Abstract:
:Gonadectomized male laboratory rats were given 0.06 mg/kg estradiol benzoate daily for 14 days before being inoculated with 50 third-stage larvae of Parastrongylus malaysiensis. Hormone treatment was continued until the rats were killed. The numbers of larvae in the brain and of adult worms in the pulmonary area of the rats were determined every 7 days after the inoculation. It was found that the rats treated daily with estradiol benzoate had significantly and consistently higher numbers of larvae and adult worms as compared with the controls. The number of total leukocytes increased significantly after the rats were infected. The results show that estradiol-treated rats become susceptible to P. malaysiensis infection, which may indicate that the immunosuppressive effects of testosterone observed in earlier studies may partly be caused by estradiol that was peripherally aromatized from testosterone.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Kamis AB,Ahmad RA,Badrul-Munir MZdoi
10.1007/BF00932628subject
Has Abstractpub_date
1994-01-01 00:00:00pages
74-7issue
1eissn
0932-0113issn
1432-1955journal_volume
80pub_type
杂志文章abstract::Intraspecific and interspecific effects on the growth and body size of helminths are rarely studied in natural situations, yet knowing what determines helminth sizes and thus fecundity is crucial to our understanding of helminth ecology and epidemiology. The determinants of average individual worm mass were investigat...
journal_title:Parasitology research
pub_type: 杂志文章
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journal_title:Parasitology research
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journal_title:Parasitology research
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章
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journal_title:Parasitology research
pub_type: 杂志文章
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更新日期:2013-05-01 00:00:00
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journal_title:Parasitology research
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journal_title:Parasitology research
pub_type: 杂志文章,评审
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journal_title:Parasitology research
pub_type: 杂志文章
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journal_title:Parasitology research
pub_type: 杂志文章
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journal_title:Parasitology research
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更新日期:1988-01-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
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更新日期:1991-01-01 00:00:00
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journal_title:Parasitology research
pub_type: 杂志文章
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journal_title:Parasitology research
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更新日期:2015-11-01 00:00:00