Eimeria vermiformis infection reduces goblet cells by multiplication in the crypt cells of the small intestine of C57BL/6 mice.


:In the gastrointestinal mucosa, mucus produced by goblet cells plays an important role in the defense against various pathogens. It is well known that some helminth parasites are able to up-regulate goblet cell numbers and alter the mucus components. However, the nature of the interactions between the protozoan parasites and goblet cells is still unclear. To clarify this point, we examined the goblet cell response in the small intestinal epithelium in C57BL/6 mice with Eimeria vermiformis infection. On day 6 post-infection (p.i.), we observed E. vermiformis multiplication followed by their destruction within the epithelium of the crypt. However, this was not observed in the villi. There was no evidence that the parasite destroyed the goblet cells; moreover, the number of goblet cells decreased in association with the development of the endogenous stages of E. vermiformis in the jejunum and ileum, but not in the duodenum. During this time, we observed infiltration into the lamina propria by lymphoid cells, such as plasma cells and lymphocytes with some eosinophils, in addition to villous atrophy. A significant reduction of goblet cell numbers occurred on days 8 and 10 p.i. Starting from day 12 p.i., elimination/termination of E. vermiformis was noted, and there was recovery of the villous epithelium along with regeneration of the crypt and goblet cells. The current study examined the reduction of goblet cells and their possible importance in eimerian infections.


Parasitol Res


Parasitology research


Linh BK,Hayashi T,Horii Y




Has Abstract


2009-03-01 00:00:00












  • Cloning and sequence analysis of a lysophospholipase homologue from Schistosoma mansoni.

    abstract::A novel cDNA encoding a lysophospholipase (SmLPLH) homologue has been cloned from the human parasite, Schistosoma mansoni. The predicted primary structure of SmLPLH shares high sequence homology with mammalian lysophospholipases (62%) and also contains aconsensus signature peptide (GXSXG), which is present in all lipa...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Hamdan FF,Ribeiro P

    更新日期:1998-10-01 00:00:00

  • Silica nanoparticle: a potential new insecticide for mosquito vector control.

    abstract::Presently, there is a need for increased efforts to develop newer and effective methods to control mosquito vectors as the existing chemical and biological methods are not as effective as in earlier period owing to different technical and operational reasons. The use of nanomaterial products in various sectors of scie...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Barik TK,Kamaraju R,Gowswami A

    更新日期:2012-09-01 00:00:00

  • Chemical composition, larvicidal evaluation, and adult repellency of endemic Greek Thymus essential oils against the mosquito vector of West Nile virus.

    abstract::The volatile metabolites of Greek wild growing Thymus leucospermus and Thymus teucrioides subsp. candilicus were determined by gas chromatography and gas chromatography-mass spectrometry. The monoterpene hydrocarbon p-cymene (64.2%) dominated T. leucospermus oil, followed by γ-terpinene (7.9%), thymol (4.8%), and born...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Pitarokili D,Michaelakis A,Koliopoulos G,Giatropoulos A,Tzakou O

    更新日期:2011-08-01 00:00:00

  • Reactive nitrogen intermediates in experimental trichomoniasis induced with isolates from symptomatic and asymptomatic women.

    abstract::Trichomoniasis is the interplay between the infecting parasite, Trichomonas vaginalis, and the host, on which the clinical presentation of the disease depends. Although the clinical spectrum varies from an asymptomatic state to mild, moderate or severe symptoms, the exact virulence markers of T. vaginalis have not bee...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Malla N,Valadkhani Z,Harjai K,Sharma S,Gupta I

    更新日期:2004-09-01 00:00:00

  • Diagnosis of Plasmodium falciparum malaria in pregnancy in sub-Saharan Africa: the challenges and public health implications.

    abstract::Plasmodium falciparum malaria in pregnancy is a major public health problem in sub-Saharan Africa and represents enormous diagnostic challenge. The objective of this report was to review scientific data from studies conducted in sub-Saharan Africa on the diagnosis of malaria in pregnancy within the last two decades (1...

    journal_title:Parasitology research

    pub_type: 杂志文章,评审


    authors: Uneke CJ

    更新日期:2008-02-01 00:00:00

  • DNA barcoding and molecular evolution of mosquito vectors of medical and veterinary importance.

    abstract::Mosquitoes (Diptera: Culicidae) are a key threat for millions of people worldwide, since they act as vectors for devastating pathogens and parasites. The standard method of utilisation of morphological characters becomes challenging due to various factors such as phenotypical variations. We explored the complementary ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Murugan K,Vadivalagan C,Karthika P,Panneerselvam C,Paulpandi M,Subramaniam J,Wei H,Aziz AT,Alsalhi MS,Devanesan S,Nicoletti M,Paramasivan R,Parajulee MN,Benelli G

