Induction of matrix metalloproteinase-9 in mice during Toxocara canis larvae migration.

Abstract:

:The relationships between inflammation in organs with Toxocara canis larval migration and matrix metalloproteinase-9 (MMP-9) were investigated following the infection of mice with 1,000 infective eggs. Gelatinase activity was defined by gelatin zymography, optimum pH, inhibitor specificity and Western blot analysis. MMP-9 activity was present in the lungs, liver, muscles, and brain during T. canis larval migration. This enzyme had a molecular weight of about 94 kDa and showed maximum activity in the pH range of 6-8. The increased MMP-9 proteinases coincided with larval recovery and the degree of inflammation among the four organs. These results suggest that MMP-9 may be associated with the inflammatory reaction to larval toxocariasis during early migration, and may therefore be a useful marker during T. canis larvae migration.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Lai SC,Chen KM,Chen HC,Lee HH

doi

10.1007/s00436-004-1271-9

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

193-200

issue

3

eissn

0932-0113

issn

1432-1955

journal_volume

95

pub_type

杂志文章
  • Dermatological and parasitological evaluation of infestations with chewing lice (Werneckiella equi) on horses and treatment using imidacloprid.

    abstract::Lice infestations in horses caused by the chewing louse Werneckiella (Damalinia) equi are observed worldwide. In the present study, the efficacy of 10% imidacloprid was tested on horses naturally infested with lice. Two groups of animals received a double application of 4 ml and 8 ml Advantage 10% spot-on on day 0 and...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-005-1379-6

    authors: Mencke N,Larsen KS,Eydal M,Sigurethsson H

    更新日期:2005-08-01 00:00:00

  • Role of small GTPases in Trypanosoma cruzi invasion in MDCK cell lines.

    abstract::Trypanosoma cruzi can modulate a large number of host intracellular responses during its invasion. GTPases such as RhoA, Rac1 and Cdc42 are examples of molecules that could be activated at this moment and trigger changes in the pattern of F-actin cytoskeleton leading to the formation of structures like stress fibers, ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-005-1333-7

    authors: Dutra JM,Bonilha VL,De Souza W,Carvalho TM

    更新日期:2005-06-01 00:00:00

  • Early developmental stages of Ascaris lumbricoides featured by high-resolution mass spectrometry.

    abstract::Ascaris lumbricoides is responsible for a highly disseminated helminth parasitic disease, ascariosis, a relevant parasitosis that responds for great financial burden on the public health system of developing countries. In this work, metabolic fingerprinting using high-resolution mass spectrometry (HRMS) was employed t...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-016-5183-2

    authors: Melo CF,Esteves CZ,de Oliveira RN,Guerreiro TM,de Oliveira DN,Lima EO,Miné JC,Allegretti SM,Catharino RR

    更新日期:2016-11-01 00:00:00

  • Identification of Haemonchus species in domestic ruminants based on morphometrics of spicules.

    abstract::An easy and rapid tool for the individual identification of Haemonchus species in domestic ruminants might be very useful in the study of natural populations, especially when two (or three) species are sympatric. Techniques based on cytology, cuticular-ridge patterns, sublateral hypodermic chords, or molecular biology...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360050213

    authors: Jacquiet P,Cabaret J,Cheikh D,Thiam E

    更新日期:1997-01-01 00:00:00

  • Occurrence of Leishmania infantum and associated histological alterations in the genital tract and mammary glands of naturally infected dogs.

    abstract::The objectives of this study were to evaluate the occurrence of Leishmania infantum in the male and female genital tract and female mammary glands of dogs and the parasite burden and to identify histological alterations associated with this protozoan. Twenty male and 20 female Leishmania-seropositive dogs with isolati...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-016-4987-4

    authors: Boechat VC,Mendes Junior AA,Madeira Mde F,Ferreira LC,Figueiredo FB,Rodrigues Fd,Oliveira Vda C,de Oliveira Rde V,Menezes RC

    更新日期:2016-06-01 00:00:00

  • Ultrastructure of sporogony in Babesia equi in salivary glands of adult female Boophilus microplus ticks.

    abstract::The development of Babesia equi was studied in the salivary glands of adult female ticks, Boophilus microplus, using a transmission electron microscope (TEM). Engorged nymphs were obtained from splenectomized foals experimentally infected with B. equi and fed in the adult phase for 5 days on rabbits. Sporogony in B. e...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360050359

    authors: Guimarães AM,Lima JD,Ribeiro MF,Camargos ER,Bozzi IA

    更新日期:1998-01-01 00:00:00

  • The Gyrodactylus (Monogenea, Gyrodactylidae) parasite fauna of freshwater sand gobies (Teleostei, Gobioidei) in their centre of endemism, with description of seven new species.

