Neural crest induction by the canonical Wnt pathway can be dissociated from anterior-posterior neural patterning in Xenopus.

abstract：:Mesodermal tissue with heart forming potential (cardiogenic mesoderm) is induced during gastrulation. This cardiogenic mesoderm later differentiates into heart muscle tissue (myocardium) and non-muscular heart tissue. Inhibition of Wnt/beta-catenin signaling is known to be required early for induction of cardiogenic m...

journal_title：Developmental biology

authors： Lavery DL,Martin J,Turnbull YD,Hoppler S

更新日期：2008-11-15 00:00:00

abstract：:The Caenorhabditis elegans EGL-17/FGF protein is involved in the gonadal signaling that guides the migrations of sex myoblasts (SMs). egl-17::GFP reporter constructs are expressed dynamically in vulval cell lineages. Expression in the primary vulval cells is correlated with the precise positioning of SMs. We have inve...

journal_title：Developmental biology

authors： Cui M,Han M

更新日期：2003-05-01 00:00:00

abstract：:Cell division is arguably the most fundamental developmental process for single-celled and multicellular organisms alike. The pathway from one cell division to the next is known as the cell cycle. A conserved biochemical regulatory network controls progress along this pathway in plants, animals, and yeasts. This revie...

journal_title：Developmental biology

authors： Jacobs T

更新日期：1992-09-01 00:00:00

abstract：:Named for its assembly near exon-exon junctions during pre-mRNA splicing, the exon junction complex (EJC) regulates multiple aspects of RNA biochemistry, including export of spliced mRNAs from the nucleus and translation. Transcriptome analyses have revealed broad EJC occupancy of spliced metazoan transcripts, yet inh...

journal_title：Developmental biology

authors： Kimball C,Powers K,Dustin J,Poirier V,Pellettieri J

更新日期：2020-01-01 00:00:00

abstract：:To determine whether low oxygen is a stimulus for endothelial cell differentiation and vascular development in the kidney, we examined the effect of low oxygen on rat metanephric organ culture, a model known to recapitulate nephrogenesis in the absence of vessels. After 6 days in culture in standard (20% O2) or low ox...

journal_title：Developmental biology

authors： Tufro-McReddie A,Norwood VF,Aylor KW,Botkin SJ,Carey RM,Gomez RA

更新日期：1997-03-15 00:00:00

abstract：:Antibodies to nonerythroid alpha spectrin (p 230) were used to study the distribution of this polypeptide in mouse germ cells, zygote, and early embryonic cells. In the primordial germ cells, fetal oocytes, and spermatogonia, spectrin was found predominantly in the form of a narrow condensed subplasmalemmal band, as i...

journal_title：Developmental biology

authors： Damjanov I,Damjanov A,Lehto VP,Virtanen I

更新日期：1986-03-01 00:00:00

abstract：:One of the earliest steps in embryonic development is the establishment of the future body axes. Morphological and molecular data place the Ambulacraria (echinoderms and hemichordates) within the Deuterostomia and as the sister taxon to chordates. Extensive work over the last decades in echinoid (sea urchins) echinode...

journal_title：Developmental biology

authors： Röttinger E,Martindale MQ

更新日期：2011-06-01 00:00:00

abstract：:The spermatid nucleus and cytoplasm undergo dramatic morphological modifications during spermatid differentiation into mature sperm. Some of the external force causing this nuclear shaping is generated by a microtubular structure termed the manchette, which attaches to the perinuclear ring of the spermatid. Here, we r...

journal_title：Developmental biology

authors： Tarsounas M,Pearlman RE,Moens PB

更新日期：2001-08-15 00:00:00

abstract：:Unidirectional blue light directs the rhizoid-thallus axis in the apolar zygotes of Fucus and Pelvetia. Here, it is shown that blue light (but not red light) increased cyclic GMP levels of Pelvetia zygotes by about a factor of 2. When the increase in cyclic GMP was blocked by a guanylyl cyclase inhibitor, photopolariz...

journal_title：Developmental biology

authors： Robinson KR,Miller BJ

更新日期：1997-07-01 00:00:00

abstract：:A series of chimeras was generated by injecting single normal, parthenogenetic, or androgenetic blastomeres carrying transgenic markers under the zona pellucida of nontransgenic eight-cell embryos. These chimeras were cultured to the blastocyst stage and sectioned, and the transgenic component was detected by in situ ...

