouse, a novel model of human renal dysplasia, is characterized by selective degeneration of medullary collecting ducts preceded by enhanced cell proliferation and overgrowth during branching morphogenesis. Here, we identify cellular and molecular mechanisms underlying this renal dysplasia. Gl...

journal_title：Developmental biology

authors： Grisaru S,Cano-Gauci D,Tee J,Filmus J,Rosenblum ND

更新日期：2001-03-01 00:00:00

abstract：:Extracellular modulators of cell-cell signaling control numerous aspects of organismal development. The Twisted gastrulation (Twsg1) gene product is a small, secreted cysteine-rich protein that has the unusual property of being able to either enhance or inhibit signaling by the bone morphogenetic protein (BMP) subfami...

journal_title：Developmental biology

authors： Petryk A,Anderson RM,Jarcho MP,Leaf I,Carlson CS,Klingensmith J,Shawlot W,O'Connor MB

更新日期：2004-03-15 00:00:00

abstract：:Nonmuscle myosin-II is a key motor protein that drives cell shape change and cell movement. Here, we analyze the function of nonmuscle myosin-II during Drosophila embryonic myogenesis. We find that nonmuscle myosin-II and the adhesion molecule, PS2 integrin, colocalize at the developing muscle termini. In the paradigm...

journal_title：Developmental biology

authors： Bloor JW,Kiehart DP

更新日期：2001-11-15 00:00:00

abstract：:It has been difficult to examine the role of TGF-ß in post-natal tooth development due to perinatal lethality in many of the signaling deficient mouse models. To address the role of Tgfbr2 in postnatal tooth development, we generated a mouse in which Tgfbr2 was deleted in odontoblast- and bone-producing mesenchyme. Os...

journal_title：Developmental biology

authors： Wang Y,Cox MK,Coricor G,MacDougall M,Serra R

更新日期：2013-10-01 00:00:00

abstract：:XX gonads differentiate into ovaries, a morphologic event evident by embryonic day 13.5 (E13.5) in mice. To identify early markers of oogenesis, sex-specific urogenital ridge cDNA libraries were constructed from E12-13 embryos. After mass excision and isolation of plasmid DNA, approximately 4800 expressed sequence tag...

journal_title：Developmental biology

authors： Takasaki N,McIsaac R,Dean J

更新日期：2000-07-01 00:00:00

abstract：:Previous studies suggest that sensory innervation of muscles is patterned by motor innervation. Muscle afferent projections mirror motor projections after various experimental manipulations and muscle afferents fail to project to muscle in the absence of motoneurons. It is not known, however, whether muscle afferents ...

journal_title：Developmental biology

authors： Wang G,Scott SA

更新日期：1997-06-01 00:00:00

abstract：:We have isolated Xbr-1, a novel Xenopus homeobox gene that defines a new class of homeobox genes, distantly related to the Drosophila BarH1 and BarH2 genes. Xbr-1 is predominantly expressed in the developing Xenopus eye, starting as early as the neural plate stage. At early stages of eye development XBR-1 is expressed...

journal_title：Developmental biology

authors： Papalopulu N,Kintner C

更新日期：1996-02-25 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygotes of Fucus and Pelvetia. Here, it is shown that blue light (but not red light) increased cyclic GMP levels of Pelvetia zygotes by about a factor of 2. When the increase in cyclic GMP was blocked by a guanylyl cyclase inhibitor, photopolariz...

journal_title：Developmental biology

authors： Robinson KR,Miller BJ

更新日期：1997-07-01 00:00:00

abstract：:Serotonin is a classical small-molecule neurotransmitter with known effects on developmental processes. Previous studies have shown a developmental role for serotonin in the fly peripheral nervous system. In this study, we show that serotonin can modulate the development of serotonergic varicosities within the fly cen...

journal_title：Developmental biology

authors： Sykes PA,Condron BG

更新日期：2005-10-01 00:00:00

abstract：:The distribution and ontogeny of four neuropeptides in developing chick lumbosacral sensory and sympathetic ganglia were studied using immunohistochemical techniques. Antibodies to two of these peptides, substance P (SP) and calcitonin gene-related peptide (CGRP), stained small neurons in the medial part of the dorsal...

journal_title：Developmental biology

authors： New HV,Mudge AW

更新日期：1986-08-01 00:00:00

abstract：:Myoblasts of the L6 rat cell line were grown in Ham's F12 nutrient medium containing 10% fetal calf serum (F12 + FCS). Although the cells were confluent by 6 days in culture, fusion was not observed even if cultures were maintained for 10-14 days. At least 80% of the cells in such confluent unfused cultures were in th...

journal_title：Developmental biology

authors： Pinset C,Whalen RG

更新日期：1984-04-01 00:00:00

abstract：:Anuran amphibian embryos (Xenopus laevis and Rana dybowskii) are sensitive to novel gravitational fields. Under simulated weightlessness, (i) the location of the first horizontal cleavage furrow was shifted toward the vegetal pole at the eight-cell stage; (ii) the position of the blastocoel was more centered, and the ...

journal_title：Developmental biology

authors： Neff AW,Yokota H,Chung HM,Wakahara M,Malacinski GM

更新日期：1993-01-01 00:00:00

abstract：:Primitive blood constitutes the ventralmost mesoderm in amphibians, and its cleavage-stage origin reveals important clues about the orientation of the dorsal/ventral axis in the embryo. In recent years, investigators employing various lineage-labeling strategies have reported disparate results for the origin of primit...

journal_title：Developmental biology

authors： Lane MC,Sheets MD

更新日期：2002-08-01 00:00:00

abstract：:The distribution of the catalytic and regulatory subunits of the cAMP-dependent protein kinase between cytoplasm and nucleus was determined during the development of Dictyostelium discoideum. In vegetative amoebae approximately 2% of the subunits were in the nucleus. During development there was an approximately 5-fol...