    abstract::While Gobioidei comprises showcases of (adaptive) radiation, the scientific interest they yielded did not ensure full understanding of goby biodiversity. Even in a well-studied region like Europe, wide knowledge gaps remain. Sand gobies represent one of the few clades whose monogenean parasites have been thoroughly st...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-013-3693-8

    authors: Vanhove MP,Economou AN,Zogaris S,Giakoumi S,Zanella D,Volckaert FA,Huyse T

    更新日期:2014-02-01 00:00:00

  • PROTOGIM: a novel tool to search motifs and domains in hypothetical proteins of protozoan genomes.

    abstract::Whole sequencing of protozoan trypanosomatid genomes revealed the presence of several predicted unknown genes coding for hypothetical proteins. Pairwise, alignment-based, computational methods available online are unable to identify the function of these sequences. To detect clues to identify the function of hypotheti...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-005-0064-0

    authors: Cestari IS,Haver NJ,Barbosa-Silva A,Ramirez MI

    更新日期:2006-03-01 00:00:00

  • Trypanosoma cruzi: evaluation of (-)-cubebin derivatives activity in the messenger RNAs processing.

    abstract::No fully effective treatment has been developed since the discovery of Chagas' disease. Since drug-resistant Trypanosoma cruzi strains are occurring and the current therapy is effective in the acute phase but with various adverse side effects, more studies are needed to characterize the susceptibility of T. cruzi to n...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-011-2275-x

    authors: Andrade e Silva ML,Cicarelli RM,Pauletti PM,Luz PP,Rezende KC,Januário AH,da Silva R,Pereira AC,Bastos JK,de Albuquerque S,Magalhães LG,Cunha WR

    更新日期:2011-08-01 00:00:00

  • Ultrastructural alterations induced by nifurtimox and another nitro derivative on epimastigotes of Trypanosoma cruzi.

    abstract::We report the ultrastructural alterations induced on epimastigotes by nifurtimox and 5-nitro-2-thienyl-malononitrile (5NO2TM), a novel compound with anti-Trypanosoma cruzi activity. Parasites treated with concentrations of nifurtimox lower than usually employed for this kind of study showed vacuolisation, alterations ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360100497

    authors: Muelas-Serrano S,Pérez-Serrano J,Gómez-Barrio A,Arán VJ,Rodríguez-Caabeiro F

    更新日期:2002-02-01 00:00:00

  • Gastrointestinal parasites of captive European bison Bison bonasus (L.) with a sign of reduced efficacy of Haemonchus contortus to fenbendazole.

    abstract::The history of European bison Bison bonasus Linnaeus, 1758 has been stormy since its extinction in the wild after the First World War. Due to the fact that the species was restored from just 12 founders, further expansion has suffered from low genetic variability, rendering the bison vulnerable to various pathogens du...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5663-z

    authors: Pyziel AM,Björck S,Wiklund R,Skarin M,Demiaszkiewicz AW,Höglund J

    更新日期:2018-01-01 00:00:00

  • Ultrastructural localisation of FMRFamide- and pancreatic polypeptide-immunoreactivities within the central nervous system of the liver fluke, Fasciola hepatica (Trematoda, Digenea).

    abstract::A post-embedding immunogold technique was used to examine the subcellular distribution of immunoreactivities to the invertebrate peptide, FMR-Famide, and to vertebrate pancreatic polypeptide (PP) within the central nervous system of the trematode, Fasciola hepatica. Gold labeling of peptide was localised exclusively o...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00933778

    authors: Brownlee DJ,Brennan GP,Halton DW,Fairweather I,Shaw C

    更新日期:1994-01-01 00:00:00

  • Fatty acid composition of Echinostoma trivolvis (Trematoda) rediae and adults and of the digestive gland-gonad complex of Helisoma trivolvis (Gastropoda) infected with the intramolluscan stages of this echinostome.

    abstract::Gas-liquid chromatographic studies were done to determine the fatty acid composition of the digestive gland-gonad (DGG) complex of Helisoma trivolvis snails infected with the intramolluscan stages of Echinostoma trivolvis, of rediae freed from the DGG, of uninfected DGG, and of 41-day-old adult worms grown in golden h...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00931585

    authors: Fried B,Rao KS,Sherma J,Huffman JE

    更新日期:1993-01-01 00:00:00

  • Mitochondrial haplotype diversity of Gyrodactylus thymalli (Platyhelminthes; Monogenea): extended geographic sampling in United Kingdom, Poland, and Norway reveals further lineages.

