Motility and cytoskeletal organisation in the archigregarine Selenidium pygospionis (Apicomplexa): observations on native and experimentally affected parasites.

Abstract:

:Representatives of Apicomplexa perform various kinds of movements that are linked to the different stages of their life cycle. Ancestral apicomplexan lineages, including gregarines, represent organisms suitable for research into the evolution and diversification of motility within the group. The vermiform trophozoites and gamonts of the archigregarine Selenidium pygospionis perform a very active type of bending motility. Experimental assays and subsequent light, electron, and confocal microscopic analyses demonstrated the fundamental role of the cytoskeletal proteins actin and tubulin in S. pygospionis motility and allowed us to compare the mechanism of its movement to the gliding machinery (the so-called glideosome concept) described in apicomplexan zoites. Actin-modifying drugs caused a reduction in the movement speed (cytochalasin D) or stopped the motility of archigregarines completely (jasplakinolide). Microtubule-disrupting drugs (oryzalin and colchicine) had an even more noticeable effect on archigregarine motility. The fading and disappearance of microtubules were documented in ultrathin sections, along with the formation of α-tubulin clusters visible after the immunofluorescent labelling of drug-treated archigregarines. The obtained data indicate that subpellicular microtubules most likely constitute the main motor structure involved in S. pygospionis bending motility, while actin has rather a supportive function.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Kováčiková M,Paskerova GG,Diakin A,Simdyanov TG,Vaškovicová N,Valigurová A

doi

10.1007/s00436-019-06381-z

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

2651-2667

issue

9

eissn

0932-0113

issn

1432-1955

pii

10.1007/s00436-019-06381-z

journal_volume

118

pub_type

杂志文章
  • Molecular identification and phylogenetic analysis of Wuchereria bancrofti from human blood samples in Egypt.

    abstract::Lymphatic filariasis (LF) is a serious vector-borne health problem, and Wuchereria bancrofti (W.b) is the major cause of LF worldwide and is focally endemic in Egypt. Identification of filarial infection using traditional morphologic and immunological criteria can be difficult and lead to misdiagnosis. The aim of the ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5372-7

    authors: Abdel-Shafi IR,Shoieb EY,Attia SS,Rubio JM,Ta-Tang TH,El-Badry AA

    更新日期:2017-03-01 00:00:00

  • Toxicity and potential utility of ivermectin and moxidectin as xenointoxicants against the common bed bug, Cimex lectularius L.

    abstract::The recent resurgence of the common bed bug Cimex lectularius L. throughout western industrialized nations has been facilitated in part by the insect becoming pesticide-resistant. Novel control strategies, including xenointoxication, should be considered to combat C. lectularius. Ivermectin, a U.S. Food and Drug Admin...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-016-5062-x

    authors: Sheele JM,Ridge GE

    更新日期:2016-08-01 00:00:00

  • Larvicidal activity of Blumea eriantha essential oil and its components against six mosquito species, including Zika virus vectors: the promising potential of (4E,6Z)-allo-ocimene, carvotanacetone and dodecyl acetate.

    abstract::The effective and environmentally sustainable control of mosquitoes is a challenge of essential importance. This is due to the fact that some invasive mosquitoes, with special reference to the Aedes genus, are particularly difficult to control, due to their high ecological plasticity. Moreover, the indiscriminate over...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5395-0

    authors: Benelli G,Govindarajan M,Rajeswary M,Senthilmurugan S,Vijayan P,Alharbi NS,Kadaikunnan S,Khaled JM

    更新日期:2017-04-01 00:00:00

  • Cloning, sequencing and recombinant expression of the open reading frame encoding a novel member of the Sarcocystis muris (Apicomplexa) microneme lectin family.

    abstract::Micronemes are characteristic secretory organelles located within the apical cell region of apicomplexan parasites. The protein contents are exocytosed during an early phase of host cell invasion and contribute to parasite motility and the invasion of target cells. We report here on the cloning and heterologous expres...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-002-0600-0

    authors: Klein H,Mueller S,Loeschner B,Toenjes RR,Braun G,Mueller EC,Otto A,Montag T