journal_title：Developmental biology

authors： Thomson JA,Solter D

更新日期：1989-02-01 00:00:00

abstract：:Induction and branching morphogenesis of the prostate are dependent on androgens, which act via the mesenchyme to induce prostatic epithelial development. One mechanism by which the mesenchyme may regulate the epithelium is through secreted growth factors such as FGF-10. We have examined the male reproductive tract of...

journal_title：Developmental biology

authors： Donjacour AA,Thomson AA,Cunha GR

更新日期：2003-09-01 00:00:00

abstract：:Here we describe a novel set of peptidergic neurons conserved throughout all developmental stages in the Drosophila central nervous system (CNS). We show that a small complement of 28 apterous-expressing cells (Ap-let neurons) in the ventral nerve cord (VNC) of Drosophila larvae co-express numerous gene products. The ...

journal_title：Developmental biology

authors： Park D,Han M,Kim YC,Han KA,Taghert PH

更新日期：2004-05-01 00:00:00

abstract：:Elastic fibers are produced during fetal and neonatal periods, and by maturity elastin expression has ceased. Fetal bovine hyaline chondrocytes acquired an elastogenic phenotype within 24 hr after isolation from the tissue, even though the tissue does not produce elastic fibers or tropoelastin mRNA in vivo. By multipl...

journal_title：Developmental biology

authors： Lee KA,Pierce RA,Davis EC,Mecham RP,Parks WC

更新日期：1994-05-01 00:00:00

abstract：:Vertebrate morphology has been evolutionarily modified by natural and/or artificial selection. The morphological variation of goldfish is a representative example. In particular, the twin-tail strain of ornamental goldfish shows highly diverged anal and caudal fin morphology: bifurcated anal and caudal fins. Recent mo...

journal_title：Developmental biology

authors： Abe G,Ota KG

更新日期：2017-07-15 00:00:00

abstract：:Macronuclei of Tetrahymena thermophila contain a typical H1 which has been shown to be missing from micronuclei. Instead, micronuclei contain three unique polypeptides, alpha, beta, and gamma, which are associated with linker regions of micronuclear chromatin. In this report polyclonal antibodies raised against macron...

journal_title：Developmental biology

authors： Chicoine LG,Wenkert D,Richman R,Wiggins JC,Allis CD

更新日期：1985-05-01 00:00:00

abstract：:CHARGE syndrome is caused by spontaneous loss-of-function mutations to the ATP-dependant chromatin remodeller chromodomain-helicase-DNA-binding protein 7 (CHD7). It is characterised by a distinct pattern of congenital anomalies, including cardiovascular malformations. Disruption to the neural crest lineage has previou...

journal_title：Developmental biology

authors： Payne S,Burney MJ,McCue K,Popal N,Davidson SM,Anderson RH,Scambler PJ

更新日期：2015-09-01 00:00:00

abstract：:During mammalian spermiogenesis transitional proteins and protamines replace histones on the DNA as the chromatin condenses. While previous studies suggested that histone genes are inactive postmeiotically, we have shown both by steady-state RNA analysis and nuclear run-off transcription assays that histone 2b (H2b) t...

journal_title：Developmental biology

authors： Moss SB,Challoner PB,Groudine M

更新日期：1989-05-01 00:00:00

abstract：:The corepressor SMRT acts on a range of transcription factors, including the retinoid and thyroid hormone nuclear receptors. The carboxy-terminal region of SMRT contains CoRNR box motifs that mediate these interactions. We have shown, in Xenopus, that SMRT can exist as isoforms containing either two or three CoRNR box...

journal_title：Developmental biology

authors： Malartre M,Short S,Sharpe C

更新日期：2006-04-15 00:00:00

abstract：:Wnt-4, a member of the Wnt family of secreted signaling molecules, is essential for nephrogenesis, but its expression in the presumptive medulla suggests additional developmental roles in kidney organogenesis. We demonstrate here that Wnt-4 signaling plays also a role in the determination of the fate of smooth muscle ...

journal_title：Developmental biology

authors： Itäranta P,Chi L,Seppänen T,Niku M,Tuukkanen J,Peltoketo H,Vainio S

更新日期：2006-05-15 00:00:00

abstract：:The fate of bacteriophage lambda-DNA was examined after injection into the fertilized eggs of Xenopus laevis. Injection of a large amount of lambda-DNA (ca. 24 ng) into a fertilized Xenopus egg induced the formation around the injected DNA of a giant nucleus-like structure which was surrounded by an apparently normal ...

