Abstract：
:Trichomonas vaginalis, a flagellated protozoan parasite causes a variety of adverse health consequences in both men and women. The parasite exists in the trophozoite and the pseudocystic stage. The study reports for the first time that pseudocyst forms of T. vaginalis isolated from cervical neoplasia (CN) patients demonstrated distinct, different and significant in vitro growth profiles when grown in vitro cultures from day 1 up to day 5 (p<0.05, Mann-Whitney test) when compared with the same life cycle stages isolated from non-cervical neoplasia but symptomatic patients (NCN). Pseudocysts from CN and NCN isolates remained viable in distilled water until 3 h 10 min and 2 h 10 min, respectively. The nucleus of pseudocysts in CN isolates using acridine orange and DAPI showed more intense staining revealing higher nuclear content. The FITC-labeled Concanavalin A stained stronger green fluorescence with surface of pseudocysts in CN isolates showing more rough and creased surface with higher numbers of deep micropores with larger numbers of chromatin masses, vacuoles, and hydrogenosomes. The study confirms that pseudocystic stage from CN, despite the uniformity in appearance of being rounded and showing no motility without a true cyst wall under light microscopy, demonstrated different biochemical, surface, and ultrastructural properties. The study provides evidence that phenotypic variant forms of pseudocysts does exist and possibly does play a role in exacerbating cervical cancer.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Afzan MY,Suresh Kdoi
10.1007/s00436-012-2848-3subject
Has Abstractpub_date
2012-07-01 00:00:00pages
371-81issue
1eissn
0932-0113issn
1432-1955journal_volume
111pub_type
杂志文章abstract：:Representatives of Apicomplexa perform various kinds of movements that are linked to the different stages of their life cycle. Ancestral apicomplexan lineages, including gregarines, represent organisms suitable for research into the evolution and diversification of motility within the group. The vermiform trophozoites...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06381-z
更新日期：2019-09-01 00:00:00
abstract：:Fatty acids, especially those from phospholipids (PLFA), are essential membrane components that are present in relatively constant proportions in biological membranes under natural conditions. However, under harmful growth conditions, such as diseases, environmental changes, and chemical exposure, the fatty acid propo...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3621-y
更新日期：2014-01-01 00:00:00
abstract：:Many malaria-endemic areas are also associated with high rates of human immunodeficiency virus (HIV) infection. An understanding of the chemotherapeutic interactions that occur during malaria and HIV co-infections is important. Our previous studies have demonstrated that some antiretroviral protease inhibitors are eff...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2427-z
更新日期：2011-12-01 00:00:00
abstract：:The peritoneal cavity (PNC) and intestine of northern fur seal (Callorhinus ursinus) pups and California sea lion (Zalophus californianus) pups that died in late July and early August, 2003, on San Miguel Island, California, were examined for hookworms. Prevalence and morphometric studies were done with the hookworms ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2289-4
更新日期：2011-09-01 00:00:00
abstract：:Global pollinator decline has recently been discussed in the context of honey and bumble bee infections from various pathogens including viruses, bacteria, microsporidia and mites. The microsporidian pathogens Nosema apis, Nosema ceranae and Nosema bombi may in fact be major candidates contributing to this decline. Di...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2640-9
更新日期：2012-04-01 00:00:00
abstract：:Discoid granules were isolated from the tegument of adult Schistosoma mansoni by differential centrifugation of freeze-thaw extracts. Comparison of proteins and glycoproteins from discoid granules, surface membranes and the soluble fraction implied that discoid granules and the surface membrane were functionally linke...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00539573
更新日期：1988-01-01 00:00:00
abstract：:The existing armament of drugs for the treatment and prevention of malaria is inadequate due to development of resistance. In addition to this due to lack of economic enticement the rate of new drug development and new drug discovery in the segment of parasitic diseases is very low as compared to the other segments. T...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1789-y
更新日期：2010-05-01 00:00:00