    abstract::In recent years, the mitochondrial haplotype diversity of the monogenean ectoparasites Gyrodactylus salaris Malmberg, 1957 on Atlantic salmon and G. thymalli Zitnan, 1960 on grayling has been studied intensively to understand the taxonomy and phylogeography of the two species. According to these studies, neither speci...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-006-0423-5

    authors: Hansen H,Bakke TA,Bachmann L

    更新日期:2007-05-01 00:00:00

  • Mechanical recovery of inhibited cyathostomin larvae from equine intestinal tissue.

    abstract::The Stomacher is very widely used in food and medical research for extracting tissues. To determine whether nematode larvae were disrupted by the Stomacher, L3 larvae of Haemonchus contortus were homogenised for up to 40 min at full power but no larval disruption occurred. Therefore, tissue from the mucosa and submuco...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-009-1473-2

    authors: Glover ID,Henry GM,Townsend NB,Coles GC

    更新日期:2009-08-01 00:00:00

  • Some factors influencing transmission of toxoplasma in pregnant rats fed cysts.

    abstract::An overall 44% transplacental transmission rate was observed in 221 rats fed cysts of 12 Toxoplasma strains at 15 days of pregnancy, with a range of 0-90% transmission. Considerable variability in the transmission rate was seen among different groups of rats that received similar Toxoplasma inocula; this is attributed...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360100486

    authors: Freyre A,Correa O,Falcón J,Mendez J,González M,Venzal JM

    更新日期:2001-11-01 00:00:00

  • New insight into praziquantel against various developmental stages of schistosomes.

    abstract::Praziquantel, due to high efficacy, excellent tolerability, few and transient side effects, simple administration, and competitive cost, is virtually the only drug of choice for treatment of human schistosomiasis. Treatment of schistosomiasis has shown great advances with the introduction of the drug into the therapeu...

    journal_title:Parasitology research

    pub_type: 杂志文章,评审

    doi:10.1007/s00436-011-2670-3

    authors: Wu W,Wang W,Huang YX

    更新日期:2011-12-01 00:00:00

  • The precocious oncomiracidium of Neoentobdella parvitesticulata (Monogenea: Capsalidae: Entobdellinae).

    abstract::The oncomiracidium (larva) of the entobdelline Neoentobdella parvitesticulata (Monogenea: Capsalidae), adults of which parasitise the skin of the stingray Himantura fai (Dasyatidae) at Heron Island, Great Barrier Reef, Queensland, Australia, is described. The larva undergoes precocious development (progenesis) in the ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-005-1399-2

    authors: Whittington ID,Kearn GC

    更新日期:2005-07-01 00:00:00

  • Geographical distribution of ticks in Turkey.

    abstract::Turkey's tick fauna is composed of about 32 species in two families and ten genera in mammals, reptiles, and birds. The ticks of veterinary significance in the family Ixodidae comprise seven genera with 28 different species. Ixodes spp. are mostly seen in northern Turkey. It is likely that the high rainfall and the in...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-007-0694-5

    authors: Aydin L,Bakirci S

    更新日期:2007-09-01 00:00:00

  • Evaluation of boric acid sugar baits against Aedes albopictus (Diptera: Culicidae) in tropical environments.

    abstract::Attractive toxic sugar bait (active ingredient, 1% boric acid) was evaluated against Aedes albopictus Skuse populations in the laboratory, semi-field trials, and field trials in residential communities in St. Augustine, Florida. Laboratory evaluations of boric acid sugar baits applied to the plant Pentas lanceolata (R...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-013-3312-8

    authors: Naranjo DP,Qualls WA,Müller GC,Samson DM,Roque D,Alimi T,Arheart K,Beier JC,Xue RD

    更新日期:2013-04-01 00:00:00

  • Strongyloides stercoralis hyper-infection syndrome in HIV+/AIDS patients in Iran.

    abstract::Strongyloides stercoralis is an intestinal nematode in humans, distributed through tropical and subtropical regions of the world. In most individuals, the infection has a chronic nature due to auto-infection at the low level. Accelerated auto-infection, mainly after an alteration in immune status, can cause a syndrome...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-007-0531-x

    authors: Meamar AR,Rezaian M,Mohraz M,Hadighi R,Kia EB

    更新日期:2007-08-01 00:00:00

  • Comparative studies on the proteomic expression patterns in the third- and fifth-stage larvae of Angiostrongylus cantonensis.