    更新日期:2003-05-01 00:00:00

  • Characterisation of single domain ATP-binding cassette protien homologues of Theileria parva.

    abstract::Two distinct genes encoding single domain, ATP-binding cassette transport protein homologues of Theileria parva were cloned and sequenced. Neither of the genes is tandemly duplicated. One gene, TpABC1, encodes a predicted protein of 593 amino acids with an N-terminal hydrophobic domain containing six potential membran...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360100433

    authors: Kibe MK,Macklin M,Gobright E,Bishop R,Urakawa T,ole-MoiYoi OK

    更新日期:2001-09-01 00:00:00

  • Molecular characterization of Trypanosoma cruzi and infection rate of the vector Triatoma dimidiata in Costa Rica.

    abstract::According to the genetic characterization by the analysis of the miniexon gene, strains of Trypanosoma cruzi can be classified into six discrete typing units (DTUs), and the DTU 1 into four distinct genotypes associated with different life cycles. While Chagas disease is endemic in Costa Rica, T. cruzi isolates from t...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-012-3000-0

    authors: Zuriaga MÁ,Blandón-Naranjo M,Valerio-Campos I,Salas R,Zeledón R,Bargues MD

    更新日期:2012-10-01 00:00:00

  • Helminth parasitism in two closely related South African rodents: abundance, prevalence, species richness and impinging factors.

    abstract::We investigated patterns of helminth infection in two closely related rodents (social Rhabdomys pumilio occurring mainly in xeric habitats and solitary R. dilectus occurring mainly in mesic habitats) at 20 localities in different biomes of South Africa and asked if between-species differences were mainly caused by dif...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5419-9

    authors: Spickett A,Junker K,Krasnov BR,Haukisalmi V,Matthee S

    更新日期:2017-04-01 00:00:00

  • Sarcocystis cymruensis: discovery in Western Hemisphere in the Brown rat (Rattus norvegicus) from Grenada, West Indies: redescription, molecular characterization, and transmission to IFN-γ gene knockout mice via sporocysts from experimentally infected dom

    abstract::Rodents are intermediate hosts for many species of Sarcocystis. Little is known of Sarcocystis cymruensis that uses the Brown rat (Rattus norvegicus) as intermediate hosts and the domestic cat (Felis catus) as experimental definitive host. Here, we identified and described Sarcocystis cymruensis in naturally infected ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-018-5799-5

    authors: Antunes Murata FH,Cerqueira-Cézar CK,Thompson PC,Tiwari K,Mowery JD,Verma SK,Rosenthal BM,Sharma RN,Dubey JP

    更新日期:2018-04-01 00:00:00

  • In vitro uptake and autoradiographic localization of tritiated gossypol in Taenia taeniaeformis metacestodes.

    abstract::Gossypol, a natural polyphenolic compound, induces growth-inhibitory and antiparasitic effects in Taenia taeniaeformis metacestodes in vivo and in vitro. We investigated the uptake and localization of [3H]-gossypol in this parasite. Metacestodes were incubated in 10(-5) M [3H]-gossypol at 37 degrees C. Parasites stead...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/BF00932182

    authors: Kulp SK,Rikihisa Y,Lin YC,Moh PP,Li PK,Gu Y

    更新日期:1993-01-01 00:00:00

  • Ethanol-fixed material used for both classical and molecular identification purposes: Eudiplozoon nipponicum (Monogenea: Diplozoidae) as a case parasite species.

    abstract::This study is focused on the feasibility of two treatments of alcohol-fixed monogenean parasites which are intended to be use for the combined morphological and molecular characterizations. The monogenean parasite, Eudiplozoon nipponicum, was selected as a model parasite species; however it is expected that these tech...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-010-1949-0

    authors: Kosková E,Matejusová I,Civánová K,Koubková B

    更新日期:2010-09-01 00:00:00

  • Detection of a gypsy-like sequence in the genome of the cat flea Ctenocephalides felis (Bouché 1835).

