Abstract：
:Chagas' disease, which is an important health problem in humans, is caused by the protozoan Trypanosoma cruzi. The cellular and molecular mechanisms, involved in the selective tropism of T. cruzi to different organs remain largely unknown. In this study we designed a PCR-based molecular diagnosis method in order to study the tropism and growth kinetics of T. cruzi in a murine model infected with parasites isolated from an endemic area of Mexico. The growth kinetics and parasite tropism of T. cruzi were also evaluated in the blood and other tissues. We observed that T. cruzi isolates from the Western Mexico showed a major tropism to mouse heart and skeletal muscles in this murine model.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Vera-Cruz JM,Magallón-Gastelum E,Grijalva G,Rincón AR,Ramos-García C,Armendáriz-Borunda Jdoi
10.1007/s00436-002-0787-0subject
Has Abstractpub_date
2003-04-01 00:00:00pages
480-6issue
6eissn
0932-0113issn
1432-1955journal_volume
89pub_type
杂志文章abstract：:In this study, we screened field-caught mosquitoes for presence of Dirofilaria spp. by using a polymerase chain reaction (PCR) assay. Potential occurrence of Dirofilaria repens and Dirofilaria immitis microfilariae was examined in 3,600 mosquitoes of eight species (Aedes vexans, Aedes cinereus, Aedes rossicus, Culex p...
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1007/BF00931794
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pub_type： 杂志文章
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更新日期：2010-04-01 00:00:00
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更新日期：2010-05-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2008-10-01 00:00:00
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journal_title：Parasitology research
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更新日期：2012-03-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章,随机对照试验
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journal_title：Parasitology research
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abstract：:The biochemical and structural changes that occur during the conversion of Toxoplasma gondii tachyzoites to bradyzoites and the formation of tissue cyst are not well understood. Maintaining cells infected with T. gondii type II and III strains under stress conditions induces the tachyzoite-bradyzoite in vitro differen...
journal_title：Parasitology research
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更新日期：2018-02-01 00:00:00
abstract：:Adult worm extract from Ascaris suum (Asc) has immunosuppressive activity and elicits Th2/IL-4/IL-10 response. This study evaluated the prophylactic and therapeutic effect of Asc in a murine model of concanavalin A (ConA)-induced autoimmune hepatitis (AIH). BALB/c mice received ConA, iv, (20 mg/kg), and three groups o...
journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2014-09-01 00:00:00
abstract：:In this study, the antigenic mosaic of the vesicular fluid (VF) and hydrosoluble cyst-wall extract (CWE) of T. crassiceps (Tc; harvested from mice) and T. saginata (Ts) metacestodes was analyzed by combined precipitation maps developed in single and bidimensional immunoelectrophoresis against the respective rabbit ant...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931168
更新日期：1989-01-01 00:00:00
