Early amphibian (anuran) morphogenesis is sensitive to novel gravitational fields.

abstract：:In many animals, the first cue for development is transcripts and/or proteins that are provided maternally and are localized at specific regions of fertilized eggs and early embryos. The ascidian is known to exhibit a mosaic mode of development, which is largely dependent on localized maternal factors. In early Ciona ...

journal_title：Developmental biology

authors： Yamada L

更新日期：2006-08-15 00:00:00

abstract：:Neural crest cells originate in the dorsal neural tube but subsequently undergo an epithelial-to-mesenchymal transition (EMT), delaminate, and migrate to diverse locations in the embryo where they contribute to a variety of derivatives. Cadherins are a family of cell-cell adhesion molecules expressed in a broad range ...

journal_title：Developmental biology

authors： Coles EG,Taneyhill LA,Bronner-Fraser M

更新日期：2007-12-15 00:00:00

abstract：:Interstitial cell migration was characterized in Hydra vulgaris (formerly H. attenuata) and the effects of axial position and tissue injury on migration were investigated. Migrating cells were labeled with the thymidine analog, bromodeoxyuridine, and grafted into unlabeled host polyps. Alternatively, cells were labele...

journal_title：Developmental biology

authors： Teragawa CK,Bode HR

更新日期：1990-03-01 00:00:00

abstract：:The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population, which migrates directionally on defined routes throughout the embryo, contributing to facial structures including cartilage, bone and ganglia. Cadherin-mediated cell-cell adhesion is known to play a crucial role in the directi...

journal_title：Developmental biology

authors： Huang C,Kratzer MC,Wedlich D,Kashef J

更新日期：2016-03-15 00:00:00

abstract：:The cnidarian "planula" larva shows radial symmetry around a polarized, oral-aboral, body axis and comprises two epithelia cell layers, ectodermal and endodermal. This simple body plan is set up during gastrulation, a process which proceeds by a variety of modes amongst the diverse cnidarian species. In the hydrozoan ...

journal_title：Developmental biology

authors： Kraus Y,Chevalier S,Houliston E

更新日期：2020-12-01 00:00:00

abstract：:Similar amounts of expression of a luciferase reporter gene that is driven by the SV40 early promoter are detected in G2 of 1-cell mouse embryo following injection of the male pronucleus in either early or mid/late S. No luciferase activity is observed when the male pronucleus is injected in early S and the embryos an...

journal_title：Developmental biology

authors： Ram PT,Schultz RM

更新日期：1993-04-01 00:00:00

abstract：:Vertebrate heart development requires specification of cardiac precursor cells, migration of cardiac progenitors as well as coordinated cell movements during looping and septation. DM-GRASP/ALCAM/CD166 is a member of the neuronal immunoglobulin domain superfamily of cell adhesion molecules and was recently suggested t...

journal_title：Developmental biology

authors： Gessert S,Maurus D,Brade T,Walther P,Pandur P,Kühl M

更新日期：2008-09-01 00:00:00

abstract：:The segregation of founder cells from the somatic mesoderm is a prerequisite for the formation of body wall muscles in the Drosophila embryo. The myogenic basic helix-loop-helix protein, Nautilus (Nau), is expressed in a subset of these founder cells in medial and lateral positions in the somatic mesoderm. Mutations i...

journal_title：Developmental biology

authors： Ranganayakulu G,Schulz RA,Olson EN

更新日期：1996-05-25 00:00:00

abstract：:This study describes the temporal pattern of posterior positional identity in mouse limb bud cells. To do this wedges of tissue from the posterior edge of mouse limb buds at various stages (limb stages: Wanek et al., 1989b. J. Exp. Zool. 249, 41-49) were grafted to the anterior edge of a host chick embryo wing bud. Gr...

journal_title：Developmental biology

authors： Wanek N,Bryant SV

更新日期：1991-10-01 00:00:00

abstract：:The acquisition of fertilizability in coelomic eggs of Xenopus laevis has been shown to be correlated with the physical, biochemical, and ultrastructural alterations of the egg envelope [coelomic envelope (CE)] induced during the passage of eggs through the pars recta portion of the oviduct. However, no direct evidenc...

journal_title：Developmental biology

authors： Katagiri C,Yoshizaki N,Kotani M,Kubo H

更新日期：1999-06-15 00:00:00

abstract：:The release of intracellular calcium (Ca2+) via either inositol 1,4, 5-trisphosphate receptors (IP3R) or ryanodine receptors (RyR) activates a wide variety of signaling pathways in virtually every type of cell. In the present study we demonstrate that at early stages of development IP3R mRNA and functional IP3-gated C...