    更新日期:2016-01-01 00:00:00

  • Renin angiotensin system molecules and nitric oxide local interactions in the adrenal gland of Trypanosoma cruzi infected rats.

    abstract::Chagas disease (CD) is a tropical zoonosis caused by the protozoan Trypanosoma cruzi. Severe autonomic dysfunction like reduced cardiac catecholamine-containing or acetylcholinesterase-positive innervation have been reported in CD. Renin-angiotensin system (RAS) seems to participate in the regulation of adrenal catech...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Miranda AS,Camargos ERS,Marzano LAS,Marzano ACS,da Silva Oliveira B,Ferreira RN,Martinelli PM,Teixeira AL,Rachid MA,Simões E Silva AC

    更新日期:2020-01-01 00:00:00

  • Ticks and tick-borne pathogens infecting livestock and dogs in Tchicala-Tcholoanga, Huambo Province, Angola.

    abstract::The diversity of ticks and tick-borne pathogens (TBPs) infesting domestic animals in Tchicala-Tcholoanga, Angola, in 2016 was investigated. Seventeen tick species were recorded, Amblyomma pomposum being the most abundant on cattle (40%), goats (38%) and sheep (35%); Rhipicephalus turanicus was the most abundant on dog...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Sili G,Byaruhanga C,Horak I,Steyn H,Chaisi M,Oosthuizen MC,Neves L

    更新日期:2021-01-08 00:00:00

  • Chemical composition and assessment of larvicidal and repellent capacity of 14 Lamiaceae essential oils against Aedes albopictus.

    abstract::In the current laboratory study, 14 essential oils (EOs) derived from 12 Lamiaceae plant species and their major components were screened for their larvicidal and repellent properties against Aedes albopictus, an invasive mosquito species of great medical importance. The results of toxicity bioassays revealed that the...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Giatropoulos A,Kimbaris A,Michaelakis Α,Papachristos DP,Polissiou MG,Emmanouel N

    更新日期:2018-06-01 00:00:00

  • Molecular detection of Anaplasma platys, Anaplasma phagocytophilum and Wolbachia sp. but not Ehrlichia canis in Croatian dogs.

    abstract::The bacteria Anaplasma platys, Anaplasma phagocytophilum and Ehrlichia canis are tick-borne agents that cause canine vector-borne disease. The prevalence of these pathogens in South Eastern Europe is unknown with the exception of an isolated case of A. platys detected in a dog imported into Germany from Croatia. To ga...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Huber D,Reil I,Duvnjak S,Jurković D,Lukačević D,Pilat M,Beck A,Mihaljević Ž,Vojta L,Polkinghorne A,Beck R

    更新日期:2017-11-01 00:00:00

  • Host cells of Toxoplasma gondii encystation in infected primary culture from mouse brain.

    abstract::In order to identify brain cell types that serve as host cells of Toxoplasma gondii encystation primary cultures from murine brain were infected and stained for neural and parasite stage-specific markers. In mixed culture inoculated with T. gondii tachyzoites, MAP2+ neurons, GFAP+ astrocytes, F4/80+ microglia, and O1+...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Fischer HG,Nitzgen B,Reichmann G,Gross U,Hadding U

    更新日期:1997-01-01 00:00:00

  • Status of babesiosis among domestic herbivores in Iran: a systematic review and meta-analysis.

    abstract::Babesiosis is a protozoal disease caused by Babesia spp. in mammals and humans worldwide. It is one of the most important tick-borne diseases, which affects livestock productions, reproductions, and accordingly failing economy. In this, systematic review and meta-analysis, study, the prevalence of babesiosis among dom...

    journal_title:Parasitology research

    pub_type: 杂志文章,meta分析,评审


    authors: Haghi MM,Etemadifar F,Fakhar M,Teshnizi SH,Soosaraei M,Shokri A,Hajihasani A,Mashhadi H

    更新日期:2017-04-01 00:00:00

  • Spatial distribution and seasonality of Biomphalaria spp. in São Luís (Maranhão, Brazil).

    abstract::Two of the three vector species of Schistosoma mansoni Sambon, 1907 in Brazil occur in the state of Maranhão: Biomphalaria glabrata (Say, 1818) and Biomphalaria straminea (Dunker, 1848). For the implementation of effective measures to combat schistosomiasis, it is necessary to identify the spatial and seasonal dynamic...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: David NF,Cantanhede SPD,Monroe NB,Pereira LPLA,Silva-Souza N,Abreu-Silva AL,de Oliveira VM,Tchaicka L

    更新日期:2018-05-01 00:00:00

  • Trypanosoma acomys (Wenyon, 1909): reproductive forms and course of parasitemia in the natural host Acomys cahirinus (Desmarest, 1819).

    abstract::Trypanosoma acomys (Stercoraria, Trypanosomatidae) was studied in the laboratory-bred spiny mouse Acomys cahirinus. Only trypomastigotes were found in peripheral blood, whereas the thymus of experimentally infected A. cahirinus showed amastigote syncytial reproductive forms whose nuclei of nuclei ranged from 2 to 128....

