Abstract:
:The recent resurgence of the common bed bug Cimex lectularius L. throughout western industrialized nations has been facilitated in part by the insect becoming pesticide-resistant. Novel control strategies, including xenointoxication, should be considered to combat C. lectularius. Ivermectin, a U.S. Food and Drug Administration (FDA)-approved treatment for several human parasites, and the antiparasitic drug moxidectin, currently being explored in human clinical trials, were evaluated for efficacy against C. lectularius. Results showed that C. lectularius fed on ivermectin or moxidectin blood concentrations of >25 ng/mL and had significantly higher mortality (50-100 %) than controls (0-6 %) by day 13. Bed bugs that survived a blood meal containing >2.5 ng/mL of ivermectin suffered long-term sequelae including reduced fecundity, feeding difficulty, and incomplete ecdysis. Some insects that survived a blood meal containing ≤75 ng/mL moxidectin were able to feed and reproduce.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Sheele JM,Ridge GEdoi
10.1007/s00436-016-5062-xsubject
Has Abstractpub_date
2016-08-01 00:00:00pages
3071-81issue
8eissn
0932-0113issn
1432-1955pii
10.1007/s00436-016-5062-xjournal_volume
115pub_type
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journal_title:Parasitology research
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更新日期:2020-05-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章,评审
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journal_title:Parasitology research
pub_type: 杂志文章
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更新日期:2008-07-01 00:00:00
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journal_title:Parasitology research
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更新日期:2007-01-01 00:00:00