journal_title：Developmental biology

authors： Rosemblit N,Moschella MC,Ondriašová E,Gutstein DE,Ondriaš K,Marks AR

更新日期：1999-02-15 00:00:00

abstract：:FoxC, FoxF, FoxL1 and FoxQ1 genes have been shown to be clustered in some animal genomes, with mesendodermal expression hypothesised as a selective force maintaining cluster integrity. Hypotheses are, however, constrained by a lack of data from the Lophotrochozoa. Here we characterise members of the FoxC, FoxF, FoxL1 ...

journal_title：Developmental biology

authors： Shimeld SM,Boyle MJ,Brunet T,Luke GN,Seaver EC

更新日期：2010-04-15 00:00:00

abstract：:Inverse gradients of transcriptional repressors antagonize the transcriptional effector response to morphogens. However, the role of such inverse regulation might not manifest solely from lack of repressors. Sonic hedgehog (Shh) patterns the forebrain by being expressed ventrally; however, absence of antagonizing Gli3...

journal_title：Developmental biology

authors： Shimada IS,Somatilaka BN,Hwang SH,Anderson AG,Shelton JM,Rajaram V,Konopka G,Mukhopadhyay S

更新日期：2019-06-01 00:00:00

abstract：:The hox genes play a central role in organogenesis and are implicated in the formation of hematopoietic stem cells (HSCs). The cdx genes encode homeodomain transcription factors that act as master regulators of the hox genes. In zebrafish, mutations in cdx4 cause a severe, but not complete, deficit in embryonic blood ...

journal_title：Developmental biology

authors： Davidson AJ,Zon LI

更新日期：2006-04-15 00:00:00

abstract：:In many non-mammalian vertebrates, adult dentitions result from cyclical rounds of tooth regeneration wherein simple unicuspid teeth are replaced by more complex forms. Therefore and by contrast to mammalian models, the numerical majority of vertebrate teeth develop shape during the process of replacement. Here, we ex...

journal_title：Developmental biology

authors： Fraser GJ,Bloomquist RF,Streelman JT

更新日期：2013-05-15 00:00:00

abstract：:The adult fungiform taste papilla is a complex of specialized cell types residing in the stratified squamous tongue epithelium. This unique sensory organ includes taste buds, papilla epithelium and lateral walls that extend into underlying connective tissue to surround a core of lamina propria cells. Fungiform papilla...

journal_title：Developmental biology

authors： Liu HX,Ermilov A,Grachtchouk M,Li L,Gumucio DL,Dlugosz AA,Mistretta CM

更新日期：2013-10-01 00:00:00

abstract：:Little is known about the biochemical changes underlying the morphological differentiation of the sea urchin egg during oogenesis. Because of this and the essential role of gamete recognition in fertilization, we studied the developmental expression of the recently identified egg surface receptor for sperm during ooge...

journal_title：Developmental biology

authors： Ohlendieck K,Partin JS,Stears RL,Lennarz WJ

更新日期：1994-09-01 00:00:00

abstract：:In marine teleosts, the aqp1ab water channel plays a vital role in the development of the pelagic egg phenotype. However, the developmental control of aqp1ab activation during oogenesis remains to be established. Here, we report the isolation of the 5'-flanking region of the teleost gilthead seabream aqp1ab gene, in w...

journal_title：Developmental biology

authors： Zapater C,Chauvigné F,Tingaud-Sequeira A,Finn RN,Cerdà J

更新日期：2013-05-15 00:00:00

abstract：:An increase in the incidence of aneuploidy is well documented with increasing maternal age, in particular in human females. Remarkably, little is known regarding the underlying molecular basis for the age-associated increase in aneuploidy, which is a major source of decreased fertility in humans. Using mouse as a mode...

journal_title：Developmental biology

authors： Pan H,Ma P,Zhu W,Schultz RM

更新日期：2008-04-15 00:00:00

abstract：:Rhodopsin is essential for normal photoreceptor development in Drosophila (O'Tousa et al., 1989; Leonard et al., 1992; Kumar and Ready, 1995) and in mice (Humphries et al., 1997). Here we report studies in which a rhodopsin transgene is expressed at restricted stages during the development of Drosophila photoreceptors...