    abstract::The gypsy virus of Drosophila melanogaster is the first identified retrovirus of insects. Its infectious properties have been reported, and it is able to cause diverse mutations of the phenotype in the fruit fly. As a typical endogenous retrovirus, it is transmitted vertically as part of the host genome, but horizonta...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-006-0249-1

    authors: Dahl A,Krämer F,Schnieder T

    更新日期:2007-01-01 00:00:00

  • Status of tick distribution in Bangladesh, India and Pakistan.

    abstract::On a global basis, ticks transmit a greater variety of pathogenic microorganisms, protozoa, rickettsiae, spirochaets, and viruses than any other arthropods and are among the most important vectors of diseases affecting livestock, humans, and companion animals. Ticks and tick-borne diseases (TTBDs) affect 80% of the wo...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-007-0684-7

    authors: Ghosh S,Bansal GC,Gupta SC,Ray D,Khan MQ,Irshad H,Shahiduzzaman M,Seitzer U,Ahmed JS

    更新日期:2007-09-01 00:00:00

  • First description of an apical epidermis cone in Paratenuisentis ambiguus (Acanthocephala: Eoacanthocephala) and its phylogenetic implications.

    abstract::The proboscis apex of the eoacanthocephalan parasite Paratenuisentis ambiguus was studied, using electron and light microscopy, for a better understanding of the parasite's attachment at the intestinal wall of its definitive hosts (Anguilla rostrata and A. anguilla). The results suggest the presence of an epidermis co...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/pl00008583

    authors: Herlyn H

    更新日期:2001-04-01 00:00:00

  • The reproduction of Eimeria flavescens and Eimeria intestinalis in suckling rabbits.

    abstract::Suckling rabbits from six litters were orally inoculated at various ages with oocysts of Eimeria flavescens or Eimeria intestinalis. The total number of oocysts in the ceca served to estimate parasite reproduction. The rabbits at 14 and 16 days old remained uninfected, and in 19-day-old animals, low or no oocyst shedd...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-007-0646-0

    authors: Pakandl M,Hlásková L

    更新日期:2007-10-01 00:00:00

  • The field efficacy of garlic extract against Dermanyssus gallinae in layer farms of Babol, Iran.

    abstract::Dermanyssus gallinae (Acari: Mesostigmata) is the most important hematophagous ectoparasite in layer farms in many countries. The reproduction rate of the parasite is rapid and can be completed in a week under favorable conditions. The parasite has direct and indirect effects on birds. It can also act as a vector for ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-014-3759-2

    authors: Faghihzadeh Gorji S,Faghihzadeh Gorji S,Rajabloo M

    更新日期:2014-03-01 00:00:00

  • Occurrence and regional distribution of Aelurostrongylus abstrusus in cats in Germany.

    abstract::Infections with the metastrongyloid nematode Aelurostrongylus abstrusus in cats have been reported sporadically from Germany. To assess the occurrence and regional geographical distribution of A. abstrusus in Germany, faecal samples from 391 cats with symptoms of respiratory disease were collected from December 2009 t...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-012-3207-0

    authors: Barutzki D,Schaper R

    更新日期:2013-02-01 00:00:00

  • Gene structure of Taenia solium paramyosin.

    abstract::Paramyosin is a muscle protein that probably plays a role in the survival of the larval stage of Taenia solium during its prolonged host-parasite relationship. Here we describe the structure of the gene coding for the paramyosin of T. solium. The characterization of two clones obtained from a genomic library showed th...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-002-0761-x

    authors: Vargas-Parada L,Laclette JP

    更新日期:2003-03-01 00:00:00

  • Fatty acid profiles in Leishmania spp. isolates with natural resistance to nitric oxide and trivalent antimony.

    abstract::Fatty acids, especially those from phospholipids (PLFA), are essential membrane components that are present in relatively constant proportions in biological membranes under natural conditions. However, under harmful growth conditions, such as diseases, environmental changes, and chemical exposure, the fatty acid propo...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-013-3621-y

    authors: de Azevedo AF,Dutra JL,Santos ML,Santos Dde A,Alves PB,de Moura TR,de Almeida RP,Fernandes MF,Scher R,Fernandes RP