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Abdallah MA,Abdel-Hafez SK,al-Yaman FM

    更新日期:1989-01-01 00:00:00

  • Characterization of Myxidium spinibarba sp. nov. (Cnidaria, Myxosporea, Myxidiidae) from Spinibarbus sinensis (Bleeker, 1871) in Chongqing China.

    abstract::In the present study, we described a new species of Myxidium Bütschli, 1882, obtained from the gallbladder of Spinibarbus sinensis (Bleeker, 1871) from the Jialing River in Chongqing, China. Myxidium spinibarba sp. nov. was identified based on morphological and SSU rDNA sequence data. The mature myxospores were fusifo...

    journal_title:Parasitology research

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    authors: Chen W,Yang C,Zhao Y

    更新日期:2020-05-01 00:00:00

  • Blood-feeding patterns of Culex quinquefasciatus and other culicines and implications for disease transmission in Mwea rice scheme, Kenya.

    abstract::Studies were conducted in Mwea Rice Scheme, Kenya during the period April 2005 and January 2007 to determine the host-feeding pattern of culicine mosquitoes. Mosquitoes were collected indoors and outdoors and tested for human, bovine, goat, and donkey blood meals by an Enzyme-Linked Immunosorbent Assay. A total of 1,7...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Muturi EJ,Muriu S,Shililu J,Mwangangi JM,Jacob BG,Mbogo C,Githure J,Novak RJ

    更新日期:2008-05-01 00:00:00

  • Myiasis in humans-a global case report evaluation and literature analysis.

    abstract::Myiasis refers to the infestation of living humans and vertebrates with fly larvae that feed on necrotic or vital tissue of the host. Since the invasion of new fly species in Europe is currently being observed, which live obligatorily parasitically or are close relatives of such species, the aim of this study is to ob...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Bernhardt V,Finkelmeier F,Verhoff MA,Amendt J

    更新日期:2019-02-01 00:00:00

  • Molecular identification and phylogenetic analysis of Wuchereria bancrofti from human blood samples in Egypt.

    abstract::Lymphatic filariasis (LF) is a serious vector-borne health problem, and Wuchereria bancrofti (W.b) is the major cause of LF worldwide and is focally endemic in Egypt. Identification of filarial infection using traditional morphologic and immunological criteria can be difficult and lead to misdiagnosis. The aim of the ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Abdel-Shafi IR,Shoieb EY,Attia SS,Rubio JM,Ta-Tang TH,El-Badry AA

    更新日期:2017-03-01 00:00:00

  • Helminth parasitism in two closely related South African rodents: abundance, prevalence, species richness and impinging factors.

    abstract::We investigated patterns of helminth infection in two closely related rodents (social Rhabdomys pumilio occurring mainly in xeric habitats and solitary R. dilectus occurring mainly in mesic habitats) at 20 localities in different biomes of South Africa and asked if between-species differences were mainly caused by dif...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Spickett A,Junker K,Krasnov BR,Haukisalmi V,Matthee S

    更新日期:2017-04-01 00:00:00

  • Inheritance of pyrethroid resistance and a sodium channel gene mutation in the cattle tick Boophilus microplus.

    abstract::A substitution (Phe-->Ile) within the sodium channel gene sequence has been associated with pyrethroid resistance in Boophilus microplus. The aim of the present study was to analyze the inheritance of pyrethroid resistance and the mutant allele, on reciprocal crosses of a susceptible (SS) and a resistant (RR) strain. ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Aguilar-Tipacamú G,Miller RJ,Hernández-Ortiz R,Rodriguez-Vivas RI,Vásquez-Peláez C,García-Vázquez Z,Olvera-Valencia F,Rosario-Cruz R

    更新日期:2008-08-01 00:00:00

  • Investigations into the production and function of leukotrienes during histotropic development of Oesophagostomum dentatum.

    abstract::The dynamics of production and excretion of leukotrienes by parasitic larvae of Oesophagostomum dentatum and their role for the development of the larvae were studied. Larvae were cultured in vitro to the fourth stage (L4). Leukotriene B4 (LTB4) was detected in homogenates and in supernatant of larvae, with the homoge...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Daugschies A

    更新日期:1996-01-01 00:00:00

  • Electron microscopic study of Tetratrichomonas didelphidis and its interaction with a prokaryotic cell.

    abstract::Tetratrichomonas didelphidis is a flagellate protozoan found in the intestine of the opossum. The parasite lives in a hostile and stressed environment, where it interacts with microorganisms and can survive under extreme conditions for growth, involving strict anaerobiosis or equilibration with air and abundance or ab...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Tasca T,De Carli GA