journal_title：Developmental biology

authors： Kumar JP,Bowman J,O'Tousa JE,Ready DF

更新日期：1997-08-01 00:00:00

abstract：:While Wnt signaling is known to be involved in early steps of neural crest development, the mechanism remains unclear. Because Wnt signaling is able to posteriorize anterior neural tissues, neural crest induction by Wnts has been proposed to be an indirect consequence of posteriorization of neural tissues rather than ...

journal_title：Developmental biology

authors： Wu J,Yang J,Klein PS

更新日期：2005-03-01 00:00:00

abstract：:As the germ band shortens in Drosophila melanogaster embryos, cell shape changes cause segments to narrow anteroposteriorly and to lengthen dorsoventrally. One of the genes required for this retraction process is the hindsight (hnt) gene. hnt encodes a nuclear Zinc-finger protein that is expressed in the extraembryoni...

journal_title：Developmental biology

authors： Lamka ML,Lipshitz HD

更新日期：1999-10-01 00:00:00

abstract：:Despite undergoing normal development and acquiring normal morphology and motility, mutations in spe-38 or trp-3/spe-41 cause identical phenotypes in Caenorhabditis elegans-mutant sperm fail to fertilize oocytes despite direct contact. SPE-38 is a novel, four-pass transmembrane protein and TRP-3/SPE-41 is a Ca(2+)-per...

journal_title：Developmental biology

authors： Singaravelu G,Chatterjee I,Rahimi S,Druzhinina MK,Kang L,Xu XZ,Singson A

更新日期：2012-05-15 00:00:00

abstract：:The development of the reproductive system in Caenorhabditis elegans is a well-established model system for patterning and organogenesis. We report the characterization of the cog-1 gene, mutations in which cause novel phenotypes in late patterning in vulval lineages, establishment of the vulva-uterine connection, dev...

journal_title：Developmental biology

authors： Palmer RE,Inoue T,Sherwood DR,Jiang LI,Sternberg PW

更新日期：2002-12-15 00:00:00

abstract：:We report the patterns of migration of Sertoli cells plated on specific substrata, and the influences of testicular peritubular cells on these processes. Data presented indicate that while peritubular cells readily spread when explanted onto Type I collagen, Sertoli cells do not. A delay of 4 to 6 days occurs after Se...

journal_title：Developmental biology

authors： Tung PS,Fritz IB

更新日期：1986-01-01 00:00:00

abstract：:Primitive blood constitutes the ventralmost mesoderm in amphibians, and its cleavage-stage origin reveals important clues about the orientation of the dorsal/ventral axis in the embryo. In recent years, investigators employing various lineage-labeling strategies have reported disparate results for the origin of primit...

journal_title：Developmental biology

authors： Lane MC,Sheets MD

更新日期：2002-08-01 00:00:00

abstract：:TGF-beta (TGFβ) family mediated Smad signaling is involved in mesoderm and endoderm specifications, left-right asymmetry formation and neural tube development. The TGFβ1/2/3 and Activin/Nodal signal transduction cascades culminate with activation of SMAD2 and/or SMAD3 transcription factors and their overactivation are...

journal_title：Developmental biology

authors： Casari A,Schiavone M,Facchinello N,Vettori A,Meyer D,Tiso N,Moro E,Argenton F

更新日期：2014-12-01 00:00:00

abstract：:Border Cells in the Drosophila ovaries are a useful genetic model for understanding the molecular events underlying epithelial cell motility. During stage 9 of egg chamber development they detach from neighboring stretched cells and migrate between the nurse cells to reach the oocyte. RNAi screening allowed us to iden...

journal_title：Developmental biology

authors： De Graeve FM,Van de Bor V,Ghiglione C,Cerezo D,Jouandin P,Ueda R,Shashidhara LS,Noselli S

更新日期：2012-08-01 00:00:00

abstract：:The segmentation of somites from the paraxial mesoderm is a crucial event in vertebrate embryonic development; however, the mechanisms underlying this process are not well understood. In a yeast two-hybrid screen we have identified the novel basic-helix-loop-helix (bHLH) protein cMeso-1 which is expressed in the preso...

journal_title：Developmental biology

authors： Buchberger A,Seidl K,Klein C,Eberhardt H,Arnold HH

更新日期：1998-07-15 00:00:00

abstract：:Enhancers are flexible in terms of their location and orientation relative to the genes they regulate. However, little is known about whether the flexibility can be applied in every combination of enhancers and genes. Enhancer detection with transposable elements is a powerful method to identify enhancers in the genom...

journal_title：Developmental biology

authors： Hozumi A,Yoshida R,Horie T,Sakuma T,Yamamoto T,Sasakura Y

更新日期：2013-03-01 00:00:00