    更新日期:2014-01-01 00:00:00

  • Factors influencing spatial variation and abundance of a mermithid parasite in sand hoppers.

    abstract::The impact of parasites on host population dynamics depends on local abundance of the parasites, which may vary considerably across spatial scales. In sand hopper populations, mermithid parasites have major impacts on host dynamics, which may vary among spatially separated populations due to the sand hopper's wide, pa...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-014-4254-5

    authors: Rasmussen TK,Randhawa HS

    更新日期:2015-03-01 00:00:00

  • Mosquitoes (Diptera: Culicidae) of metropolitan Hamburg, Germany.

    abstract::In Europe, mosquito-related public health concerns are growing due to the increasing spread of invasive mosquito species and the recent emergence of mosquito-borne arboviruses. A vital backbone in the assessment of these issues is detailed knowledge of the mosquito fauna, i.e. regional mosquito inventories. It was the...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-014-3952-3

    authors: Krüger A,Börstler J,Badusche M,Lühken R,Garms R,Tannich E

    更新日期:2014-08-01 00:00:00

  • Parasite communities of the neotropical cormorant Phalacrocorax brasilianus (Gmelin) (Aves, Phalacrocoracidae) from two coastal lagoons in Guerrero state, Mexico.

    abstract::The parasite community structure of the neotropical cormorant, Phalacrocorax brasilianus, from two lagoons (Coyuca and Tres Palos) from Guerrero state, México, was examined. Fourteen species of adult helminths (6,391 individuals) from 48 cormorants were identified: 9 digeneans, 1 acanthocephalan, 1 cestode, and 3 nema...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-011-2377-5

    authors: Violante-González J,Monks S,Gil-Guerrero S,Rojas-Herrera A,Flores-Garza R,Larumbe-Morán E

    更新日期:2011-11-01 00:00:00

  • Plasmodium helical interspersed subtelomeric family-an enigmatic piece of the Plasmodium biology puzzle.

    abstract::Plasmodium falciparum (Pf) refurbishes the infected erythrocytes by exporting a myriad of parasite proteins to the host cell. A novel exported protein family 'Plasmodium Helical Interspersed Subtelomeric' (PHIST) has gained attention for its significant roles in parasite biology. Here, we have collected and analysed a...

    journal_title:Parasitology research

    pub_type: 杂志文章,评审

    doi:10.1007/s00436-019-06420-9

    authors: Kumar V,Behl A,Sharma R,Sharma A,Hora R

    更新日期:2019-10-01 00:00:00

  • Echinococcus multilocularis (Cestoda, Cyclophyllidea, Taeniidae): functional ultrastructure of the penetration glands and nerve cells within the oncosphere.

    abstract::The fine structure of the infective hexacanths of Echinococcus multilocularis was examined with particular emphasis on the functional ultrastructure of penetration glands and nerve cells directly involved in the mechanism of initial host infection. The oncosphere contains two types of penetration glands, PG1 and PG2, ...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-018-5957-9

    authors: Świderski Z,Miquel J,Azzouz-Maache S,Pétavy AF

    更新日期:2018-08-01 00:00:00

  • Morphometric and molecular characteristics of Labeonema synodontisi n. comb. (Nematoda: Atractidae) from the West African fishes.

    abstract::Numerous nematodes were found in the rectum of three fish species Synodontis ocellifer, S. nigrita, and S. schall (Mochokidae, Siluriformes) from the Gambia River and Mare Simenti, National Park Niokolo Koba, Senegal. A nematode species Raillietnema synodontisi Vassiliadès, 1973 (host S. ocellifer), is redescribed usi...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-007-0869-0

    authors: Koubková B,Barus V,Hodová I,Simková A

    更新日期:2008-04-01 00:00:00

  • Gastrointestinal parasites of captive European bison Bison bonasus (L.) with a sign of reduced efficacy of Haemonchus contortus to fenbendazole.