journal_title：Developmental biology

authors： Woffendin C,Chambers TC,Schaller KL,Leichtling BH,Rickenberg HV

更新日期：1986-05-01 00:00:00

abstract：:To investigate the molecular regulation of embryonic somite formation and development, we have cloned the full-length cDNA and characterized the embryonic expression profile of chicken Paraxis, a member of a novel family of basic helix-loop-helix (bHLH) proteins, which has been suggested to play a role in paraxial mes...

journal_title：Developmental biology

authors： Barnes GL,Alexander PG,Hsu CW,Mariani BD,Tuan RS

更新日期：1997-09-01 00:00:00

abstract：:Planarians are well-known for their exceptional regenerative abilities. This investigation focuses on the involvement of a Y-box protein, defined by the presence of a cold-shock domain, in regeneration-specific processes. Previous studies have shown that developmentally expressed Y-box proteins bind to mRNA molecules ...

journal_title：Developmental biology

authors： Salvetti A,Batistoni R,Deri P,Rossi L,Sommerville J

更新日期：1998-09-15 00:00:00

abstract：:Eggs of the newt, Cynops pyrrhogaster, arrested at the second meiotic metaphase are activated by sperm at fertilization and then complete meiosis to initiate development. We highly purified a sperm factor for egg activation from a sperm extract with several chromatographies. The purified fraction containing only a 45 ...

journal_title：Developmental biology

authors： Harada Y,Matsumoto T,Hirahara S,Nakashima A,Ueno S,Oda S,Miyazaki S,Iwao Y

更新日期：2007-06-15 00:00:00

abstract：:Hox genes are crucial players in the generation and pattering of the vertebrate trunk and posterior body during embryogenesis. Their initial expression takes place shortly after the establishment of the primitive streak, in the posterior-most part of the mouse embryo and is a determinant step for setting up the defini...

journal_title：Developmental biology

authors： Neijts R,Deschamps J

更新日期：2017-08-15 00:00:00

abstract：:Cell proliferation, growth and survival are three different basic processes which converge at determining a fundamental property -the size of an organism. Scalloped (Sd) is the first characterised transcriptional partner to Yorkie (Yki), the downstream effector of the Hippo pathway which is a highly potential and evol...

journal_title：Developmental biology

authors： Rohith BN,Shyamala BV

更新日期：2017-12-15 00:00:00

abstract：:The tadpole-type larva of Ciona has emerged as an intriguing model system for the study of neurodevelopment. The Ciona intestinalis connectome has been recently mapped, revealing the smallest central nervous system (CNS) known in any chordate, with only 177 neurons. This minimal CNS is highly reminiscent of larger CNS...

journal_title：Developmental biology

authors： Sharma S,Wang W,Stolfi A

更新日期：2019-04-15 00:00:00

abstract：:Zygotic gene activation is essential for development beyond the 2-cell stage in the preimplantation mouse embryo. Based on alpha-amanitin-sensitive BrUTP incorporation, transcription initiates in the 1-cell embryo and a major reprogramming of gene expression driven by newly expressed genes is prominently observed duri...

journal_title：Developmental biology

authors： Zeng F,Schultz RM

更新日期：2005-07-01 00:00:00

abstract：:Eye cups from stage 14-28 (E2 to E5) chick and quail embryos consisting of neural retina, lens, and vitreous body were cultured for 1 or 2 days. These eyes expanded by proliferation of the retinal cells and the surface areas of the retinae increased several-fold. The area covered by ganglion cells and axons also expan...

journal_title：Developmental biology

authors： Halfter W,Deiss S

更新日期：1986-04-01 00:00:00

abstract：:Oocyte maturation (meiosis reinitiation) in starfish is induced by the natural hormone 1-methyladenine (1-MeAde). Oocytes of Evasterias troschelii contain 0.43 pmole cyclic AMP/mg protein and 0.47 pmole cyclic GMP/mg protein. Upon stimulation by 1-MeAde the oocytes undergo a moderate (10-30%) decrease in their cAMP co...

journal_title：Developmental biology

authors： Meijer L,Zarutskie P

更新日期：1987-06-01 00:00:00

abstract：:The GATA family of transcription factors are known to play multiple critical roles in vertebrate developmental processes, including erythropoiesis, endoderm formation and cardiogenesis. There have been no previous demonstrations of a functional role for any GATA family member being associated with musculoskeletal deve...

journal_title：Developmental biology

authors： Alexandrovich A,Qureishi A,Coudert AE,Zhang L,Grigoriadis AE,Shah AM,Brewer AC,Pizzey JA

更新日期：2008-02-15 00:00:00

abstract：:The Notch signaling pathway controls cell fate choices at multiple steps during cell lineage progression. To produce the cell fate choice appropriate for a particular stage in the cell lineage, Notch signaling needs to interpret the cell context information for each stage and convert it into the appropriate cell fate ...

journal_title：Developmental biology

authors： Das D,Lanner F,Main H,Andersson ER,Bergmann O,Sahlgren C,Heldring N,Hermanson O,Hansson EM,Lendahl U

更新日期：2010-12-15 00:00:00

abstract：:The dorsal air sacs supply oxygen to the flight muscles of the Drosophila adult. This tracheal organ grows from an epithelial tube (the air sac primordium (ASP)) that arises during the third larval instar (L3) from a wing-disc-associated tracheal branch. Since the ASP is generated by a program of both morphogenesis an...

journal_title：Developmental biology

authors： Guha A,Kornberg TB

更新日期：2005-11-01 00:00:00