journal_title：Developmental biology

authors： Shiokawa K,Sameshima M,Tashiro K,Miura T,Nakakura N,Yamana K

更新日期：1986-08-01 00:00:00

abstract：:Results of numerous experiments indicate that the transient rise in intracellular Ca2+ following sperm-egg fusion is essential for the subsequent events that constitute egg activation. Some events of egg activation, e.g., cortical granule exocytosis, however, appear more sensitive to intracellular Ca2+ than other even...

journal_title：Developmental biology

authors： Xu Z,Lefevre L,Ducibella T,Schultz RM,Kopf GS

更新日期：1996-12-15 00:00:00

abstract：:Previous work in our laboratory has shown that a 62- to 64-kDa protein was a major component of the perinuclear ring of manchettes fractionated from rat spermatids. Mass spectrometry analysis of this protein indicated the presence of a glycine-rich domain homologous to human keratin 9 (K9). Several antibodies to K9, r...

journal_title：Developmental biology

authors： Mochida K,Rivkin E,Gil M,Kierszenbaum AL

更新日期：2000-11-15 00:00:00

abstract：:The large ampullate glands of the orb-web spider, Nephila clavipes provide massive amounts of fibroin throughout the lifetime of the adult female. We have developed methods to culture the glands and manipulate their biosynthetic activity. This has allowed us to monitor a series of molecular events that precede silk pr...

journal_title：Developmental biology

authors： Candelas GC,Arroyo G,Carrasco C,Dompenciel R

更新日期：1990-07-01 00:00:00

abstract：:In mouse chimeras with parthenogenetic cell contribution, the skeletal musculature appears to be largely devoid of parthenogenetically derived cells. To analyze the appearance and early distribution of myotomal cells in parthenotes, we determined the expression of the muscle-specific transcription factors myogenin, MY...

journal_title：Developmental biology

authors： Fundele R,Bober E,Arnold HH,Grim M,Bender R,Wilting J,Christ B

更新日期：1994-01-01 00:00:00

abstract：:Cytoskeletal intermediate filaments were studied in muscular dysgenesis (mdg) and tetrodotoxin-treated inactive mouse embryo muscle cultures during myofibrillogenesis. Both muscular dysgenesis and tetrodotoxin-treated muscles are characterized in vitro by a total lack of contractile activity and an abnormal developmen...

journal_title：Developmental biology

authors： Tassin AM,Pinçon-Raymond M,Paulin D,Rieger F

更新日期：1988-09-01 00:00:00

abstract：:Zygotic Wnt signaling has been shown to be involved in dorsoventral mesodermal patterning in Xenopus embryos, but how it regulates different myogenic gene expression in the lateral mesodermal domains is not clear. Here, we use transient exposure of embryos or explants to lithium, which mimics Wnt/beta-catenin signalin...

journal_title：Developmental biology

authors： Shi DL,Bourdelas A,Umbhauer M,Boucaut JC

更新日期：2002-05-01 00:00:00

abstract：:Biologists have long recognized that dramatic bending of a cell sheet may be driven by even modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like these are at the core of many of the morphogenetic movements that shape animal form during development, driving processes such as gastr...

journal_title：Developmental biology

authors： Sawyer JM,Harrell JR,Shemer G,Sullivan-Brown J,Roh-Johnson M,Goldstein B

更新日期：2010-05-01 00:00:00

abstract：:To investigate the molecular regulation of embryonic somite formation and development, we have cloned the full-length cDNA and characterized the embryonic expression profile of chicken Paraxis, a member of a novel family of basic helix-loop-helix (bHLH) proteins, which has been suggested to play a role in paraxial mes...

journal_title：Developmental biology

authors： Barnes GL,Alexander PG,Hsu CW,Mariani BD,Tuan RS

更新日期：1997-09-01 00:00:00

abstract：:Pulses of ecdysteroids induce dramatic changes in gene expression that direct the early stages of Drosophila metamorphosis. This gene activity is reflected by the appearance of early and late puffs in the salivary gland polytene chromosomes. Curiously, the early puff genes that have been studied to date are induced by...

journal_title：Developmental biology

authors： Baehrecke EH,Thummel CS

更新日期：1995-09-01 00:00:00

abstract：:Neurons of the dorsal hindbrain and spinal cord are central in receiving, processing and relaying sensory perception and participate in the coordination of sensory-motor output. Numerous cellular and molecular mechanisms that underlie neuronal development in both regions of the nervous system are shared. We discuss he...

journal_title：Developmental biology

authors： Hernandez-Miranda LR,Müller T,Birchmeier C

更新日期：2017-12-01 00:00:00