    abstract::The history of European bison Bison bonasus Linnaeus, 1758 has been stormy since its extinction in the wild after the First World War. Due to the fact that the species was restored from just 12 founders, further expansion has suffered from low genetic variability, rendering the bison vulnerable to various pathogens du...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-017-5663-z

    authors: Pyziel AM,Björck S,Wiklund R,Skarin M,Demiaszkiewicz AW,Höglund J

    更新日期:2018-01-01 00:00:00

  • A human schwannoma cell line supports the in vitro adhesion of Plasmodium falciparum infected erythrocytes to chondroitin-4-sulfate.

    abstract::The paucity of human cell lines expressing defined receptors for the cytoadhesion of erythrocytes infected with the human malarial parasite Plasmodium falciparumhas hampered the investigation of this important virulence property. Here, we investigate a permanent cell line derived from a human, malignant schwannoma, te...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-002-0744-y

    authors: Andrews KT,Viebig NK,Wissing F,Klatt N,Oster N,Wickert H,Knolle P,Lanzer M

    更新日期:2003-02-01 00:00:00

  • Removal of hydrogen peroxide by a 1-cysteine peroxiredoxin enzyme of the filarial parasite Dirofilaria immitis.

    abstract::Prior studies have shown that filarial nematodes can effectively metabolize hydrogen peroxide in excess of that generated by activated host cells. However, the mechanisms of H2O2 removal by the filarial parasites are unclear. Herein we report the results of studies carried out on the biochemical activity and on immuno...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s004360050032

    authors: Chandrashekar R,Tsuji N,Morales TH,Carmody AB,Ozols VO,Welton J,Tang L

    更新日期:2000-03-01 00:00:00

  • Larvicidal activity of micronized aqueous suspension of calcium hydroxide against Aedes aegypti and Culex quinquefasciatus (Diptera: Culicidae).

    abstract::In the search of alternatives for the control of mosquitoes of medical importance, we evaluated the larvicidal activity of micronized suspensions of calcium hydroxide [Ca(OH)₂] against Aedes aegypti and Culex quinquefasciatus. Tests conducted under laboratory conditions determined a LC50 = 0.027% (LC90 = 0.096%) for A...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-011-2593-z

    authors: Estrada-Aguilar A,Sánchez-Manzano RM,Martínez-Ibarra JA,Camacho AD,Márquez-Navarro A,Nogueda-Torres B

    更新日期:2012-03-01 00:00:00

  • Evaluation of larvicidal activity of Acalypha alnifolia Klein ex Willd. (Euphorbiaceae) leaf extract against the malarial vector, Anopheles stephensi, dengue vector, Aedes aegypti and Bancroftian filariasis vector, Culex quinquefasciatus (Diptera: Culicid

    abstract::The leaf extract of Acalypha alnifolia with different solvents - hexane, chloroform, ethyl acetate, acetone and methanol - were tested for larvicidal activity against three important mosquitoes such as malarial vector, Anopheles stephensi, dengue vector, Aedes aegypti and Bancroftian filariasis vector, Culex quinquefa...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-011-2525-y

    authors: Kovendan K,Murugan K,Vincent S

    更新日期:2012-02-01 00:00:00

  • Histopathological studies in two strains of semi-immune mice infected with Plasmodium berghei ANKA after chronic exposure.

    abstract::To mimic a human malaria infection in the endemic condition, two strains of mice (Balb/c and CBA) were infected and treated several times to generate so-called semi-immune status. As previously reported, neither mice (Balb/c and CBA) strain showed cerebral malaria, even in the susceptible C57BL/6 (B6). The significant...

    journal_title:Parasitology research

    pub_type: 杂志文章

    doi:10.1007/s00436-010-2121-6

    authors: Helegbe GK,Yanagi T,Senba M,Huy NT,Shuaibu MN,Yamazaki A,Kikuchi M,Yasunami M,Hirayama K

    更新日期:2011-04-01 00:00:00