Abstract：
:The paucity of human cell lines expressing defined receptors for the cytoadhesion of erythrocytes infected with the human malarial parasite Plasmodium falciparumhas hampered the investigation of this important virulence property. Here, we investigate a permanent cell line derived from a human, malignant schwannoma, termed HMS-97, and show that this cell line expresses chondroitin-4-sulfate as the only surface receptor to which P. falciparum-infected erythrocytes can cytoadhere. Other common receptors for parasite adhesion, including CD36, vascular cellular adhesion molecule-1 (VCAM), intercellular adhesion molecule-1 (ICAM-1), and E-selectin are absent. Thus, HMS-97 cells are a useful tool for the study of P. falciparum adhesion to chondoitin-4-sulfate, the main receptor for parasite sequestration in the placenta. As chondoitin-4-sulfate can be readily cleaved from the cells, HMS-97 cells are also an ideal system for expressing recombinant adhesion receptors and studying their function in binding assays.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Andrews KT,Viebig NK,Wissing F,Klatt N,Oster N,Wickert H,Knolle P,Lanzer Mdoi
10.1007/s00436-002-0744-ysubject
Has Abstractpub_date
2003-02-01 00:00:00pages
188-93issue
3eissn
0932-0113issn
1432-1955journal_volume
89pub_type
杂志文章abstract：:Aelurostrongylus abstrusus (Nematoda, Metastrongyloidea) causes verminous pneumonia in cats worldwide. This study evaluated the seroprevalence of A. abstrusus antibodies in 220 stray and free-roaming cats from insular (Mykonos, Crete, Skopelos) and continental (Thessaloniki, Attica) Greece. The results were compared w...
journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2020-09-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1015-3
更新日期：2008-08-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4311-8
更新日期：2015-04-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1024-2
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journal_title：Parasitology research
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Parasitology research
pub_type： 杂志文章
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1250-1
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3444-x
更新日期：2013-07-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06791-4
更新日期：2020-09-01 00:00:00
abstract：:The polymerase chain reaction (PCR) assay has turned out to be one of the most potential tools for diagnosis of schistosomiasis. However, the source and metabolic dynamics of Schistosoma japonicum DNA in the blood of hosts is not clear. In this study, rabbit models with monosexual and mixed sexual cercariae infection ...
journal_title：Parasitology research
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更新日期：2013-01-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：1999-04-01 00:00:00
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journal_title：Parasitology research
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更新日期：2014-07-01 00:00:00
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journal_title：Parasitology research
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s00436-010-2072-y
更新日期：2011-01-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2016-12-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：1987-01-01 00:00:00
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journal_title：Parasitology research
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更新日期：2012-06-01 00:00:00
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journal_title：Parasitology research
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更新日期：2015-02-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050336
更新日期：1997-01-01 00:00:00
abstract：:Ticks can significantly affect the health and fitness of the host. Seasonal population dynamics of ticks play a vital role in disease transmission and the shaping of life-history traits of both tick and host. In this study, we examine the seasonal population dynamics of Ixodes hirsti in South Australia. For 2 years, w...
journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2008-09-01 00:00:00
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更新日期：2019-03-01 00:00:00
abstract：:It was determined that there is a relationship between prevalence and mean densities of Trichodina spp. on Merlangius merlangus and organic pollution, measured as levels of nitrite, nitrate and phosphate in the surrounding environment. Monthly, two left anterior gill arcs of 60 M. merlangus (unless otherwise stated) c...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1346-2
更新日期：2005-06-01 00:00:00