    更新日期:2004-01-01 00:00:00

  • Morphological characterization and first molecular identification of the eleven Eimeria species that infect sheep from Mexico.

    abstract::Within livestock production, enteric diseases play an important role, since they cause severe economic losses due to mortality, growth depression, and reduction in the conversion rate. Coccidiosis caused by Eimeria spp. is a parasitic disease of high morbidity that affects various animal species, including sheep. In s...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Trejo-Huitrón G,Bautista-Gómez LG,Martínez-Castañeda JS,Romero-Núñez C,Trejo-Castro L,Espinosa-Ayala E

    更新日期:2020-01-01 00:00:00

  • Tetra disseminated microsporidiosis: a novel disease in ornamental fish caused by Fusasporis stethaprioni n. gen. n. sp.

    abstract::A novel microsporidial disease was documented in two ornamental fish species, black tetra Gymnocorymbus ternetzi Boulenger 1895 and cardinal tetra Paracheirodon axelrodi Schultz 1956. The non-xenoma-forming microsporidium occurred diffusely in most internal organs and the gill, thus referring to the condition as tetra...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Lovy J,Yanong RPE,Stilwell JM,Waltzek TB,Shelley JP,Pouder DB,Wolf JC,Camus AC

    更新日期:2021-01-08 00:00:00

  • The metacercariae of sibling species of Meiogymnophallus, including M. rebecqui comb. nov. (Digenea: Gymnophallidae), and their effects on closely related Cerastoderma host species (Mollusca: bivalvia).

    abstract::The morphology and ecology are described for four sibling species of digenean metacercariae: Meiogymnophallus minutus (Cobbold 1859), M. strigatus (Lebour 1908) from the estuarine cockle Cerastoderma edule L. and M. fossarum (Bartoli, 1965) and M. rebecqui (Bartoli, 1983) comb. nov. from the brackish water lagoon cock...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Bowers EA,Bartoli P,Russell-Pinto F,James BL

    更新日期:1996-01-01 00:00:00

  • Histopathological studies in two strains of semi-immune mice infected with Plasmodium berghei ANKA after chronic exposure.

    abstract::To mimic a human malaria infection in the endemic condition, two strains of mice (Balb/c and CBA) were infected and treated several times to generate so-called semi-immune status. As previously reported, neither mice (Balb/c and CBA) strain showed cerebral malaria, even in the susceptible C57BL/6 (B6). The significant...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Helegbe GK,Yanagi T,Senba M,Huy NT,Shuaibu MN,Yamazaki A,Kikuchi M,Yasunami M,Hirayama K

    更新日期:2011-04-01 00:00:00

  • Differential diagnosis of cystic and alveolar echinococcosis using an immunochromatographic test based on the detection of specific antibodies.

    abstract::Human cystic and alveolar echinococcoses are zoonotic diseases caused by the larval stages of Echinococcus granulosus and Echinococcus multilocularis, respectively. As the diseases are co-endemic in many areas of the world, a simple and rapid test for the differential diagnosis of cystic echinococcosis (CE) and alveol...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Wang JY,Gao CH,Steverding D,Wang X,Shi F,Yang YT

    更新日期:2013-10-01 00:00:00

  • Lipoptena cervi (Diptera), a potential vector of Megatrypanum trypanosomes of deer (Cervidae).

    abstract::In three different areas in northern Germany, hippoboscids were collected from red deer (Cervus elaphus). Typanosomatids were demonstrated in the midgut and hindgut of 9/37 Lipoptena cervi. The trypanosomatids were morphologically similar to vector forms of the subgenus Megatrypanum that had been found in tabanids at ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Böse R,Petersen K

    更新日期:1991-01-01 00:00:00

  • Development of improved methods for delivery of Trichuris muris to the laboratory mouse.

    abstract::Murine immunological responses to experimental infection with Trichuris muris and the effects of the resident microbiota on these responses are of increasing interest. For these studies, accurate dose delivery and improved sterilization of inocula are essential to prevent co-infection with unknown contaminants. We fou...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Kopper JJ,Mansfield LS

    更新日期:2010-10-01 00:00:00

  • Molecular characterization and expression pattern of an odorant receptor from the myiasis-causing blowfly, Lucilia sericata (Diptera: Calliphoridae).

    abstract::The blowfly Lucilia sericata (Diptera: Calliphoridae) is a facultative ectoparasite that causes myiasis in both man and animals, leading to serious human health problems and economic losses in the livestock industry. Like other insects, olfaction of this species plays an important role in host location and is presumab...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Wang X,Zhong M,Wen J,Cai J,Jiang H,Liu Y,Aly SM,Xiong F

    更新日期:2012-02-01 00:00:00