abstract：:Saliva has been suggested as an easily accessible and a noninvasive diagnostic alternative for detection of antibodies. To identify and characterize Schistosoma japonicum (S. japonicum) antigens that are recognized by saliva of infected host, we have used a pool of saliva from infected patients to immunoscreen an egg ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1575-x
更新日期：2009-10-01 00:00:00
abstract：:Albendazole is known as the drug of choice for medical treatment of cystic echinococcosis (CE). Albendazole sulfoxide (ABZ-SO), as the main active metabolite of albendazole, has low efficacy in the disease due to low water solubility and poor absorptivity. PLGA nanoparticles (NPs) enhance the dissolution of poorly sol...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06901-2
更新日期：2020-12-01 00:00:00
abstract：:The DNA content of the developmental stages within the life cycle of Babesia divergens was measured by means of fluorescence microscopy using the DNA-specific bisbenzimide Hoechst 33258. By comparing the mean relative fluorescence intensities, the assumption of sexual reproduction in the gut of the tick vector (Ixodes...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00930815
更新日期：1990-01-01 00:00:00
abstract：:This is the first report of cryptosporidiosis in a bactrian camel (Camelus bactrianus) in China. Two Cryptosporidium isolates derived from the same bactrian camel (3-year-old) in November 2005 and April 2006 were characterized using sequence and phylogenetic analysis of the small-subunit rRNA (18S rRNA), 70-kDa heat s...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0851-x
更新日期：2008-04-01 00:00:00
abstract：:Eimeria spp. multiply within the intestinal tract causing severe inflammatory responses. Chitosan (CS), meanwhile, has been shown to exhibit anti-inflammatory activities in different experimental models. Here, we investigated the effect of CS on the outcome of inflammation caused by Eimeria papillata in the mouse inte...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5035-0
更新日期：2016-07-01 00:00:00
abstract：:The efficacy of metaphylactic treatment with toltrazuril (Baycox 5% suspension) against natural infections with Eimeria bovis and/or Eimeria zuernii in calves was investigated. The study was conducted with 208 calves on five calf-rearing farms in Germany and the Czech Republic. All participating farms had a notable in...
journal_title：Parasitology research
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00436-005-1457-9
更新日期：2005-10-01 00:00:00
abstract：:We have recently demonstrated that the antimicrotubule drug oryzalin inhibits the growth of Entamoeba invadens as well as E. histolytica, the former being more resistant to the drug than the latter, and that effective doses of oryzalin are higher for Entamoeba than for the other parasitic protozoa examined thus far. T...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/pl00008542
更新日期：2000-08-01 00:00:00
abstract：:Tick-borne intracellular protozoan parasites of the Theileria genus infect a wide range of both domestic and wild animals. In the present study, we describe the first PCR detection of Theileria luwenshuni in the blood of goats in Myanmar. Nested PCR targeting the Theileria 18S rRNA gene resulted in seven positive goat...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6073-6
更新日期：2018-10-01 00:00:00
abstract：:A taste-enhancement process for cold-stored, raw shell-stock Crassostrea virginica oysters (i.e., application of table salt to shells) when externally contaminated with human enteropathogens intensified spillage of these enteropathogens to oyster' storage containers (77% compared to 27% for controls) but did not, howe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0664-y
更新日期：2007-11-01 00:00:00
abstract：:In forensic investigations, immature stages of the fly (egg, larva, or puparia) can be used as entomological evidence at death scenes, not only to estimate the postmortem interval (PMI), analyze toxic substances, and to determine the manner of death but also to indicate the movement of a corpse in homicide cases. Of t...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0660-2
更新日期：2007-10-01 00:00:00
abstract：:During a survey lasting from 1990 to 2008, we captured 4,113 Asian house rats, Rattus tanezumi Temminck 1844 (Rodentia: Muridae) from 28 counties of Yunnan Province in southwestern China. From these rats, a total of 19,304 gamasid mites (Acari: Mesostigmata) were collected and identified as comprising 50 different spe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3354-y
更新日期：2013-05-01 00:00:00
abstract：:Blastocystis is an enteric protozoan parasite commonly found in humans and animals. Phylogenetic and genotypic analyses have shown that Blastocystis exhibits extreme genetic diversity, and humans are host to a number of zoonotic isolates. In the present study, the prevalence of Blastocystis in 276 stool samples from a...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0808-0