    abstract::Angiostrongylus cantonensis is an important zoonotic parasite causing eosinophilic meningitis and eosinophilic meningoencephalitis in humans. In this study, the protein expression profiles of the infective third- and pathogenic fifth-stage larvae (L3 and L5) of this parasite were compared by proteomic techniques. Isol...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-014-4024-4

    authors: Chen KY,Cheng CJ,Yen CM,Tang P,Wang LC

    更新日期:2014-10-01 00:00:00

  • Morphometric and molecular analyses of Carassotrema koreanum Park 1938 and Elonginurus mugilus Lu 1995 (Digenea: Haploporidae) Srivastava, 1937 from the Russian Far East and Vietnam.

    abstract::Adult worms that belong to Carassotrema Park 1938 and Elonginurus Lu, 1955 were found in the intestine of Carassius gibelio Bloch, 1782 from the southern Russian Far East and Mugil cephalus Linnaeus, 1758 from northern Vietnam, respectively. Morphometric parameters, geographic location and host species composition of ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-019-06328-4

    authors: Atopkin DM,Besprozvannykh VV,Ha ND,Nguyen HV,Khamatova AY,Vainutis KS

    更新日期:2019-07-01 00:00:00

  • Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes.

    abstract::A quantitative colorimetric assay using the oxidation-reduction indicator resazurin was developed to measure cytotoxicity of compounds against the protozoan parasite Trypanosoma cruzi. This method is based on the detection of colorimetric changes caused by the oxidation (blue) and reduction (pink) capabilities of resa...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-006-0126-y

    authors: Rolón M,Vega C,Escario JA,Gómez-Barrio A

    更新日期:2006-07-01 00:00:00

  • Spermiogenesis in the pseudophyllid cestode Eubothrium crassum (Bloch, 1779).

    abstract::Spermiogenesis of the pseudophyllidean tapeworm Eubothrium crassum has been described by the aid of transmission electron microscopy for the first time. Initially, early spermatids form a distal cytoplasmic protrusion, a differentiation zone containing a small electron-dense, apically oriented region. Out of this regi...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360100392

    authors: Brunanská M,Nebesárová J,Scholz T,Fagerholm HP

    更新日期:2001-08-01 00:00:00

  • Late development and fertility of adult worms derived from gamma-irradiated first-stage larvae of Angiostrongylus cantonensis.

    abstract::Effects of gamma ray irradiation on the first-stage larvae of Angiostrongylus cantonensis were studied. Compared to the non-treated controls, infection of rats with third-stage larvae which developed from irradiated first-stage larvae resulted in reduced recovery rates of adults. There was also a change in the male-fe...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00536473

    authors: Ishii AI,Honda M,Sano M

    更新日期:1987-01-01 00:00:00

  • Taxonomic composition and endemism of the helminth fauna of freshwater fishes of Mexico.

    abstract::We examine the taxonomic composition and endemism of adult helminth parasites of freshwater fishes of Mexico, with regard to the main hydrological basins of the country. A presence-absence matrix, including every species of adult helminth parasites of freshwater fishes from 23 Mexican hydrological basins was compiled ...

    journal_title:Parasitology research

    pub_type: 杂志文章,评审

    doi:10.1007/s00436-012-3175-4

    authors: Salgado-Maldonado G,Quiroz-Martínez B

    更新日期:2013-01-01 00:00:00

  • Pseudocyst forms of Trichomonas vaginalis from cervical neoplasia.

    abstract::Trichomonas vaginalis, a flagellated protozoan parasite causes a variety of adverse health consequences in both men and women. The parasite exists in the trophozoite and the pseudocystic stage. The study reports for the first time that pseudocyst forms of T. vaginalis isolated from cervical neoplasia (CN) patients dem...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-012-2848-3

    authors: Afzan MY,Suresh K

    更新日期:2012-07-01 00:00:00

  • Rapid detection of Wuchereria bancrofti in mosquitoes by LightCycler polymerase chain reaction and melting curve analysis.

    abstract::A LightCycler real-time polymerase chain reaction (PCR) assay was developed to detect Wuchereria bancrofti DNA in blood-fed mosquitoes. The assay is based on fluorescence melting curve analysis of the PCR product generated from a family of repeated DNA elements: the 182 bp SspI repeat, specific to the genus Wuchereria...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-004-1221-6

    authors: Lulitanond V,Intapan PM,Pipitgool V,Choochote W,Maleewong W

    更新日期:2004-11-01 00:00:00

  • Beta diversity of gastrointestinal helminths in two closely related South African rodents: species and site contributions.

    abstract::A fundamental aim of parasite ecology is to understand the mechanisms behind spatial variation in diversity and structure of parasite assemblages. To understand the contribution of individual parasite species and their assemblages to spatial variation in parasite communities, we examined species contributions to beta ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-019-06411-w

    authors: Spickett A,van der Mescht L,Junker K,Krasnov BR,Haukisalmi V,Matthee S

    更新日期:2019-10-01 00:00:00