更新日期：2008-03-01 00:00:00
abstract：:A study of development of Eimeria tenella in chickens fed high n-3 fatty acids (n-3FA) diets showed ultrastructural degeneration of both asexual and sexual parasite stages. Abnormal shedding of asexual and sexual parasite developmental stages into the cecal lumen was also observed. Ultrastructural degeneration was cha...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050277
更新日期：1997-01-01 00:00:00
abstract：:The histopathological examination of 11 mesenteric lymph nodes from adult sheep infected with immature stages of Linguatula serrata revealed acute and chronic lesions with the presence of bacterial colonies and yeast cells. Bacteria were mainly present in acute, hemorrhagic, or necrotic lesions while yeast cells were ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-0951-2
更新日期：2008-05-01 00:00:00
abstract：:Cryptosporidium and Giardia are ubiquitous parasites that infect humans and animals. Few reports are available on the prevalence of these two protozoan parasites in yaks (Bos grunniens). In this study, 344 faecal samples were collected from yaks with diarrhoea in the Chenduo and Nangqian counties of Qinghai Province, ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5861-3
更新日期：2018-06-01 00:00:00
abstract：:Infections with the metastrongyloid nematode Aelurostrongylus abstrusus in cats have been reported sporadically from Germany. To assess the occurrence and regional geographical distribution of A. abstrusus in Germany, faecal samples from 391 cats with symptoms of respiratory disease were collected from December 2009 t...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3207-0
更新日期：2013-02-01 00:00:00
abstract：:A seasonal investigation on the occurrence of fishborne zoonotic trematodes (FZT) in economically important mono-cultured hybrid catfish and giant gouramy was conducted in the Mekong Delta of Vietnam. Fish from carp poly-culture and intensive small-scale integrated vegetable-aquaculture-animal husbandry farming (VAC) ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0633-5
更新日期：2007-10-01 00:00:00
abstract：:Trichomonas gallinae are parasitic flagellates of importance in wild and domestic birds. The parasite is worldwide distributed, and Columbine birds are its main host. Current research focuses mostly on epidemiological and phylogenetic studies. However, there is still a lack of knowledge regarding parasite-host interac...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06887-x
更新日期：2020-11-01 00:00:00
abstract：:Chagas disease, caused by the protozoan Trypanosoma cruzi, remains a serious public health problem in Latin America. In relation to digestive problems, 4.5% of patients show mega syndromes (megacolon) in the chronic phase. In this article, we evaluated intestinal motility at the acute phase of T. cruzi infection throu...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0829-8
更新日期：2008-03-01 00:00:00
abstract：:The purpose of the present study was to assess the effect of leaf hexane and chloroform extracts of Aegle marmelos, Andrographis lineata, Andrographis paniculata, Cocculus hirsutus, Eclipta prostrata, and Tagetes erecta on repellent, ovicidal, and oviposition-deterrent activities against Culex tritaeniorhynchus Giles ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1690-8
更新日期：2010-01-01 00:00:00
abstract：:Results obtained in experiments testing the efficacy of anti-procyclic-form rabbit sera on the development of homologous and heterologous stocks of Trypanosoma brucei brucei in Glossina morsitans morsitans indicated that this development was affected little, or not at all, by such sera. The absence of effect of anti-p...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00934382
更新日期：1991-01-01 00:00:00
abstract：:An experiment was conducted to study the adjuvant effect of ginsomes on the recombinant profilin in coccidian-infected breeding birds. Three-day-old chickens were vaccinated with Eimeria tenella recombinant profilin antigen (10, 50, and 100 μg per chicken) with or without 50 μg ginsomes per chicken. The boost vaccinat...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2784-7
更新日期：2012-06-01 00:00:00
abstract：:The induction of protective immunity to Leishmania amazonensis was investigated by injection of parasite clones of low and medium virulence into susceptible mice. To this end, L. amazonensis were cloned by limiting dilution and the clones' virulence was evaluated by the course of infection in susceptible mice. Clones ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050321
更新日期：1997-01-01 00:00:00
